Evaluation of a shock wave induced cavitation activity both in vitro and in vivo.

Abstract:

:This study evaluated the cavitation activity induced by shock wave (SW) pulses, both in vitro and in vivo, based on the area measurements of echogenic regions observed in B-mode ultrasound images. Residual cavitation bubble clouds induced by SW pulses were detected as echogenic regions in B-mode images. The temporal evolution of residual bubble clouds, generated by SWs with varying lithotripter charging voltage and pulse repetition frequency (PRF), was analyzed by measuring the time-varying behaviors of the echogenic region areas recorded in B-mode images. The results showed that (1) the area of SW-induced echogenic regions enlarged with increased SW pulse number; (2) echogenic regions in the B-mode images dissipated gradually after ceasing the SWs, which indicated the dissolution of the cavitation bubbles; and (3) larger echogenic regions were generated with higher charging voltage or PRF.

journal_name

Phys Med Biol

authors

Tu J,Matula TJ,Bailey MR,Crum LA

doi

10.1088/0031-9155/52/19/014

subject

Has Abstract

pub_date

2007-10-07 00:00:00

pages

5933-44

issue

19

eissn

0031-9155

issn

1361-6560

pii

S0031-9155(07)47913-1

journal_volume

52

pub_type

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