Seizure outcome after temporal lobectomy in temporal lobe cortical dysplasia.

abstract：:Little is known about the effects of carbamazepine (CBZ) on sleep despite the relationship between sleep and epilepsy and the common clinical use of CBZ. As part of a larger study on sleep and interictal activity in kindled cats, we performed sleep recordings in 11 normal cats before and after acute administration of ...

journal_title：Epilepsia

authors： Gigli GL,Gotman J,Thomas ST

更新日期：1988-11-01 00:00:00

abstract：:The fragile X mental retardation 1 gene (Fmr1) is polymorphic for CGG trinucleotide repeat number in the 5'-untranslated region, with repeat lengths <45 associated with typical development and repeat lengths >200 resulting in hypermethylation and transcriptional silencing of the gene and mental retardation in the frag...

journal_title：Epilepsia

authors： Berman RF,Murray KD,Arque G,Hunsaker MR,Wenzel HJ

更新日期：2012-06-01 00:00:00

abstract：:Two patients developed clinical and laboratory evidence of systemic lupus erythematosus (SLE) during treatment with valproate (VPA) preparations. The first patient, a 47-year-old man, had fever, malaise, and thrombocytopenia 1 month after VPA was added to phenytoin (PHT) and primidone (PRM). He developed high titers o...

journal_title：Epilepsia

authors： Bleck TP,Smith MC

更新日期：1990-05-01 00:00:00

abstract：:Established antiepileptic drugs (AEDs) decrease membrane excitability by interacting with neurotransmitter receptors or ion channels. AEDs developed before 1980 appear to act on sodium channels, gamma-aminobutyric acid type A (GABAA) receptors, or calcium channels. Benzodiazepines and barbiturates enhance GABAA recept...

journal_title：Epilepsia

authors： Macdonald RL,Kelly KM

更新日期：1995-01-01 00:00:00

abstract：:This article reviews the potential interactions of antiepileptic drugs (AEDs) and the pharmacokinetic and pharmacodynamic principles involved. It describes the absorptive and distributive properties of AEDs and the effects on protein binding, hepatic metabolism, and elimination resulting from co-administration of AEDs...

journal_title：Epilepsia

authors： French JA,Gidal BE

更新日期：2000-01-01 00:00:00

abstract：:Seventy-eight patients with temporal lobe type seizures were precisely matched for age, sex, and Wechsler I.Q. levels with patients suffering from other seizure types. Statistically significant differences were established between the groups in regard to treatment response, etiologies, and behavioral variables. Furthe...

journal_title：Epilepsia

authors： Rodin EA,Katz M,Lennox K

更新日期：1976-09-01 00:00:00

abstract：:To improve the diagnostic accuracy of electroencephalography (EEG) criteria for nonconvulsive status epilepticus (NCSE), external validation of the recently proposed Salzburg criteria is paramount. We performed an external, retrospective, diagnostic accuracy study of the Salzburg criteria, using EEG recordings from pa...

journal_title：Epilepsia

authors： Goselink RJM,van Dillen JJ,Aerts M,Arends J,van Asch C,van der Linden I,Pasman J,Saris CGJ,Zwarts M,van Alfen N

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:The role of the superior colliculus (SC) in seizure expression is controversial and appears to be dependent upon the epilepsy model. This study shows the effect of disconnection between SC deep layers and adjacent tissues in the expression of acute and kindling seizures. METHODS:Subcollicular transections, abl...

journal_title：Epilepsia

authors： Doretto MC,Cortes-de-Oliveira JA,Rossetti F,Garcia-Cairasco N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:Benign partial epilepsy (BPE) in childhood is characterized by the occurrence of interictal stereotyped focal spikes with variable localization in the EEG. Children with BPE often exhibit neuropsychological deficits. It is unclear whether a correlation exists between these deficits and the localization of spike...

journal_title：Epilepsia

authors： Wolff M,Weiskopf N,Serra E,Preissl H,Birbaumer N,Kraegeloh-Mann I

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of new onset epilepsy and associated risk factors in patients with periodic patterns on continuous electroencephalography (cEEG) during critical illness. METHODS:The local cEEG database and then medical records were reviewed from January 1, 2013 to June 30, 2013 to find adult patien...

journal_title：Epilepsia

authors： Punia V,Bena J,Krishnan B,Newey C,Hantus S

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:The aim of this prospective incident community-based study was to assess the influence of pre- and perinatal risk factors in children in whom an unprovoked afebrile epileptic seizure later developed. METHODS:From November 1, 1985, until June 30, 1987, 75 children aged 0-15 years with a first unprovoked afebril...

journal_title：Epilepsia

authors： Sidenvall R,Heijbel J,Blomquist HK,Nyström L,Forsgren L

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:Temporal lobe epilepsy is associated with the inflammatory process related to the basic mechanisms that lead to seizure susceptibility and brain damage. Platelet-activating factor (PAF), a potent, short-lived phospholipid mediator of inflammation, participates in physiologic signaling in the brain. However, aft...

journal_title：Epilepsia

authors： Musto AE,Samii M

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Brivaracetam (BRV), a selective and high-affinity synaptic vesicle protein 2A ligand, is in development as adjunctive treatment for partial-onset (focal) seizures (POS). This phase 3 study (N01358; NCT01261325) aimed to confirm the efficacy and safety/tolerability of BRV in adults (≥ 16-80 years) with POS. M...

journal_title：Epilepsia

authors： Klein P,Schiemann J,Sperling MR,Whitesides J,Liang W,Stalvey T,Brandt C,Kwan P

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:  Preclinical data have suggested that selective serotonin reuptake inhibitors (SSRIs) may have anticonvulsant properties, and some SSRIs are known to modulate ion channels in vitro. We screened citalopram, fluoxetine, and sertraline for anticonvulsant actions in mouse hippocampal slices, and studied the effect...

journal_title：Epilepsia

authors： Igelström KM,Heyward PM

更新日期：2012-11-01 00:00:00

abstract：:[3H]Nimodipine and high-affinity [125I]omega-conotoxin GVIA (CgTX) binding were investigated in membranes from rat cerebral cortex, cerebellum, and hippocampus after electrically and chemically induced seizures. Animals were decapitated 30 min after a single electroconvulsive shock (ECS) or lidocaine-induced seizure a...

journal_title：Epilepsia

authors： Gleiter CH,Cain CJ,Weiss SR,Post RM,Marangos PJ

更新日期：1989-07-01 00:00:00

abstract：:The purpose of the study was to examine the impact of idiopathic epilepsy on mothers and fathers in terms of strain, burden of care, worries and perception of vulnerability. Data were collected and analyzed shortly after the diagnosis (T0) and 12 months later (T1). The results indicated that at T0 parents of children ...

journal_title：Epilepsia

authors： Ramaglia G,Romeo A,Viri M,Lodi M,Sacchi S,Cioffi G

更新日期：2007-09-01 00:00:00

abstract：:The ketogenic diet (KD) is a medical nutrition therapy (MNT) for the treatment of epilepsy. As such, it can affect the outcome of an individual's health and chronic medical condition. The components of MNT which have been established by the American Dietetic Association as core guidelines for nutrition care include a ...

journal_title：Epilepsia

authors： Zupec-Kania B,Zupanc ML

更新日期：2008-11-01 00:00:00

abstract：:A case-control study of 305 children was done to evaluate the relationship between toxocariasis and seizures and risk factors associated with toxocariasis transmission and seizure onset. A significant association existed between seropositivity for anti-Toxocara canis and seizures (p less than 0.05); the correlation wa...

journal_title：Epilepsia

authors： Arpino C,Gattinara GC,Piergili D,Curatolo P

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To investigate further the membrane properties and postsynaptic potentials of the CA3 pyramidal cells in mice that display spontaneous seizures because of a targeted deletion of the Kcna1 potassium channel gene (encoding the Kv1.1 protein subunit). METHODS:Intracellular recordings were obtained from CA3 pyrami...

journal_title：Epilepsia

authors： Lopantsev V,Tempel BL,Schwartzkroin PA

更新日期：2003-12-01 00:00:00

abstract：:Sleep and epilepsy are interrelated. Understanding the relationship between epilepsy and sleep is important for optimizing management of the epilepsy patient in several ways. First, sleep modulates the expression of epileptic seizures and interictal epileptiform discharges. Second, epilepsy and its treatment influence...

journal_title：Epilepsia

authors： Malow BA

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Electroencephalographic seizures (ESs) are common in encephalopathic critically ill children, but identification requires extensive resources for continuous electroencephalographic monitoring (CEEG). In a previous study, we developed a clinical prediction rule using three clinical variables (age, acute enceph...

journal_title：Epilepsia

authors： Fung FW,Parikh DS,Jacobwitz M,Vala L,Donnelly M,Wang Z,Xiao R,Topjian AA,Abend NS

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:To describe the behavioral and EEG topographic correlates of absences with 3-Hz generalized spike-waves and partitioned impairment of consciousness. METHODS:Two adult women had so-called "phantom" absences, characterized by brief and mild impairments of consciousness that were previously inconspicuous to both ...

journal_title：Epilepsia

authors： Vuilleumier P,Assal F,Blanke O,Jallon P

更新日期：2000-06-01 00:00:00

abstract：PURPOSE:Previous studies have documented a synaptic translocation of calcineurin (CaN) and increased CaN activity following status epilepticus (SE); however, the cellular effect of these changes in CaN in the pathology of SE remains to be elucidated. This study examined a CaN-dependent modification of the dendritic cyt...

journal_title：Epilepsia

authors： Kurz JE,Moore BJ,Henderson SC,Campbell JN,Churn SB

更新日期：2008-10-01 00:00:00

abstract：:A need for prevalence information emphasizing racial differences prompted a door-to-door survey of all residents of Copiah County, Mississippi. The fieldwork involved a complete census and an extensive screening questionnaire inquiring about diagnoses, signs, and symptoms of neurologic disease. Residents who lived in ...

journal_title：Epilepsia

authors： Haerer AF,Anderson DW,Schoenberg BS

更新日期：1986-01-01 00:00:00

abstract：:Temporal lobe epilepsy patients (n = 48) and healthy controls (n = 69) underwent structured psychiatric interview at baseline and 4 years later to characterize the course of DSM-IV Axis I disorders. Adjusting for the influence of prior psychiatric history, epilepsy subjects exhibit significantly greater risk of interv...

journal_title：Epilepsia

authors： Jones JE,Bell B,Fine J,Rutecki P,Seidenberg M,Hermann B

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:Originally derived from a Wistar rat strain, a proportion of which displayed spontaneous absence-type seizures, Genetic Absence Epilepsy Rats from Strasbourg (GAERS) represent the most widely utilized animal model of genetic generalized epilepsy. Here we compare the seizure, behavioral, and brain morphometric...

journal_title：Epilepsia

authors： Powell KL,Tang H,Ng C,Guillemain I,Dieuset G,Dezsi G,Çarçak N,Onat F,Martin B,O'Brien TJ,Depaulis A,Jones NC

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:We studied the efficacy and safety of bilateral subthalamic deep brain stimulation (DBS) for refractory partial-onset epilepsy in two cases. METHODS:This was an open treatment pilot study for subjects who had failed numerous medications and had seizure injuries. Seizure counts and adverse events were collected...

journal_title：Epilepsia

authors： Handforth A,DeSalles AA,Krahl SE

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:To evaluate the pharmacokinetics and safety of multiple oral doses of tiagabine HCl in subjects with different degrees of hepatic impairment. METHODS:Four subjects with mild hepatic impairment, three subjects with moderate hepatic impairment, and six matched normal subjects received twice daily oral tiagabine ...

journal_title：Epilepsia

authors： Lau AH,Gustavson LE,Sperelakis R,Lam NP,El-Shourbagy T,Qian JX,Layden T

更新日期：1997-04-01 00:00:00

abstract：PURPOSE:Medically refractory epilepsy caused by cortical tubers resulting from tuberous sclerosis complex (TSC) often requires surgical intervention. The locations of cortical tubers generally are determined by preoperative magnetic resonance imaging (MRI). In this pilot study, we explored the feasibility of using the ...

journal_title：Epilepsia

authors： Oh S,Stewart T,Miller I,Bhatia S,Ragheb J,Duchowny M,Jayakar P,Lin WC

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:Knowledge, attitudes, and perceptions of epilepsy (KAPE) among the public play a major role in determining the extent to which people with epilepsy can be integrated into their society. KAPE SURVEYS IN ASIA:Surveys conducted among Chinese in China, Taiwan, Malaysia, Singapore, and Hong Kong demonstrated simila...

journal_title：Epilepsia

authors： Lim SH,Pan A

更新日期：2005-01-01 00:00:00