Cytotoxic cycloartanes from Aglaia argentea.

Abstract:

:Aglaia argentea leaves yielded three new cycloartanes: argenteanones A and B, and argenteanol. The first two possess cytotoxic activity against KB cells (IC50 7.5 micrograms ml-1 and 6.5 micrograms ml-1 respectively). Structural elucidation was done by two-dimensional NMR spectroscopy.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Omobuwajo OR,Martin MT,Perromat G,Sevenet T,Awang K,Païs M

doi

10.1016/0031-9422(95)00745-8

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

1325-8

issue

5

eissn

0031-9422

issn

1873-3700

pii

0031942295007458

journal_volume

41

pub_type

杂志文章
  • An extensive study on the chemical diversity of lipophilic extractives from Eucalyptus globulus wood.

    abstract::Three mature Eucalyptus globulus trees with 40 years of age were studied at three height levels (0%, 35%, and 60% of total tree height) and at three radial regions (sapwood, inner and outer heartwood). The composition of lipophilic extracts was evaluated and an extensive list of 202 compounds was reported for the firs...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2020.112520

    authors: Gominho J,Lourenço A,Marques AV,Pereira H

    更新日期:2020-12-01 00:00:00

  • RNAi-mediated down-regulation of ornithine decarboxylase (ODC) impedes wound-stress stimulation of anabasine synthesis in Nicotiana glauca.

    abstract::Unlike most Nicotiana species, leaf tissues of the globally significant weed Nicotiana glauca Grah. (Argentinian tree tobacco) contains anabasine as the main component of its alkaloid pool, with concentrations typically increasing several fold in response to wounding of plants. The Δ(1)-piperidinium ring of anabasine ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.10.016

    authors: DeBoer KD,Dalton HL,Edward FJ,Ryan SM,Hamill JD

    更新日期:2013-02-01 00:00:00

  • Phytotoxic naphthopyranone derivatives from the coprophilous fungus Guanomyces polythrix.

    abstract::Reinvestigation of the fermentation broth and mycelium of the coprophilous fungus Guanomyces polythrix, grown in static conditions, led to the isolation of several phytotoxic compounds, including two new naphthopyranone derivatives, namely (2S, 3R)-5-hydroxy-6,8-dimethoxy-2,3-dimethyl-2,3-dihydro-4H-naphtho[2,3-b]-pyr...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00278-3

    authors: Macías M,Gamboa A,Ulloa M,Toscano RA,Mata R

    更新日期:2001-11-01 00:00:00

  • Functional characterization of two acyltransferases from Populus trichocarpa capable of synthesizing benzyl benzoate and salicyl benzoate, potential intermediates in salicinoid phenolic glycoside biosynthesis.

    abstract::Salicinoids are phenolic glycosides (PGs) characteristic of the Salicaceae and are known defenses against insect herbivory. Common examples are salicin, salicortin, tremuloidin, and tremulacin, which accumulate to high concentrations in the leaves and bark of willows and poplars. Although their biosynthetic pathway is...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.10.018

    authors: Chedgy RJ,Köllner TG,Constabel CP

    更新日期:2015-05-01 00:00:00

  • Phytotoxicity and volatile constituents from leaves of Callicarpa japonica Thunb.

    abstract::The essential oil from the leaves of Callicarpa japonica was analyzed by GC-MS, and 84 compounds were identified. The main constituents of the essential oil were spathulenol (18.1%), germacrene B (13.0%), bicyclogermacrene (11.0%), globulol (3.3%), viridiflorol (2.6%), alpha-guaiene (2.3%), and gamma-elemene (2.0%). T...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00207-8

    authors: Kobaisy M,Tellez MR,Dayan FE,Duke SO

    更新日期:2002-09-01 00:00:00

  • Chrysin and other leaf exudate flavonoids in the genus Pelargonium.

    abstract::In a chemotaxonomic survey of 57 Pelargonium species, leaf exudate flavonoids were detected in 35% of the sample, mostly in trace amounts. However, chrysin and a related C-methylflavanone were identified as major leaf surface constituents of P. crispum, and a mixture of quercetin and kaempferol mono-, and di- and trim...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(97)00514-1

    authors: Williams CA,Harborne JB,Newman M,Greenham J,Eagles J

    更新日期:1997-12-01 00:00:00

  • N-Substituted acridone alkaloids from Toddaliopsis bremekampii (Rutaceae: Toddalioideae) of south-central Africa.

    abstract::Toddaliopsins A-D, four novel 1,2,3-trioxygenated acridone alkaloids, have been isolated from the leaves of Toddaliopsis bremekampii. Toddaliopsins B-D are the first reported acridone alkaloids with substituted N-methyl groups, in the light of which the chemotaxonomic relationship of Toddaliopsis and Vepris is discuss...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.04.036

    authors: Naidoo D,Coombes PH,Mulholland DA,Crouch NR,van den Bergh AJ

    更新日期:2005-07-01 00:00:00

  • Essential oils from New Zealand manuka: triketone and other chemotypes of Leptospermum scoparium.

    abstract::The triketone chemotype of manuka, Leptospermum scoparium (Myrtaceae), is commercially important because of its antimicrobial activity. Oils from 36 individual plants on the East Cape of New Zealand all showed similar high triketone contents (>20% total triketones) with little seasonal variation. Analyses of oils from...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2004.03.019

    authors: Douglas MH,van Klink JW,Smallfield BM,Perry NB,Anderson RE,Johnstone P,Weavers RT

    更新日期:2004-05-01 00:00:00

  • Triterpenoid glycosides and a triterpene from Ilex brevicuspis.

    abstract::Two saponins and a sapogenin were isolated from the leaves of Ilex brevicuspis. Their structures were established by means of spectroscopic methods as brevicuspisaponin 1 (3-O-alpha-L-arabinopyranosyl-20(S)-19 alpha,24-dihydroxyursolic acid), brevicuspisaponin 2 (3-O-alpha-L-arabinopyranosyl-20(S)-19 alpha,23,24-trihy...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(99)00517-8

    authors: Taketa AT,Schmittmann-Schlager T,Guillaume D,Gosmann G,Schenkel EP

    更新日期:2000-04-01 00:00:00

  • Uniconazole, a cytochrome P450 inhibitor, inhibits trans-zeatin biosynthesis in Arabidopsis.

    abstract::Cytokinin (CK) is a plant hormone that plays important regulatory roles in many aspects of plant growth and development. Although functions of CK and its biosynthesis pathway have been studied extensively, there is still no efficient biosynthesis inhibitor, which would be useful for studying CK from a chemical genetic...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.11.023

    authors: Sasaki E,Ogura T,Takei K,Kojima M,Kitahata N,Sakakibara H,Asami T,Shimada Y

    更新日期:2013-03-01 00:00:00

  • Kinetics of glucosylated and non-glucosylated aryltetralin lignans in Linum hairy root cultures.

    abstract::Due to their pronounced cytotoxic activity, a number of aryltetralin lignans (ATLs), such as podophyllotoxin (PTOX), are used as antitumor compounds. The production of such molecules from entire plants or plant cell-tissue-organ cultures is thus of interest to the pharmaceutical industry. Hairy root cultures constitut...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.01.001

    authors: Cong LH,Dauwe R,Lequart M,Vinchon S,Renouard S,Fliniaux O,Colas C,Corbin C,Doussot J,Hano C,Lamblin F,Molinié R,Pilard S,Jullian N,Boitel M,Gontier E,Mesnard F,Laberche JC

    更新日期:2015-07-01 00:00:00

  • Seco diterpenoids from Excoecaria agallocha L.

    abstract::Chemical examination of the ethyl acetate solubles of the CH(3)OH:CH(2)Cl(2) (1:1) extract of the roots of Excoecaria agallocha L. collected from Godavary estuary resulted in the isolation of three more new diterpenoids, agallochins M-O (1-3). The structures of the new diterpenoids were elucidated by a study of their ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00269-8

    authors: Anjaneyulu AS,Rao VL

    更新日期:2003-02-01 00:00:00

  • Plant polyphenols: biologically active compounds or non-selective binders to protein?

    abstract::Twenty phenolic compounds, representatives of proanthocyanidins and gallic acid/hexahydroxyldiphenic acid esters of glucose, have been assessed for their ability to inhibit binding of specific radioligands to 16 receptors. The receptors utilized were alpha 1-, alpha 2- and beta-adrenoceptors, adenosine 1, dopamine 1 a...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(96)00598-5

    authors: Zhu M,Phillipson JD,Greengrass PM,Bowery NE,Cai Y

    更新日期:1997-02-01 00:00:00

  • Triterpenoid saponins from Triplostegia grandiflora.

    abstract::Four new oleanane triterpenoid saponins named triplosides D-G were isolated from the roots of Triplostegia grandiflora. Their structures were elucidated on the basis of chemical degradation and spectral evidence. The saponins investigated were: oleanolic acid 3-O-beta-D-xylopyranosyl(1----4)-beta-D-xylopyranosyl(1----...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(92)80287-o

    authors: Ma WG,Wang DZ,Zeng YL,Yang CR

    更新日期:1992-04-01 00:00:00

  • Solar UV-B radiation modulates chemical defenses against Anticarsia gemmatalis larvae in leaves of field-grown soybean.

    abstract::Although it is well known that solar ultraviolet B (UV-B) radiation enhances plant defenses, there is less knowledge about traits that define insect resistance in field-grown soybean. Here we study the effects of solar UV-B radiation on: a) the induction of phenolic compounds and trypsin proteinase inhibitors (TPI) in...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2017.05.006

    authors: Dillon FM,Chludil HD,Zavala JA

    更新日期:2017-09-01 00:00:00

  • Monoterpenoid accumulation in 1,8-cineole, terpinolene and terpinen-4-ol chemotypes of Melaleuca alternifolia seedlings.

    abstract::Individual leaves of the three most common chemotypes of Melaleuca alternifolia were examined both quantitatively and qualitatively for volatile constituents from the emergence of the first true leaves, through to 6-week-old tenth leaf set material. The 1,8-cineole and terpinolene chemotypes were investigated and comp...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00607-6

    authors: Russell MF,Southwell IA

    更新日期:2003-03-01 00:00:00

  • Chemotaxonomy of the Oleaceae: iridoids as taxonomic markers.

    abstract::The distribution and biosynthesis of iridoid glucosides in the Oleaceae is reviewed and five distinct biosynthetic pathways to iridoids have been identified in the family, deoxyloganic acid apparently being a common intermediate. Likewise, the distributions of caffeoyl phenylethanoid glycosides (CPGs), i.e. verbascosi...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/s0031-9422(02)00102-4

    authors: Jensen SR,Franzyk H,Wallander E

    更新日期:2002-06-01 00:00:00

  • Allosteric substrate inhibition of Arabidopsis NAD-dependent malic enzyme 1 is released by fumarate.

    abstract::Plant mitochondria can use L-malate and fumarate, which accumulate in large levels, as respiratory substrates. In part, this property is due to the presence of NAD-dependent malic enzymes (NAD-ME) with particular biochemical characteristics. Arabidopsis NAD-ME1 exhibits a non-hyperbolic behavior for the substrate L-ma...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.11.009

    authors: Tronconi MA,Wheeler MC,Martinatto A,Zubimendi JP,Andreo CS,Drincovich MF

    更新日期:2015-03-01 00:00:00

  • Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera.

    abstract::Six new and three synthetically known glycosides have been isolated from the leaves of Moringa oleifera, employing a bioassay-directed isolation method on the ethanolic extract. Most of these compounds, bearing thiocarbamate, carbamate or nitrile groups, are fully acetylated glycosides, which are very rare in nature. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(94)00729-d

    authors: Faizi S,Siddiqui BS,Saleem R,Siddiqui S,Aftab K,Gilani AH

    更新日期:1995-03-01 00:00:00

  • Interconverting flavonostilbenes with antibacterial activity from Sophora alopecuroides.

    abstract::Five flavonostilbenes (alopecurones H, I, J, K and L) and five known ones were isolated from roots of Sophora alopecuroides, in addition to ten other phenolic compounds. A non-enzymatic interconversion of the lavandulyl-substituted flavonostilbenes was observed among alopecurones A, H, I, and K through a Wessely-Moser...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2015.02.022

    authors: Wan CX,Luo JG,Ren XP,Kong LY

    更新日期:2015-08-01 00:00:00

  • Characterization of the 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase multigene family of Malus domestica Borkh.

    abstract::Two 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase (ACO) genes have been cloned from RNA isolated from leaf tissue of apple (Malus domestica cv. Royal Gala). The genes, designated MD-ACO2 (with an ORF of 990bp) and MD-ACO3 (966bp) have been compared with a previously cloned gene of apple, MD-ACO1 (with an ORF of ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2009.01.002

    authors: Binnie JE,McManus MT

    更新日期:2009-02-01 00:00:00

  • Dammarane-type saponins from Gynostemma pentaphyllum.

    abstract::Seven dammarane glycosides, gypenosides GC1 to GC7, together with ten known compounds, gypenosides V, XIV, XLII-XLVI, gynosaponins TN-1, -2, and gymnemaside VI, were isolated from the methanol extract of the aerial parts of Gynostemma pentaphyllum. Their structures were elucidated by both analysis of 1D and 2D NMR spe...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.04.003

    authors: Kim JH,Han YN

    更新日期:2011-08-01 00:00:00

  • Phenylpropanoid and phenylisoprenoid metabolites from Asteraceae species as inhibitors of protein carbonylation.

    abstract::Three phenolic antioxidant and anti-inflammatory compounds: 7-methylaromadendrin, isoprenylhydroquinone glucoside, and 3.5-dicaffeoylquinic acid methyl ester, all isolated from Western Mediterranean Asteraceae species, have been studied for their inhibitory activity against protein carbonylation, a harmful post-transl...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.06.005

    authors: Marín M,Giner RM,Recio MC,Máñez S

    更新日期:2011-10-01 00:00:00

  • Phylogeny, structural diversity and genome-wide expression analysis of fibrillin family genes in rice.

    abstract::Fibrillins (FBNs) constitute a plastid-lipid-associated protein family that plays a role in chloroplast development, lipids metabolism and stress responses in plants. Until now, FBNs have been functionally characterized in stability of thylakoid and responses to the different stress stimuli. Consequently, phylogeny, d...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2020.112377

    authors: Li J,Li X,Khatab AA,Xie G

    更新日期:2020-07-01 00:00:00

  • Dissection of the network of indolic defence compounds in Arabidopsis thaliana by multiple mutant analysis.

    abstract::Characteristic for cruciferous plants is the synthesis of a complex array of defence-related indolic compounds. In Arabidopsis, these include indol-3-ylmethyl glucosinolates (IMGs), as well as stress-inducible indole-3-carbaldehyde (ICHO)/indole-3-carboxylic acid (ICOOH) derivatives and camalexin. Key enzymes in the b...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2019.01.009

    authors: Müller TM,Böttcher C,Glawischnig E

    更新日期:2019-05-01 00:00:00

  • Withanolides from aerial parts of Nicandra physalodes.

    abstract::Twenty withanolides, including previously unknown nicanlodes A-M, were isolated from aerial parts of Nicandra physalodes. Their structural elucidations were unambiguously achieved through interpretation of extensive spectroscopic data (NMR and HRMS) and by comparison with literature data. Nicanlodes A and B have an un...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2017.02.009

    authors: Yu MY,Zhao GT,Liu JQ,Khan A,Peng XR,Zhou L,Dong JR,Li HZ,Qiu MH

    更新日期:2017-05-01 00:00:00

  • Sebestenoids A-D, BACE1 inhibitors from Cordia sebestena.

    abstract::Bioassay-guided fractionation of an extract prepared from the fruits of Cordia sebestena led to the isolation of sebestenoids A-D (1-4). Their structures were elucidated on the basis of extensive NMR experiments and mass spectroscopic measurements. Compounds 1-4 exhibited moderate inhibition of the aspartic protease B...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2010.09.008

    authors: Dai J,Sorribas A,Yoshida WY,Williams PG

    更新日期:2010-12-01 00:00:00

  • A previously undescribed phenylethanoid glycoside from Callicarpa kwangtungensis Chun acts as an agonist of the Na/K-ATPase signal transduction pathway.

    abstract::The new concept that Na/K-ATPase acts as a receptor prompted us to look for new ligands from Callicarpa kwangtungensis Chun. Using column chromatography, an undescribed phenethyl alcohol glycoside, callicarpanoside A, and an undescribed benzyl alcohol glycoside, callicarpanoside B, along with twelve known polyphenols ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2020.112577

    authors: Xu Y,Jiang X,Xu J,Qu W,Xie Z,Jiang RW,Feng F

    更新日期:2021-01-01 00:00:00

  • Phenylpropanoid glycosides from Scrophularia ningpoensis.

    abstract::Three phenylpropanoid glycosides named ningposides A (3-O-acetyl-2-O-feruloyl-alpha-L-rhamnopyranose), B (4-O-acetyl-2-O-feruloyl-alpha-L-rhamnopyranose) and C (3-O-acetyl-2-O-p-hydroxycinnamoyl-alpha-L-rhamnopyranose) along with the known compounds sibirioside A, cistanoside D, angoroside C, acteoside, decaffeoylacte...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00171-0

    authors: Li YM,Jiang SH,Gao WY,Zhu DY

    更新日期:2000-08-01 00:00:00

  • Diversity of fatty acid composition of symbiotic dinoflagellates in corals: evidence for the transfer of host PUFAs to the symbionts.

    abstract::High diversity of fatty acid (FA) composition of endosymbiotic dinoflagellates of the Symbiodinium group (zooxanthellae) isolated from different cnidarian groups has been found. To explain this diversity, FA composition of the total lipids of pure symbiont fractions (SF) and host cell tissue fractions (HF) isolated fr...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.02.012

    authors: Imbs AB,Yakovleva IM,Dautova TN,Bui LH,Jones P

    更新日期:2014-05-01 00:00:00