Abstract：
:Total body bone mineral content (TBBMC), total body bone mineral density (TBBMD), and regional bone mineral content (BMC) were determined with dual energy X-ray absorptiometry and correlated with different anthropometric variables in 324 normal male subjects aged 15 to 85 years, in order to obtain further knowledge of the controversial course of bone mass in males. These subjects showed increased TBBMC and TBBMD up to the age of 25-29 years. A positive and significant (p < 0.001) correlation was observed between TBBMC and TBBMD and with BMC with age (p < 0.001), as well as between age and body weight (p < 0.001) and between the latter and body fat (p < 0.001). Age did not correlate with weight or TBBMC, TBBMD, and regional BMC in subjects older than 29 years, while a significant and positive correlation between body weight and muscle mass was observed with bone mass (p < 0.001). By multiple regression analysis, TBBMC was significantly independent of fat-free mass (FFM) and lean body mass (LBM) (p < 0.01). These findings led us to point out that bone mass increases until the age of 29 years and that changes depend more on weight that on age in men. The rate of bone mass loss with age was 0.23%, that of soft tissue 0.35%, while fat mass increased 0.7% per year.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Rico H,Revilla M,Gonzalez-Riola J,Villa LF,Alvarez de Buergo Mdoi
10.1007/BF02231776subject
Has Abstractpub_date
1993-12-01 00:00:00pages
485-9issue
4eissn
0770-3198issn
1434-9949journal_volume
12pub_type
杂志文章abstract：:The prostaglandin series of bioactive compounds is formed by the interaction of two distinct but related enzymes, cyclo-oxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is a constitutive form which is present mainly in the gastric mucosa, kidney and platelets. COX-2 is mainly an inducible form, although also to...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s100670070024
更新日期：2000-01-01 00:00:00
abstract：:The aim of this study was to ascertain whether fibromyalgia patients with positive ANA develop other features of connective tissue disease over 2-4 years' follow-up. Patients attending our clinic with a diagnosis of fibromyalgia were identified. All ANA-positive patients (n = 12) were recruited and matched for age and...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670200118
更新日期：2002-11-01 00:00:00
abstract：:An insufficiency fracture (IF) involving the acetabulum is presented. This fracture occurred in a 67-year-old woman who had been hysterectomized and oophorectomized 27 years earlier for a carcinoma of the uterine cervix, and who had received external pelvic irradiation. This IF location has been rarely described earli...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207215
更新日期：1992-09-01 00:00:00
abstract：:Chronic hepatitis C virus (HCV) viremia has been known to provoke a plethora of autoimmune syndromes referred to as extrahepatic manifestations of chronic HCV infection. Aim of the current study was to assess the prevalence of rheumatologic manifestations among Egyptians with hepatitis C infection and its' association...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1463-x
更新日期：2010-12-01 00:00:00
abstract：:Simultaneous occurrence of subacute cutaneous lupus erythematosus and malignancy has rarely been reported. We report the first case of subacute cutaneous lupus erythematosus associated with Hodgkin's disease. Although our case does not fulfill the criteria of paraneoplastic process, a relationship between the two diso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207938
更新日期：1995-11-01 00:00:00
abstract：:The effect of niflumic acid on hyaluronic acid and proteoglycan metabolism of human cartilage cells was investigated in vitro. Cartilage cells were obtained from five different donors. Niflumic acid levels used in the test systems ranged from 0 to 22 microgramsr/ml and were comparable to serum concentrations in humans...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02030238
更新日期：1990-03-01 00:00:00
abstract：:The objective of the study was to determine clinical factors associated with activity limitation and predictors of a change in activity limitation after 1 year in people with gout. Two hundred ninety-five participants with gout (disease duration < 10 years) attended a baseline assessment which included medical and dis...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4110-6
更新日期：2018-08-01 00:00:00
abstract：:The population of North Dakota is predominantly of Scandinavian (Norwegian) or German descent. We analyzed a cohort of all patients diagnosed with palindromic rheumatism (PR) and followed-up (by the investigator PK) at the St. Alexius Medical Center, Specialty Clinics, Bismarck, North Dakota, from August 16, 2006 to S...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-009-1280-2
更新日期：2010-01-01 00:00:00
abstract：:A 78-year-old Japanese woman with Sjögren's syndrome complicating immune-mediated aplastic anaemia is described. A diagnosis of aplastic anaemia was made from severe pancytopenia with hypoplastic marrow. Laboratory studies suggested an association of bone marrow suppressive T-lymphocytes with the pathogenesis of aplas...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02231538
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:Antineutrophil cytoplasmic antibodies (ANCAs) are considered a risk factor for granulomatosis with polyangiitis (GPA) exacerbation, especially when staphylococcal superantigens (SAgs) are present in nasal swabs. Their role in monitoring disease activity remains controversial. This study determined the relatio...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04693-0
更新日期：2019-11-01 00:00:00
abstract：:Delayed diagnosis in patients with Churg-Strauss syndrome (CSS) is largely attributed to the variable and nonspecific presentation of the disease's initial symptoms. The aim of the study was to evaluate the effect of delayed diagnosis on the course of CSS. We conducted a retrospective study of 30 CSS patients followed...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-2127-9
更新日期：2013-03-01 00:00:00
abstract：:This study aimed to compare the diagnostic value of ultrasonography to conventional radiography in detecting osteophytes and erosions in the midfoot joints in patients suffering from inflammatory and non-inflammatory joint disease. Patients with current foot radiographs were included and stratified in two cohorts: inf...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3658-x
更新日期：2017-09-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...
journal_title：Clinical rheumatology
pub_type： 信件
doi：10.1007/s10067-004-0922-7
更新日期：2004-12-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the production of autoantibodies and the involvement of multiple organ systems. Systemic sclerosis (SSc) is another autoimmune disease that causes fibrosis. We will aim to analyse the role of killer cell immunoglobulin-like receptor (KIR) gen...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-016-3222-0
更新日期：2016-04-01 00:00:00
abstract：:To date, there have been very few studies on the age dependence of maximal isometric muscle strength (MIMS) in healthy subjects aged 20-80 years, based upon measurements of a large number of functional muscle groups (FMGs). Using a hand-held pull gauge it is possible to measure MIMS of nearly every FMG. The objectives...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670050026
更新日期：2000-01-01 00:00:00
abstract：:The aim of this study was to investigate the association of two common interleukin 12B (IL-12B) polymorphisms (rs3212227 and rs6887695) with rheumatoid arthritis (RA) susceptibility through meta-analyses. A systematic literature search of PubMed, Web of Science, Cochrane Library, and Embase databases was conducted on ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-016-3327-5
更新日期：2017-02-01 00:00:00
abstract：:In the past decade, lung ultrasound (LUS) B-lines and serum Krebs von den Lungen-6 (KL-6) antigen have been recognized as biomarkers of the connective tissue disease-associated interstitial lung diseases (CTD-ILDs). Robust data have demonstrated that B-lines total numbers and KL-6 levels are correlated with high-resol...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04462-z
更新日期：2019-05-01 00:00:00
abstract：:Upper lobe fibrobullous disease is a well-known finding in advanced stages of ankylosing spondylitis (AS). In this report, we present a 57-year-old male patient who was diagnosed with a right apical cavitary lesion after coming to us with the complaint of haemoptysis. The patient underwent upper lobe segmentectomy and...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-004-1047-8
更新日期：2005-08-01 00:00:00
abstract：:Statin-induced necrotising autoimmune myopathy (NAM) is a rare but disabling complication of statin therapy. Data regarding treatment and outcomes in these patients is sparse. We retrospectively identified those patients with a diagnosis of statin-induced NAM who were managed in a single-tertiary referral centre from ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3831-2
更新日期：2018-02-01 00:00:00
abstract：:We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine sampl...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0632-z
更新日期：2007-12-01 00:00:00
abstract：:Fragile X mental retardation 1 (FMR1) premutation carriers, who are at risk of having children with fragile X Syndrome, were initially considered as clinically unaffected. However, recent clinical and molecular studies have shifted this point of view. The incidence of premutation in the general population is substanti...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-2052-y
更新日期：2012-11-01 00:00:00
abstract：:To compare the efficacy and safety of aceclofenac (AC) and tenoxicam (TX) in the treatment of rheumatoid arthritis (RA), a multicentric parallel, randomized, double-blind trial of three months duration was performed in 292 patients: 145 were randomized to the AC treatment group and 147 to the TX treatment group. The t...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/BF02229644
更新日期：1996-09-01 00:00:00
abstract：:Anti-tumour necrosis factor alpha therapy has led to significant advancement in the treatment of rheumatological disease. Rarely, anti-TNFalpha antagonists have been associated with vasculitis, predominantly cutaneous leukocytoclastic vasculitis. We present the first case of angiographically-confirmed digital vasculit...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-008-1015-9
更新日期：2008-12-01 00:00:00
abstract：:The acute renal side-effects of nonsteroidal anti-inflammatory drugs are well documented. These include interstitial nephritis, hyperkalaemia, renal tubular acidosis, fluid retention, hypertension and nephrotic syndrome. The long-term effects are less well known. We have carried out a cross-sectional survey of an unse...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02204466
更新日期：1988-06-01 00:00:00
abstract：:We investigated the all-inclusive echocardiographic features in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) within 3 months before and after diagnosis. We reviewed the medical records of 89 AAV patients taking echocardiography and 35 age- and gender-matched controls. We collect...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3868-2
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:To investigate the clinical characteristics, laboratory features, and treatment outcomes of Thai patients compared between those with necrotizing autoimmune myopathy (NAM) and those with other idiopathic inflammatory myopathies (IIMs) or non-NAM. METHODS:This multicenter case-control study included patients ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10067-019-04756-2
更新日期：2019-12-01 00:00:00
abstract：:We describe the case of a 26-year-old African female who was treated successfully with belimumab in a case of severe membranous lupus nephritis and retinal vasculitis, resistant to first line therapy. She presented initially with chronic dacryoadenitis and screening showed nephrotic-range proteinuria. Biopsy of the ki...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-015-3153-1
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:Gout is a common inflammatory disease, and the prevalence of gout in men is significantly higher than in women. Catechol-O-methyltransferase (COMT) regulates dopamine activity and metabolism, thereby participating in the uric acid metabolism, which in turn affects the occurrence of gout. Our study aimed to in...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04607-0
更新日期：2019-10-01 00:00:00
abstract：:Antibodies to 65Kd heat-shock protein (hsp) of mycobacterium leprae were measured by enzyme-linked immunosorbent assay (ELISA) in the three immunoglobulin classes in paired sera and synovial fluids of patients with rheumatoid arthritis (RA). Titers of anti-hsp antibody were expressed by optical density (OD) values for...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02249023
更新日期：1994-06-01 00:00:00
abstract：:Rituximab is a human/murine chimeric anti-CD20 monoclonal antibody. It is largely used to treat B cell malignancies and has become standard in the management of B cell‑mediated diseases such as rheumatoid arthritis and granulomatosis with polyangitis. The effects of rituximab need to be monitored by B cell phenotyping...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-020-04996-7
更新日期：2020-05-01 00:00:00
