Application of immunostaining for muscle specific actin in detection of myoepithelial cells in breast fine-needle aspirates.

Abstract:

:Myoepithelial cells play an important role in the interpretation of breast fine-needle aspiration biopsy, since these cells are believed to be a component of a benign process in breast lesions. Myoepithelial cells are usually easy to recognize, however, other cells can morphologically simulate myoepithelial cells and make the distinction difficult. To assess the feasibility of immunostaining as an adjunct to identify myoepithelial cells, we have used immunocytochemistry using monoclonal antibody against muscle specific actin (MSA) in our breast fine-needle aspirates. Herein, we report our experience in immunocytochemical detection of myoepithelial cells using labeled Streptavidin Biotin Detection System on destained Papanicolaou stained smears and cell block preparations obtained from breast aspirates.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Masood S,Lu L,Assaf-Munasifi M,McCaulley K

doi

10.1002/dc.2840130115

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

71-4

issue

1

eissn

8755-1039

issn

1097-0339

journal_volume

13

pub_type

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