Using trehalose to prevent and treat metabolic function: effectiveness and mechanisms.

abstract：PURPOSE OF REVIEW:Lipidomic profiling of biological samples is increasing in nutritional research applications. 'Lipidomic analyses' however can be quite variable in specific methods and the type of information about the specific lipids that is revealed. The lack of defined and simple terminology to describe aspects of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Aristizabal Henao JJ,Bradley RM,Duncan RE,Stark KD

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Metabolic syndrome (MetS) is associated with increased risk of obesity, type 2 diabetes mellitus and cardiovascular diseases. MetS prevalence has been associated with diet inadequacy. Conversely, the cumulative incidence of MetS has been inversely associated with a Mediterranean-style diet that includ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Goncalves A,Amiot MJ

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Glutamine and arginine are conditionally essential amino acids because depletion occurs in stressed conditions. Intravenous glutamine supplementation reduces morbidity and mortality in critically ill patients fed parenterally. In surgical patients, arginine-enriched diets have beneficial effects, but ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Coëffier M,Déchelotte P

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a concise overview of the polyphenol curcumin for improving arterial health, specifically endothelial function and arterial stiffness, to reduce cardiovascular disease (CVD) risk and to highlight potential mechanisms of action by which curcumin may improve arte...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fleenor BS,Carlini NA,Campbell MS

更新日期：2019-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances in our understanding of mammalian erythritol metabolism and its use as a predictive biomarker of cardiometabolic disease risk. RECENT FINDINGS:Elevated serum erythritol predicts future central adiposity gain and type 2 diabetes mellitus in healthy adults. Erythritol is a ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ortiz SR,Field MS

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Booth SL

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The intake of water and electrolytes is inseparable from the ingestion of nutrients by normal or artificial means. Recent reports have agreed in criticizing the poor standards of practice and of training in the management of fluid and electrolyte balance, resulting in a large amount of avoidable morbi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Allison SP,Lobo DN

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review summarizes recent evolutions in knowledge and discusses the concept of whom and when parenteral nutrition should be considered in critically ill patients as a total form of nutrition, in a supplemental form, or never. RECENT FINDINGS:Recent developments in our understanding of the ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ridley EJ

更新日期：2020-12-10 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease is exceptionally prevalent in patients with diabetes mellitus, which is an emerging pandemic. Unfortunately, the pathogenesis of diabetic myocardial disease is still poorly understood. RECENT FINDINGS:Evidence has emerged that perturbed cardiac energy metabolism (excessive depe...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Finck BN

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The high sugar content of regular soft drinks brought up discussions on their influence on energy balance and body weight especially in childhood and adolescence. This review examines the evidence for a causal relationship between soft drink consumption and excess weight gain in childhood and identifi...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Libuda L,Kersting M

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article is intended to briefly overview available methodological approaches for the study of regional metabolism in man in vivo, and to summarize recent advances in this field of research. RECENT FINDINGS:Several methods have been developed and currently allow for the qualitative and quantitativ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Magkos F,Sidossis LS

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:There is considerable interest in glutamine and selenium in critical care as both offer the potential to enhance host defences, through different but complimentary mechanisms and may reduce subsequent infections and mortality. The SIGNET trial (randomized controlled factorial trial) is the largest, cr...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Andrews PJ

更新日期：2010-03-01 00:00:00

abstract：:Critical illness and severe injury induce a number of neuroendocrine changes that initially enhance survival. However, for skeletal muscle, the hormonal environment is such that accelerated catabolism predominates. The prevailing hypercortisolemia is exacerbated by a resistance to or decreased production of anabolic h...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle is gaining increased attention as an endocrine organ. Recently, novel myokines and new effects of already established myokines have been identified. The objective of this review is to give an update on the recent advances in the field. RECENT FINDINGS:Several hundred putative myokines...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Karstoft K,Pedersen BK

更新日期：2016-07-01 00:00:00

abstract：:Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Castellino P,Cataliotti A

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steato hepatitis have an increasing prevalence among liver diseases. Overweight and obesity are frequently associated conditions in patients with fatty liver. Skeletal muscle mass depletion may also coexist with chronic liver disease even in ob...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Merli M,Lattanzi B,Aprile F

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The inflammatory response is essential in the response to pathogens. TNF-alpha, IL-1 and IL-6 are key mediators of the response. They initiate metabolic changes to provide nutrients for the immune system, from host tissues. These changes include hyperlipidemia and increased gluconeogenesis. Insulin re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Grimble RF

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, the latest evidence on the influence of dietary protein and plasma amino acids in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) is discussed. RECENT FINDINGS:Increasing protein consumption during weight loss and maintenance may help reduce liver fat content. Conversely,...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tricò D,Biancalana E,Solini A

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Muscle protein synthesis (MPS) and muscle protein breakdown are simultaneous ongoing processes. Here, we examine evidence for how protein quality can affect exercise-induced muscle protein anabolism or protein balance (MPS minus muscle protein breakdown). Evidence is highlighted showing differences in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Tang JE,Phillips SM

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Early interventional trials reported improvements in cardiac and exercise outcomes with inorganic nitrate ingestion. The current review aims to provide a brief update of recent evidence regarding ergogenic and cardiovascular effects of dietary nitrate and practical recommendations. RECENT FINDINGS:Re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kerley CP

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The review summarizes current knowledge and recent findings about how to practically apply medication in patients with dysphagia and how swallowing function may be positively or negatively affected by drugs. RECENT FINDINGS:Oropharyngeal dysphagia is a major health problem in older persons and was re...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wirth R,Dziewas R

更新日期：2019-01-01 00:00:00

abstract：:The K vitamins, a group of napthoquinones, are required for the carboxylation of a limited number of proteins including the bone matrix protein osteocalcin. Vitamin K1 (phylloquinone) and vitamin K2 (menaquinones), differ regarding food source (green vegetables and fermented products, respectively), bioavailability an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zittermann A

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular endothelial cells control vascular smooth muscle tone via the release of nitric oxide. Following adverse circulatory conditions, namely trauma and hemorrhage, endothelial cell dysfunction occurs, leading to a decrease in the release of endothelium-derived nitric oxide, which contributes to fu...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Loehe F,Bruns CJ,Nitsch SM,Angele MK

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide clinical investigators with an understanding of factors to consider when wishing to add cytokine and inflammatory marker measurements to their studies. RECENT FINDINGS:Inflammation involves complex and coordinated responses of the immune system to tissue damage. In the absence of tools to ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zhou X,Fragala MS,McElhaney JE,Kuchel GA

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an objective and comprehensive review of the recent literature addressing the effects of sex on protein metabolism. We also evaluate whether these differences can be attributed to physiology or methodology. Because of the developmental changes in hormonal milieu and body composition that oc...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Markofski MM,Volpi E

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Intradialytic nutritional support has been used for more than 30 years both in critically ill patients with acute renal failure and during maintenance hemodialysis. Present knowledge allows better estimation of its metabolic and nutritional efficacy, as well its effect on patient outcome. RECENT FIND...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cano NJ,Leverve XM

更新日期：2008-03-01 00:00:00

abstract：:The majority of the resting energy expenditure can be explained by the energy needs of a few highly metabolic organs, making up a small percentage of the body by weight. The relationship of the specific size, individual metabolism, and proportional contribution to the actual body weight and total energy expenditure fo...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： McClave SA,Snider HL

更新日期：2001-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to highlight recent research findings that advance our understanding of the relation between iron status and neural functioning. RECENT FINDINGS:Recent findings have helped to answer questions pertaining to the interrelationship of iron and neural functioning in three pri...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Murray-Kolb LE

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease. RECENT FINDINGS:Cancer cachexia is a severely debilitating and life-threate...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Muscaritoli M,Bossola M,Bellantone R,Rossi Fanelli F

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent advances in metabolomic tools now permit to characterize dysregulated metabolic pathways in various diseases associated with the identification of sensitive and specific early responding biomarkers that are critical both for the diagnosis of the type of insult as well as for the selection and e...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sébédio JL,Pujos-Guillot E,Ferrara M

更新日期：2009-07-01 00:00:00