Scorpion venom peptides with no disulfide bridges: a review.

abstract：:A method has been developed for the study of somatostatin (SS) binding to dissociated cells from rat cerebral cortex. Binding of [125I] [Tyr11]SS to cells obtained by mechanical dissociation of rat cerebral cortex was dependent on time and temperature, saturable, reversible and highly specific. Under conditions of equ...

journal_title：Peptides

authors： Colas B,Prieto JC,Arilla E

更新日期：1990-11-01 00:00:00

abstract：:We examined the effect of adjuvant arthritis on the content of immunoreactive calcitonin gene-related peptide (iCGRP) in the dorsal root ganglia at L4-L6 levels and the spinal cord at a lumbar level in rats. Arthritis was induced by inoculating adjuvant into both hind-paws twice at a 10 day interval. In the arthritic ...

journal_title：Peptides

authors： Kuraishi Y,Nanayama T,Ohno H,Fujii N,Otaka A,Yajima H,Satoh M

更新日期：1989-03-01 00:00:00

abstract：:Japonicin-1 (FFPIGVFCKIFKTC) and japonicin-2 (FGLPMLSILPKALCILLKRKC), two peptides with differential growth-inhibitory activity against the Gram-negative bacterium, Escherichia coli and the Gram-positive bacterium Staphylococcus aureus, were isolated from an extract of the skin of the Japanese brown frog Rana japonica...

journal_title：Peptides

authors： Isaacson T,Soto A,Iwamuro S,Knoop FC,Conlon JM

更新日期：2002-03-01 00:00:00

abstract：:Studies involving altered energy balance states in rodents have demonstrated that hypothalamic neuropeptide Y (NPY) activity is strongly activated in states of negative energy balance, such as periods of dietary restriction or starvation. However, in cancer cachexia, when there is a significant reduction in body weigh...

journal_title：Peptides

authors： King PJ,Widdowson PS,Doods H,Williams G

更新日期：2000-01-01 00:00:00

abstract：:We have cloned melanocortin receptors (MCRs) from several species of fish. The MC4R and MC5R subtypes arose early in vertebrate evolution and their primary structure is remarkably conserved. Expression and pharmacological characterization of the MCRs in fish has revealed that they bind and respond to melanocortin pept...

journal_title：Peptides

authors： Schiöth HB,Haitina T,Ling MK,Ringholm A,Fredriksson R,Cerdá-Reverter JM,Klovins J

更新日期：2005-10-01 00:00:00

abstract：:The ability of acute exercise to stimulate appetite and food intake depends on intensity, duration, and agouti-related protein (AGRP) levels. Fasting, as well as any negative energy balance, has been reported to increase AGRP expression in the arcuate nucleus (ARC) of the hypothalamus and other extra-hypothalamic tiss...

journal_title：Peptides

authors： Ghanbari-Niaki A,Nabatchian S,Hedayati M

更新日期：2007-05-01 00:00:00

abstract：:Pretreatment with opioid antagonists enhances acquisition of Pavlovian fear conditioning. The present experiments attempted to characterize the type of opioid receptor responsible for this effect using a procedure that assessed the fear of rats to a chamber previously associated with electric shock (1 mA, 0.75 s). Fre...

journal_title：Peptides

authors： Fanselow MS,Kim JJ,Young SL,Calcagnetti DJ,DeCola JP,Helmstetter FJ,Landeira-Fernandez J

更新日期：1991-09-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) and mucins are components of airway secretions and both contribute to the innate host defense system. At neutral pH, AMPs are positively charged, mucins negatively. It was the aim of the study to test whether these opposite charges result in interactions between AMPs and mucins. We measur...

journal_title：Peptides

authors： Felgentreff K,Beisswenger C,Griese M,Gulder T,Bringmann G,Bals R

更新日期：2006-12-01 00:00:00

abstract：:We examined the expressions of the prepro-orexin gene in the lateral hypothalamic area (LHA), the genes of the neuropeptide Y (NPY) and proopiomelanocortin (POMC) in the arcuate nucleus (ARC), the orexin type 1 receptor (OX1R) gene in the ventromedial hypothalamic nucleus (VMH) and the orexin type 2 receptor (OX2R) ge...

journal_title：Peptides

authors： Yamamoto Y,Ueta Y,Yamashita H,Asayama K,Shirahata A

更新日期：2002-09-01 00:00:00

abstract：:Receptor binding analysis was performed in the renal medulla from 2-month-old rats, an extrapituitary tissue containing the highest level of GHRH receptor mRNA. At 4 degrees C, in the presence of a cocktail of protease inhibitors, binding of [125I-Tyr(10)]hGHRH (1-44)NH(2) to medullary homogenates was specific, time-d...

journal_title：Peptides

authors： Boulanger L,Girard N,Strecko J,Gaudreau P

更新日期：2002-06-01 00:00:00

abstract：:Growing evidence suggests that the neuropeptide Y (NPY) system plays an important role in the immune system. Yet, little is known about the expression of NPY and receptors in the immune system. Moreover, original contradicting results have confused the picture and hampered a clear understanding of its role in the immu...

journal_title：Peptides

authors： Wheway J,Herzog H,Mackay F

更新日期：2007-02-01 00:00:00

abstract：:The effect of melanin-concentrating hormone (MCH) on the release of alpha-melanocyte stimulating hormone (alpha-MSH) from the tilapia pituitary gland was studied in vitro. In a superfusion set up, 10 nM to 1 microM synthetic salmon MCH caused a concentration-dependent inhibition of alpha-MSH release from tilapia neuro...

journal_title：Peptides

authors： Gröneveld D,Balm PH,Wendelaar Bonga SE

更新日期：1995-01-01 00:00:00

abstract：:Ethanol (ETOH) has been shown to have pronounced effects on reproductive endocrinology in humans as well as laboratory animals. We have studied the effects of ETOH on the hypothalamic-pituitary-luteinizing hormone (LH) axis, using the male rat as an animal model. In order to better understand the method by which ETOH ...

journal_title：Peptides

authors： Dees WL,Kozlowski GP

更新日期：1984-01-01 00:00:00

abstract：:High levels of neuropeptide Y (NPY) are found in the hypothalamus, median eminence, pituitary portal blood, and the pituitary in a number of species. Neuropeptide Y may influence the synthesis and secretion of a variety of hormones by interacting with specific receptors in the hypothalamus and/or the pituitary. To fur...

journal_title：Peptides

authors： Gehlert DR,Gackenheimer SL,Millington WR,Manning AB,Chronwall BM

更新日期：1994-01-01 00:00:00

abstract：:The chronic hyperglycemia measured alongside diabetes development is associated with significant long-term damage and failure of various organs. In the present study it was shown that hyperglycemia induced early and long term increases in nitric oxide (NO) levels, kallikrein activity and vascular capillary permeabilit...

journal_title：Peptides

authors： Catanzaro O,Labal E,Andornino A,Capponi JA,Di Martino I,Sirois P

更新日期：2012-04-01 00:00:00

abstract：:The effects of iontophoretically applied human pancreatic growth hormone-releasing factor (hpGRF), peptide histidine isoleucine (PHI-27), and somatostatin (SS) on the extracellular activity of single cells in the hypothalamus, thalamus, and cortex of the rat brain were studied in urethane-anesthetized, male rats. Neur...

journal_title：Peptides

authors： Twery MJ,Moss RL

更新日期：1985-07-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP) is a neuropeptide present in high concentrations in the hippocampus. The studies reported here demonstrate that VIP administered into the third ventricle of the brain caused amnesia in mice trained on a left-right footshock avoidance task in a T-maze. VIP resulted in amnesia when ad...

journal_title：Peptides

authors： Flood JF,Garland JS,Morley JE

更新日期：1990-09-01 00:00:00

abstract：:Corticotropin releasing hormone (CRH) stimulates pituitary ACTH secretion through type-1 CRH (CRH1) receptors. Stimulation of the hypothalamic pituitary adrenal (HPA) axis as well as increased corticotroph responsiveness during stress and adrenalectomy are associated with marked pituitary CRH binding downregulation. T...

journal_title：Peptides

authors： Aguilera G,Rabadan-Diehl C,Nikodemova M

更新日期：2001-05-01 00:00:00

abstract：:DDSDEEN chromatin peptide, after dansylation, was studied for its ability to bind N-CAM protein. The binding causes a quenching of the Dns-peptide fluorescence emission. Dose- and time-dependent binding of Dns-peptide with N-CAM has been shown. Fluorescence quenching is completely lost if the Dns-peptide is subjected ...

journal_title：Peptides

authors： Marsili V,Lupidi G,Berellini G,Calzuola I,Perni S,Cruciani G,Gianfranceschi GL

更新日期：2008-12-01 00:00:00

abstract：:A novel antimicrobial peptide named odorranain-NR was identified from skin secretions of the diskless odorous frog, Odorrana grahami. It is composed of 23 amino acids with an amino acid sequence of GLLSGILGAGKHIVCGLTGCAKA. Odorranain-NR was classified into a novel family of antimicrobial peptide although it shared sim...

journal_title：Peptides

authors： Che Q,Zhou Y,Yang H,Li J,Xu X,Lai R

更新日期：2008-04-01 00:00:00

abstract：:Circulating urotensin II (UII) concentrations and the tissue expression of its cognate receptor (UT) are elevated in patients with cardiovascular disease (CVD). The functional significance of elevated plasma UII levels in CVD is unclear. Urotensin-related peptide (URP) is a paralog of UII in that it contains the six a...

journal_title：Peptides

authors： Prosser HC,Forster ME,Richards AM,Pemberton CJ

更新日期：2008-05-01 00:00:00

abstract：:Sympathetic neurotransmitter neuropeptide Y (NPY) is associated with vascular remodelling, neointimal hyperplasia and atherosclerosis in experimental animal models and clinical studies. In order to study the role of sympathetic nerve-produced NPY in vascular diseases, transgenic mouse model overexpressing NPY in centr...

journal_title：Peptides

authors： Ruohonen ST,Abe K,Kero M,Toukola L,Ruohonen S,Röyttä M,Koulu M,Pesonen U,Zukowska Z,Savontaus E

更新日期：2009-04-01 00:00:00

abstract：:Bacillus thuringiensis subsp. israelensis (Bti) produces at least four different crystal proteins that are specifically toxic to different mosquito species and that belong to two non-related family of toxins, Cry and Cyt named Cry4Aa, Cry4Ba, Cry11Aa and Cyt1Aa. Cyt1Aa enhances the activity of Cry4Aa, Cry4Ba or Cry11A...

journal_title：Peptides

authors： Cantón PE,Zanicthe Reyes EZ,Ruiz de Escudero I,Bravo A,Soberón M

更新日期：2011-03-01 00:00:00

abstract：:One novel Kunitz BPTI-like peptide designated as BBPTI-1, with chymotrypsin inhibitory activity was identified from the venom of Burmese Daboia russelii siamensis. It was purified by three steps of chromatography including gel filtration, cation exchange and reversed phase. A partial N-terminal sequence of BBPTI-1, HD...

journal_title：Peptides

authors： Guo CT,McClean S,Shaw C,Rao PF,Ye MY,Bjourson AJ

更新日期：2013-05-01 00:00:00

abstract：:Pinealectomized (PX) and sham animals were administered either AVT (1 ng/kg) or vehicle (1 ml H20). Boxing-kicking-biting episodes were significantly reduced by administration of AVT, F(1,21) = 8.09, p less than 0.009. Crawling under behavior was increased in PXH20 animals (p less than 0.05). Non-aggressive rearing wa...

journal_title：Peptides

authors： Brown R,King MG

更新日期：1984-11-01 00:00:00

abstract：:Two peptides, rHRnG and hproHRnG, which were encoded by the nucleotide sequences complementary to mRNA of rat hypothalamic gonadotropin-releasing hormone (GnRH) and human placental proGnRH(-3-13), respectively, were synthesized. A remarkable hydropathic anti-complementarity was observed in the N-terminal region betwee...

journal_title：Peptides

authors： Görcs TJ,Gottschall PE,Coy DH,Arimura A

更新日期：1986-11-01 00:00:00

abstract：:Echinometra lucunter is an abundant sea urchin found in Brazilian waters. Accidents caused by this animal are common and are characterized by the penetration of the spines in the skin, which raises an inflammatory reaction through mechanical trauma as well as by the presumable action of toxins. Additionally, there hav...

journal_title：Peptides

authors： Sciani JM,Sampaio MC,Zychar BC,Gonçalves LR,Giorgi R,Nogueira Tde O,de Melo RL,Teixeira Cde F,Pimenta DC

更新日期：2014-03-01 00:00:00

abstract：:The identification and characterization of hypothetical membrane proteins from Mycobacterium tuberculosis have led to a better understanding of the mechanisms used by this pathogen to invade and survive inside host cells. This study assessed the presence, transcription, localization and possible biological activity of...

journal_title：Peptides

authors： Cáceres SM,Ocampo M,Arévalo-Pinzón G,Jimenez RA,Patarroyo ME,Patarroyo MA

更新日期：2011-01-01 00:00:00

abstract：:Treatment of cultured rat hepatocytes with cyclosporin A (0.01-1 microM) for 24, 48, or 72 h in the presence of insulin and epidermal growth factor induced an inhibition on cell proliferation in a time- and concentration-dependent manner, with an IC50 = 0.05 microM CsA corresponding to 48-h treatment. The inhibitory e...

journal_title：Peptides

authors： Rodriguez-Henche N,Román ID,Fueyo J,Menor C,Zueco JA,Prieto JC,Guijarro LG

更新日期：1998-01-01 00:00:00

abstract：:Despite its wide distribution in the central nervous system, the presence of Neuropeptide Y (NPY) in peripheral tissues has been detected. White adipose tissue (WAT) is a new site of NPY synthesis and secretion. The development of brown-like adipocytes in WAT is controlled by hypothalamic NPY neurons through interacti...

journal_title：Peptides

authors： Wan Y,Xue R,Wang Y,Zhang Q,Huang S,Wu W,Ye H,Zhang Z,Li Y

更新日期：2015-01-01 00:00:00