A modular Geant4 model of Leksell Gamma Knife Perfexion™.

abstract：:Recently, a new family of low-cost x-radiation detectors have been developed, based on semiconducting polymer diodes, which are easy to process, mechanically flexible, relatively inexpensive, and able to cover large areas. To test their potential for radiotherapy applications such as beam monitors or dosimeters, as an...

journal_title：Physics in medicine and biology

authors： Mills CA,Chan YF,Intaniwet A,Shkunov M,Nisbet A,Keddie JL,Sellin PJ

更新日期：2013-07-07 00:00:00

abstract：:An algorithm for dynamic multileaf-collimator (dMLC) tracking of a target performing a known a priori, rigid-body motion during volumetric modulated arc therapy (VMAT), has been experimentally validated and applied to investigate the potential of the Agility (Elekta AB, Stockholm, Sweden) multileaf-collimator (MLC) fo...

journal_title：Physics in medicine and biology

authors： Davies GA,Clowes P,Bedford JL,Evans PM,Webb S,Poludniowski G

更新日期：2013-07-07 00:00:00

abstract：:We experimentally investigated the SPECT recovery of I-131 activity in multiple spheres located simultaneously at different locations within a cylindrical phantom that had an elliptical cross section. The sphere volumes ranged from 209 cc down to 4.2 cc. A Prism 3000 camera and two types of parallel-hexagonal-hole col...

journal_title：Physics in medicine and biology

authors： Koral KF,Yendiki A,Dewaraja YK

更新日期：2007-02-07 00:00:00

abstract：:An open-ended coaxial probe is often used for investigating the dielectric properties of biological tissues. The present study indicates that in addition to the probe size, the penetration of the electromagnetic (EM) fields of an open-ended coaxial probe in contact with the skin is dependent on the applied frequency b...

journal_title：Physics in medicine and biology

authors： Alanen E,Lahtinen T,Nuutinen J

更新日期：1999-07-01 00:00:00

abstract：:The purpose of this study is to explain the unplanned longitudinal dose modulations that appear in helical tomotherapy (HT) dose distributions in the presence of irregular patient breathing. This explanation is developed by the use of longitudinal (1D) simulations of mock and surrogate data and tested with a fully 4D ...

journal_title：Physics in medicine and biology

authors： Kissick MW,Flynn RT,Westerly DC,Hoban PW,Mo X,Soisson ET,McCall KC,Mackie TR,Jeraj R

更新日期：2008-09-21 00:00:00

abstract：:Monolithic scintillation detectors for positron emission tomography and single-photon emission computed tomography (SPECT) imaging have many advantages over pixelated detectors. The use of monolithic crystals allows for reducing the scintillator cost per unit volume and increasing the sensitivity along with the energy...

journal_title：Physics in medicine and biology

authors： España S,Deprez K,Van Holen R,Vandenberghe S

更新日期：2013-07-21 00:00:00

abstract：:The beam quality correction factor k Q for megavoltage photon beams has been calculated for eight PTW (Freiburg, Germany) ionization chambers (Farmer chambers PTW30010, PTW30011, PTW30012, and PTW30013, Semiflex 3D chambers PTW31021, PTW31010, and PTW31013, and the PinPoint 3D chamber PTW31016). Simulations performed ...

journal_title：Physics in medicine and biology

authors： Giménez-Alventosa V,Giménez V,Ballester F,Vijande J,Andreo P

更新日期：2020-10-07 00:00:00

abstract：:In this study we investigate light penetration into skin in order to define the optimal wavelength for the treatment of port wine stains. A two-layer model (epidermis and dermis) is applied with a cylindric tube representing the ectatic blood vessel. Light propagation is calculated by the Monte Carlo method. Values fo...

journal_title：Physics in medicine and biology

authors： Kienle A,Hibst R

更新日期：1995-10-01 00:00:00

abstract：:This paper contains the recommendations of the high dose rate (HDR) brachytherapy working party of the UK Institute of Physics and Engineering in Medicine (IPEM). The recommendations consist of a Code of Practice (COP) for the UK for measuring the reference air kerma rate (RAKR) of HDR (192)Ir brachytherapy sources. I...

journal_title：Physics in medicine and biology

authors： Bidmead AM,Sander T,Locks SM,Lee CD,Aird EG,Nutbrown RF,Flynn A,IPEM Working Party.

更新日期：2010-06-07 00:00:00

abstract：:Techniques for reducing computation time in 3D photon dose calculations are addressed with specific emphasis given to the convolution/superposition approach. A single polyenergetic superposition model calculating absorbed dose per incident photon fluence (Gy cm2) was developed in terms of TERMA and a total energy depo...

journal_title：Physics in medicine and biology

authors： Aspradakis MM,Redpath AT

更新日期：1997-08-01 00:00:00

abstract：:Simultaneous near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI) were used to investigate the correlation between tumour vascular oxygenation and tissue oxygen tension dynamics in rat breast 13762NF tumours with respect to hyperoxic gas breathing. NIRS directly detected global variations in the oxyg...

journal_title：Physics in medicine and biology

authors： Xia M,Kodibagkar V,Liu H,Mason RP

更新日期：2006-01-07 00:00:00

abstract：:Clinical cerebral blood flow (CBF) maps generated through dynamic- susceptibility contrast (DSC) magnetic resonance (MR) perfusion imaging are currently cross-calibrated with PET studies. The cross-calibration is achieved by rescaling the MR CBF values so that normal white matter CBF corresponds to 22 ml/100 g/min. Ex...

journal_title：Physics in medicine and biology

authors： Chen JJ,Frayne R,Smith MR

更新日期：2005-03-21 00:00:00

abstract：:In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultr...

journal_title：Physics in medicine and biology

authors： Ma R,Zhou X,Zhang S,Yin T,Liu Z

更新日期：2016-12-21 00:00:00

abstract：:In positron emission tomography (PET), there is an increasing interest in studying not only the regional mean tracer concentration, but its variation arising from local differences in physiology, the tissue heterogeneity. However, in reconstructed images this physiological variation is shadowed by a large reconstructi...

journal_title：Physics in medicine and biology

authors： Forma J,Niemi JA,Ruotsalainen U

更新日期：2013-07-21 00:00:00

abstract：:The reference levels for testing compliance of human exposure with radio-frequency (RF) safety limits have been derived from very simplified models of the human. In order to validate these findings for anatomical models, we investigated the absorption characteristics for various anatomies ranging from 6 year old child...

journal_title：Physics in medicine and biology

authors： Kühn S,Jennings W,Christ A,Kuster N

更新日期：2009-02-21 00:00:00

abstract：:Intraoperative x-ray radiography/fluoroscopy is commonly used to assess the placement of surgical devices in the operating room (e.g. spine pedicle screws), but qualitative interpretation can fail to reliably detect suboptimal delivery and/or breach of adjacent critical structures. We present a 3D-2D image registratio...

journal_title：Physics in medicine and biology

authors： Uneri A,De Silva T,Goerres J,Jacobson MW,Ketcha MD,Reaungamornrat S,Kleinszig G,Vogt S,Khanna AJ,Osgood GM,Wolinsky JP,Siewerdsen JH

更新日期：2017-04-21 00:00:00

abstract：:At present, only a correction factor for photon transmission, k(l), is systematically applied for the entrance diaphragm of free-air chamber standards for air kerma. In the present work, the Monte Carlo code PENELOPE is used to re-evaluate k(l) for the BIPM standards and new correction factors are calculated for photo...

journal_title：Physics in medicine and biology

authors： Burns DT,Kessler C

更新日期：2009-05-07 00:00:00

abstract：:Technical advances towards high resolution PET imaging try to overcome the inherent physical limitations to spatial resolution. Positrons travel in tissue until they annihilate into the two gamma photons detected. This range is the main detector-independent contribution to PET imaging blurring. To a large extent, it c...

journal_title：Physics in medicine and biology

authors： Cal-González J,Herraiz JL,España S,Corzo PM,Vaquero JJ,Desco M,Udias JM

更新日期：2013-08-07 00:00:00

abstract：:In a recent paper (Chamberland et al 2016 Phys. Med. Biol. 61 8214) develop a new Monte Carlo code called egs_brachy for brachytherapy treatments. It is based on EGSnrc, and written in the C++ programming language. In order to benchmark the egs_brachy code, the authors use it in various test case scenarios in which co...

journal_title：Physics in medicine and biology

authors： Yegin G

更新日期：2018-02-02 00:00:00

abstract：:The presence of motion artifacts is a typical problem in thoracic imaging. However, synchronizing the respiratory cycle with computed tomography (CT) image acquisition can reduce these artifacts. We currently employ a method of in vivo respiratory-gated micro-CT imaging for small laboratory animals (mice). This proced...

journal_title：Physics in medicine and biology

authors： Walters EB,Panda K,Bankson JA,Brown E,Cody DD

更新日期：2004-09-07 00:00:00

abstract：:A leaf-setting algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimators (DMLCs). The algorithm starts with the algebraic expression for the area under the beam profile. It is shown that the coefficients in this expression can be transformed into the...

journal_title：Physics in medicine and biology

authors： Ma L,Boyer AL,Xing L,Ma CM

更新日期：1998-06-01 00:00:00

abstract：:The UMC Utrecht is constructing a 1.5 T MRI scanner integrated with a linear accelerator (Lagendijk et al 2008 Radiother. Oncol. 86 25-9). The goal of this device is to facilitate soft-tissue contrast based image-guided radiotherapy, in order to escalate the dose to the tumour while sparing surrounding normal tissues....

journal_title：Physics in medicine and biology

authors： Meijsing I,Raaymakers BW,Raaijmakers AJ,Kok JG,Hogeweg L,Liu B,Lagendijk JJ

更新日期：2009-05-21 00:00:00

abstract：:In multiple plan adaptive radiotherapy (ART) strategies of bladder cancer, a library of plans corresponding to different bladder volumes is created based on images acquired in early treatment sessions. Subsequently, the plan for the smallest PTV safely covering the bladder on cone-beam CT (CBCT) is selected as the pla...

journal_title：Physics in medicine and biology

authors： Chai X,van Herk M,Betgen A,Hulshof M,Bel A

更新日期：2012-06-21 00:00:00

abstract：:A modified sector-integration method is presented that can predict the output factors of irregular shaped electron fields even in the case of extended source to surface distance (SSD). The model takes as input measured output factors for circular inserts of various radii. These circular fields were measured at SSDs of...

journal_title：Physics in medicine and biology

authors： Choi DR,Wolters J,Mason D,Baillie A

更新日期：2000-11-01 00:00:00

abstract：:Quantitative assessment of mammographic asymmetry has been investigated for breast cancer risk prediction. A new asymmetry feature extraction method was proposed in this study to enhance the risk prediction accuracy of near-term breast cancer. Breast areas in each pair of bilateral mammographic images were divided int...

journal_title：Physics in medicine and biology

authors： Yan S,Zhang L,Song C

更新日期：2018-10-17 00:00:00

abstract：:The class of non-rigid registration methods proposed in the framework of PDE-constrained large deformation diffeomorphic metric mapping is a particularly interesting family of physically meaningful diffeomorphic registration methods. Inexact Gauss-Newton-Krylov optimization has shown an excellent numerical accuracy an...

journal_title：Physics in medicine and biology

authors： Hernandez M

更新日期：2019-01-07 00:00:00

abstract：:Dynamic PET image reconstruction is a challenging issue due to the low SNR and the large quantity of spatio-temporal data. We propose a robust state-space image reconstruction (SSIR) framework for activity reconstruction in dynamic PET. Unlike statistically-based frame-by-frame methods, tracer kinetic modeling is inco...

journal_title：Physics in medicine and biology

authors： Tong S,Alessio AM,Kinahan PE,Liu H,Shi P

更新日期：2011-04-21 00:00:00

abstract：:Three-dimensional reconstruction of cardiac vasculature from angiographic C-arm CT (rotational angiography) data is a major challenge. Motion artefacts corrupt image quality, reducing usability for diagnosis and guidance. Many state-of-the-art approaches depend on retrospective ECG-gating of projection data for image ...

journal_title：Physics in medicine and biology

authors： Schwemmer C,Rohkohl C,Lauritsch G,Müller K,Hornegger J

更新日期：2013-06-07 00:00:00

abstract：:Users of nuclear and atomic data for biomedical purposes often have difficulty in identifying the most up-to-date and appropriate sources of such data. The biomedical Subcommittee of the UK Nuclear Data Committee have prepared a list of recommended data sources available at the beginning of 1978 on radioactive decay s...

journal_title：Physics in medicine and biology

authors： Holt PD

更新日期：1979-01-01 00:00:00

abstract：:This study presents the computational dosimetry of contact currents for grounded and ungrounded human models. The uncertainty of the quasi-static (QS) approximation of the in situ electric field induced in a grounded/ungrounded human body due to the contact current is first estimated. Different scenarios of cylindrica...

journal_title：Physics in medicine and biology

authors： Chan KH,Hattori J,Laakso I,Hirata A,Taki M

更新日期：2013-08-07 00:00:00