Abstract：
:Three phenolic antioxidant and anti-inflammatory compounds: 7-methylaromadendrin, isoprenylhydroquinone glucoside, and 3.5-dicaffeoylquinic acid methyl ester, all isolated from Western Mediterranean Asteraceae species, have been studied for their inhibitory activity against protein carbonylation, a harmful post-translational modification of peptide chains associated with degenerative diseases. All compounds have proven to be effective, with 50% inhibitory concentration (IC₅₀) values in the micromolar range, against bovine serum albumin carbonylation caused by hypochlorite, peroxynitrite, and phorbol ester-induced leukocyte oxidative burst.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Marín M,Giner RM,Recio MC,Máñez Sdoi
10.1016/j.phytochem.2011.06.005subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1821-5issue
14-15eissn
0031-9422issn
1873-3700pii
S0031-9422(11)00300-1journal_volume
72pub_type
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