Abstract:
:Liver involvement in amyloidosis is rarely associated with intrahepatic cholestasis. The cases recorded in the literature indicate that there is a tendency toward periportal deposition, leading to centrilobular cholestasis. Our case was most interesting in that the amyloid deposition was most severe in the centrilobular area. Presumably there was still sufficient compression of canaliculi at the periportal level to produce obstruction of the bile flow. This would appear to be a less common but distinct variant of systemic amyloidosis with associated obstructive jaundice.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Finkelstein SD,Fornasier VL,Pruzanski Wdoi
10.1016/s0046-8177(81)80029-9subject
Has Abstractpub_date
1981-05-01 00:00:00pages
470-2issue
5eissn
0046-8177issn
1532-8392pii
S0046-8177(81)80029-9journal_volume
12pub_type
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