Serosal balls detected immunocytochemically in peritoneal lavage obtained during surgery.

Abstract:

:Using the immunoperoxidase technique, we studied "serosal balls," which have features resembling those of cells from primary and metastatic tumors, and may thus complicate cytodiagnosis. Serosal balls were detected in 32 (18%) of 174 peritoneal washings. The balls consisted of oval clusters of cells in solid masses surrounded by flattened cells. The interior of the serosal balls was stained green with Papanicolaou method, showing the presence of homogeneous amorphous material, sometimes stained in a filamentous pattern. Almost all serosal balls were stained immunocytochemically for both keratin and vimentin. The interior was stained with antibodies against collagen types I and III. Therefore, these balls were fragments of serous membrane, and contained fibrous tissue and mesothelial cells.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Sasaki M,Wakasa K,Sakurai M,Iwa N

doi

10.1002/dc.2840130208

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

124-7

issue

2

eissn

8755-1039

issn

1097-0339

journal_volume

13

pub_type

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