Construction of recombinant avian infectious laryngotracheitis virus expressing the beta-galactosidase gene and DNA sequencing of the insertion region.

abstract：:Recently, we reported that PrP(Sc), a surrogate marker for prion disease, is associated with the cellular fraction of blood from scrapie-infected sheep using a ligand-based immunoassay. In the study reported here, we found that a subset of peripheral blood mononuclear cells is most likely to sequester PrP(Sc) during b...

journal_title：Virology

authors： Edwards JC,Moore SJ,Hawthorn JA,Neale MH,Terry LA

更新日期：2010-09-15 00:00:00

abstract：:H7N9 influenza A first caused human infections in early 2013 in China. Virus genetics, histories of patient exposures to poultry, and previous experimental studies suggest the source of the virus is a domestic avian species, such as chickens. In order to better understand the ecology of this H7N9 in chickens, we evalu...

journal_title：Virology

authors： Spackman E,Pantin-Jackwood M,Swayne DE,Suarez DL,Kapczynski DR

更新日期：2015-03-01 00:00:00

abstract：:Human Cytomegalovirus (HCMV) is an opportunistic pathogen that causes substantial disease in neonates and immunocompromised individuals. Reverse genetic analysis of the HCMV genome is a powerful tool to dissect the roles that various viral genes play during infection. However, genetic engineering of HCMV is hampered b...

journal_title：Virology

authors： King MW,Munger J

更新日期：2019-03-01 00:00:00

abstract：:We test the hypothesis that the translation machinery in cells infected by influenza A virus efficiently translates only mRNAs that possess the influenza viral 5' untranslated region (5'-UTR) by introducing mRNAs directly into the cytoplasm of infected cells. This strategy avoids effects due to the inhibition of the n...

journal_title：Virology

authors： Cassetti MC,Noah DL,Montelione GT,Krug RM

更新日期：2001-10-25 00:00:00

abstract：:Highly pathogenic alphaviruses display complex glycans on their surface. These glycans play a crucial role in viral pathogenesis by facilitating glycan-host interaction during viral entry which can be targeted. Various studies have reported antiviral activity of lectins that bind to the glycans present on the surface ...

journal_title：Virology

authors： Kaur R,Neetu,Mudgal R,Jose J,Kumar P,Tomar S

更新日期：2019-01-02 00:00:00

abstract：:Specific binding sites for Epstein-Barr virus (EBV) nuclear antigen (EBNA-1), isolated and semipurified from EBV-transformed nonproductive Raji cells, were visualized on the molecule of EBV DNA by electron microscopy and mapped. Two measures had to be applied to counteract the limited purity of the EBNA-1 preparation:...

journal_title：Virology

authors： Reischig J,Bartsch D,Polack A,Vonka V,Hirsch I

更新日期：1987-10-01 00:00:00

abstract：:The OC43 strain of human coronavirus (HCoV-OC43) is an ubiquitous respiratory tract pathogen possessing neurotropic capacities. Coronavirus structural envelope (E) protein possesses specific motifs involved in protein-protein interaction or in homo-oligomeric ion channel formation, which are known to play various role...

journal_title：Virology

authors： Stodola JK,Dubois G,Le Coupanec A,Desforges M,Talbot PJ

更新日期：2018-02-01 00:00:00

abstract：:When electrophoresed in 0.7% agarose gels, populations of reovirus particles can be resolved into 13 well-defined bands that possess from 0 to 12 projection/spike-associated trimers of protein sigma 1. This state of affairs is not an artifact of purification, of the techniques used to demonstrate it, of aggregation, o...

journal_title：Virology

authors： Larson SM,Antczak JB,Joklik WK

更新日期：1994-06-01 00:00:00

abstract：:The reactivates of human sera with uninduced and phorbol ester (TPA)-induced human herpesvirus-8 (HHV-8)-infected BCBL-1 cells were examined by immunofluorescence assay (IFA) and by radioimmunoprecipitation reactions (RIP). The seroprevalence of HHV-8 infections is low in the United States general population and only ...

journal_title：Virology

authors： Chandran B,Smith MS,Koelle DM,Corey L,Horvat R,Goldstein E

更新日期：1998-03-30 00:00:00

abstract：:Beet necrotic yellow vein virus (BNYVV) has a quadripartite plus-strand RNA genome in which the two smallest genome components, RNA 3 and 4, are not necessary for virus multiplication in leaves. Infectious transcripts of BNYVV RNA 3 and 4 have already been described (V. Ziegler-Graff, S. Bouzoubaa, I. Jupin, H. Guille...

journal_title：Virology

authors： Quillet L,Guilley H,Jonard G,Richards K

更新日期：1989-09-01 00:00:00

abstract：:The nonstructural rotavirus receptor glycoprotein NS28 is 175 amino acids long and oriented in the RER membrane with the NH2 terminus on the luminal side and approximately 131 amino acids accessible from the cytoplasmic side. Au et al. (1988) have demonstrated that NS28 is able to interact with rotavirus single-shelle...

journal_title：Virology

authors： Meyer JC,Bergmann CC,Bellamy AR

更新日期：1989-07-01 00:00:00

abstract：:Five revertants of a linker-scanning mutation adjacent to the stem-loop V attenuation determinant (X472) in the 5' noncoding region of poliovirus RNA were independently isolated from neuroblastoma cells and contained RNAs with seven nucleotide changes in the pyrimidine-rich region. Generation of the identical rare sec...

journal_title：Virology

authors： Stewart SR,Semler BL

更新日期：1999-11-25 00:00:00

abstract：:Infection of microglial cells by the human immunodeficiency virus (HIV) is supposed to play an important role in the pathogenesis of AIDS-related central nervous system (CNS) complications. So far, however, experimental data about interactions between HIV and ramified microglia from the adult CNS were only occasionall...

journal_title：Virology

authors： Hein A,Martin JP,Koehren F,Bingen A,Dörries R

更新日期：2000-03-15 00:00:00

abstract：:To better understand the origin of human T-cell leukemia virus type l (HTLV-l) in South America, we conducted a phylogenetic study on 27 new HTLV-ls in Brazil. These were obtained from Brazilians of various ethnic origins, such as Japanese immigrants, whites, blacks and mulattos. We amplified and sequenced proviral DN...

journal_title：Virology

authors： Yamashita M,Veronesi R,Menna-Barreto M,Harrington WJ Jr,Sampio C,Brites C,Badaro R,Andrade-Filho AS,Okhura S,Igarashi T,Takehisa J,Miura T,Chamone D,Bianchini O,Jardim C,Sonoda S,Hayami M

更新日期：1999-08-15 00:00:00

abstract：:To determine the role of piscine anti-viral cytotoxic cells, we analyzed the response of channel catfish to Ictalurid herpesvirus 1, commonly designated channel catfish virus (CCV). Peripheral blood leukocytes (PBL) from catfish immunized with MHC-matched, CCV-infected G14D cells (G14D-CCV) showed marked lysis of G14D...

journal_title：Virology

authors： Taylor EB,Chinchar VG,Quiniou SMA,Wilson M,Bengtén E

更新日期：2020-01-15 00:00:00

abstract：:Mouse mammary tumor virus (MMTV) induces breast cancer in mice in the absence of known virally-encoded oncogenes. Tumorigenesis by MMTV is thought to occur primarily through insertional mutagenesis, leading to the activation of cellular proto-oncogenes and outgrowth of selected cells. Here we investigated whether MMTV...

journal_title：Virology

authors： Kincaid RP,Panicker NG,Lozano MM,Sullivan CS,Dudley JP,Mustafa F

更新日期：2018-01-01 00:00:00

abstract：:Coxsackievirus A16 (CAV16) a member of the Enterovirus genus of Picornaviridae, is associated with hand-foot-and-mouth disease, a febrile papulovesicular rash of childhood. We have determined the complete nucleotide sequence of the genome of the prototype strain of CAV16 which consists of 7413 nucleotides plus the pol...

journal_title：Virology

authors： Pöyry T,Hyypiä T,Horsnell C,Kinnunen L,Hovi T,Stanway G

更新日期：1994-08-01 00:00:00

abstract：:High Plains wheat mosaic virus (HPWMoV, genus Emaravirus; family Fimoviridae), transmitted by the wheat curl mite (Aceria tosichella Keifer), harbors a monocistronic octapartite single-stranded negative-sense RNA genome. In this study, putative proteins encoded by HPWMoV genomic RNAs 2-8 were screened for potential RN...

journal_title：Virology

authors： Gupta AK,Hein GL,Graybosch RA,Tatineni S

更新日期：2018-05-01 00:00:00

abstract：:Many virus-encoded RGD-containing proteins have been reported to play important roles in virus attachment and entry. Here we report the identification and functional characterization of a gene encoding an RGD-containing protein (037L) from large yellow croaker iridovirus (LYCIV), a causative agent of epizootics among ...

journal_title：Virology

authors： Ao J,Chen X

更新日期：2006-11-25 00:00:00

abstract：:The polycation DEAE-dextran increased the binding of VSV to BHK cells about fourfold over a wide range of VSV concentrations. The same proportion of bound virions was internalized by the cell in the presence or absence of DEAE-dextran. Viral primary RNA production was increased to the equivalent of a 4- to 4.5-fold in...

journal_title：Virology

authors： Bailey CA,Miller DK,Lenard J

更新日期：1984-02-01 00:00:00

abstract：:The International Human Papillomavirus (HPV) Reference Center supports quality and order in HPV research and diagnostics. Notably, the center assigns HPV type numbers to novel HPV types, maintains a reference clone repository, and issues international proficiency panels for HPV genotyping. The established HPV types, c...

journal_title：Virology

authors： Mühr LSA,Eklund C,Dillner J

更新日期：2018-06-01 00:00:00

abstract：:Human papilllomaviruses (HPVs) are common human pathogens that infect cutaneous or mucosal epithelia in which they cause warts, self-contained benign lesions that commonly regress. The HPV life cycle is intricately tied to the differentiation of the host epithelium it infects. Mucosotropic HPVs are the most common sex...

journal_title：Virology

authors： Johannsen E,Lambert PF

更新日期：2013-10-01 00:00:00

abstract：:Human keratinocytes (HKc) immortalized by human papillomavirus type 16 DNA (HKc/HPV16) progress toward malignancy through growth factor-independent (HKc/GFI) and differentiation-resistant stages (HKc/DR). This progression is associated with a loss of sensitivity to growth inhibition by both all-trans-retinoic acid (RA...

journal_title：Virology

authors： Mi Y,Borger DR,Fernandes PR,Pirisi L,Creek KE

更新日期：2000-05-10 00:00:00

abstract：:CD8 T cells are necessary for controlling tumors induced by mouse polyoma virus (PyV), but the effector mechanism(s) responsible have not been determined. We examined the PyV tumorigenicity in C57BL/6 mice mutated in Fas or carrying targeted disruptions in the perforin gene or in both TNF receptor type I and type II g...

journal_title：Virology

authors： Byers AM,Hadley A,Lukacher AE

更新日期：2007-02-20 00:00:00

abstract：:Of five globally important VP7 (G) serotypes (G1-4 and 9) of group A rotaviruses (the single most important etiologic agents of infantile diarrhea worldwide), G9 continues to attract considerable attention because of its unique natural history. Serotype G9 rotavirus was isolated from a child with diarrhea first in the...

journal_title：Virology

authors： Hoshino Y,Honma S,Jones RW,Ross J,Santos N,Gentsch JR,Kapikian AZ,Hesse RA

更新日期：2005-02-05 00:00:00

abstract：:The spike (S) and hemagglutinin/esterase (HE) of bovine coronavirus (BCV) are the two envelope proteins that recognize the same receptor-determinant of 9-O-acetylneuraminic acid on host cells. However, the precise and relative roles of the two proteins in BCV infectivity remain elusive. To unequivocally determine thei...

journal_title：Virology

authors： Popova R,Zhang X

更新日期：2002-03-01 00:00:00

abstract：:Poliovirus readily establishes a persistent infection in the K562-Mu erythroleukemia cell strain. In this study, three additional K562 cell strains were analyzed for their responses to poliovirus infection and found to be quite variable. K562 cells obtained from the ATCC established a persistent infection, similar to ...

journal_title：Virology

authors： Benton PA,Murphy JW,Lloyd RE

更新日期：1995-10-20 00:00:00

abstract：:Human cytomegalovirus (HCMV) infects the chorioamnion, but whether these infections cause fetal membrane dysfunction remains poorly understood. We sought to assess whether guinea pig cytomegalovirus (GPCMV) infects amnion-derived cells in vitro, compare the inflammatory response of amnion cells to GPCMV and HCMV, and ...

journal_title：Virology

authors： Putri DS,Berkebile ZW,Mustafa HJ,Fernández-Alarcón C,Abrahante JE,Schleiss MR,Bierle CJ

更新日期：2020-09-01 00:00:00

abstract：:Peste des petits ruminants (PPR) is a viral disease of goats and sheep characterized by erosive stomatitis, enteritis, and pneumonia. The virus is a member of the family Paramyxoviridae and the genus Morbillivirus. The disease has high morbidity and mortality rates and has a substantial economic impact in developing c...

journal_title：Virology

authors： Ismail TM,Yamanaka MK,Saliki JT,el-Kholy A,Mebus C,Yilma T

更新日期：1995-04-20 00:00:00

abstract：:In mid-January 2016, an outbreak of H7N8 high-pathogenicity avian influenza virus (HPAIV) in commercial turkeys occurred in Indiana. Surveillance within the 10km control zone identified H7N8 low-pathogenicity avian influenza virus (LPAIV) in nine surrounding turkey flocks but no other HPAIV-affected premises. We seque...

journal_title：Virology

authors： Lee DH,Torchetti MK,Killian ML,Swayne DE

更新日期：2017-07-01 00:00:00