Abstract:
PURPOSE OF REVIEW:Improving our understanding of factors driving fat gain in young children should increase our ability to manage the rising problem of obesity. Accordingly, studies associating timing of adiposity rebound with later obesity are reviewed. RECENT FINDINGS:Investigations in many countries have confirmed that early adiposity rebound increases risk of high blood pressure and obesity in young adults. The magnitude of the effect can be substantial (>3 body mass index units at 18-21 years) for those undergoing early (<5 years of age) compared with late (>7 years of age) rebound. Early rebound is also associated with impaired glucose tolerance and diabetes in adulthood. Because adiposity rebound is determined using serial measurements of body mass index, the actual changes in body composition occurring during this time are obscured. Recent data show that changing body mass index during adiposity rebound is due to higher than average deposition of weight rather than slowing of the rate of height gain. Moreover, this increased weight gain occurs because of rapid deposition of fat rather than lean tissue, with early rebounders gaining fat mass at almost three times the rate of late rebounders. SUMMARY:Future work is needed to identify reasons for early adiposity rebound. Because high physical activity and low inactivity are associated with lower body fat during the period of adiposity rebound, studies should be undertaken to see whether stepping up activity can slow fat gain, delay the onset of adiposity rebound and lower adult obesity.
journal_name
Curr Opin Clin Nutr Metab Carejournal_title
Current opinion in clinical nutrition and metabolic careauthors
Taylor RW,Grant AM,Goulding A,Williams SMdoi
10.1097/01.mco.0000168391.60884.93subject
Has Abstractpub_date
2005-11-01 00:00:00pages
607-12issue
6eissn
1363-1950issn
1473-6519pii
00075197-200511000-00005journal_volume
8pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Investigations into the regulation of muscle protein synthesis (MPS) are a cornerstone of understanding the control of muscle mass. Rates of MPS are finely tuned according to levels of activity, nutrient availability and health status. For instance, rates of MPS are positively regulated by exercise an...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32834d19bc
更新日期:2012-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Recent clinical trials have furthered our understanding of the role of probiotic and synbiotic therapy across a variety of diverse diseases including antibiotic-associated diarrhea, Clostridium difficile associated diarrhea, acute pancreatitis, ventilator-associated pneumonia, and sepsis among others....
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32834fcea8
更新日期:2012-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Nonalcoholic fatty liver disease (NAFLD) is the liver epidemic of our time. Diet strongly influences its development and should be a component of any treatment plan. It is crucial to standardize diet recommendations in an evidence-based manner. RECENT FINDINGS:Calorie restriction per se seems benefic...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e3283566614
更新日期:2012-09-01 00:00:00
abstract::The underlying causative agent in the majority of patients with chronic liver disease is ethanol; the rest of the cases are largely viral in aetiology (hepatitis B or C viruses). Nutrition supplementation improves the quality of life and decreases morbidity in chronic liver disease, but evidence that it prolongs long-...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200005000-00011
更新日期:2000-05-01 00:00:00
abstract:PURPOSE OF REVIEW:There is a need to develop a screening tool to assist clinical staff in deciding whether or not a patient in the ICU should be given nutrition support. The purpose of this review is to analyze the recent randomized trials in this context. RECENT FINDINGS:Five trials describe the effect of early suppl...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000041
更新日期:2014-03-01 00:00:00
abstract::Crude measurements of nutritional status, such as body weight, are inadequate to assess the severity and consequence of malnutrition among inflammatory bowel disease patients. Functional deficiency resulting in osteopenia and muscle weakness have been demonstrated in these patients when compared to controls. Manipulat...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-199809000-00002
更新日期:1998-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The rapid muscle loss that accompanies varying diseased states (cachexia) is due to an imbalance between muscle protein synthesis (MPS) and muscle protein breakdown In the current review, we will discuss and summarize recent evidence in order to provide practical recommendations on exercise and nutrie...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e3283516850
更新日期:2012-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The Scored Patient-Generated Subjective Global Assessment (PG-SGA) is used internationally as the reference method for proactive risk assessment (screening), assessment, monitoring and triaging for interventions in patients with cancer. This review aims to explain the rationale behind and data support...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000389
更新日期:2017-09-01 00:00:00
abstract::Catabolism of fat-free mass affects both the quality of life and survival of patients. Because of variations in fluid status during acute illness, changes in body weight are difficult to evaluate and interpret during treatment. Nutritional assessment should therefore evaluate fat-free and fat mass changes during metab...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200007000-00013
更新日期:2000-07-01 00:00:00
abstract::Milk is the only biomaterial that evolved under the Darwinian selective pressure to nourish growing mammals. The purpose of this article is to review the scientific research that is using new techniques of integrating biological sequence, structure and function, to understand the innovative biology underlying the prod...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200211000-00007
更新日期:2002-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To summarize recent findings that docosahexaenoate (DHA) is the precursor of stereospecific derivatives with anti-inflammatory and cytoprotective properties. RECENT FINDINGS:The docosahexaenoate-derived mediator neuroprotectin D1 is formed in retinal pigment epithelial cells when confronted with oxid...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32802b7030
更新日期:2007-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Growth hormone is a powerful anabolic hormone necessary for normal growth, but its importance in maintaining the cellular and protein mass in adult life is still unclear. However, it is viewed as a drug capable of combating the tissue loss and some metabolic derangements of aging. Growth hormone exces...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200501000-00008
更新日期:2005-01-01 00:00:00
abstract::Home artificial nutrition is a mature technology that has been with us for over a quarter of a century. Its use appears to be more widespread in the USA than in other western countries. Issues of outcome, ethics, and quality of life are increasingly important. Complications continue to be reported, some newly recogniz...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-199909000-00006
更新日期:1999-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Metabolic syndrome (MetS) is associated with increased risk of obesity, type 2 diabetes mellitus and cardiovascular diseases. MetS prevalence has been associated with diet inadequacy. Conversely, the cumulative incidence of MetS has been inversely associated with a Mediterranean-style diet that includ...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000412
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe the evidences for and against the different nutritional and nonnutritional therapeutic approaches for severe alcoholic steatohepatitis, based on data from randomized controlled trials, in order to answer the question posed in the title: 'more of the same or something new?'. RECENT FINDING...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32830b5d1e
更新日期:2008-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Both dietary and nondietary factors contribute to iron deficiency, the most common nutritional deficiency worldwide. Identifying dietary factors associated with iron deficiency is challenging due to the number of components in food affecting iron absorption. This review describes recent advances in di...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e328364f382
更新日期:2013-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Infection and sepsis remain major challenges in the critically ill. How nutritional therapy can effect real clinical outcomes is not easily apparent from the clinical data. Despite reducing infectious incidence, many studies show little difference in meaningful clinical outcomes. RECENT FINDINGS:Conf...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200303000-00009
更新日期:2003-03-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss recent evidence from observational and intervention studies on the relationship between fruit and vegetable (F&V) consumption and metabolic disease. RECENT FINDINGS:Observational studies have consistently demonstrated a modest inverse association between the intake of fruit and leafy green...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000378
更新日期:2017-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews recent epidemiologic and intervention studies addressing the impact of hyperglycemia on morbidity and mortality in critically ill patients. It also discusses a growing body of literature examining why elevated blood glucose occurs in hospitalized patients without previously recogn...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e3281a3bf0a
更新日期:2007-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The mortality and morbidity associated with severe acute malnutrition (SAM) remain high. A summary of recent studies that are of interest to clinicians treating children with SAM is provided. RECENT FINDINGS:Three important themes emerged in 2015: the use of anthropometry in the diagnosis of SAM and ...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000269
更新日期:2016-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Until relatively recently, the only significant source of lactoferrin in the diet was human lactoferrin, provided in breast milk. Today, however, bovine lactoferrin, isolated by dairy technology, as well as recombinant human lactoferrin are commercially available and can be added to foods and clinical...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e328328d13e
更新日期:2009-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章
doi:10.1097/MCO.0000000000000721
更新日期:2020-12-05 00:00:00
abstract:PURPOSE OF REVIEW:To summarize the literature concerning the relationship between meal patterns and childhood obesity. Literature searches of MEDLINE and the Cochrane Library were performed in October 2009 for studies published in the last 18-24 months. RECENT FINDINGS:Available data indicate that not only meal compos...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32833681a2
更新日期:2010-05-01 00:00:00
abstract:PURPOSE OF REVIEW:There are concerns about the rising incidence of obesity in children and their acceptance of healthy foods. Many factors affect children's food acceptance, the most salient are those enabling early exposure to culturally appropriate foods in the weaning or pre-weaning period. Parents, however, have al...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e3282f9e228
更新日期:2008-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Ketone body metabolism is a dynamic and integrated metabolic node in human physiology, whose roles include but extend beyond alternative fuel provision during carbohydrate restriction. Here we discuss the most recent observations suggesting that ketosis coordinates cellular function via epigenomic reg...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000475
更新日期:2018-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The concentrations of plasma-free amino acids, such as branched-chain amino acids and aromatic amino acids, are associated with visceral obesity, insulin resistance, and the future development of diabetes and cardiovascular diseases. This review discusses recent progress in the early assessment of the...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章
doi:10.1097/MCO.0000000000000305
更新日期:2016-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide clinical investigators with an understanding of factors to consider when wishing to add cytokine and inflammatory marker measurements to their studies. RECENT FINDINGS:Inflammation involves complex and coordinated responses of the immune system to tissue damage. In the absence of tools to ...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32833cf3bc
更新日期:2010-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The prevalence of nonalcoholic fatty liver disease is increasing worldwide and there is strong evidence that dietary factors play a role in its pathogenesis. The present review aims to provide a better understanding of how carbohydrates and other macronutrients may affect the disease. RECENT FINDINGS...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e328302f3ec
更新日期:2008-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease. RECENT FINDINGS:Cancer cachexia is a severely debilitating and life-threate...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/01.mco.0000134366.07148.2e
更新日期:2004-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Early interventional trials reported improvements in cardiac and exercise outcomes with inorganic nitrate ingestion. The current review aims to provide a brief update of recent evidence regarding ergogenic and cardiovascular effects of dietary nitrate and practical recommendations. RECENT FINDINGS:Re...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000414
更新日期:2017-11-01 00:00:00