Familial mesothelioma in first degree relatives.

Abstract:

:Occupational asbestos exposure is believed to be the primary etiologic link to mesothelioma. However, in the evaluation of familial mesothelioma, it is important to consider the possibility of household exposure to asbestos. In this study, we report a family in which the father with prolonged occupational asbestos exposure developed malignant pleural mesothelioma and his daughter 14 years later mesothelioma in situ with focally early invasion. Several reports of familial aggregations of mesothelioma strongly support that genetic factors in collaboration with environmental exposure may contribute etiologically to an as yet unknown fraction of occurrence of this disease.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Kalogeraki AM,Tamiolakis DJ,Lagoudaki ED,Papadakis MN,Papadakis GZ,Agelaki SI,Stathopoulos EN,Tzardi MN

doi

10.1002/dc.21859

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

654-7

issue

7

eissn

8755-1039

issn

1097-0339

journal_volume

41

pub_type

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