Abstract:
:Acquisition and reversal of a memory task dependent on hippocampal integrity were assessed in rats following chronic corticosterone treatment. Young adult male rats were injected daily with corticosterone (10 mg/kg, SC) for 8 weeks. Memory was assessed during the last week of treatment with an elevated platform maze. During acquisition trials, corticosterone-treated rats did not differ from vehicle-treated controls in either the location of first hole chosen nor in the latency to locate the escape hole. In the reversal trials, when the position of the escape hole was rotated 135 degrees, both groups successfully reversed their responses without persevering towards the previously rewarded escape hole location. These findings suggest that, despite the probability of corticosterone-induced changes in hippocampal physiology, chronic corticosterone treatment does not adversely affect performance in a memory task dependent on hippocampal integrity.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Bardgett ME,Newcomer JW,Taylor GTdoi
10.1016/0031-9384(95)02172-8subject
Has Abstractpub_date
1996-06-01 00:00:00pages
1111-5issue
6eissn
0031-9384issn
1873-507Xpii
0031938495021728journal_volume
59pub_type
杂志文章abstract::A group of young adult females, who had or had not eaten breakfast, drank either a glucose drink or a placebo. Fasting was associated with poorer performance on the Brown-Petersen task, a test of memory. A glucose drink improved the memory of those who had fasted, although it did not influence those who had eaten brea...
journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0031-9384(99)00040-2
更新日期:1999-08-01 00:00:00
abstract::Previous studies from our laboratory have demonstrated that male and female rats exhibit a differential pattern of behavior in the elevated plus-maze as a function of age. In the present study, the influence of individual housing conditions on young animals treated with one of two classical anxioselective drugs, diaze...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00254-5
更新日期:1996-12-01 00:00:00
abstract::We previously reported that in male rats, 24 h of social housing with an associate male rat immediately following fear conditioning attenuated conditioned hyperthermia in response to an auditory conditioned stimulus. In this study, we investigated the time window and threshold of social housing where "social buffering...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.10.025
更新日期:2011-02-01 00:00:00
abstract::Plasma noradrenaline (NA), adrenaline (A) and corticosterone (CS) concentrations were determined simultaneously in permanently heart-cannulated rats before and during the performance of reinforced and nonreinforced (extinguished) operant behavior. Shortly before the experimental food-reinforced (VI 15-sec schedule) le...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90079-j
更新日期:1990-04-01 00:00:00
abstract::Neuropeptide gamma (NP gamma) is a 21 aminoacid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. NP gamma possesses higher affinity than NKA for central NK-2 receptors; it shows lower affinity for NK-1 receptors, however, it potently stimulates salivary secre...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)00071-p
更新日期:1995-09-01 00:00:00
abstract::Estrous synchrony was tested using 10 pairs of sibling female rats (Rattus norvegicus). A Monte Carlo bootstrap simulation was used to construct random control groups to avoid previous statistical errors and to test for significance when there are irregular cycles. The 10 pairs of females did not exhibit estrous synch...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(00)00395-4
更新日期:2001-01-01 00:00:00
abstract::This study was undertaken to investigate changes in ambulatory and drinking behavior, using the Gunma University-type special apparatus for continuous and direct measurement of ambulation and drinking in streptozotocin-induced diabetic rats (STZ, 60 mg/kg). Ambulatory activity of diabetic rats was significantly less t...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90366-c
更新日期:1990-06-01 00:00:00
abstract::Medroxyprogesterone acetate (MPA), a synthetic progestin with androgen-depleting activity, is used to treat the deviant sexual behavior of men. To investigate the effects of MPA in another anthropoid primate, 16 oppositely-sexed pairs of cynomolgus monkeys were observed in one-hour behavior tests during 15 successive ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90275-2
更新日期:1988-01-01 00:00:00
abstract::The performance of two experimental groups--one with lesions of the perforant paths projecting to the dorsal hippocampus (the D group) and one with lesions of the perforant paths to both the dorsal and ventral hippocampus (the DV group)--was compared with the performance of a lesioned control group and an intact contr...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(75)90210-3
更新日期:1975-10-01 00:00:00
abstract::Each of three monkeys was operantly conditioned to slow its heart, to exercise (lift weights) and to attenuate the tachycardia of exercise by combining these two skills. Each was further tested during beta-adrenergic blockade (atenolol), combined alpha-adrenergic blockade (prazosin) and beta-adrenergic blockade, or ch...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90058-v
更新日期:1991-02-01 00:00:00
abstract::The interaction of sucrose availability and oral self-administration of amphetamine was examined in 23 male Sprague-Dawley rats. Fourteen rats were given a 0.075 mg/ml amphetamine sulfate solution as their sole source of fluid and 9 rats were given water. Feeding conditions were alternated between weeks with both gran...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90312-5
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:The jiggle of the motor evoked potential (MEP) induced by transcranial magnetic stimulation (TMS) depends on a number of factors including the assessment of this stochastic signal by the method known as area under curve (AUC). We aim to ascertain the MEP findings assessed by the AUC method obtained from indiv...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.01.014
更新日期:2015-03-15 00:00:00
abstract::Chemoreception of foodstuff in the gut is performed by endocrine cells dispersed in the gut epithelium. They are bipolar cells extending an apical process to the gut lumen and releasing their messenger substances from the cell base in response to the apical stimuli. The cells share cell-biological features with neuron...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/0031-9384(91)90198-w
更新日期:1991-05-01 00:00:00
abstract::Obesity and chronic stress have been considered important public health problems that affect millions of people worldwide. Our aim was to analyze the effect of obesity associated with chronic stress on neurobehavioral parameters in female rats, considering that the association of these syndromes can enhance the negati...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.07.016
更新日期:2015-11-01 00:00:00
abstract::The amygdaloid complex appears to be an essential component in the neural systems mediating some forms of aversive Pavlovian conditioning. The relative contribution of this structure to acquisition and performance during fear conditioning was assessed by making temporary lesions in the amygdala prior to training or re...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90320-2
更新日期:1992-06-01 00:00:00
abstract::Avian and mammalian 'rapid eye movement' sleep (REM sleep) resemble each other in several aspects. However, the question of whether REM sleep has a shared evolutionary ancestry in birds and mammals has yet to be thoroughly explored. The brain regions and neurotransmitter systems involved in the generation of mammalian...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2005.12.003
更新日期:2006-03-30 00:00:00
abstract::Ethanolic extract of leaves of Morus alba L. (M. alba), known as white mulberry, was orally administered (100 mg/kg b.wt) for 8 weeks to female Wistar rats that were fed a high-cholesterol diet (HCD), to investigate the potential of M. alba leaves in attenuation of obesity, dyslipidemia, insulin resistance, and defici...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2018.12.010
更新日期:2019-03-15 00:00:00
abstract::In studies of experimentally induced retrograde amnesia (RA), as the interval between training and the amnestic treatment is lengthened, amnesia decreases (4). This temporal gradient for RA has been reported with a wide variety of amnestic agents, including RA produced by thermoregulatory disturbances (8). This tempor...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(99)00008-6
更新日期:1999-07-01 00:00:00
abstract::The temporal organization of masculine sexual behavior in rats is highly stereotyped; involving a sequence of mounts, intromissions and ejaculations. Sexual behavior has been described in exogamic and genetically manipulated rodent species. In this work, we compare the male sexual behavior of outbred Sprague-Dawley (S...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.10.030
更新日期:2016-01-01 00:00:00
abstract::Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.12.001
更新日期:2013-01-17 00:00:00
abstract::The activity-stress ulcer procedure consists of housing rats in running-wheel activity cages while at the same time, restricting their food intake to 1 hr per day. Male Wistar rats which had been habituated with ad lib feeding to the running-wheel cage environment for 3 days prior to the restricted feeding phase, deve...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90247-5
更新日期:1982-10-01 00:00:00
abstract::The present study investigated the effects of caffeine on memory for supraspan word lists. Twelve groups of male and female college students classified as high or low impulsive were administered (PO) 0 mg/kg, 2 mg/kg or 4 mg/kg of caffeine. Subjects listened to four word lists presented at a fast rate and four at a sl...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90170-2
更新日期:1985-07-01 00:00:00
abstract::The examples of "synergism" reported in the taste literature fit the common definition of the term but may merely reflect normal additivity in the taste system. That is, the perceived intensities of these "synergistic" mixtures exceed the sums of the perceived intensities of the unmixed taste components (addition of p...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(80)90066-9
更新日期:1980-06-01 00:00:00
abstract::Bulbectomy has been previously shown to produce the specific antidepressant-sensitive syndrome in C57Bl/6j, but not DBA/2j mice. The present study examined the effect of the depression on voluntary alcohol consumption. Alcohol consumption and alcohol preference (% of alcohol solution in total liquid) in a free-choice,...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90293-3
更新日期:1994-09-01 00:00:00
abstract::We tested whether cyclic estradiol treatment, like continuous estradiol treatment, is sufficient to normalize meal size and body weight in ovariectomized rats. In Experiment 1, adult Long-Evans rats were ovariectomized and subcutaneously injected with 0, 0.2, or 2.0 microg estradiol benzoate (EB) in sesame oil each Tu...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(99)00060-8
更新日期:1999-08-01 00:00:00
abstract::The requisite criteria for what constitutes a taste primary have not been established. Recent advances in understanding of the mechanisms and functions of taste have prompted suggestions for an expanded list of unique taste sensations, including fat, or more specifically, free fatty acids (FFA). A set of criteria are ...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2011.05.002
更新日期:2011-09-26 00:00:00
abstract::Body temperature (T(b)) and metabolic rate (O(2) consumption) were measured continuously in naked mole-rats. Circadian rhythms were observed for both parameters. Body temperature increased at the end of the light phase in a 12L:12D cycle in three of four animals. The remaining animal exhibited a freerunning rhythm of ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(00)00280-8
更新日期:2000-10-01 00:00:00
abstract::The objectives of the present study were to evaluate the suitability of potential biomarkers for maternal ability in cattle, and in addition to test the hypothesis that dairy cows have a less pronounced motherliness than beef cows. Therefore, maternal behavior of 20 Simmental beef-type (S) and 20 German Black Pied (da...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.10.030
更新日期:2015-02-01 00:00:00
abstract::Multiple theta cells in the dentate granule cell area of the hippocampal formation of the freely moving rabbit were analyzed during three behavioral conditions: (1) voluntary motor patterns, termed Type 1 theta behaviors; (2) automatic motor patterns, termed Type 2 LIA behaviors; (3) alert immobility with presentation...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(83)90104-x
更新日期:1983-07-01 00:00:00
abstract::Brief ether exposure induced high quality sexual receptivity in ovariectomized, estrogen-treated rats, presumably by increasing the secretion of adrenal progestins. Adrenalectomy completely blocked the effects of ether on this behavior. The onset of receptivity occurred 30--60 min following ether exposure; latencies m...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(77)90333-x
更新日期:1977-08-01 00:00:00