Abstract:
:In this high resolution magnetic resonance spectroscopic study of experimental allergic encephalomyelitis (EAE) and Semliki Forest virus (SFV) infection of the Biozzi AB/H mouse, marked increases in the initially low levels of N-trimethyl compounds in the spinal cord were observed during probable demyelinating episodes. There was also a pronounced and reproducible modulation of the levels of taurine and myo-inositol during acute and again during chronic relapsing EAE. The ratio of N-acetyl-aspartate to creatine in the spinal cord of mice infected with the mutant M9 strain of SFV decreased to approximately 70% of that seen in normal mice.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Preece NE,Amor S,Baker D,Gadian DG,O'Neill JK,Urenjak Jdoi
10.1002/mrm.1910320603subject
Has Abstractpub_date
1994-12-01 00:00:00pages
692-7issue
6eissn
0740-3194issn
1522-2594journal_volume
32pub_type
杂志文章abstract:PURPOSE:To verify MR measurements of myocardial extracellular volume fraction (ECV) based on clinically applicable T1-mapping sequences against ECV measurements by radioisotope tracer in pigs and to relate the results to those obtained in volunteers. METHODS:Between May 2016 and March 2017, 8 volunteers (25 ± 4 years,...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27938
更新日期:2020-02-01 00:00:00
abstract::We have developed a method for measuring the electrocardiogram (ECG) continuously during MR examinations. In contrast to ECG acquisition by wires, our new method is to amplify and convert the ECG into an optical signal directly above the patient's heart. The optical signal is transmitted out of the magnet bore by opti...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910320416
更新日期:1994-10-01 00:00:00
abstract::Electron paramagnetic resonance imaging using nitroxides is a powerful method for visualizing the redox status modulated by oxidative stress in vivo. Typically, however, data acquisition times have been too slow to obtain a sufficient number of projections for three-dimensional images, when using continuous wave-elect...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22598
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To study the feasibility of black-blood contrast in native T1 mapping for reduction of partial voluming at the blood-myocardium interface. METHODS:A saturation pulse prepared heart-rate-independent inversion recovery (SAPPHIRE) T1 mapping sequence was combined with motion-sensitized driven-equilibrium (MSDE) b...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26378
更新日期:2017-08-01 00:00:00
abstract::The magnetization subtraction technique (MS), which is equivalent to the inversion recovery technique in strong magnetic fields, has been implemented in dynamic nuclear polarization-enhanced magnetic resonance imaging (DNPI). The general theoretical basis of the MS method, which can be applied to DNPI or to prepolariz...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910350316
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the feasibility of in vivo imaging of human pancreatic ductal cells by OATP1B3 reporter gene under MRI. METHODS:A human cell line (PANC-1) derived from the pancreatic ductal epithelium was used in this study. After transduction of OATP1B3, the cellular physiological...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27749
更新日期:2019-08-01 00:00:00
abstract::A deficit of fatty alcohol:NAD+ oxidoreductase complex (FAO) activity has been detected in patients with the Sjögren-Larsson syndrome (SLS). A moderate decrease in FAO activity has also been reported in heterozygote SLS subjects. Abnormal peaks were detected with proton magnetic resonance spectroscopy (1H-MRS) in homo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1146
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:Single-scan two-dimensional MRI has been generally constrained to acquisitions in high quality magnets. This study introduces a methodology, cross-term spatiotemporal encoding (xSPEN), that delivers such images under much poorer external field conditions. METHODS:xSPEN departs from conventional k-space scannin...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26145
更新日期:2017-02-01 00:00:00
abstract::This work helps elucidate how background noise introduces statistical artifacts in the distribution of the sorted eigenvalues and eigenvectors in diffusion tensor MRI (DT-MRI) data. Although it was known that sorting eigenvalues (principal diffusivities) by magnitude introduces a bias in their sample mean within a hom...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/1522-2594(200007)44:1<41::aid-mrm8>3.0.co;
更新日期:2000-07-01 00:00:00
abstract::A high frequency solution of the electromagnetic field produced by a circular surface coil adjacent to a homogeneous conducting, dielectric sphere is used to predict the attainable signal to noise ratio (S/N) and specific absorption rate (SAR) for in vivo 1H NMR spectroscopy experiments from 200 to 430 MHz (4.7-10 T)....
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910220254
更新日期:1991-12-01 00:00:00
abstract::Magnetization exchange effects between the matrix macromolecules (e. g., collagen and proteoglycan) and water were examined in normal, deuterated, and proteoglycan-depleted articular cartilage. Relaxation results (T(2), T(1rho), and T(1)) suggested that a four-site exchange scheme provided an accurate model for articu...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/1522-2594(200012)44:6<840::aid-mrm4>3.0.co
更新日期:2000-12-01 00:00:00
abstract::Activity-induced manganese-dependent contrast (AIM) MRI is a hemodynamic-independent functional MRI method that used manganese ion as an MR-detectable contrast agent. In AIM, MnCl(2) is infused intra-arterially after the blood-brain barrier (BBB) is opened with a hyperosmolar agent. Upon functional stimulation of the ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10320
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:Establishing a framework to evaluate performances of prospective motion correction (PMC) MRI considering motion variability between MRI scans. METHODS:A framework was developed to obtain quantitative comparisons between different motion correction setups, considering that varying intrinsic motion patterns betw...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25580
更新日期:2016-02-01 00:00:00
abstract::Generalized MR interferography allows the measurement of parameters which affect the phase of the MR signal. Interference is generated by the simultaneous generation of two echoes in one excitation cycle. Local variations of the signal phase are transformed into displacement of the stripe pattern generated by interfer...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910160305
更新日期:1990-12-01 00:00:00
abstract::It is shown that the effect of pH changes can be measured in proton NMR spectra through the pH sensitivity of the signal intensities of metabolite protons exchanging with water. To observe this phenomenon, pulse sequences must be used that can sensitively observe these exchangeable protons under physiological conditio...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910400105
更新日期:1998-07-01 00:00:00
abstract::We present preliminary results for a 3D finite element calculation to evaluate RF penetration in conducting dielectric materials at high field strengths. A tetrahedral mesh is used along with a Coulomb gauge constraint in a finite element method that yields excellent numerical stability at high frequencies. Accuracy i...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910300315
更新日期:1993-09-01 00:00:00
abstract:PURPOSE:Simultaneous brain and spinal cord functional MRI is emerging as a new tool to study the central nervous system but is challenging. Poor B0 homogeneity and small size of the spinal cord are principal obstacles to this nascent technology. Here we extend a dynamic shimming approach, first posed by Finsterbusch, b...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.27388
更新日期:2019-02-01 00:00:00
abstract::The chemical shift of water and fat resonances in proton MRI allows separation of water and fat signal from chemical shift encoded data. This work describes an automatic method that produces separate water and fat images as well as quantitative maps of fat signal fraction and T2* from complex multiecho gradient-recall...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.23185
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To obtain three-dimensional (3D) MR angiography having high contrast between vessel and stationary background tissue, a novel technique called sliding time of flight (TOF) is proposed. METHODS:The proposed method relies on the property that flow-related enhancement (FRE) is maximized at the blood-entering slic...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25215
更新日期:2015-03-01 00:00:00
abstract::The concept of temporal echo multiplexing is defined and used to develop rapid biphasic spin-echo sequences for imaging the heart. Three imaging sequences, based on four-echo and two-echo multiplexing and rapid single echo (i.e., conventional spin-echo imaging), are compared. Preliminary results indicate that two-echo...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910110109
更新日期:1989-07-01 00:00:00
abstract::Single-slab 3D turbo/fast spin echo (SE) imaging with very long echo trains was recently introduced with slab selection using a highly selective excitation pulse and short, nonselective refocusing pulses with variable flip angles for high imaging efficiency. This technique, however, is vulnerable to image degradation ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22070
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:To improve quantification of myocardial blood flow using a fast T1 mapping technique using highly constrained back projection reconstruction (HYPR)-accelerated acquisition. METHODS:A major source of error in the measurement of myocardial blood flow (MBF) using MRI is the nonlinear relationship between image si...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.24958
更新日期:2014-09-01 00:00:00
abstract::Conventional approaches for MR elastography (MRE) using surface drivers have difficulty achieving sufficient shear wave propagation in the prostate gland due to attenuation. In this study we evaluate the feasibility of generating shear wave propagation in the prostate gland using a transurethral device. A novel transu...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.22038
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:The purpose of the present study was to apply noninvasive methods for monitoring regeneration and mechanical properties of tissue-engineered cartilage in vivo at different growth stages using MR elastography (MRE). METHODS:Three types of scaffolds, including silk, collagen, and gelatin seeded by human mesenchy...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.25745
更新日期:2016-03-01 00:00:00
abstract::SENSitivity Encoding (SENSE) greatly enhances the quality of diffusion-weighted echo-planar imaging (EPI) by reducing blurring and off-resonance artifacts. Such improvement would also be desirable for diffusion tensor imaging (DTI), but measures derived from the diffusion tensor can be extremely sensitive to any kind ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.10184
更新日期:2002-07-01 00:00:00
abstract:PURPOSE:MRI can produce quantitative liver fat fraction (FF) maps noninvasively, which can help to improve diagnoses of fatty liver diseases. However, most sequences acquire several two-dimensional (2D) slices during one or more breath-holds, which may be difficult for patients with limited breath-holding capacity. A w...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.26028
更新日期:2016-11-01 00:00:00
abstract::In vivo MR spectroscopy (MRS) studies have shown reductions in NAA/Cr levels in patients with severe neurocognitive deficits due to AIDS dementia complex (ADC), also known as neuroAIDS. The relationship between the cellular changes within the brain during neuroAIDS and the role of NAA/Cr as a metabolic marker remains ...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.21556
更新日期:2008-03-01 00:00:00
abstract::The relaxation of (1)H nuclei due to their interaction with quadrupolar (14)N nuclei in gel structures is measured using fast field-cycling NMR. This phenomenon called quadrupolar dips has been reported in different (1)H-(14)N bond-rich species. In this study, we have studied quadrupolar dips in fibrin, an insoluble p...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.23117
更新日期:2012-05-01 00:00:00
abstract::The apparent diffusion coefficient (ADC) in the optic nerve was measured from diffusion-weighted magnetic resonance imaging using an intravoxel incoherent motion (IVIM) sequence. The subjects were seven normal volunteers and eight patients with multiple sclerosis (MS) with a total of four optic nerves with acute neuri...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/mrm.1910380317
更新日期:1997-09-01 00:00:00
abstract::The incorporation of RF coils into the tips of intravascular devices has been shown to enable the localization of catheters and guidewires under MR guidance. Furthermore, such coils can be used for endoluminal imaging. The long cable required to connect the coil with the scanner input inadvertently acts as a dipole an...
journal_title:Magnetic resonance in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1522-2594(200004)43:4<615::aid-mrm19
更新日期:2000-04-01 00:00:00