Intraductal carcinoma in a male breast: diagnosis by nipple discharge cytology.


:We describe a case of intraductal carcinoma (comedo type) in a 50-yr-old male. The patient had presented with a bloody nipple discharge, which had shown malignant cells on cytologic examination. In current clinical practice, the use of nipple discharge cytology as a screening and diagnostic tool for breast carcinoma is largely supplemental; however, this case illustrates the occasional utility of nipple discharge cytology in the diagnosis of early breast carcinoma.


Diagn Cytopathol


Diagnostic cytopathology


Hirschman SA,Hoda SA,May M,Cody HS 3rd




Has Abstract


1995-06-01 00:00:00












  • Granulocyte colony-stimulating factor-producing small-cell carcinoma of the uterine cervix: report of a case.

    abstract::A case of granulocyte colony-stimulating factor (G-CSF)-producing small-cell carcinoma of the uterine cervix is described. In a 70-yr-old woman, clusters of small cells with hyperchromatic nuclei at a high nuclear/cytoplasmic ratio were detected cytologically in the cervix. These clusters were diagnosed as a small-cel...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Watanabe A,Wachi T,Omi H,Nishii H,Ochiai K,Tanaka T,Endo Y

    更新日期:2000-10-01 00:00:00

  • Follicular lesions of the thyroid: a retrospective study of 1,348 fine needle aspiration biopsies.

    abstract::Fine needle aspiration (FNA) has proven to be an effective tool in management of patients with thyroid nodules. However, the diagnosis of follicular patterned lesions can be challenging. The surgical and cytopathology computer database at a large referral medical center was searched for cases that had both cytologic a...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Wu S,DeMay RM,Papas P,Yan B,Reeves W

    更新日期:2012-05-01 00:00:00

  • Functional parathyroid carcinoma. Cytology, histology, and ultrastructure of a case.

    abstract::A case of a functional parathyroid carcinoma that recurred 1 year after being resected is presented. The clinical and laboratory data and the histologic structure are presented with confirmatory electron microscopy. The preoperative aspiration biopsy showed findings suggestive of parathyroid carcinoma although simulta...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: de la Garza S,Flores de la Garza E,Hernández Batres F

    更新日期:1985-07-01 00:00:00

  • Are adjunctive markers useful in routine cervical cancer screening? Application of p16(INK4a) and HPV-PCR on ThinPrep samples with histological follow-up.

    abstract::The objectives of the study were to evaluate 1) the diagnostic sensitivity and specificity of p16(INK4a) as a marker for high-grade cervical lesions, 2) the results of a real-time polymerase chain reaction detecting high-risk human papillomavirus, and 3) the interobserver variability of the p16(INK4a) interpretation.A...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Schledermann D,Andersen BT,Bisgaard K,Dohse M,Ejersbo D,Hoelund B,Horal P,Lindh M,Ryd W

    更新日期:2008-07-01 00:00:00

  • Fine-needle aspiration biopsy findings in marginal zone B cell lymphoma.

    abstract::Marginal zone B cell lymphomas (MZBCLs) represent a category of non-Hodgkin's lymphoma which may arise in a wide variety of extranodal organs where they are termed low grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT). MZBCLs may involve primarily lymph nodes and or spleen where they are designated mo...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Matsushima AY,Hamele-Bena D,Osborne BM

    更新日期:1999-04-01 00:00:00

  • Serous fluid cytology as a means of detecting hemophagocytosis in Epstein-Barr virus-induced autoimmune hemolytic anemia.

    abstract::The case of a 22-yr-old male who after a brief febrile episode developed autoimmune hemolytic anemia and right pulmonary infiltrate with pleural effusion is presented. Cytologic examination of the pleural fluid revealed lymphocytosis and hemophagocytosis, primarily of red blood cells (RBCs) by mature histiocytes. Ther...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Zaharopoulos P

    更新日期:2001-10-01 00:00:00

  • Solitary pleural amyloid nodules occurring as coin lesions diagnosed by fine-needle aspiration biopsy.

    abstract::Solitary pleural amyloid nodule is rare and radiologically can mimic neoplastic lesions. This report describes two cases of this entity diagnosed by fine-needle aspiration biopsy in patients without systemic amyloid deposits. The histologic, ultrastructural, and cytologic features are described. ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Kaw YT,Esparza AR

    更新日期:1991-01-01 00:00:00

  • Localization of p53 and proliferating cell nuclear antigen in fine-needle aspirates of benign and primary malignant tumors of the human breast: an immunocytochemical study using supersensitive monoclonal antibodies and the biotin-streptavidin-amplified me

    abstract::p53 and proliferating cell nuclear antigen (PCNA) status was determined in fine-needle aspirates (FNAs) and methacarn-fixed paraffin-embedded tissue sections of six fibroadenomas and 50 primary breast carcinomas using supersensitive monoclonal antibodies and the biotin-streptavidin-amplified method. Nuclear accumulati...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Alexiev BA

    更新日期:1996-11-01 00:00:00

  • Koilocytosis: correlations with high-risk HPV and its comparison on tissue sections and cytology, urothelial carcinoma.

    abstract::The aim of this study were (1) To correlate koilocytosis with high risk HPV(HrHPV) DNA in urinary bladder carcinoma and (2) To compare detection of koilocytosis on tissue sections and urine cytology. Biopsy and cytologic specimens from 33 patients of urinary bladder carcinoma were analyzed. HPV DNA was detected by PCR...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Aggarwal S,Arora VK,Gupta S,Singh N,Bhatia A

    更新日期:2009-03-01 00:00:00

  • Fine-needle aspiration cytology with histological correlation of chordoma metastatic to the lung: a diagnostic dilemma.

    abstract::Chordoma is an uncommon tumor initially believed to be benign due to the rarity of its metastasis. Cytological, morphological, and immunohistochemical features of chordoma, relating to its origin from notochordal remnants, allows for its accurate diagnosis. A 75-year-old man with a known history of tuberculosis (TB) p...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Kanthan R,Senger JL

    更新日期:2011-12-01 00:00:00

  • Pregnancy-associated anaplastic large-cell lymphoma of the breast: a rare mimic of ductal carcinoma.

    abstract::Anaplastic large-cell lymphoma (ALCL) is a rare T-cell lymphoma typically seen in children and young adults. It has been described in numerous sites; however, the breast is one of the least common locations. We herein report a case of ALCL arising in the breast of a 36-yr-old pregnant woman. To our knowledge this is t...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Iyengar P,Reid-Nicholson M,Moreira AL

    更新日期:2006-04-01 00:00:00

  • Fascin stain as a potential marker of invasiveness in carcinomas of the urinary bladder: a retrospective study with biopsy and cytology correlation.

    abstract::The evaluation of invasion in urothelial carcinomas of the urinary bladder cannot be determined on cytology and can be particularly challenging in biopsy cases with limited sampling. Recent studies of bladder resection specimens suggest that fascin overexpression may be a marker of aggressive urothelial carcinomas and...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: McKnight R,Cohen C,Siddiqui MT

    更新日期:2011-09-01 00:00:00

  • Two AgNOR counts in fine-needle aspirates of lymphoproliferative disorders compared with acridine orange flow cytometry.

    abstract::Studies have shown that argyrophilic nucleolar organizer region-associated proteins (AgNORs) may correlate with DNA ploidy and/or proliferative activity in neoplastic and non-neoplastic conditions. However, studies have estimated only the mean AgNOR counts. Here we used two AgNOR counts, one of which may correlate wit...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Mourad WA,Katz RL,Sembera D,Atkinson EN,el-Naggar AK

    更新日期:1992-01-01 00:00:00

  • Aluminum silicate-containing psammoma bodies in a cervicovaginal smear (Pap): cytological, ultrastructural, and radiographic microprobe studies.

    abstract::Psammoma body is a rare finding in a cervicovaginal smear and can be associated with either benign or malignant diseases. Here we report a case to illustrate the association of psammoma bodies with benign granulomatous reactions to a foreign material (aluminum silicate). ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Li S,Boudousquie AC,Baloch ZW,Minda JM,Gupta PK

    更新日期:1999-08-01 00:00:00

  • Lymphoid cell aggregates: a useful clue in the fine-needle aspiration diagnosis of follicular lymphomas.

    abstract::Among the various types of lymphoma, follicular lymphoma (FL) is known to have significant limitations in cytologic diagnosis by the fine-needle aspiration (FNA) method. The diagnostic accuracy (DA) for non-Hodgkin's lymphoma (NHL) by FNA was evaluated by review of 82 cases of histologically proved NHL after prior FNA...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Suh YK,Shabaik A,Meurer WT,Shin SS

    更新日期:1997-12-01 00:00:00

  • Adamantinoma-like Ewing Sarcoma of the thyroid gland: Cytomorphologic, phenotypic and molecular features.

    abstract::Adamantinoma-like Ewing Sarcoma (ALES) is a rare subtype of Ewing sarcoma family of tumors (EFTs) which are defined by their EWSR1 gene rearrangements. We present a case of a 15-year old female with a swelling in her anterior neck of 4 months duration which had recently begun to rapidly grow in size. Fine needle aspir...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Chikeka I,Sung S,Tiscornia-Wasserman P,Cimic A

    更新日期:2020-05-30 00:00:00

  • Detection of tumor cells of serous tubal intraepithelial carcinoma (STIC) in cervical smears and rapid development of the ovarian involvement: A case report.

    abstract::Serous tubal intraepithelial carcinoma (STIC) has attracted attention as a precursor lesion of high-grade serous carcinoma (HGSC) of the ovary. We report the rare case of a woman in whom adenocarcinoma cells were detected in cervical smears and demonstrated to be derived from STIC in the fimbria. The patient was a 48-...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Shintaku M,Taniguchi H,Yamamoto Y,Kono F,Sumitomo M

    更新日期:2018-11-01 00:00:00

  • Polymicrobial lung infection in postrenal transplant recipient diagnosed by fine-needle aspiration cytology.

    abstract::Tuberculous and fungal infections are among the non-neoplastic lesions of the lung, in which fine-needle aspiration cytology (FNAC) has proven to be a useful technique in both immunocompromised and immunocompetent patients. The presence of polymicrobial infection in a renal transplant recipient is documented in the li...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Duggal R,Rajwanshi A,Gupta N,Lal A,Singhal M

    更新日期:2010-04-01 00:00:00

  • Diagnostic value of fine-needle aspiration in supraclavicular lymphadenopathy: a study of 106 patients and review of literature.

    abstract::The simplicity and safety of the fine-needle aspiration (FNA) make it a useful procedure for the initial evaluation of supraclavicular lymphadenopathy. We analyzed data (106 patients) in combination with the data of three recently published studies (total 301 patients) to make the observations more meaningful. The use...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审


    authors: Nasuti JF,Mehrotra R,Gupta PK

    更新日期:2001-12-01 00:00:00

  • Scrape cytology of pemphigus vulgaris of the nipple, a mimicker of Paget's disease.

    abstract::A case of histologically and immunocytochemically confirmed pemphigus vulgaris of the nipple examined by scrape cytology is reported. The scrape cytology showed isolated and somewhat loosely clustered cells with basophilic cytoplasm and vesicular hyperchromatic nuclei dysplaying prominent nucleoli, suggesting Paget's ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Kobayashi TK,Ueda M,Nishino T,Kibe S,Higashida T,Watanabe S

    更新日期:1997-02-01 00:00:00

  • Ultrasound-guided fine-needle aspiration biopsy remains a valid approach in the evaluation of nonpalpable breast lesions.

    abstract::The use of ultrasound-guided fine-needle aspiration (FNA) biopsy for nonpalpable breast lesions varies considerably. This retrospective study stresses the role of breast FNA in evaluating sonographically suspicious nonpalpable breast masses using a probabilistic reporting system. One hundred and eight consecutive ultr...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Liao J,Davey DD,Warren G,Davis J,Moore AR,Samayoa LM

    更新日期:2004-05-01 00:00:00

  • Cytomorphologic features of metastatic urothelial carcinoma in serous effusions.

    abstract::Metastatic urothelial carcinoma (UC) to serous effusion (SE) is extremely rare and its cytomorphological features have only been described in case reports. In this study, we searched the pathology database at University of Michigan for SEs due to metastatic UC in the last 20 years. A total of 25 cases from 20 patients...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Huang CC,Attele A,Michael CW

    更新日期:2013-07-01 00:00:00

  • A comparative needle study: EUS-FNA procedures using the HD ProCore(™) and EchoTip(®) 22-gauge needle types.

    abstract::The specific needle sizes/types used in performing endoscopic ultrasound-guided fine needle aspirations (EUS-FNA) vary. The HD ProCore(™) is a 22-gauge beveled needle allowing for core biopsy along with aspiration material. In this study we compare this needle with a standard 22-gauge needle. Between April 1, 2011 and...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Witt BL,Adler DG,Hilden K,Layfield LJ

    更新日期:2013-12-01 00:00:00

  • Nonsebaceous lymphadenoma of the parotid gland: cytopathologic findings and differential diagnosis.

    abstract::Lymphadenomas (sebaceous and nonsebaceous types) of the salivary glands are extremely uncommon benign neoplasms. There are rare published reports of cytopathologic characteristics of "nonsebaceous lymphadenomas" of the parotid gland. We report herein, the case of an 80-year-old female who was evaluated at The Johns Ho...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Castelino-Prabhu S,Li QK,Ali SZ

    更新日期:2010-02-01 00:00:00

  • Cytologic characteristics of clear-cell sarcoma of the kidney (CCSK) in fine-needle aspiration biopsy (FNAB): a report of 4 cases.

    abstract::The cytologic findings observed in fine-needle aspiration biopsy (FNAB) of four cases of clear-cell sarcoma of the kidney (CCSK) are reported. Smears contained a monomorphic population of cells exhibiting non-descriptive cytoplasm and almost nude round to oval nuclei with smooth contour, evenly dispersed fine chromati...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Drut R,Pomar M

    更新日期:1991-01-01 00:00:00

  • Radiation-induced changes in the breast: a potential diagnostic pitfall on fine-needle aspiration.

    abstract::The authors report a case of fine-needle aspiration (FNA) of a breast mass in a 36-year-old woman with previous history of lumpectomy and therapeutic radiation for breast carcinoma. The changes seen were interpreted as recurrent carcinoma, while subsequent biopsy showed only radiation changes. Radiation-induced change...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Dornfeld JM,Thompson SK,Shurbaji MS

    更新日期:1992-01-01 00:00:00

  • Diagnostic accuracy of fine-needle aspiration cytology of palpable breast masses: an SROC curve with fixed and random effects linear meta-regression models.

    abstract::We used various meta-analytic methods to compare 25 studies describing fine-needle aspiration (FNA) cytologic analyses performed from 1984 to 2007 on palpable breast masses. We found that in the 25 studies examined, the sensitivity ranged from 78% to 100%, the specificity ranged from 76% to 100%, and the diagnostic od...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,meta分析


    authors: Akçil M,Karaağaoğlu E,Demirhan B

    更新日期:2008-05-01 00:00:00

  • Adenoviral cytopathic changes in pleural fluid: A unique cytological presentation mimicking malignancy.

    abstract::Adenoviruses are emerging as important viral pathogens in immunocompromised patients due to immunodeficiency diseases and recently hematopoietic stem cell and solid organ transplant recipients, impacting morbidity and even mortality. Immunocompromised children are prone to respiratory infection, due to alterations in ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Harbhajanka A,Michael CW

    更新日期:2020-11-16 00:00:00

  • A case of endocervical minimal deviation adenocarcinoma with varicolored cytopathologic features on Pap smear.

    abstract::We report a case of minimal deviation adenocarcinoma (MDA) of the uterine cervix showing varicolored cytopathologic features on Papanicolaou (Pap) smear, which may indicate features suggestive of lobular endocervical glandular hyperplasia (LEGH)-adenocarcinoma sequence. A 57-year-old woman presented with a profuse amo...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Omori M,Kondo T,Nakazawa K,Shinohara S,Watanabe Y,Fukasawa H,Nakazawa T,Hashi A,Hirata S

    更新日期:2018-08-01 00:00:00

  • Metastatic, sarcomatoid, and PSA- and PAP-negative prostatic carcinoma: diagnosis by fine-needle aspiration.

    abstract::Fine-needle aspiration of prostatic carcinoma usually yields an acinar carcinoma that is immunoreactive for prostatic-specific antigen (PSA) and prostatic acid phosphatase (PAP). We report on two FNAs of metastatic sarcomatoid prostatic carcinoma that were PSA- and PAP-negative. Our methods included a review of the me...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Renshaw AA,Granter SR

    更新日期:2000-09-01 00:00:00