Abstract:
:Yeast chromosomes terminate in tracts of simple repetitive DNA (poly[G1-3T]). Mutations in the gene TEL1 result in shortened telomeres. Sequence analysis of TEL1 indicates that it encodes a very large (322 kDa) protein with amino acid motifs found in phosphatidylinositol/protein kinases. The closest homolog to TEL1 is the human ataxia telangiectasia gene.
journal_name
Celljournal_title
Cellauthors
Greenwell PW,Kronmal SL,Porter SE,Gassenhuber J,Obermaier B,Petes TDdoi
10.1016/0092-8674(95)90479-4subject
Has Abstractpub_date
1995-09-08 00:00:00pages
823-9issue
5eissn
0092-8674issn
1097-4172pii
0092-8674(95)90479-4journal_volume
82pub_type
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