Abstract:
PURPOSE OF REVIEW:The current review summarizes recent evolutions in knowledge and discusses the concept of whom and when parenteral nutrition should be considered in critically ill patients as a total form of nutrition, in a supplemental form, or never. RECENT FINDINGS:Recent developments in our understanding of the application of parenteral nutrition in critical care include the phases of illness, avoidance of overfeeding and the population in whom parenteral nutrition may be appropriate for. Importantly, one of the greatest lessons of recent times may be who not to provide parenteral nutrition to; however, a blanket approach of increased risk with parenteral nutrition is too simple for the modern context. SUMMARY:When providing total or supplemental parenteral nutrition, avoidance of overfeeding with total calories and/or glucose alone is critical, as is consideration to the phase of illness the patient is in, the population in whom it is to be applied, premorbid nutrition status and the setting (including adequacy of line management and expertise in parenteral nutrition provision). The appropriateness of parenteral nutrition should be considered in those where death is imminent or who are well nourished, likely to commence oral and/or enteral nutrition imminently and have a short-stay in intensive care, or are in a high-risk setting.
journal_name
Curr Opin Clin Nutr Metab Carejournal_title
Current opinion in clinical nutrition and metabolic careauthors
Ridley EJdoi
10.1097/MCO.0000000000000719subject
Has Abstractpub_date
2020-12-10 00:00:00eissn
1363-1950issn
1473-6519pub_type
杂志文章abstract:PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章
doi:10.1097/MCO.0000000000000721
更新日期:2020-12-05 00:00:00
abstract:PURPOSE OF REVIEW:Dietary fiber may play a role in obesity prevention through reduction of body weight and control of appetite, however, not all fibers are created equally, and characteristics of fiber such as viscosity, fermentability and solubility may affect appetite differently. RECENT FINDINGS:Although early stud...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000502
更新日期:2018-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Poor vitamin K nutrition has recently been linked to several chronic diseases associated with abnormal calcification, which affect many elderly. To understand the impact of vitamin K nutrition on healthy aging it is necessary to assess both the determinants and the adequacy of vitamin K nutritional st...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e328011ab5f
更新日期:2007-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Preventing unintentional weight and muscle loss is of crucial importance to maintain the condition and well-being of patients with cancer, improve treatment response and tolerance, and prolong survival. Anabolic resistance might explain why some cancer patients do not respond to nutritional interventi...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000236
更新日期:2016-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Glutamine and arginine are conditionally essential amino acids because depletion occurs in stressed conditions. Intravenous glutamine supplementation reduces morbidity and mortality in critically ill patients fed parenterally. In surgical patients, arginine-enriched diets have beneficial effects, but ...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e328333c27f
更新日期:2010-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This review focuses upon the biology and metabolism of a trace component in foods called nicotinamide riboside. Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitam...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32836510c0
更新日期:2013-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000346
更新日期:2017-03-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss transcriptional mechanisms regulating hepatic lipid metabolism. RECENT FINDINGS:Humans who are obese or have diabetes (NIDDM) or metabolic syndrome (MetS) have low blood and tissue levels of C20-22 polyunsaturated fatty acids (PUFAs). Although the impact of low C20-22 PUFAs on disease prog...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e328342991c
更新日期:2011-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Malnutrition and polypharmacy increase with age and polymorbidity and their relationship is based on a number of mechanisms. The occurrence of malnutrition in both in-patients and out-patients and its dependence on polymorbidity and age are well known, but the interrelation of polypharmacy and malnutr...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32835b612e
更新日期:2013-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews recent epidemiologic and intervention studies addressing the impact of hyperglycemia on morbidity and mortality in critically ill patients. It also discusses a growing body of literature examining why elevated blood glucose occurs in hospitalized patients without previously recogn...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e3281a3bf0a
更新日期:2007-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with a high prevalence of extrapulmonary manifestations and, frequently, cardiovascular comorbidity. Resveratrol is a food-derived compound with anti-inflammatory, antioxidant, metabolic and cardioprotective potential. Therefor...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000444
更新日期:2018-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to provide a concise overview of the polyphenol curcumin for improving arterial health, specifically endothelial function and arterial stiffness, to reduce cardiovascular disease (CVD) risk and to highlight potential mechanisms of action by which curcumin may improve arte...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000598
更新日期:2019-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the recent findings on metabolic monitoring and possible beneficial effects of an adequate nutrition therapy, based on indirect calorimetry as the golden standard to predict energy expenditure. RECENT FINDINGS:in the last decades, major steps are taken in the field of metabolism and nutriti...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000452
更新日期:2018-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Obese individuals have impaired respiratory function relative to their normal-weight counterparts. Despite these negative effects, obesity is paradoxically associated with better survival in individuals with chronic obstructive pulmonary disease (COPD). The purpose of this review is to describe this '...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32833e3453
更新日期:2010-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To examine the stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition admixtures in order to provide well tolerated and effective therapy. RECENT FINDINGS:Many stability investigations were carried out before 2005, but no critical appraisal of published data has been...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e3280ebb427
更新日期:2007-05-01 00:00:00
abstract::Arginine is a non-essential amino acid in mammals as judged from nitrogen balance study. Citrulline is synthesized from glutamate in the small intestine, whilst kidneys and some other tissues convert citrulline to arginine. Ornithine transcarbamylase and carbamylphosphate synthetase are expressed in liver and small in...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-199807000-00004
更新日期:1998-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The present review provides an overview of the different dietary quality indices in use. In the first decades, most indices were developed for the general adult population and were based on the American dietary guidelines and the Mediterranean diet. This review focuses on new, other dietary quality in...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32830a49db
更新日期:2008-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The intake of water and electrolytes is inseparable from the ingestion of nutrients by normal or artificial means. Recent reports have agreed in criticizing the poor standards of practice and of training in the management of fluid and electrolyte balance, resulting in a large amount of avoidable morbi...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200401000-00006
更新日期:2004-01-01 00:00:00
abstract::The most common methods for measuring the incorporation of tracer amino acids into tissue protein are the constant tracer infusion and the flooding dose. The flooding dose is an attractive method for measuring tissue protein synthesis because of its convenience and precision. A primary assumption of the method, that t...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200101000-00010
更新日期:2001-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To examine the results of new investigations that look at the efficacy of nutrient/training strategies on metabolism and athletic performance. RECENT FINDINGS:'Dietary periodization' involves the manipulation of macronutrient intake in association with changes in physical training. Such interventions...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/01.mco.0000232911.69236.3b
更新日期:2006-07-01 00:00:00
abstract::Lipophilic molecules can passively diffuse across cell membranes, a process that is driven by the concentration gradient, by availability of acceptors to facilitate desorption from the bilayer, and by cellular metabolism. However, evidence has accumulated that supports the existence of specialized, protein-facilitated...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200007000-00003
更新日期:2000-07-01 00:00:00
abstract::Studies of many different rodent models of muscle wasting have indicated that accelerated proteolysis via the ubiquitin-proteasome pathway is the principal cause of muscle atrophy induced by fasting, cancer cachexia, metabolic acidosis, denervation, disuse, diabetes, sepsis, burns, hyperthyroidism and excess glucocort...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200105000-00003
更新日期:2001-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of the present review is to provide insights into the future therapeutic approaches to cancer-related muscle wasting that flow from the progressive knowledge of mechanisms regulating muscle mass in health and disease. RECENT FINDINGS:Cancer cachexia is a severely debilitating and life-threate...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/01.mco.0000134366.07148.2e
更新日期:2004-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This article provides an overview of the most recent molecular and clinical outcomes of studies that investigate the effect of weight loss and calorie restriction on carbohydrate metabolism, obtained either by dieting or bariatric surgery. It will focus on aspects of carbohydrate metabolism related to...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/01.mco.0000172585.09762.8e
更新日期:2005-07-01 00:00:00
abstract::Acute and chronic diseases are frequently characterized by alterations in energy metabolism that influence nutritional requirements and clinical care. Knowledge of the effect of disease on daily energy expenditure and its components is fundamental to understanding the impact of the disease process on energy balance. T...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200109000-00009
更新日期:2001-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The inflammatory response is essential in the response to pathogens. TNF-alpha, IL-1 and IL-6 are key mediators of the response. They initiate metabolic changes to provide nutrients for the immune system, from host tissues. These changes include hyperlipidemia and increased gluconeogenesis. Insulin re...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200209000-00015
更新日期:2002-09-01 00:00:00
abstract::Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/00075197-200201000-00010
更新日期:2002-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Sarcopenia is a progressive generalized decline in skeletal muscle mass, strength, and function. This condition is highly prevalent in critically ill patients and is associated with poor outcomes in the ICU. In this review, we describe the use, evidence, and limitations of the most common validated im...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章
doi:10.1097/MCO.0000000000000673
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:A large percentage of older adults do not receive recommended amounts of many nutrients from food alone. Accordingly, the routine use of dietary supplements has become common among older persons. Although supplement use provides potential benefits by increasing nutrient intakes, there are potential dr...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0000000000000512
更新日期:2018-11-01 00:00:00
abstract:PURPOSE OF REVIEW:There is considerable interest in glutamine and selenium in critical care as both offer the potential to enhance host defences, through different but complimentary mechanisms and may reduce subsequent infections and mortality. The SIGNET trial (randomized controlled factorial trial) is the largest, cr...
journal_title:Current opinion in clinical nutrition and metabolic care
pub_type: 杂志文章,评审
doi:10.1097/MCO.0b013e32833617cd
更新日期:2010-03-01 00:00:00