Protein and physical activity in older persons.

abstract：PURPOSE OF REVIEW:Here, we discuss recent work focused on the role of activating transcription factor 4 (ATF4) in skeletal muscle atrophy. RECENT FINDINGS:Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression; however, the transcriptional regulatory proteins responsible for those c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Adams CM,Ebert SM,Dyle MC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Lipid sources for enteral nutrition continue to be an exciting area of investigation. It is timely to review recent developments which have largely contributed to thrust enteral feeding into a new era. RECENT FINDINGS:Although much more research needs to be done, there is a better understanding of th...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Roy CC,Bouthillier L,Seidman E,Levy E

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a concise overview of the polyphenol curcumin for improving arterial health, specifically endothelial function and arterial stiffness, to reduce cardiovascular disease (CVD) risk and to highlight potential mechanisms of action by which curcumin may improve arte...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fleenor BS,Carlini NA,Campbell MS

更新日期：2019-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Recently, the US Food and Drug Administration and the European Medicines Agency approved the glucagon-like peptide 2 analogue, teduglutide, for the treatment of short bowel syndrome (SBS), and this review describes the physiological basis for its clinical use. RECENT FINDINGS:By affecting the intesti...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Jeppesen PB

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:New evidence has recently supported the notion that brown adipose tissue (BAT) is present in adult humans and can play a prominent role in the regulation of body weight and metabolism. This has renewed the efforts to understand the physiologic mechanisms by which BAT is activated, which in turn could ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Loyd C,Obici S

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Epigenetics has emerged in recent years as one of the most important biological mechanisms linking exposures across the life course to long-term health. This article reviews recent developments in our understanding of the metabolic and genetic determinants of epigenetic variation in human populations....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Haggarty P

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review provides an overview of the different dietary quality indices in use. In the first decades, most indices were developed for the general adult population and were based on the American dietary guidelines and the Mediterranean diet. This review focuses on new, other dietary quality in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fransen HP,Ocké MC

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses upon the biology and metabolism of a trace component in foods called nicotinamide riboside. Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitam...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chi Y,Sauve AA

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Investigations into the regulation of muscle protein synthesis (MPS) are a cornerstone of understanding the control of muscle mass. Rates of MPS are finely tuned according to levels of activity, nutrient availability and health status. For instance, rates of MPS are positively regulated by exercise an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Phillips BE,Hill DS,Atherton PJ

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the recent advances in our understanding of fatty acids and lipids in paediatric nonalcoholic fatty liver disease (NAFLD) and their future implications. RECENT FINDINGS:Data have been accumulated to suggest that ceramides are the main drivers of hepatic insulin resistance in NAFLD, and in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mann JP,Feldstein AE,Nobili V

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The gastrointestinal tract plays an important role in the maintenance of fluid and electrolyte balance, and its diseases cause disturbances in that balance. Conversely, fluid and electrolyte disorders may disturb gastrointestinal function. The purpose of this review is to highlight some recent literat...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Macafee DA,Allison SP,Lobo DN

更新日期：2005-03-01 00:00:00

abstract：:Arginine is a non-essential amino acid in mammals as judged from nitrogen balance study. Citrulline is synthesized from glutamate in the small intestine, whilst kidneys and some other tissues convert citrulline to arginine. Ornithine transcarbamylase and carbamylphosphate synthetase are expressed in liver and small in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wakabayashi Y

更新日期：1998-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease (NAFLD) is the liver epidemic of our time. Diet strongly influences its development and should be a component of any treatment plan. It is crucial to standardize diet recommendations in an evidence-based manner. RECENT FINDINGS:Calorie restriction per se seems benefic...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Carvalhana S,Machado MV,Cortez-Pinto H

更新日期：2012-09-01 00:00:00

abstract：:Critical illness and severe injury induce a number of neuroendocrine changes that initially enhance survival. However, for skeletal muscle, the hormonal environment is such that accelerated catabolism predominates. The prevailing hypercortisolemia is exacerbated by a resistance to or decreased production of anabolic h...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Autophagy is an evolutionarily conserved cellular programme for the turnover of organelles, proteins, and other macromolecules, involving the lysosomal degradation pathway. Emerging evidence suggests that autophagy can play a central role in human metabolism as well as impact diverse cellular processe...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ryter SW,Koo JK,Choi AM

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The term oxidative stress is often used to indicate a condition in which the accumulation of reactive oxygen species is considered just damaging. We will discuss both the physiological and pathological role of oxidative stress on skeletal muscle homeostasis and function, and how oxidative stress can a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Musarò A,Fulle S,Fanò G

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The increase in obesity in developed societies drives interest in the interplay of energy intake, metabolic energy expenditure, and body energy stores. A better understanding of energy management in physically active and undernourished humans should help guide strategies to manage obesity safely and e...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Hoyt RW,Friedl KE

更新日期：2006-11-01 00:00:00

abstract：:New results on the physiological properties of conjugated linoleic acid have been published by several working groups, especially showing the effects of single conjugated linoleic acid isomers on carcinogenesis and body composition. Recently, other studies have shown that conjugated linoleic acid has an influence on d...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sébédio JL,Gnaedig S,Chardigny JM

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Intradialytic nutritional support has been used for more than 30 years both in critically ill patients with acute renal failure and during maintenance hemodialysis. Present knowledge allows better estimation of its metabolic and nutritional efficacy, as well its effect on patient outcome. RECENT FIND...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Cano NJ,Leverve XM

更新日期：2008-03-01 00:00:00

abstract：:Laboratory methods for the measurement of micronutrients are usually based upon determinations in the peripheral blood. Most are relatively insensitive, but can screen for impending acute deficiency or toxicity. The metabolic responses to disease, injury and infection may alter the laboratory findings independently of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fell GS,Talwar D

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The mortality and morbidity associated with severe acute malnutrition (SAM) remain high. A summary of recent studies that are of interest to clinicians treating children with SAM is provided. RECENT FINDINGS:Three important themes emerged in 2015: the use of anthropometry in the diagnosis of SAM and ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Nel ED

更新日期：2016-05-01 00:00:00

abstract：:Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. The rate of hepatic absolute and fractional albumin synthesis are increased. Transferrin synthesis is also increased. Fibrinogen levels are elevated in nephrotic syndrome because of a...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Castellino P,Cataliotti A

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Until relatively recently, the only significant source of lactoferrin in the diet was human lactoferrin, provided in breast milk. Today, however, bovine lactoferrin, isolated by dairy technology, as well as recombinant human lactoferrin are commercially available and can be added to foods and clinical...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lönnerdal B

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults. RECENT FINDINGS:The incidence of gastrointestinal complications in critically ill patients published in the literature is...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： López-Herce J

更新日期：2009-03-01 00:00:00

abstract：:This review examines recent advances in the dietary modulation of gene expression in the gastrointestinal tract. We have chosen to concentrate on individual genes and examine what is known about their regulation, attempting to link different studies together. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kelly EJ,Sanderson IR

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine the stability and compatibility of histamine H2-receptor antagonists in parenteral nutrition admixtures in order to provide well tolerated and effective therapy. RECENT FINDINGS:Many stability investigations were carried out before 2005, but no critical appraisal of published data has been...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Puzovic M,Hardy G

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is associated with low-grade chronic inflammation in adipose tissue. This review presents an update on human and rodent studies analyzing the nature of fat-infiltrating immune cells, the time course of adipose tissue infiltration and underlying mechanisms. RECENT FINDINGS:Intensive studies in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sell H,Eckel J

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle is gaining increased attention as an endocrine organ. Recently, novel myokines and new effects of already established myokines have been identified. The objective of this review is to give an update on the recent advances in the field. RECENT FINDINGS:Several hundred putative myokines...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Karstoft K,Pedersen BK

更新日期：2016-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity continues to increase around the globe, and creates a major health problem because of its comorbidities such as diabetes and cardiovascular disease. Considering that the major cause of most human obesities is the modern lifestyle in a rapidly changing environment, this suggests that the battle...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Berthoud HR

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The data indicating that alcohol is an important factor increasing the risk to develop gastrointestinal cancer are consolidating. The purpose of this review is to summarize current evidence. RECENT FINDINGS:Acetaldehyde is the first metabolite of ethanol metabolism and has direct carcinogenic and mut...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Haas SL,Ye W,Löhr JM

更新日期：2012-09-01 00:00:00