Polypharmacy and malnutrition.

Abstract:

PURPOSE OF REVIEW:Malnutrition and polypharmacy increase with age and polymorbidity and their relationship is based on a number of mechanisms. The occurrence of malnutrition in both in-patients and out-patients and its dependence on polymorbidity and age are well known, but the interrelation of polypharmacy and malnutrition has been far less investigated. The countries with the highest occurrence of polypharmacy in Europe include the Czech Republic and Finland, whereas the lowest prevalence of polypharmacy is found in Norway and the Netherlands. RECENT FINDINGS:The occurrence, consequences and mutual relationship of malnutrition and polypharmacy are described. Up-to-date knowledge regarding the influence of drugs on nutritional status is summarized. SUMMARY:The effect of polypharmacy on nutrition is suggested from the observations that problems with nutrition occur mostly in elderly patients, and that such patients are more frequently subject to polypharmacy. It is known that about 65% of hospitalized patients have a worse nutritional status than their healthy contemporaries. A worsened nutritional status may adversely influence the process of treatment.

authors

Zadak Z,Hyspler R,Ticha A,Vlcek J

doi

10.1097/MCO.0b013e32835b612e

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

50-5

issue

1

eissn

1363-1950

issn

1473-6519

journal_volume

16

pub_type

杂志文章,评审
  • Nutrition in alcoholic steatohepatitis: more of the same or something new?

    abstract:PURPOSE OF REVIEW:To describe the evidences for and against the different nutritional and nonnutritional therapeutic approaches for severe alcoholic steatohepatitis, based on data from randomized controlled trials, in order to answer the question posed in the title: 'more of the same or something new?'. RECENT FINDING...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32830b5d1e

    authors: Cabré E

    更新日期:2008-09-01 00:00:00

  • Nutritional and metabolic advances in inflammatory bowel disease.

    abstract::Crude measurements of nutritional status, such as body weight, are inadequate to assess the severity and consequence of malnutrition among inflammatory bowel disease patients. Functional deficiency resulting in osteopenia and muscle weakness have been demonstrated in these patients when compared to controls. Manipulat...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199809000-00002

    authors: Burke A,Lichtenstein GR,Rombeau JL

    更新日期:1998-09-01 00:00:00

  • Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes.

    abstract:PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32833aab7f

    authors: Sell H,Eckel J

    更新日期:2010-07-01 00:00:00

  • Assessment of muscle mass in critically ill patients: role of the sarcopenia index and images studies.

    abstract:PURPOSE OF REVIEW:Sarcopenia is a progressive generalized decline in skeletal muscle mass, strength, and function. This condition is highly prevalent in critically ill patients and is associated with poor outcomes in the ICU. In this review, we describe the use, evidence, and limitations of the most common validated im...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章

    doi:10.1097/MCO.0000000000000673

    authors: Lopez-Ruiz A,Kashani K

    更新日期:2020-09-01 00:00:00

  • Soft drinks and body weight development in childhood: is there a relationship?

    abstract:PURPOSE OF REVIEW:The high sugar content of regular soft drinks brought up discussions on their influence on energy balance and body weight especially in childhood and adolescence. This review examines the evidence for a causal relationship between soft drink consumption and excess weight gain in childhood and identifi...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32833189f6

    authors: Libuda L,Kersting M

    更新日期:2009-11-01 00:00:00

  • Diet of lactating women and allergic reactions in their infants.

    abstract:PURPOSE OF REVIEW:To evaluate whether the diet of lactating women modulates the development of allergic disease in their children. RECENT FINDINGS:Although maternal avoidance of common food protein allergens was previously recommended for lactating women with infants predisposed to allergic disease, recent expert revi...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/01.mco.0000222113.46042.50

    authors: Palmer DJ,Makrides M

    更新日期:2006-05-01 00:00:00

  • Conceptual and methodological issues relevant to cytokine and inflammatory marker measurements in clinical research.

    abstract:PURPOSE OF REVIEW:To provide clinical investigators with an understanding of factors to consider when wishing to add cytokine and inflammatory marker measurements to their studies. RECENT FINDINGS:Inflammation involves complex and coordinated responses of the immune system to tissue damage. In the absence of tools to ...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32833cf3bc

    authors: Zhou X,Fragala MS,McElhaney JE,Kuchel GA

    更新日期:2010-09-01 00:00:00

  • Anabolic hormones in critically ill patients.

    abstract::Critical illness and severe injury induce a number of neuroendocrine changes that initially enhance survival. However, for skeletal muscle, the hormonal environment is such that accelerated catabolism predominates. The prevailing hypercortisolemia is exacerbated by a resistance to or decreased production of anabolic h...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199903000-00014

    authors: Ferrando AA

    更新日期:1999-03-01 00:00:00

  • Nutrition support in patients with multiple organ failure.

    abstract::The problem with any attempt to feed patients in multiple organ failure is that, because of an ongoing inflammatory process, the conventional techniques of supplying energy and protein do not maintain lean tissue mass. In addition, the conventional markers of nutritional status, both anthropometric (body mass and comp...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-199803000-00012

    authors: Campbell IT

    更新日期:1998-03-01 00:00:00

  • Brown fat fuel use and regulation of energy homeostasis.

    abstract:PURPOSE OF REVIEW:New evidence has recently supported the notion that brown adipose tissue (BAT) is present in adult humans and can play a prominent role in the regulation of body weight and metabolism. This has renewed the efforts to understand the physiologic mechanisms by which BAT is activated, which in turn could ...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000063

    authors: Loyd C,Obici S

    更新日期:2014-07-01 00:00:00

  • The low FODMAP diet: fundamental therapy in the management of irritable bowel syndrome.

    abstract:PURPOSE OF REVIEW:The low FODMAP diet is now recognized as first-line therapy for treatment of irritable bowel syndrome (IBS) symptoms including abdominal pain, gas, bloating, diarrhea and or constipation. This information must be disseminated for application to clinical practice. RECENT FINDINGS:There are many people...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000398

    authors: Ireton-Jones C

    更新日期:2017-09-01 00:00:00

  • Update on lipid species and paediatric nonalcoholic fatty liver disease.

    abstract:PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000346

    authors: Mann JP,Feldstein AE,Nobili V

    更新日期:2017-03-01 00:00:00

  • The role of probiotics in gastrointestinal surgery.

    abstract:PURPOSE OF REVIEW:Postoperative complications in gastrointestinal elective surgery have been described as low. In certain circumstances, however, such as those including high-risk patients, the incidence is higher. In such situations, bacteremia and infectious complications may be caused by translocation of either gast...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/01.mco.0000241674.55417.c9

    authors: Correia MI,Nicoli JR

    更新日期:2006-09-01 00:00:00

  • Vitamin K: dietary intake and requirements in different clinical conditions.

    abstract:PURPOSE OF REVIEW:Vitamin K is an enzyme cofactor for the carboxylation of vitamin K-dependent proteins. Functions include coagulation and regulation of calcification. Different clinical conditions may alter vitamin K requirements by affecting vitamin K status and vitamin K-dependent proteins carboxylation that are rev...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000112

    authors: Harshman SG,Saltzman E,Booth SL

    更新日期:2014-11-01 00:00:00

  • Neural systems controlling food intake and energy balance in the modern world.

    abstract:PURPOSE OF REVIEW:Obesity continues to increase around the globe, and creates a major health problem because of its comorbidities such as diabetes and cardiovascular disease. Considering that the major cause of most human obesities is the modern lifestyle in a rapidly changing environment, this suggests that the battle...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200311000-00002

    authors: Berthoud HR

    更新日期:2003-11-01 00:00:00

  • New lipids in enteral feeding.

    abstract:PURPOSE OF REVIEW:Lipid sources for enteral nutrition continue to be an exciting area of investigation. It is timely to review recent developments which have largely contributed to thrust enteral feeding into a new era. RECENT FINDINGS:Although much more research needs to be done, there is a better understanding of th...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200403000-00003

    authors: Roy CC,Bouthillier L,Seidman E,Levy E

    更新日期:2004-03-01 00:00:00

  • Synergy of genes and nutrients: the case of homocysteine.

    abstract:PURPOSE OF REVIEW:Folic acid is now considered an important functional food component: it lowers potentially toxic homocysteine, prevents birth defects and modulates the risk of several cancers. The complexity of interactions involved, however, means we still have much to learn about the role of folate and homocysteine...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/01.mco.0000247468.18790.1e

    authors: Lucock MD

    更新日期:2006-11-01 00:00:00

  • Berries, their micronutrients and bone health.

    abstract:PURPOSE OF REVIEW:The design and the development of functional foods is a key issue for bone health and a scientific challenge as well. As most studies have focused on calcium, and have paid less attention to other nutrients, our knowledge of the influence of nutrition on bone health remains limited. It has been well a...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000324

    authors: Davicco MJ,Wittrant Y,Coxam V

    更新日期:2016-11-01 00:00:00

  • Fatty acid regulation of hepatic lipid metabolism.

    abstract:PURPOSE OF REVIEW:To discuss transcriptional mechanisms regulating hepatic lipid metabolism. RECENT FINDINGS:Humans who are obese or have diabetes (NIDDM) or metabolic syndrome (MetS) have low blood and tissue levels of C20-22 polyunsaturated fatty acids (PUFAs). Although the impact of low C20-22 PUFAs on disease prog...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e328342991c

    authors: Jump DB

    更新日期:2011-03-01 00:00:00

  • Fructose malabsorption syndrome.

    abstract:PURPOSE OF REVIEW:Fructose malabsorption is associated with gastrointestinal symptoms. This review examines new findings on the physiology, assessment and therapy of fructose malabsorption in functional gastrointestinal disorders. RECENT FINDINGS:Additional GLUT transport mechanisms that regulate fructose absorption m...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e328361c556

    authors: Putkonen L,Yao CK,Gibson PR

    更新日期:2013-07-01 00:00:00

  • Causes and consequences of hyperglycemia in critical illness.

    abstract:PURPOSE OF REVIEW:This article reviews recent epidemiologic and intervention studies addressing the impact of hyperglycemia on morbidity and mortality in critically ill patients. It also discusses a growing body of literature examining why elevated blood glucose occurs in hospitalized patients without previously recogn...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e3281a3bf0a

    authors: Falciglia M

    更新日期:2007-07-01 00:00:00

  • Are prospective cohort studies an appropriate tool to answer clinical nutrition questions?

    abstract:PURPOSE OF REVIEW:Randomized controlled trials can be difficult to conduct in critically ill patients and may not always be the most appropriate type of study. Cohort studies can provide valuable information in large complete populations of patients without strict exclusion criteria and without the need for informed co...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32835d803e

    authors: Vincent JL,Preiser JC

    更新日期:2013-03-01 00:00:00

  • Metabolomics in evaluation of glucose disorders.

    abstract:PURPOSE OF REVIEW:Recent advances in metabolomic tools now permit to characterize dysregulated metabolic pathways in various diseases associated with the identification of sensitive and specific early responding biomarkers that are critical both for the diagnosis of the type of insult as well as for the selection and e...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32832c97c3

    authors: Sébédio JL,Pujos-Guillot E,Ferrara M

    更新日期:2009-07-01 00:00:00

  • Modifying diet and physical activity to support pregnant women who are overweight or obese.

    abstract:PURPOSE OF REVIEW:Overweight and obesity represent a significant health burden during pregnancy, placing women and their infants at increased risk of adverse health outcomes. Although there is considerable observational literature describing the effect of gestational weight gain in pregnancy, research efforts have focu...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000170

    authors: Dodd JM,O'Brien CM,Grivell RM

    更新日期:2015-05-01 00:00:00

  • Nutritional issues in irritable bowel syndrome.

    abstract::Food products have variously been reported as causing, perpetuating or treating irritable bowel syndrome. The evidence for this is reviewed with regard to recent studies investigating symptom reporting, mono- and disaccharide malabsorption and probiotics. The development of objective measures remains an urgent priorit...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200111000-00013

    authors: Dunlop SP,Spiller RC

    更新日期:2001-11-01 00:00:00

  • Changes of protein kinetics in nephrotic patients.

    abstract::Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200201000-00010

    authors: Castellino P,Cataliotti A

    更新日期:2002-01-01 00:00:00

  • The acute and long-term effects of dietary fatty acids on vascular function in health and disease.

    abstract:PURPOSE OF REVIEW:Vascular function is recognized as an early and integrative marker of cardiovascular disease. While there is consistent evidence that the quantity of dietary fat has significant effects on vascular function, the differential effects of individual fatty acids is less clear. This review summarizes recen...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e32835c5f29

    authors: Lovegrove JA,Griffin BA

    更新日期:2013-03-01 00:00:00

  • Can it all be done by enteral nutrition?

    abstract:PURPOSE OF REVIEW:During recent years techniques and metabolic considerations have been discussed intensively. One contributing reason is that results have not always been easy to interpret and introduce into clinical practice. Nutrition through the enteral and parenteral route has classically been compared, and this i...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/00075197-200403000-00013

    authors: Hammarqvist F

    更新日期:2004-03-01 00:00:00

  • Lipid metabolism in critical illness.

    abstract:PURPOSE OF REVIEW:This article describes recent findings regarding lipid metabolism in critical illness as well as in lipid therapy. RECENT FINDINGS:In critical illness, in the presence of a decrease in lipid absorption, adipose tissue lipolysis raises triglyceride levels. High-density lipoprotein and low-density lipo...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0000000000000253

    authors: Green P,Theilla M,Singer P

    更新日期:2016-03-01 00:00:00

  • Stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition mixtures.

    abstract:PURPOSE OF REVIEW:To examine the stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition admixtures in order to provide well tolerated and effective therapy. RECENT FINDINGS:Many stability investigations were carried out before 2005, but no critical appraisal of published data has been...

    journal_title:Current opinion in clinical nutrition and metabolic care

    pub_type: 杂志文章,评审

    doi:10.1097/MCO.0b013e3280ebb427

    authors: Puzovic M,Hardy G

    更新日期:2007-05-01 00:00:00