Cytologic distinction between bronchioalveolar carcinoma and reactive/reparative respiratory epithelium: a cytomorphometric analysis.

Abstract:

:Cytologically, the distinction between bronchioalveolar carcinoma and reactive/reparative processes of respiratory epithelium can be difficult. Retrospectively, we have identified 11 consecutive cases of bronchioalveolar carcinoma from the cytology files of University Missouri-Kansas City/Truman Medical Center. On average, a combined 5.71 cytologic/histologic procedures were performed before reaching a definitive diagnosis for this group. An additional seven random cases of reactive/reparative respiratory cases of adult respiratory distress syndrome patients were used as a control. Cytomorphometric analysis was performed. The mean average nuclear diameter for the carcinoma group was 13.76 microns and for the reactive/reparative group was 13.29 microns. There was no statistical difference between the two groups (paired student t test, P > .05). It appears from our data that mean nuclear diameter is not a discriminator for the cytologic distinction between bronchioalveolar carcinoma and reactive/reparative respiratory epithelium and that the accepted cytologic parameters of for bronchioalveolar carcinoma are more valid.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Fiorella RM,Gurley SD,Dubey S

doi

10.1002/(sici)1097-0339(199810)19:4<270::aid-dc8>3

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

270-3

issue

4

eissn

8755-1039

issn

1097-0339

pii

10.1002/(SICI)1097-0339(199810)19:4<270::AID-DC8>3

journal_volume

19

pub_type

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