Cytological diagnosis of juvenile xanthogranuloma: A rare histiocytic disorder.

Abstract:

:Juvenile xanthogranuloma (JXG) is a rare type of non-Langerhan cell histiocytic disorder, which is mostly confined to skin of head and neck. It is a self-limiting benign condition, which does not require surgery. We present a case of 8-month-old girl child with multiple yellowish brown colored papules over scalp, face, and neck. A clinical diagnosis of cutaneous mastocytosis was made. Fine-needle aspiration cytology (FNAC) smears showed foamy macrophages along with mixed inflammatory infiltrate and few touton giant cells. A diagnosis of JXG was rendered which was confirmed on histopathology and immunohistochemistry.Juvenile xanthogranuloma can be diagnosed on FNAC based on its characteristic cytologic features; however, it requires a high index of suspicion by cytopathologist. Cytological diagnosis of JXG can save the patient from unnecessary surgical biopsy or excision.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Chauhan S,Diwaker P,Singh A,Gogoi P,Arora VK

doi

10.1002/dc.24310

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

66-70

issue

1

eissn

8755-1039

issn

1097-0339

journal_volume

48

pub_type

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