Abstract:
:Adenoviruses are emerging as important viral pathogens in immunocompromised patients due to immunodeficiency diseases and recently hematopoietic stem cell and solid organ transplant recipients, impacting morbidity and even mortality. Immunocompromised children are prone to respiratory infection, due to alterations in their immune system. When confronted with diseases involving the pleural effusions, such as viral infections, the diagnostic problem becomes more complex and special effort is needed to recognize and characterize them accurately and to differentiate them from other pathologies such as malignancies. However, cytology of adenoviral infection in pleural effusions has not been reported before. We report a case of an adenovirus infection of the pleural effusion which included lymphocytosis associated with background atypical cells showing a cytopathic effect (cytoplasmic viral particles). The differential diagnosis included lymphoma and infections. Immunohistochemical stain for adenovirus was positive and confirmed by molecular studies. Usually in viral infections there are cytopathic changes due to viral particles affecting epithelial cells but this case is unique as the viral particles were identified in macrophages. We discuss the significance of such infection in comparison with other viral changes indigenous to the pleural effusions, which could also occur in such specimens.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Harbhajanka A,Michael CWdoi
10.1002/dc.24662subject
Has Abstractpub_date
2020-11-16 00:00:00eissn
8755-1039issn
1097-0339pub_type
杂志文章abstract::Fine-needle aspiration cytology (FNAC) is an acknowledged method for diagnosing prostate cancer. False-positive results are uncommon, but concerns have been raised that prostatic intraepithelial neoplasia (PIN) could be misinterpreted as carcinoma. Therefore, we attempted to describe cytological features of PIN. Cells...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20417
更新日期:2006-05-01 00:00:00
abstract::In this report, the authors examined the characteristic features of morphology and molecular biology of Ki-67, p53, Bcl-2, and cyclooxygenase-2 (Cox-2) immunocytochemistry in low-grade endometrioid endometrial carcinoma (LG-ENEC) and disordered proliferative (DP)/benign hyperplastic (BH) endometrium. We carried out a ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23010
更新日期:2014-02-01 00:00:00
abstract::Lobular carcinoma in situ (LCIS) of the breast is a recognized marker for increased risk of invasive carcinoma and has well-established histologic criteria. However, its detection and diagnosis on FNA of breast has not been well defined. Cytology slides (all ThinPrep) of 11 cases with biopsy-proven LCIS at Beth Israel...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20247
更新日期:2005-05-01 00:00:00
abstract::Metastatic carcinoma to the pancreas is uncommon and head and neck squamous carcinoma metastatic to the pancreas is extremely rare. Metastatic squamous cell carcinoma to the pancreas presents a unique diagnostic challenge: in addition to mimicking the rare primary squamous cell carcinoma of the pancreas based on cytol...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23769
更新日期:2017-11-01 00:00:00
abstract::Four cases of renal angiomyolipoma (AML) diagnosed by fine-needle aspiration biopsy (FNAB) are reported. One case was associated with the clinical complex of tuberous sclerosis. The tumors were solitary in two cases and multiple and bilateral in the fourth. The cytologic features of the four cases were similar to thos...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840100110
更新日期:1994-01-01 00:00:00
abstract::The Papanicolaou Society of Cytopathology has developed a set of guidelines for pancreaticobiliary cytology including indications for endoscopic ultrasound (EUS) and fine-needle aspiration (FNA) biopsy, techniques for EUS-FNA, terminology and nomenclature to be used for pancreaticobiliary disease, ancillary testing, a...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,实务指引
doi:10.1002/dc.23095
更新日期:2014-04-01 00:00:00
abstract::A case of histologically and immunocytochemically confirmed pemphigus vulgaris of the nipple examined by scrape cytology is reported. The scrape cytology showed isolated and somewhat loosely clustered cells with basophilic cytoplasm and vesicular hyperchromatic nuclei dysplaying prominent nucleoli, suggesting Paget's ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199702)16:2<156::aid-dc13>
更新日期:1997-02-01 00:00:00
abstract:INTRODUCTION:The incidence of thyroid cancer is increasing which can be attributed in part to improved ultrasonography (US) methods and increased detection of incidental thyroid carcinomas (ITC). We aimed to compare ITC with nonincidental thyroid carcinomas (NITC) in this study. METHODS:Retrospective analyses of 906 i...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24117
更新日期:2019-05-01 00:00:00
abstract::Clear cell hepatocellular carcinoma (CCHCC) is an uncommon morphologic variant of HCC and rarely invades into the main bile ducts. Here we describe a case of CCHCC that was diagnosed by bile duct brushing cytology. Liquid-based preparation of brushing specimen showed clusters of atypical epithelial cells with abundant...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23397
更新日期:2016-02-01 00:00:00
abstract::Synovial sarcoma (SS) is one of the most common soft tissue tumors that typically presents in the extremities of young adults, but may occur at any site and affect children during the first decade. Herein we discuss a 12-yr-old male who complained of left foot pain and plantar mass. A fine-needle aspiration biopsy of ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20566
更新日期:2006-11-01 00:00:00
abstract::Preoperative chemotherapy for locally advanced breast carcinoma (stage IIIA,B) is increasingly utilized demonstrating a 70 to 95% objective response and 15 to 35% complete response. A 70-yr-old woman presented with a 9 cm left upper outer quadrant breast mass associated with overlying skin redness and a 2.5 cm left ax...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840100413
更新日期:1994-01-01 00:00:00
abstract::We present a case in which a primary diagnosis of gout was made by fine-needle aspiration. The patient had a right distal ulnar mass, and the initial clinical and radiological diagnoses were that of giant cell tumor of tendon sheath. While tophi are the hallmark of gout, they rarely undergo aspiration because of the k...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0339(199609)15:3<246::AID-DC14>
更新日期:1996-09-01 00:00:00
abstract::Pancreatic pheochromocytomas are rare and typically diagnosed by local resection. We present the first reported case of metastatic pheochromocytoma to the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and cytology. A 67-year-old female presented with 2 to 3 months of abdominal pai...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.24326
更新日期:2020-03-01 00:00:00
abstract::Corpora amylacea are predominantly found in the brain, prostate, and lung. Recent characterizations of their components suggest an important role in protection and clearing. We report the presence of corpora amylacea in pleural effusion in a patient with lupus. The differential diagnoses and potential significance are...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24684
更新日期:2020-12-21 00:00:00
abstract:BACKGROUND:The International Academy of Cytology (IAC) Yokohama system is a recently proposed system for reporting breast cytology by fine needle aspiration biopsies (FNAB). Multiple studies are needed to confirm the risk of malignancy (ROM) of the various reporting categories of this system. The present article studie...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24632
更新日期:2021-02-01 00:00:00
abstract::A variety of inflammatory and neoplastic scalp lesions are encountered in surgical pathology. However, the literature on fine-needle aspirations (FNAs) of the scalp is exceedingly rare. We report on a series of 70 FNAs involving cutaneous and subcutaneous lesions on the scalp. A total of 70 fine-needle aspirations of ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/1097-0339(200007)23:1<35::aid-dc8>3.0.co;2
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The incidence of anal carcinoma has risen in recent decades. Exfoliative cytology screening of selected high risk patients is performed in many centers. Unsatisfactory cytology results are frustrating to patients, clinicians, and laboratorians. The aim of this study is to ascertain outcomes of patients with ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23858
更新日期:2018-02-01 00:00:00
abstract::Fine-needle aspiration (FNA) of the thyroid for papillary carcinomas is highly sensitive. We sought to determine if the sensitivity of FNA for papillary carcinoma is correlated with the size of the tumor. We reviewed the results of thyroid resections for the last 12 years and correlated the findings with clinical and ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21411
更新日期:2011-07-01 00:00:00
abstract::Fine-needle aspiration (FNA) is a valuable technique to use in the evaluation of breast lesions; however, inadequate and discrepant diagnoses do occur. To identify the source and nature of inaccuracies related to the method we studied 39 cases in which FNA posed diagnostic problems. These problems could be attributed ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840070523
更新日期:1991-01-01 00:00:00
abstract::Peculiar ring-like structures identified as Liesegang rings (LRs) were found in renal cyst fluid from three patients with benign renal cysts. They ranged in size from 5 to 820 mu. Most had a double-layer outer wall with equally spaced radial cross-striations and an amorphous central nidus. Special stains were performe...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840060310
更新日期:1990-01-01 00:00:00
abstract::While metastatic tumors to bone or lymph nodes from previously known primaries are often successfully diagnosed via fine-needle aspiration (FNA), a metastatic deposit in a patient with no previously known cancer may pose a diagnostic dilemma. Here, we present a case of metastatic papillary thyroid carcinoma that prese...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23031
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Swellings in the hand and wrist are frequently encountered in clinical practice and fine needle aspiration cytology (FNAC) is used as a primary diagnostic modality in most of them. A wide spectrum of lesions can be encountered at these sites. The aim of this study was to report the prevalence and spectrum of...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24050
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The triple test, i.e., cytology combined with clinical and radiological findings, is the goal for accurate assessment of palpable breast lesions. Because of the limitations of fine-needle aspiration cytology (FNAC), its utility has somewhat decreased nationwide. We have been using a combination of physical e...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23380
更新日期:2015-12-01 00:00:00
abstract::Tenosynovial giant cell tumor (TSGCT) is a highly recurrent benign tumor of the extremities. Wide local excision is usually sufficient to achieve its recurrence-free outcome. However, that needs a confident pre-operative cytological diagnosis as TSGCT. Aspirates from this tumor express the characteristic polymorphic c...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23825
更新日期:2018-03-01 00:00:00
abstract::We report the fine-needle aspiration cytology of a case of metastatic small cell osteosarcoma to the liver with rosette formation, originating from distal femur, in a 36-year-old female. The aspirate of the liver metastases revealed a relatively monomorphic population of mitotically active small blue round cells arran...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.22894
更新日期:2014-02-01 00:00:00
abstract::Alveolar soft part sarcoma (ASPS) is a rare, high-grade, epithelial-like sarcoma that shows characteristic histopathologic findings. Although a chromosomal anomaly that seems specific has been recently described, its diagnosis is based on histologic and ultrastructural features. The tumor shows no specific immunohisto...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10139
更新日期:2002-08-01 00:00:00
abstract::Metaplastic breast carcinomas (MBCs) are not only uncommon neoplasms but also show a myriad of cytomorphologic patterns in aspiration samples. These tumors comprise less than 5% of breast malignancies and have an uncertain prognosis. In this study, the fine-needle aspiration cytologic features of 14 MBCs with the iden...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199901)20:1<10::aid-dc3>3.
更新日期:1999-01-01 00:00:00
abstract::Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) has become a widely used method of pre-operatively evaluating pancreatic masses. This technique introduces gastrointestinal contamination into the specimen, which poses a diagnostic pitfall. The cytomorphologic features of these contaminants have no...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20343
更新日期:2005-12-01 00:00:00
abstract::Sclerosing polycystic adenosis (SPA) is a recently described, rare lesion of the salivary gland analogous to fibrocystic disease of the breast. Recognition of this benign entity is important since the differential diagnosis includes other more common benign and malignant salivary gland neoplasms, particularly mucoepid...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20671
更新日期:2007-07-01 00:00:00
abstract::Fine-needle aspiration cytology (FNAC) is a technique that can overcome tissue-sampling disaggregation problems related to DNA flow cytometry analysis. The aim of this study, with long-term follow-up (median, 72 mo), was to investigate the prognostic value of DNA ploidy and S-phase fraction (SPF) in patients with non-...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10298
更新日期:2003-10-01 00:00:00