Malformation in index pregnancy in women with epilepsy is not followed by recurrence in subsequent pregnancy.

abstract：PURPOSE:We sought to characterize and compare the histopathologic and clinical changes elicited by subdural and depth electrodes in subjects undergoing epilepsy surgery evaluation. METHODS:A retrospective review of clinical records, imaging and histopathologic studies of epilepsy surgery cases requiring subdural strip...

journal_title：Epilepsia

authors： Stephan CL,Kepes JJ,SantaCruz K,Wilkinson SB,Fegley B,Osorio I

更新日期：2001-07-01 00:00:00

abstract：PURPOSE:We analyzed sequential changes in the localization of EEG foci along with age to identify a specific EEG pattern, and the relation between the clinical manifestations and the EEG pattern in patients with Panayiotopoulos syndrome (PS). METHODS:The subjects were 76 children, who had been followed up >2 years wit...

journal_title：Epilepsia

authors： Ohtsu M,Oguni H,Hayashi K,Funatsuka M,Imai K,Osawa M

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:Several experimental paradigms of seizure induction that produce epilepsy as a consequence have been shown to be associated with the proliferation of dentate granule cells. In developing animals, the acute sequela of hilar damage and the chronic sequelae of spontaneous seizures and mossy fiber synaptic reorgani...

journal_title：Epilepsia

authors： Sankar R,Shin D,Liu H,Katsumori H,Wasterlain CG

更新日期：2000-01-01 00:00:00

abstract：:The anticonvulsant and motor effects of gabapentin (GBP) were evaluated in rat pups aged 16-17 days. Fourteen-day-old rat pups received an implanted stimulating electrode in the amygdala unilaterally. Kindled seizures were produced on day 16 of life by repeatedly applying an electrical current stimulus to the amygdala...

journal_title：Epilepsia

authors： Lado FA,Sperber EF,Moshé SL

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:We aimed to compare the efficacy, safety, and tolerability of a modified Atkins diet (MAD) with the classic ketogenic diet (KD) for the treatment of intractable childhood epilepsy. METHODS:From March 2011 to March 2014, 104 patients aged 1-18 years who had refractory epilepsy were randomly assigned to each d...

journal_title：Epilepsia

authors： Kim JA,Yoon JR,Lee EJ,Lee JS,Kim JT,Kim HD,Kang HC

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Ictal single-photon emission computed tomography (SPECT) may help localize the seizure-onset zone (SOZ) by detecting changes in regional cerebral blood flow induced by epileptic discharges. This imaging method also reveals hyperperfusions in areas of seizure propagation, including the hemisphere contralateral t...

journal_title：Epilepsia

authors： Huberfeld G,Habert MO,Clemenceau S,Maksud P,Baulac M,Adam C

更新日期：2006-01-01 00:00:00

abstract：:The interictal EEG provides information that aids in diagnosis and management of epilepsy. One must remember that the EEG is merely a tool, and its usefulness depends largely upon the skill of the individual who wields it. Like all diagnostic tests, it has significant limitations and cannot substitute for a careful hi...

journal_title：Epilepsia

authors： Pillai J,Sperling MR

更新日期：2006-01-01 00:00:00

abstract：:Alterations in the balance of K-Na-2Cl cotransporter (NKCC1) and Na-Cl cotransporter (KCC2) activity may cause depolarizing effect of γ-aminobutyric Acid (GABA), and contribute to epileptogenesis in human temporal lobe epilepsy. NKCC1 facilitates accumulation of chloride inside neurons and favors depolarizing response...

journal_title：Epilepsia

authors： Eftekhari S,Mehvari Habibabadi J,Najafi Ziarani M,Hashemi Fesharaki SS,Gharakhani M,Mostafavi H,Joghataei MT,Beladimoghadam N,Rahimian E,Hadjighassem MR

更新日期：2013-01-01 00:00:00

abstract：:Eslicarbazepine acetate (ESL) is a novel once-daily antiepileptic drug (AED) approved in Europe since 2009 that was found to be efficacious and well tolerated in a phase III clinical program in adult patients with partial onset seizures previously not controlled with treatment with one to three AEDs, including carbama...

journal_title：Epilepsia

authors： Bialer M,Soares-da-Silva P

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Schizophrenia and epilepsy may share a mutual susceptibility. This study examined the bidirectional relation between the two disorders. METHODS:We used claims data obtained from the Taiwan National Health Insurance database to conduct retrospective cohort analyses. Analysis 1 compared 5,195 patients with incid...

journal_title：Epilepsia

authors： Chang YT,Chen PC,Tsai IJ,Sung FC,Chin ZN,Kuo HT,Tsai CH,Chou IC

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To identify features of ablations and trajectories that correlate with optimal seizure control and minimize the risk of neurocognitive deficits in patients undergoing laser interstitial thermal therapy (LiTT) for mesiotemporal epilepsy (mTLE). METHODS:Clinical and radiographic data were reviewed from a prosp...

journal_title：Epilepsia

authors： Jermakowicz WJ,Kanner AM,Sur S,Bermudez C,D'Haese PF,Kolcun JPG,Cajigas I,Li R,Millan C,Ribot R,Serrano EA,Velez N,Lowe MR,Rey GJ,Jagid JR

更新日期：2017-05-01 00:00:00

abstract：:Steady-state plasma antiepileptic drug (AED) concentrations were measured at intervals throughout pregnancy and during the postnatal period in 105 women who underwent 134 pregnancies. Phenytoin (PHT) dosage had to be increased in 85% of pregnancies in which the drug was received, carbamazepine (CBZ) dosage in 70%, and...

journal_title：Epilepsia

authors： Lander CM,Eadie MJ

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:To explore the correlations between treatment modalities and selected disease parameters with outcome in febrile infection-related epilepsy syndrome (FIRES), a catastrophic epileptic encephalopathy with a yet undefined etiology. METHODS:We conducted a retrospective multicenter study on children who had been in...

journal_title：Epilepsia

authors： Kramer U,Chi CS,Lin KL,Specchio N,Sahin M,Olson H,Nabbout R,Kluger G,Lin JJ,van Baalen A

更新日期：2011-11-01 00:00:00

abstract：:Identical twins concordant for partial epilepsy, with onset at 8 and 11 years of age, are presented. Their course has been benign on anticonvulsant therapy. It is suggested that these cases of presumed genetic epilepsy support current concepts of cortical origin and genetic determinants in several subtypes of focal ep...

journal_title：Epilepsia

authors： Hurst R,Lenn NJ

更新日期：1986-03-01 00:00:00

abstract：:Little is known about what factors predict intractable epilepsy at the time of initial diagnosis. We performed a case-control study to identify early predictors of medically intractable epilepsy in children. Cases were children who had an average of one seizure or more a month over a 2-year period and who, during that...

journal_title：Epilepsia

authors： Berg AT,Levy SR,Novotny EJ,Shinnar S

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:To identify the temporal lobe cortical dysplasia (CD) histopathology classification subtype and determine the seizure outcome of patients who underwent temporal lobectomy with coincident CD. METHODS:We reviewed the data of 28 patients with temporal lobe epilepsy who underwent surgery with pathologically verifi...

journal_title：Epilepsia

authors： Srikijvilaikul T,Najm IM,Hovinga CA,Prayson RA,Gonzalez-Martinez J,Bingaman WE

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:To conduct the first randomized trial on classical and medium-chain triglyceride (MCT) versions of the ketogenic diet, examining efficacy and tolerability after 3, 6, and 12 months. METHODS:One hundred forty-five children with intractable epilepsy were randomized to receive a classical or an MCT diet. Seizure ...

journal_title：Epilepsia

authors： Neal EG,Chaffe H,Schwartz RH,Lawson MS,Edwards N,Fitzsimmons G,Whitney A,Cross JH

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:Structural variations disrupting the gene encoding the neuron-specific splicing regulator RBFOX1 have been reported in three patients exhibiting epilepsy in comorbidity with other neuropsychiatric disorders. Consistently, the Rbfox1 knockout mouse model showed an increased susceptibility of seizures. The presen...

journal_title：Epilepsia

authors： Lal D,Trucks H,Møller RS,Hjalgrim H,Koeleman BP,de Kovel CG,Visscher F,Weber YG,Lerche H,Becker F,Schankin CJ,Neubauer BA,Surges R,Kunz WS,Zimprich F,Franke A,Illig T,Ried JS,Leu C,Nürnberg P,Sander T,EMINet Con

更新日期：2013-02-01 00:00:00

abstract：:The effect od dipropylacetic acid (DPA; Depakine) on the bemegride-induced convulsive threshold was investigated in alert cats. Forty-five min after DPA 200 mg/kg, s.c., no significant effect was obtained; 5 min after the same dose iv., protection from bemegride-induced seizures was pronounced. DPA did not decrease fo...

journal_title：Epilepsia

authors： van Duijn H,Beckmann MK

更新日期：1975-03-01 00:00:00

abstract：PURPOSE:Stereotactic radiofrequency amygdalohippocampectomy (SAHE) has been modified recently in our center for the therapy of mesial temporal epilepsy (MTLE). It has promising clinical results comparable with microsurgical amygdalohippocampectomy despite smaller volume reduction of the hippocampus. We hypothesized tha...

journal_title：Epilepsia

authors： Malikova H,Liscak R,Vojtech Z,Prochazka T,Vymazal J,Vladyka V,Druga R

更新日期：2011-05-01 00:00:00

abstract：:Impaired consciousness in epilepsy has a major negative impact on quality of life. Prior work suggests that complex partial seizures (CPS) and generalized tonic-clonic seizures (GTCS), which both cause loss of consciousness, affect similar frontoparietal networks. Milder involvement in CPS than in GTCS may spare some ...

journal_title：Epilepsia

authors： McPherson A,Rojas L,Bauerschmidt A,Ezeani CC,Yang L,Motelow JE,Farooque P,Detyniecki K,Giacino JT,Blumenfeld H

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:Ictal vomiting represents a rare clinical manifestation during seizures originating from the temporal lobes of the nondominant hemisphere. The precise anatomic structures responsible for generation of ictal vomiting remain to be clarified. Ictal single photon emission computed tomography (SPECT), which allows o...

journal_title：Epilepsia

authors： Baumgartner C,Olbrich A,Lindinger G,Pataraia E,Gröppel G,Bacher J,Aull S,Serles W,Hoffmann M,Leutmezer F,Czech T,Prayer D,Pietrzyk U,Asenbaum S,Podreka I

更新日期：1999-08-01 00:00:00

abstract：:Nonepileptic seizures (NES) are common and are often diagnosed at epilepsy centers by video-EEG recording of both spontaneous and suggestion-induced episodes, but no study has evaluated provocative testing in a general seizure population. We studied consecutive patients with a tentative diagnosis of epilepsy using sal...

journal_title：Epilepsia

authors： Bazil CW,Kothari M,Luciano D,Moroney J,Song S,Vasquez B,Weinreb HJ,Devinsky O

更新日期：1994-07-01 00:00:00

abstract：:The literature dealing with the convulsant effects of the antidepressant drugs of the non-monoamine oxidase inhibitor variety is reviews. It is concluded that most of these drugs do lower the seizure threshold and may precipitate seizures even at normal therapeutic doses. The pathophysiology of antidepressant-induced ...

journal_title：Epilepsia

authors： Trimble M

更新日期：1978-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to systematically review the literature on the interictal language profile in adult patients with epilepsy. METHODS:An extensive literature search was performed using MEDLINE, Embase, PsycINFO, Cochrane Central Register of Controlled Trials, PASCAL, and PSYNDEXplus databases. Ke...

journal_title：Epilepsia

authors： Bartha-Doering L,Trinka E

更新日期：2014-10-01 00:00:00

abstract：:Children with epilepsy often grow into adults with significant social problems including decreased employment, marriage, social relationships, and independent living arrangements. These problems are noted in population-based longitudinal and cross-sectional studies from many countries. Learning disorder and mental han...

journal_title：Epilepsia

authors： Camfield CS,Camfield PR

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Hyperventilation is an activation method that provokes physiological slowing of brain rhythms, interictal discharges, and seizures, especially in generalized idiopathic epilepsies. In this study we assessed its effectiveness in inducing focal seizures during video-EEG monitoring. METHODS:We analyzed the effect...

journal_title：Epilepsia

authors： Guaranha MS,Garzon E,Buchpiguel CA,Tazima S,Yacubian EM,Sakamoto AC

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (MRg-LITT) is an alternative to open epilepsy surgery. We assess safety and effectiveness of MRg-LITT for extratemporal lobe epilepsy (ETLE) in patients who are considered less favorable for open resection. METHODS:We retrospectively ...

journal_title：Epilepsia

authors： Gupta K,Cabaniss B,Kheder A,Gedela S,Koch P,Hewitt KC,Alwaki A,Rich C,Ramesha S,Hu R,Drane DL,Gross RE,Willie JT

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To describe the correlation between visual field loss and the duration, dosage, and total amount of vigabatrin (VGB) medication in a group of patients with epilepsy. Co-medication of antiepileptic drugs (AEDs) and compliance were also studied. METHODS:Ninety-two patients (53 male and 39 female) taking VGB medi...

journal_title：Epilepsia

authors： Hardus P,Verduin WM,Engelsman M,Edelbroek PM,Segers JP,Berendschot TT,Stilma JS

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:Self-management challenges facing adults with epilepsy include limited understanding of the condition and treatment, associated psychosocial issues, and lack of community integration. Self-management interventions improve patients' medical, life role, and emotional management. Previous interventions, develope...

journal_title：Epilepsia

authors： Fraser RT,Johnson EK,Lashley S,Barber J,Chaytor N,Miller JW,Ciechanowski P,Temkin N,Caylor L

更新日期：2015-08-01 00:00:00