Can glandular lesions be diagnosed in pap smear cytology?

Abstract:

:Many reports have been published on the accuracy of the cervical vaginal smear for squamous lesions, and the literature contains fewer reports on the accuracy of the cervical vaginal smear for glandular lesions. The sensitivity of glandular lesion diagnosis depends on the subtype of lesion. The diagnostic sensitivity is highest for invasive endocervical adenocarcinoma and lowest for endometrial adenocarcinoma. The ability of some of the Bethesda system categories for glandular lesions to describe what they purport to describe is questionable. The Bethesda system categories of adenocarcinoma accurately classify adenocarcinomas. The Bethesda System category of atypical glandular cells of undetermined significance (AGUS) is a misnomer. Although many cases of adenocarcinoma in-situ are placed in this category, follow-up of patients with AGUS show that the majority of patients with clinically significant lesions have squamous dysplasias. Other categories of AGUS, such as AGUS favor endometrial origin, are more appropriately named and encompass endometrial lesions which are either neoplastic or non-neoplastic.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Raab SS

doi

10.1002/1097-0339(200008)23:2<127::aid-dc13>3.0.co

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

127-33

issue

2

eissn

8755-1039

issn

1097-0339

pii

10.1002/1097-0339(200008)23:2<127::AID-DC13>3.0.CO

journal_volume

23

pub_type

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