Pericellular lacunae in the diagnosis of metastatic carcinoma in effusions: is this a useful sign?

Abstract:

:The presence of pericellular lacunae has been cited as a useful criterion in distinguishing between benign and malignant effusions from body cavities. This study assessed the presence of pericellular lacunae in 75 specimens of malignant and 38 specimens of benign effusions. In a large number of cases, lacunae could not be assessed reliably because of technical and artifactual reasons. Pericellular lacunae were detected around the majority of the cell clusters in only 4 of the malignant and 2 of the benign cases. In our material, pericellular lacunae were not a useful criterion for the diagnosis of malignancy in body cavity fluids.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Thomson T,Hayes MM

doi

10.1002/(SICI)1097-0339(199609)15:3<193::AID-DC4>3

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

193-6

issue

3

eissn

8755-1039

issn

1097-0339

pii

10.1002/(SICI)1097-0339(199609)15:3<193::AID-DC4>3

journal_volume

15

pub_type

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