Abstract:
:Location-guided screening is a feature of the AutoPap primary screening software. Areas of the smear most likely to contain an abnormality are identified for prompt review by the cytotechnologist, thereby facilitating diagnostic accuracy and reducing laboratory workload. A two-armed retrospective study comprising 6,000 conventional smears was undertaken to compare this approach with the current practice of full manual screening of conventional smears. Discrepant diagnoses between the two study arms were subject to an internal discrepancy review process to determine the final truth diagnosis. Analysis of the results show that AutoPap location-guided screening is at least equivalent to current practice when detecting high-grade or suspected high-grade smears. However, the device does not detect low-grade abnormalities, unsatisfactory smears, an endocervical component or organisms, as well as standard screening. The device also assigns a numerical score to each slide, with abnormal smears allocated a higher rank. Slide ranking was found to be of value in triaging abnormal smears for prompt screening and reporting. The performance of the primary screening software was found to be comparable to previous studies, with the majority of abnormal smears being selected by the instrument for manual review.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Stevens MW,Milne AJ,Parkinson IH,Nespolon WW,Fazzalari NL,Arora N,Dodd TJdoi
10.1002/dc.20081subject
Has Abstractpub_date
2004-08-01 00:00:00pages
94-9issue
2eissn
8755-1039issn
1097-0339journal_volume
31pub_type
杂志文章abstract::Adenomyoepithelioma is an uncommon tumor of the breast which clinically presents as a discrete nodule and histologically is composed of lumenal spaces lined by a mixture of epithelial and myoepithelial cells. It has a spectrum of histologic appearances which are gradually gaining wider recognition. There are, however,...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840120311
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Sebaceous lymphadenomas and sebaceous lymphadenocarcinomas are uncommon neoplasms occurring predominately within the parotid gland. Cytomorphology of these neoplasms is rarely reported. Occasional reports have discussed the cytomorphological features of these neoplasms but criteria distinguishing sebaceous l...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24357
更新日期:2020-05-01 00:00:00
abstract::Our objectives were to study the types and incidence of thyroid follicular lesions coexisting with Hashimoto's thyroiditis (HT), the pitfalls in their cytodiagnosis, and the effect on management. All cases of HT diagnosed by fine-needle aspiration (FNA) and/or histology over a 7-yr period were retrospectively studied....
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10206
更新日期:2003-01-01 00:00:00
abstract::Epithelioid angiosarcomas are extremely rare tumors associated with poor prognosis and early metastases. Its epithelioid cytomorphology and limited vasoformation make it difficult to distinguish from more common malignancies, such as, carcinoma. This can be a potential diagnostic pitfall for the cytopathologist. In th...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21187
更新日期:2010-02-01 00:00:00
abstract::Anaplastic large cell lymphoma (ALCL), according to the new WHO classification, is a diagnosis limited to T/NK cell lymphomas. We present a case that demonstrates a new morphologic variant of ALCL with significant possible pitfalls for the cytopathologist. A fine-needle aspiration biopsy of a cervical lymph node showe...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10056
更新日期:2002-02-01 00:00:00
abstract::Ultrasound examination (US) is an essential tool in the evaluation of thyroid nodules. The size determined by US is used to distinguish between clinical vs. nonclinical thyroid nodules i.e. greater than or equal to or less than 1 cm. In this study, we evaluated the concordance between the sizes of thyroid nodules meas...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20714
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:GATA-3 is a transcription factor involved in human tissue growth and differentiation. It is a potential marker for breast carcinoma origin in metastasis and predictive of good prognosis. We aim to evaluate the role of GATA3 in determining the breast origin of metastatic adenocarcinoma in malignant effusions ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23521
更新日期:2016-09-01 00:00:00
abstract::Disseminated histoplasmosis (DH) is a systemic granulomatous disease caused by the fungus Histoplasma capsulatum. This disease occurs mainly in immunocompromised individuals with CD 4 counts less than 200 cell/µL and is rarely noted in immunocompetent person. In India, this disease has been reported from several parts...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23742
更新日期:2017-09-01 00:00:00
abstract::Fine-needle aspirates of three thyroid nodules displayed hypercellularity and papillary tissue fragments that suggested neoplasms. Neither microfollicles (either empty or with inspissated colloid) nor the characteristic nuclei of papillary carcinoma were evident. Surgical specimens contained adenomatoid nodules with f...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199705)16:5<454::aid-dc14>
更新日期:1997-05-01 00:00:00
abstract::Two cases of small-cell carcinoma of the ovary in the ascitic fluid and peritoneal/pelvic washings of a 30- and 28-yr-old woman, respectively, are presented and discussed. Smear preparations from the ascitic fluid showed loose clusters and single malignant cells with scant cytoplasm and nuclei with smooth to irregular...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840110314
更新日期:1994-01-01 00:00:00
abstract::Cytological evaluation of cervical smears has been carried out in 4,338 women attending the Gynecology and Obstetrics Department and Family Planning Clinic of Queen Mary's Hospital, Lucknow, India, since April 1971. The incidence of cervical dysplasia was found to be 4.6% (205 out of 4,338) in the series, while malign...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840030107
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:The incidence of anal carcinoma has risen in recent decades. Exfoliative cytology screening of selected high risk patients is performed in many centers. Unsatisfactory cytology results are frustrating to patients, clinicians, and laboratorians. The aim of this study is to ascertain outcomes of patients with ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23858
更新日期:2018-02-01 00:00:00
abstract::Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal tumors with immunohistochemical co-expression of melanocytic and myoid markers. Vaginal PEComas have been described in only nine cases so far. We describe the case of a 65-year-old female with a large growth in the left lateral vaginal wall. Biopsy im...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.24402
更新日期:2020-05-01 00:00:00
abstract::Fine-needle aspiration cytology, immunocytochemistry, and electron microscopic findings are described in a case of glycogen-rich clear cell carcinoma of the breast. The aspirate contained many small and large papillary cell groups and numerous single tall columnar cells with apical cytoplasmic projections and mild to ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840120115
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Swellings in the hand and wrist are frequently encountered in clinical practice and fine needle aspiration cytology (FNAC) is used as a primary diagnostic modality in most of them. A wide spectrum of lesions can be encountered at these sites. The aim of this study was to report the prevalence and spectrum of...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24050
更新日期:2018-10-01 00:00:00
abstract::We report an extremely rare case of skin collision tumor between primary Merkel cell carcinoma (MCC) and chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) first diagnosed on ultrasound-guided fine-needle aspiration biopsy (US-FNA). A 95-year-old female with a history of CLL presented with a slow growin...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23127
更新日期:2015-01-01 00:00:00
abstract::The study was carried out by the Human Reproduction Research Centre of the Indian Council of Medical Research at Lucknow and Kanpur, India as part of a multicenter study to ascertain the oncogenic potential of Norplant-I, a progestational contraceptive, by periodic cytological evaluation of cervical smears. In total, ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,多中心研究
doi:10.1002/dc.10326
更新日期:2003-09-01 00:00:00
abstract::Lymphoma involving serous effusion is uncommon. The diagnosis of effusion lymphoma may be challenging, particularly when the lymphoid cells are small to medium-sized, which would be difficult for differentiating reactive effusions from low grade lymphomas. Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL)...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24690
更新日期:2021-01-02 00:00:00
abstract::Fine-needle aspiration biopsies from three patients with neuroblastoma were studied by light microscopy, and the morphologic findings were correlated with those from transmission and scanning electron microscopy. Light microscopic examination of the aspiration smears from all three cases revealed small and large round...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840040410
更新日期:1988-01-01 00:00:00
abstract::While metastatic tumors to bone or lymph nodes from previously known primaries are often successfully diagnosed via fine-needle aspiration (FNA), a metastatic deposit in a patient with no previously known cancer may pose a diagnostic dilemma. Here, we present a case of metastatic papillary thyroid carcinoma that prese...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23031
更新日期:2014-08-01 00:00:00
abstract::Most granulomas of the prostate are nonspecific; infectious, post-operative, and allergic lesions are much less common. Fine-needle aspiration findings in the typical case are distinctive and easily recognized. Several series have been reported, but few have included histologic follow-up. We describe three cases of gr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840070513
更新日期:1991-01-01 00:00:00
abstract::Chondroid syringoma (CS) is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. In the present literature, reports of the cytologic appearance of CS are scarce as it is rarely encountered by fine needle aspiration (FNA)....
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23424
更新日期:2016-04-01 00:00:00
abstract::Primary pancreatic leiomyosarcomas are rare tumors of the pancreas that are usually diagnosed after resection or by biopsy. One case in the literature has utilized endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology. We report a second case of a primary pancreatic leiomyosarcoma that yielded diagnos...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23540
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder of B cell origin, and uncommonly it affects the lymph node. Fine needle aspiration cytology (FNAC) of lymph node of HCL has rarely been described. CASE DESCRIPTION AND DIAGNOSIS:A 41-year-old man presented with pallor, fever, tachycardia, gen...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24627
更新日期:2020-10-01 00:00:00
abstract::Microfilariae of various nematodes, including Loa loa, Dirofilariae, and Onchocerca volvulus, have been identified in the central nervous system (CNS). The CNS, however, is a rare site for the isolation of microfilariae of Wuchereria bancrofti. To the best of our knowledge, the presence of microfilariae of W. bancroft...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10074
更新日期:2002-03-01 00:00:00
abstract::Pancreatoblastoma is a rare tumor and has been reported only four times in the cytologic literature, three times in fine-needle aspiration (FNA) biopsy and once in an imprint of resected tumor. We are reporting the fourth case of FNA cytology with immunohistochemical and electron microscopic studies. The patient is a ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.20355
更新日期:2005-10-01 00:00:00
abstract::Recent therapeutic progresses in nonsmall cell lung cancer (NSCLC) and in colorectal cancer (CRC) are based on agents that specifically target the epidermal growth factor receptor (EGFR). To identify the patients most likely to benefit from such therapies, EGFR or KRAS gene mutation tests are mandatory, respectively, ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21512
更新日期:2011-09-01 00:00:00
abstract::Sebaceous lymphadenoma (SLA) is a histologic variant of lymphadenoma or sebaceous adenoma of the salivary gland. The fine-needle aspiration (FNA) cytology of SLA has not been well-described. In this report, we reported a case that involved an 81-year-old male with a long-standing left parotid mass and was diagnosed on...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23081
更新日期:2014-11-01 00:00:00
abstract::Malignant small round cell tumors represent a diagnostic challenge for cytologists and pathologists. This case series describes four cases of unusual metastasis of small round cell tumors subtypes into body cavities generating effusions in which fluid cytological examination suggested the neuroendocrine origin of the ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21771
更新日期:2013-04-01 00:00:00
abstract::In this report we describe the cytologic features of an unusual thymic carcinoid tumor containing prominent cytoplasmic lipid vacuoles that was diagnosed by fine-needle aspiration biopsy. The tumor presented as a presternal subcutaneous mass in an 81-yr-old female, with a contiguous mediastinal mass on computed tomogr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2020
更新日期:2001-08-01 00:00:00