Abstract:
:In the absence of previously documented sarcoma, the initial diagnosis of angiosarcoma (AS) on fine-needle aspiration (FNA) biopsy of the liver is difficult. However, awareness of its occurrence and the assistance of immunocytochemical stains may aid in arriving at the correct diagnosis. In this paper, a 59-yr-old smoker and alcoholic woman presented after a syncopal episode and was found to have a palpable right abdominal mass. An abdominal CT scan confirmed multiple centrally necrotic liver masses, from which an FNA biopsy was obtained. The smears were bloody with groups of relatively dishesive and singly dispersed spindle cells in a somewhat necrotic background. The nuclei were elongated to ovoid-round with small nucleoli. The cytoplasm was ample and ill-defined. The cells were reactive for factor VIII-related antigen and CD31 but negative for cytokeratin immunocytochemical stains, and a diagnosis of "suspicious for angiosarcoma" was entertained. The patient declined further studies or treatment but presented 4 mo later with light-headedness and hypoglycemia. Laparoscopic tissue biopsies of the liver/abdominal masses were obtained and revealed AS. Rarely, liver masses may represent AS. Pathologists should be aware of their cytomorphology and characteristic immunostaining to avoid their misinterpretation.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Saleh HA,Tao LCdoi
10.1002/(sici)1097-0339(199803)18:3<208::aid-dc9>3subject
Has Abstractpub_date
1998-03-01 00:00:00pages
208-11issue
3eissn
8755-1039issn
1097-0339pii
10.1002/(SICI)1097-0339(199803)18:3<208::AID-DC9>3journal_volume
18pub_type
杂志文章abstract::We applied TdT-mediated deoxyuridine triphosphate (dUTP)-biotin nick end labeling (TUNEL) to cytologic smears in order to detect the cells undergoing apoptosis. These smears were obtained by scraping the cut surface of 9 cases of carcinoma, including renal-cell carcinoma (3 cases), esophageal squamous-cell carcinoma (...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199806)18:6<398::aid-dc3>3
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:GATA-3 is a transcription factor involved in human tissue growth and differentiation. It is a potential marker for breast carcinoma origin in metastasis and predictive of good prognosis. We aim to evaluate the role of GATA3 in determining the breast origin of metastatic adenocarcinoma in malignant effusions ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23521
更新日期:2016-09-01 00:00:00
abstract::Sequential tracheal aspirates from 39 neonates with hyaline membrane disease were examined to correlate cytological findings with the development of bronchopulmonary dysplasia (BPD). A total of 224 tracheal aspirates were examined from these infants, 15 of whom developed BPD as diagnosed by conventional clinical and r...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840020307
更新日期:1986-09-01 00:00:00
abstract::GATA binding protein 3 is a zinc finger transcription factor with high affinity for urothelial tissue and is a promising immunohistochemical marker in detection of urothelial carcinomas (UC). We studied its usefulness in metastatic high-grade UC. This study was performed on cell blocks (CB) of fine needle aspirates fr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23131
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:The essential of urine cytology for the diagnosis and the follow-up of urothelial neoplasia has been widely recognized. However, there are some cases in which a definitive diagnosis cannot be made due to difficulty in discriminating between benign and malignant. This study evaluated the practicality of nucle...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23469
更新日期:2016-06-01 00:00:00
abstract::Synovial sarcoma (SS) is one of the most common soft tissue tumors that typically presents in the extremities of young adults, but may occur at any site and affect children during the first decade. Herein we discuss a 12-yr-old male who complained of left foot pain and plantar mass. A fine-needle aspiration biopsy of ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20566
更新日期:2006-11-01 00:00:00
abstract::This study investigates the potential value of the nuclear matrix protein NMP179 as a marker of abnormal squamous cells in ThinPrep slides. Forty-six cervical scrapes were collected as cell suspensions and ThinPrep slides were prepared. They were double-immunostained for NMP179 and Cytokeratin 18 (CK18), an endocervic...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20061
更新日期:2004-09-01 00:00:00
abstract::Alzheimer's disease (AD) is the most common form of dementia. The cardinal histopathologic features include senile plaques (SPs) and neurofibrillary tangles (NFTs), and in addition, granulovacuolar degeneration (GVD) and Hirano bodies (HBs) are frequently observed in the hippocampus. We studied hippocampal cytological...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21053
更新日期:2009-09-01 00:00:00
abstract::Fine needle aspiration (FNA) is a valuable, noninvasive, commonly used technique in the diagnoses of head and neck tumors. Adult rhabdomyoma is a rare benign tumor of striate muscle tissue usually located in the head and neck region. Cytomorphologically, the tumor cells have eosinophilic finely granular cytoplasm, whi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21033
更新日期:2009-07-01 00:00:00
abstract::Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon, benign, inflammatory disorder involving the skin and microvasculature with an undetermined etiopathogenesis. Although the histopathology is well-characterized, the cytologic features of this entity have been rarely described in literature. This study w...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24563
更新日期:2021-01-01 00:00:00
abstract::Like a pulmonary counterpart, extrapulmonary small cell carcinoma (SCC) is an aggressive tumor with a high rate of metastasis. Forty-nine fine-needle aspiration biopsies (FNABs) (36 patients) of various primary sites other than the lung diagnosed as metastatic SCC (including Merkel cell carcinoma) were reviewed. FNABs...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199809)19:3<177::aid-dc4>3
更新日期:1998-09-01 00:00:00
abstract::Signet-ring lymphoma is a rare entity in which the synthesis or secretion of immunoglobulins is impaired, producing a signet-ring appearance to the lymphoma cells. A case of this type of lymphoma is described, and the cytologic aspects of the cells obtained from the fixative fluid are described. ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840020413
更新日期:1986-12-01 00:00:00
abstract::Alveolar soft part sarcoma (ASPS) is a rare, high-grade, epithelial-like sarcoma that shows characteristic histopathologic findings. Although a chromosomal anomaly that seems specific has been recently described, its diagnosis is based on histologic and ultrastructural features. The tumor shows no specific immunohisto...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10139
更新日期:2002-08-01 00:00:00
abstract::Intranuclear pseudoinclusions represent invaginations of the cytoplasm into the nucleus. The nuclear pseudoinclusions are generally easier to appreciate in cytological preparations than frozen sections or histopathology thus forming an important cytological feature. In the present article we have reviewed the morpholo...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21714
更新日期:2012-08-01 00:00:00
abstract::The identification of two cell populations displaying different cytologic characteristics in the same fine needle aspiration (FNA), one with an epithelioid appearance and the other spindle cell morphology, is an extremely rare phenomenon and potentially represents a source of diagnostic confusion. Depending on the lin...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24579
更新日期:2021-02-01 00:00:00
abstract::Fine-needle aspiration cytology (FNAC) is an acknowledged method for diagnosing prostate cancer. False-positive results are uncommon, but concerns have been raised that prostatic intraepithelial neoplasia (PIN) could be misinterpreted as carcinoma. Therefore, we attempted to describe cytological features of PIN. Cells...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20417
更新日期:2006-05-01 00:00:00
abstract::Genital tract tuberculosis is usually secondary to an extragenital tubercular focus. Cervical tuberculosis, however, is rare accounting for up to 3% of all genital tract diseases. The diagnosis of tuberculosis is usually established on multiple cervical biopsies followed by bacteriological confirmation. There are only...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21082
更新日期:2009-08-01 00:00:00
abstract::Five cases of mammary Paget's disease were diagnosed by nipple scrape cytology. The neoplastic material obtained was abundant in two cases, moderate in one, but in two, only a few cell aggregates feature in three cases and this, together with dense tumour cell cytoplasm and the background of keratinous debris, may imp...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840090309
更新日期:1993-01-01 00:00:00
abstract::Lymphomas presenting in effusions could either be primary or secondary, with very limited data from Taiwan. METHODS:We retrospectively reviewed effusion lymphomas from our archives in a tertiary center from July 2011 to June 2019. RESULTS:We identified 59 specimens from 43 patients, including 7 cases with primary ef...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24626
更新日期:2021-02-01 00:00:00
abstract::Chondroid syringoma is a rare benign skin adnexal tumor of eccrine/apocrine origin affecting commonly the head and neck region. It used to be previously called as mixed tumor of skin because of the presence of both the epithelial and mesenchymal components. There are only few case reports describing the fine needle as...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21159
更新日期:2010-01-01 00:00:00
abstract::The present study sought possible factors leading to the cytological diagnosis of atypical squamous cells of uncertain significance (ASCUS) in cases of high-grade squamous intraepithelial lesions (HSIL). Based on retrospective histopathological analysis of loop electrical excision procedure (LEEP) products that diagno...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10035
更新日期:2002-01-01 00:00:00
abstract::Asbestos pollution is a global problem. Asbestos exposure induced mesothelioma does not require an 'occupational' type of exposure. Bystander exposures may result in earlier age of disease onset and more aggressive disease progression as described in the following 3 case reports. ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20766
更新日期:2007-12-01 00:00:00
abstract::Anaplastic large-cell lymphoma (ALCL) is a rare T-cell lymphoma typically seen in children and young adults. It has been described in numerous sites; however, the breast is one of the least common locations. We herein report a case of ALCL arising in the breast of a 36-yr-old pregnant woman. To our knowledge this is t...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20442
更新日期:2006-04-01 00:00:00
abstract::Serous tubal intraepithelial carcinoma (STIC) has attracted attention as a precursor lesion of high-grade serous carcinoma (HGSC) of the ovary. We report the rare case of a woman in whom adenocarcinoma cells were detected in cervical smears and demonstrated to be derived from STIC in the fimbria. The patient was a 48-...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23957
更新日期:2018-11-01 00:00:00
abstract::The presence of pericellular lacunae has been cited as a useful criterion in distinguishing between benign and malignant effusions from body cavities. This study assessed the presence of pericellular lacunae in 75 specimens of malignant and 38 specimens of benign effusions. In a large number of cases, lacunae could no...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0339(199609)15:3<193::AID-DC4>3
更新日期:1996-09-01 00:00:00
abstract::Telomerase is inactive in most somatic cells, but has been found to be reactivated in a majority of cancers. Our principal goal was to test whether the presence of telomerase activity concurred with positive cytology, and was thus of potential use in detecting cancer cells in effusions. The telomeric repeat amplificat...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/1097-0339(200103)24:3<174::aid-dc1036>3.0.
更新日期:2001-03-01 00:00:00
abstract::The cytologic diagnosis of papillary thyroid carcinoma is straightforward in most instances. However, there are some mimics including goitrous nodules and Hurthle cell neoplasms. Many studies have shown the combination of HBME-1 and CK19 expression to be useful in reaching a correct histologic diagnosis on tissue sect...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20841
更新日期:2008-08-01 00:00:00
abstract:INTRODUCTION:The incidence of thyroid cancer is increasing which can be attributed in part to improved ultrasonography (US) methods and increased detection of incidental thyroid carcinomas (ITC). We aimed to compare ITC with nonincidental thyroid carcinomas (NITC) in this study. METHODS:Retrospective analyses of 906 i...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24117
更新日期:2019-05-01 00:00:00
abstract::The risk of malignancy for some diagnoses in thyroid fine-needle aspirations is higher than the actual risk of clinical progression. Other measures of prognosis may be helpful in managing patients with indeterminate thyroid fine-needle aspiration diagnoses. We estimated the risk of death due to disease (RDDD) for well...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24254
更新日期:2019-10-01 00:00:00
abstract::A series of 85 fine-needle aspiration (FNA) biopsies from orbital space occupying lesions of 82 patients are reviewed. A total of 32 benign lesions and 49 malignant lesions were conclusively diagnosed. In two cases the aspirates were insufficient for diagnosis. Of two cases, which were cytologically suspicious for lym...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20375
更新日期:2006-01-01 00:00:00