The effective attenuation coefficient of soft tissue in the presence of Compton scattering from bone: experiments on models.

abstract：:There are a number of gel dosimeter calibration methods in contemporary usage. The present study is a detailed Monte Carlo investigation into the accuracy of several calibration techniques. Results show that for most arrangements the dose to gel accurately reflects the dose to water, with the most accurate method invo...

journal_title：Physics in medicine and biology

authors： Taylor ML,Franich RD,Johnston PN,Millar RM,Trapp JV

更新日期：2007-07-07 00:00:00

abstract：:In external beam radiation therapy, radioactive beams offer the best clinical solution to simultaneously treat and in vivo monitor the dose delivery and tumor response using PET or PET-CT imaging. However, difficulties mainly linked to the low production efficiency have so far limited their use. This study is devoted ...

journal_title：Physics in medicine and biology

authors： Lazzeroni M,Brahme A

更新日期：2011-03-21 00:00:00

abstract：:The x-ray exposure to patients has become a major concern in computed tomography (CT) and minimizing the radiation exposure has been one of the major efforts in the CT field. Due to plenty high-attenuation tissues in the human chest, under low-dose scan protocols, thoracic low-dose CT (LDCT) images tend to be severely...

journal_title：Physics in medicine and biology

authors： Chen Y,Yang Z,Hu Y,Yang G,Zhu Y,Li Y,Luo L,Chen W,Toumoulin C

更新日期：2012-05-07 00:00:00

abstract：:In this study, we evaluate the feasibility of designing a beveled fiber-optic probe coupled with a ball lens for improving depth-resolved fluorescence measurements of epithelial tissue using Monte Carlo (MC) simulations. The results show that by using the probe configuration with a beveled tip collection fiber and a f...

journal_title：Physics in medicine and biology

authors： Jaillon F,Zheng W,Huang Z

更新日期：2008-02-21 00:00:00

abstract：:Recent theoretical research on spatiobiologically integrated radiotherapy has focused on optimization models that adapt fluence-maps to the evolution of tumor state, for example, cell densities, as observed in quantitative functional images acquired over the treatment course. We propose an optimization model that adap...

journal_title：Physics in medicine and biology

authors： Ajdari A,Ghate A,Kim M

更新日期：2018-03-27 00:00:00

abstract：:The process of organ motion correction in scintigraphy is analysed in the frequency domain. The sequence of the chi- and gamma- coordinates registered during scintigraphic recording is converted to a frequency spectrum by a discrete Fourier transform. In the frequency domain motion correction is performed by linear fi...

journal_title：Physics in medicine and biology

authors： Schmidlin P

更新日期：1975-05-01 00:00:00

abstract：:This work presents a Monte Carlo model of Leksell Gamma Knife Perfexion as well as the main parameters of the dose distribution in the standard phantom obtained using this model. The model is developed in the Geant4 simulation toolkit in a modular way which enables its reuse in other Perfexion studies. Large phase spa...

journal_title：Physics in medicine and biology

authors： Pipek J,Novotný J,Novotný J,Kozubíková P

更新日期：2014-12-21 00:00:00

abstract：:The 50-year tenure of Physics in Medicine and Biology has coincided with some of the most important developments in radiological science, including the introduction of artificial radioactivity, computers and 3D imaging into medicine. These events have profoundly influenced the development of brachytherapy. Although it...

journal_title：Physics in medicine and biology

authors： Williamson JF

更新日期：2006-07-07 00:00:00

abstract：:Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Stankovic U,Sonke JJ,Keall PJ

更新日期：2017-06-07 00:00:00

abstract：:This study presents a new approach to accurately account for the medium-dependent effect in model-based dose calculations for kilovoltage (kV) x-rays. This approach is based on the hypothesis that the correction factors needed to convert dose from model-based dose calculations to absorbed dose-to-medium depend on both...

journal_title：Physics in medicine and biology

authors： Pawlowski JM,Ding GX

更新日期：2011-07-07 00:00:00

abstract：:During minimally invasive surgery (MIS) for lung tumor resection, the localization of tumors or nodules relies on visual inspection of the deflated lung on intra-procedural video. For patients with tumors or nodules located deeper in the lung, this localization is not possible without prior invasive marking techniques...

journal_title：Physics in medicine and biology

authors： Lesage AJ,Rajaram R,Tam AL,Rigaud BS,Brock KK,Rice DC,Cazoulat G

更新日期：2020-09-09 00:00:00

abstract：:Quantification of nuclear medicine image data is a prerequisite for personalized absorbed dose calculations and quantitative biodistribution studies. The spatial response of a detector is a governing factor affecting the accuracy of image quantification, and the aim of this work was to model this impact. To simulate s...

journal_title：Physics in medicine and biology

authors： Holstensson M,Partridge M,Buckley SE,Flux GD

更新日期：2010-03-21 00:00:00

abstract：:Gold nanoparticle (GNP) radio-enhancement is a promising technique to increase the dose deposition in a tumor while sparing neighboring healthy tissue. Previous experimental studies showed effects on cell survival and tumor control for keV x-rays but surprisingly also for MV-photons, proton and carbon-ion beams. In a ...

journal_title：Physics in medicine and biology

authors： Rudek B,McNamara A,Ramos-Méndez J,Byrne H,Kuncic Z,Schuemann J

更新日期：2019-08-28 00:00:00

abstract：:The sensitivity and detection limit for measurements of the concentration of cadmium in the kidney cortex of man in vivo have been investigated using the technique of X-ray fluorescence. An 11 GB1 241Am source was used to generate the characteristic K alpha X-rays of cadmium. The variation in the sensitivity for the d...

journal_title：Physics in medicine and biology

authors： Ahlgren L,Mattsson S

更新日期：1981-01-01 00:00:00

abstract：:Blood and blood products are irradiated with gamma rays to reduce the risk of graft versus host disease (GVHD). A simple technique using electron beams produced by a medical linear accelerator has been studied to evaluate irradiation of blood and blood products. Variations in applied doses for a single field 20 MeV el...

journal_title：Physics in medicine and biology

authors： Butson MJ,Cheung T,Yu PK,Stokes MJ

更新日期：2000-11-01 00:00:00

abstract：:The performance of a light sharing and recirculation mechanism that allows the extraction of depth of interaction (DOI) are investigated in this paper, with a particular focus on timing. In parallel, a method to optimize the coincidence time resolution (CTR) of PET detectors by use of the DOI information is proposed a...

journal_title：Physics in medicine and biology

authors： Pizzichemi M,Polesel A,Stringhini G,Gundacker S,Lecoq P,Tavernier S,Paganoni M,Auffray E

更新日期：2019-08-07 00:00:00

abstract：:A CT scanner has been constructed specifically to determine the three-dimensional distribution of bone mineral in the medullary cavities of the radius, ulna and femur. A source of x-rays (153Gd) and a multiwire proportional counter (MWPC) are mounted at opposite ends of a diameter of an annular mounting. The limb is p...

journal_title：Physics in medicine and biology

authors： Horsman A,Sutcliffe J,Burkinshaw L,Wild P,Skilling J,Webb S

更新日期：1987-10-01 00:00:00

abstract：:The aim of this study was to measure entrance skin doses on patients undergoing cone-beam computed tomography (CBCT) examinations, to establish conversion factors between skin and organ doses, and to estimate cancer risk from CBCT exposures. 266 patients (age 8-83) were included, involving three imaging centres. CBCT ...

journal_title：Physics in medicine and biology

authors： Pauwels R,Cockmartin L,Ivanauskaité D,Urbonienė A,Gavala S,Donta C,Tsiklakis K,Jacobs R,Bosmans H,Bogaerts R,Horner K,SEDENTEXCT Project Consortium.

更新日期：2014-07-21 00:00:00

abstract：:The purpose of this study was the evaluation of the impact of a variable relative biological effectiveness (RBE) compared to a constant RBE value of 1.1 in proton therapy prostate trials due to uncertainties in α/β ratio. Twenty patients receiving passive scattered proton therapy (PSPT) and fifteen patients receiving ...

journal_title：Physics in medicine and biology

authors： Marteinsdottir M,Paganetti H

更新日期：2019-06-05 00:00:00

abstract：:Registration of different imaging modalities such as CT, MRI, functional MRI (fMRI), positron (PET) and single photon (SPECT) emission tomography is used in many clinical applications. Determining the quality of any automatic registration procedure has been a challenging part because no gold standard is available to e...

journal_title：Physics in medicine and biology

authors： Ceylan C,van der Heide UA,Bol GH,Lagendijk JJ,Kotte AN

更新日期：2005-05-21 00:00:00

abstract：:We examine how the choice of CT x-ray beam filtration and phantom size influences patient dose (D) to computed tomography dose index (CTDI) conversion factors (i.e. D/CTDI). The ratio of head to body phantom CTDI(w) for a defined scan technique is alpha, and the ratio of organ dose when the body filter is changed to t...

journal_title：Physics in medicine and biology

authors： Huda W,Sterzik A,Tipnis S

更新日期：2010-01-21 00:00:00

abstract：:The present note addresses the development of a lung tumor position predictor to be used in dynamic tumor tracking radiotherapy, abbreviated as DTT-RT. As there exists 50-500 ms positioning lag in the control of the multi-leaf collimator (MLC) of commercial medical linear accelerators, prediction of future lung tumor ...

journal_title：Physics in medicine and biology

authors： Jiang K,Fujii F,Shiinoki T

更新日期：2019-10-31 00:00:00

abstract：:Dental tomographic cone-beam x-ray imaging devices record truncated projections and reconstruct a region of interest (ROI) inside the head. Image reconstruction from the resulting local tomography data is an ill-posed inverse problem. A new Bayesian multiresolution method is proposed for local tomography reconstructio...

journal_title：Physics in medicine and biology

authors： Niinimäki K,Siltanen S,Kolehmainen V

更新日期：2007-11-21 00:00:00

abstract：:A novel transmission detector (IBA Dosimetry, Germany) developed as an IMRT quality assurance tool, intended for in vivo patient dose measurements, is studied here. The goal of this investigation is to use Monte Carlo techniques to characterize treatment beam parameters in the presence of the detector and to compare t...

journal_title：Physics in medicine and biology

authors： Asuni G,Jensen JM,McCurdy BM

更新日期：2011-02-21 00:00:00

abstract：:This study investigated the relationship between the specific absorption rate and temperature elevation in an anatomically-based model named NORMAN for exposure to radio-frequency far fields in the ICNIRP guidelines (1998 Health Phys. 74 494-522). The finite-difference time-domain method is used for analyzing the elec...

journal_title：Physics in medicine and biology

authors： Hirata A,Asano T,Fujiwara O

更新日期：2007-08-21 00:00:00

abstract：:Lung tumors treated in breath-hold are subject to inter- and intra-breath-hold variations, which makes tumor position monitoring during each breath-hold important. A markerless technique is desirable, but limited tumor visibility on kV images makes this challenging. We evaluated if template matching  +  triangulation ...

journal_title：Physics in medicine and biology

authors： Hazelaar C,Dahele M,Mostafavi H,van der Weide L,Slotman B,Verbakel W

更新日期：2018-05-29 00:00:00

abstract：:This study evaluated the cavitation activity induced by shock wave (SW) pulses, both in vitro and in vivo, based on the area measurements of echogenic regions observed in B-mode ultrasound images. Residual cavitation bubble clouds induced by SW pulses were detected as echogenic regions in B-mode images. The temporal e...

journal_title：Physics in medicine and biology

authors： Tu J,Matula TJ,Bailey MR,Crum LA

更新日期：2007-10-07 00:00:00

abstract：:Ultrasound shock wave therapy is increasingly used for non-invasive surgery. It requires the focusing of very high pressure amplitude in precisely controlled focal spots. In transcostal therapy of the heart or the liver, the high impedance mismatch between the bones and surrounding tissues gives rise to strong aberrat...

journal_title：Physics in medicine and biology

authors： Robin J,Simon A,Arnal B,Tanter M,Pernot M

更新日期：2018-09-06 00:00:00

abstract：:This paper investigates cone-beam tomography for a wide class of x-ray source trajectories called saddles. In particular, a mathematical analysis of the number of intersections between a saddle and an arbitrary plane is given. This analysis demonstrates that axially truncated cone-beam projections acquired along a sad...

journal_title：Physics in medicine and biology

authors： Pack JD,Noo F,Kudo H

更新日期：2004-06-07 00:00:00

abstract：:Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector's intrinsic spatial resolution. To achieve images with better spatial resolution in a central reg...

journal_title：Physics in medicine and biology

authors： Li Y,Matej S,Karp JS,Metzler SD

更新日期：2015-01-21 00:00:00