Abstract:
:Phage PR4 contains a lipid bilayer within the phage protein capsid. The phospholipids of the bilayer are derived from those of the host. We report that phage morphogenesis selects against the unusually bulky phospholipids synthesized by Escherichia coli grown in the presence of various sugar alcohols. These data indicate that assembly of the PR4 lipid bilayer is a selective process rather than the bulk appropriation of host membrane lipids. We also demonstrates that phage PR4 morphogenesis is compatible with the incorporation of several abnormal lipids, monoacylglycerol, diacylglycerol, and phosphatidylinositol into the phage particle.
journal_name
Virologyjournal_title
Virologyauthors
Myung H,Cronan JE Jrdoi
10.1006/viro.1994.1004subject
Has Abstractpub_date
1994-01-01 00:00:00pages
25-30issue
1eissn
0042-6822issn
1096-0341pii
S0042-6822(84)71004-Xjournal_volume
198pub_type
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