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Insulin-like growth factor I (IGF-I) affects plasma lipid profile and inhibits the lipolytic action of growth hormone (GH) in isolated adipocytes.

Abstract：

:The actions of insulin-like growth factor I (IGF-I) and growth hormone (GH) on lipid metabolism have been investigated in hormonally intact rats. The subcutaneous injection of IGF-I (100 micrograms) and GH (100 micrograms) lowered total cholesterol plasma levels. The in vitro assays on isolated rat adipocytes showed an antilipolytic effect of IGF-I on GH induced lipolysis. All these data support an important role for IGF-I and GH on the regulation of lipid metabolism.

journal_name

Life Sci

journal_title

Life sciences

authors

Pascual M,Larralde J,Martínez JA

doi

10.1016/0024-3205(95)02067-s

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

1213-8

issue

12

eissn

0024-3205

issn

1879-0631

pii

002432059502067S

journal_volume

57

pub_type

杂志文章

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