Abstract:
:Acinar cell carcinoma (ACC) and islet cell tumor (ICT), both rare pancreatic neoplasms, can be diagnosed accurately and rapidly with the use of imaging-guided fine-needle aspiration biopsies. The specific cytologic features of these tumors are described in a series of 17 patients, and histologic and immunocytochemical correlations are discussed. Important cytologic findings in ACC are loosely cohesive clusters with cells having uniform nuclei and prominent nucleoli, cytoplasm is finely granular and eosinophilic. Islet cell tumors show many single cells, occasional rosettes, uniform nuclei, sometimes binucleate, dense basophilic cytoplasm. Chromogranin is often positive (80%) in ICT. Trypsin and chymotrypsin were often positive (71%) in ACC. Histology was confirmatory in all cytology cases. The recognition of cytologic features in conjunction with immunocytochemical studies can increase the diagnostic sensitivity for these two rare tumors.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Labate AM,Klimstra DL,Zakowski MFdoi
10.1002/(sici)1097-0339(199702)16:2<112::aid-dc3>3subject
Has Abstractpub_date
1997-02-01 00:00:00pages
112-6issue
2eissn
8755-1039issn
1097-0339pii
10.1002/(SICI)1097-0339(199702)16:2<112::AID-DC3>3journal_volume
16pub_type
杂志文章abstract:BACKGROUND:Cases with abnormal category, determined by thyroid fine-needle aspiration (FNA), frequently undergo surgical resection, despite the majority of cases being identified as benign after resection. Additional diagnostic markers are needed to guide the management of patients with abnormal thyroid nodules. MATER...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24394
更新日期:2020-06-01 00:00:00
abstract::During a ten year period, since we introduced needle aspiration cytology at our institution, we have diagnosed five cases of umbilical metastasis (Sister Mary Joseph's nodule). In none of the cases was any false negative or false positive diagnosis rendered and the primary carcinoma was found below the diaphragm. In a...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840100206
更新日期:1994-01-01 00:00:00
abstract::Malignant renal neoplasms are common solid tumors in pediatric oncology practice. These include the common Wilms' tumor/nephroblastoma and the uncommon neoplasms such as clear-cell sarcoma of the kidney (CCSK), rhabdoid tumor, renal-cell carcinoma, and others. The aim of this study was to describe in detail the cytopa...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20242
更新日期:2005-05-01 00:00:00
abstract::A single a case of malignant triton tumor, presented as a neck mass in a 34 year old female diagnosed solely by fine needle aspiration, is reported. The diagnosis was supported by immunohistochemical staining and electron microscopic examination that showed evidence of both schwannian and rhabdomyoblastic differentiat...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0339(199612)15:5<435::AID-DC16>
更新日期:1996-12-01 00:00:00
abstract::Sebaceous lymphadenoma (SLA) is a histologic variant of lymphadenoma or sebaceous adenoma of the salivary gland. The fine-needle aspiration (FNA) cytology of SLA has not been well-described. In this report, we reported a case that involved an 81-year-old male with a long-standing left parotid mass and was diagnosed on...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23081
更新日期:2014-11-01 00:00:00
abstract::Juvenile xanthogranuloma (JXG) is a rare type of non-Langerhan cell histiocytic disorder, which is mostly confined to skin of head and neck. It is a self-limiting benign condition, which does not require surgery. We present a case of 8-month-old girl child with multiple yellowish brown colored papules over scalp, face...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24310
更新日期:2020-01-01 00:00:00
abstract::The largest series, to date, of fine-needle aspiration cytology (FNAC) findings in clear-cell sarcoma of the kidney (CCSK) is presented. All fine-needle aspirates of pediatric renal masses over a 17-yr period were reviewed. Eight out of 119 aspirates from late-stage childhood renal tumors (6.72%) were found to be CCSK...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20317
更新日期:2005-08-01 00:00:00
abstract::The presence of malignant pleural effusion in patients with non-small cell bronchogenic cancer has a poor prognostic significance and is indicative of advanced disease (T4, IIIB). The present study will investigate the role of cytology and identify the various cellular components seen in thoracic washings, in the abse...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(200004)22:4<218::aid-dc3>3
更新日期:2000-04-01 00:00:00
abstract::In the absence of previously documented sarcoma, the initial diagnosis of angiosarcoma (AS) on fine-needle aspiration (FNA) biopsy of the liver is difficult. However, awareness of its occurrence and the assistance of immunocytochemical stains may aid in arriving at the correct diagnosis. In this paper, a 59-yr-old smo...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199803)18:3<208::aid-dc9>3
更新日期:1998-03-01 00:00:00
abstract::Many reports have been published on the accuracy of the cervical vaginal smear for squamous lesions, and the literature contains fewer reports on the accuracy of the cervical vaginal smear for glandular lesions. The sensitivity of glandular lesion diagnosis depends on the subtype of lesion. The diagnostic sensitivity ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/1097-0339(200008)23:2<127::aid-dc13>3.0.co
更新日期:2000-08-01 00:00:00
abstract::Adenoid cystic carcinoma (ACC) is a malignant neoplasm most commonly originating in salivary glands of the head and neck area. When ACC presents outside of these locations, the diagnosis may become more challenging. We describe three cases of ACC presenting in extra-salivary gland sites. Two cases were metastatic; in ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20500
更新日期:2006-07-01 00:00:00
abstract::Epithelioid angiosarcomas are extremely rare tumors associated with poor prognosis and early metastases. Its epithelioid cytomorphology and limited vasoformation make it difficult to distinguish from more common malignancies, such as, carcinoma. This can be a potential diagnostic pitfall for the cytopathologist. In th...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21187
更新日期:2010-02-01 00:00:00
abstract::Ciliated muconodular papillary tumors (CMPTs) of the lung are rare, likely benign neoplastic lesions. Here we describe a case of a CMPT, focusing on its cytologic features, which to our knowledge have not been reported previously. Owing to dull back pain, a 69-year-old male non-smoker underwent CT, which revealed a 1....
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24169
更新日期:2019-07-01 00:00:00
abstract::Adamantinoma-like Ewing Sarcoma (ALES) is a rare subtype of Ewing sarcoma family of tumors (EFTs) which are defined by their EWSR1 gene rearrangements. We present a case of a 15-year old female with a swelling in her anterior neck of 4 months duration which had recently begun to rapidly grow in size. Fine needle aspir...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24467
更新日期:2020-05-30 00:00:00
abstract::Occupational asbestos exposure is believed to be the primary etiologic link to mesothelioma. However, in the evaluation of familial mesothelioma, it is important to consider the possibility of household exposure to asbestos. In this study, we report a family in which the father with prolonged occupational asbestos exp...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21859
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Intraperitoneal malignant cells detection in patients with gastric cancer is associated with a significant decrease in overall survival. The overall accuracy of cytological examination of peritoneal lavages, however, is quite low, and intraperitoneal recurrence has been observed even in patients with negativ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24165
更新日期:2019-07-01 00:00:00
abstract::The use of ultrasound-guided fine-needle aspiration (FNA) biopsy for nonpalpable breast lesions varies considerably. This retrospective study stresses the role of breast FNA in evaluating sonographically suspicious nonpalpable breast masses using a probabilistic reporting system. One hundred and eight consecutive ultr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20068
更新日期:2004-05-01 00:00:00
abstract::Extra-pulmonary tuberculosis is the presence of disease in an organ without obvious involvement of the lungs (World Health Organization, Tuberculosis Fact sheet, 2006). The present article focuses on the incidence of extra-pulmonary tuberculosis as an emerging and clinically significant disease to be reckoned with in ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.22827
更新日期:2013-05-01 00:00:00
abstract::Metastatic carcinoma to the pancreas is uncommon and head and neck squamous carcinoma metastatic to the pancreas is extremely rare. Metastatic squamous cell carcinoma to the pancreas presents a unique diagnostic challenge: in addition to mimicking the rare primary squamous cell carcinoma of the pancreas based on cytol...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23769
更新日期:2017-11-01 00:00:00
abstract::Mites were observed in 55 pulmonary specimens examined routinely over a 4.5-yr period. The 55 specimens included 33 spontaneous and 12 aerosol-induced sputum samples, nine bronchial washings, and one fine-needle aspirate. Two specimens contained only fragments of mites; however, in most cases the mites were relatively...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840050416
更新日期:1989-01-01 00:00:00
abstract::Disseminated histoplasmosis (DH) is a systemic granulomatous disease caused by the fungus Histoplasma capsulatum. This disease occurs mainly in immunocompromised individuals with CD 4 counts less than 200 cell/µL and is rarely noted in immunocompetent person. In India, this disease has been reported from several parts...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23742
更新日期:2017-09-01 00:00:00
abstract::Benign and malignant papillary lesions of the breast (PBL) can be difficult to distinguish in fine-needle aspirates (FNA). This study evaluates the use of smooth muscle actin (SMA) and a new smooth muscle-specific protein, calponin, for identifying myoepithelial cells (MEC) by immunohistochemical methods in paraffin-e...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/1097-0339(200009)23:3<151::aid-dc2>3.0.co;
更新日期:2000-09-01 00:00:00
abstract::Cystic nephromas are rare tumors of the kidney most commonly affecting boys or adult females. The fine-needle aspiration cytomorphology has not yet been described. A renal cystic mass in a 56 year old female was aspirated under ultrasound guidance. Papanicolaou stained smears of the cyst fluid revealed markedly atypic...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840080408
更新日期:1992-01-01 00:00:00
abstract::Salivary duct carcinoma (SDC) is an extremely rare and highly aggressive primary epithelial neoplasm of the salivary glands associated with increased tendency for lymph node and vascular metastases. Histologically, this lesion resembles intraductal cribriform and comedo carcinoma of the breast. Fine-needle aspiration ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840110111
更新日期:1994-01-01 00:00:00
abstract::Cell blocks (CBs) are often prepared with fine-needle aspirates (FNAs) from multiple organs as an adjunct to smears in the diagnosis of aspirated lesions. However, the literature contains few reports on their utility with regard to specific organ sites. At our institution, CBs are made routinely on FNAs when there is ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20385
更新日期:2006-02-01 00:00:00
abstract::From 1,488 patients, satisfactory sputum was available for cytologic diagnosis. Overall diagnoses were correct in 85.4% of patients, false negative in 193 patients (13.0%), and false positive in 24 patients (1.6%). In patients with a malignant lung process, cytologic diagnoses were correct in 228 patients (54.2%) and ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840010406
更新日期:1985-10-01 00:00:00
abstract::Acute myeloid leukemia (AML) is the fifth most common malignancy in children. Extramedullary involvement in acute myeloid leukemia is rare and can be seen in soft tissues, central nervous system, skin and lymphoreticular organs. The clinical presentations can often be non-specific and hence, the diagnosis can be very ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24649
更新日期:2020-10-23 00:00:00
abstract:BACKGROUND:The 2012 American Society for Colposcopy and Cervical Pathology Consensus Guidelines provide information for managing abnormal cervical cancer screening tests and cancer precursors. According to these guidelines for Pap smear diagnosis of Atypical squamous cells of undetermined significance, reflex high risk...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24158
更新日期:2019-07-01 00:00:00
abstract::Warthin-like papillary thyroid carcinoma (WLPTC) is a rare morphological variant of papillary thyroid carcinoma which mimics various benign and malignant lesions on thyroid aspiration cytology. As correct cytological diagnosis is the cornerstone for appropriate patient management, awareness of the salient cytomorpholo...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23739
更新日期:2017-09-01 00:00:00
abstract::Pancreatic adenocarcinoma is a genetic disease showing somatic mutations of multiple genes, including SMAD4. SMAD4 is a tumor suppressor gene that is inactivated in a sub-set of pancreatic adenocarcinoma, either by the intragenic mutation of one allele in combination with the loss of the other allele or by homozygous ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20715
更新日期:2007-10-01 00:00:00