Oral pemphigus vulgaris: Liquid-based cytological findings and pitfalls.

Abstract:

:Pemphigus vulgaris (PV) is a chronic autoimmune bullous disease characterized by the formation of suprabasal cleavage and acantholysis. As this disease almost always affects the oral mucosa, conventional cytological smears of oral lesions can be used for the initial diagnosis of PV. We report two cases of PV that were initially diagnosed based on cytological smears of an oral sample. As atypical squamous cells were present even in the liquid-based cytological (LBC) smears of the oral lesion in these two cases, this ultimately led to the misinterpretation of squamous cell carcinoma. These findings demonstrate that cytological mimicry of oral PV can occur in malignant cases when there is an absence of appropriate clinical information.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Kondo S,Kawashima J,Kobata K,Ohgawara T,Tanaka S,Nabeshima K,Kikuta T

doi

10.1002/dc.23792

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

63-66

issue

1

eissn

8755-1039

issn

1097-0339

journal_volume

46

pub_type

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