A chromatographic procedure for the purification of human plasma albumin.

abstract：:Anti-HBc is the most sensitive indicator of current or recent hepatitis B virus infection, hence its detection is valuable in laboratory diagnosis of the infection. Dane particles isolated from the plasma of a single chronic carrier and his autologous IgG labeled with 125I were utilized in a solid-phase sandwich radio...

journal_title：Vox sanguinis

authors： Vyas GN,Roberts IM

更新日期：1977-12-01 00:00:00

abstract：:We have used the Optical Character Recognition system B (OCR-B) for automatic identification of blood samples on the Groupamatic 360 and in connection with computerized donor file management and control of blood product processing. For the Groupamatic system a device was constructed that lifts that samples, and during...

journal_title：Vox sanguinis

authors： Haahti E,Leikola J,Ruikka S

更新日期：1981-03-01 00:00:00

abstract：:With regard to hemostasis and thrombosis, collagens are among the most important physiologic components of the extracellular matrix in their role as platelet activators. Differences in the rate of platelet activation markedly influence normal hemostasis and the pathological outcome of thrombosis. Thus, collagen recept...

journal_title：Vox sanguinis

authors： Kunicki TJ,Nugent DJ

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Practices in end-of-life platelet transfusions in haematologic malignancies are variable. Our aim was to describe the platelet transfusion burden and parameters linked to this indication in such a setting and thereby contribute to defining optimal practices. MATERIALS AND METHODS:From July 20...

journal_title：Vox sanguinis

authors： Moracchini J,Seigeot A,Angelot-Delettre F,Vienot A,Aubry R,Daguindau É,Deconinck E,Frache S,Tiberghien P

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND AND OBJECTIVES:ISO standards for blood bags do not adequately define and control the dimensions of blood bag transfer tubing. This lack of standardization presents potential difficulties when making sterile connections between the wide range of tubing that has evolved in the absence of such standards. We aim...

journal_title：Vox sanguinis

authors： Nightingale MJ,Lees B,Biset R,Mertens W

更新日期：2006-10-01 00:00:00

abstract：:The decline in the incidence of TAH from 1985-1990 was considerable and based on a variety of interventions that led to increasingly intensive scrutiny of potential donors. The decline in incidence observed since 1990, and particularly since 1992, has been truly extraordinary and based principally on the introduction ...

journal_title：Vox sanguinis

authors： Alter HJ

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Photochemical treatment (PCT) based on amotosalen and ultraviolet A light (UVA) demonstrated a wide range of pathogen inactivation. However, coagulation proteins are affected by this treatment. The aim of this study was to evaluate the coagulation parameters in apheresis plasma units after tha...

journal_title：Vox sanguinis

authors： de Valensart N,Rapaille A,Goossenaerts E,Sondag-Thull D,Deneys V

更新日期：2009-04-01 00:00:00

abstract：:The granulocyte immunofluorescence test (GIFT) is valuable for detecting allogeneic and autologous granulocyte antibodies. However, the original tube technique (macro GIFT) requires 50-100 microliters of serum and 10(6) granulocytes with time-consuming washing steps which cause cell loss. We report a modification (mic...

journal_title：Vox sanguinis

authors： Press C,Kline WE,Clay ME,McCullough J

更新日期：1985-01-01 00:00:00

abstract：:In vivo immune phagocytosis of neonatal monocytes was significantly correlated to the extent of maternal HLA immunization. Monocytes from all 15 neonates of mothers with HLA antibodies show reduced immune phagocytosis. In contrast, this holds true for monocytes from only 6 out of 13 neonates of mothers without detecta...

journal_title：Vox sanguinis

authors： Neppert J,Mueller-Eckhardt G,Heine O

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Leucocyte-derived cytokines accumulate in stored whole blood. Pre-storage leucocyte depletion has reduced cytokine levels and, consequently, febrile non-haemolytic transfusion reactions. As leucocyte filtration and component separation can be performed until 24 h after donation, we hypothesize...

journal_title：Vox sanguinis

authors： Chudziak D,Sireis W,Pfeiffer HU,Henschler R,Seifried E,Bönig H

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Photodynamic treatment using methylene blue (MB) and visible light is in routine use for pathogen inactivation of human plasma in different countries. Ambient and product temperature conditions for human plasma during production may vary between production sites. The influence of different temperature condit...

journal_title：Vox sanguinis

authors： Gravemann U,Handke W,Sumian C,Alvarez I,Reichenberg S,Müller TH,Seltsam A

更新日期：2018-05-01 00:00:00

abstract：:BOW is a 'new' low-frequency red-cell antigen, detected in 2 unrelated English blood donors, that is sensitive to alpha-chymotrypsin and pronase. Anti-BOW is present in many polyspecific reagents used to define low-frequency antigens. Red-cell groups of the proposita, R.B., and her family show that the BOW blood group...

journal_title：Vox sanguinis

authors： Chaves MA,Leak MR,Poole J,Giles CM

更新日期：1988-01-01 00:00:00

abstract：:The following substances were tested for their influence on granulocyte function: 8 sera that contained human granulocyte-specific alloantibodies against the antigens NA1, NA2 and NB1, two HLA antisera, and the monoclonal antibodies W6/32 and CLB-FcR-gran 1. The effects examined included spontaneous and directed migra...

journal_title：Vox sanguinis

authors： Bux J,Dickmann JO,Stockert U,Mueller-Eckhardt C

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In previous studies, we found that platelet microparticles (PMPs) bind to cord blood (CB) CD34+ cells and transfer adhesion molecules to them, which enhances their engraftment. Before applying this phenomenon in actual transplants, we investigated the effect of PMPs on cryopreserved CD34+ cell...

journal_title：Vox sanguinis

authors： Liu B,Chen JS,Cao M,Gu SL,Liao C,Li DZ,Zhong HZ

更新日期：2004-08-01 00:00:00

abstract：:The requirements of children undergoing transfusion should be considered as a distinct entity from those of adults. Neonates are particularly vulnerable and there have been concerns over infective or toxic risks to this group. Neonates may also have more acute side-effects as a result of their small blood volume. Most...

journal_title：Vox sanguinis

authors： New HV

更新日期：2006-01-01 00:00:00

abstract：:Alloimmune neonatal thrombocytopenia (ANT) may cause intracranial haemorrhage in utero as well as at delivery. Recent management has concentrated on attempts to minimise fetal thrombocytopenia and prevent its complications. This report describes further experience with the use of repeated intravascular transfusions of...

journal_title：Vox sanguinis

authors： Murphy MF,Pullon HW,Metcalfe P,Chapman JF,Jenkins E,Waters AH,Nicolaides KH,Mibashan RS

更新日期：1990-01-01 00:00:00

abstract：:We developed a photodynamic method to inactivate viruses in human fresh plasma. Single plasma bags were illuminated with visible light in the presence of low doses of phenothiazine dyes like methylene blue or toluidine blue. By this treatment the infectivity of different enveloped viruses including the causative agent...

journal_title：Vox sanguinis

authors： Lambrecht B,Mohr H,Knüver-Hopf J,Schmitt H

更新日期：1991-01-01 00:00:00

abstract：:A model of the Rh blood group system is proposed which is based on discontinuous gene structure. The R29 control subregion consists of a single exon flanked by introns. Following the R29 subregion, the R1 subregion exists as seven exon structures which alternate with introns. The expression of each exon is controlled ...

journal_title：Vox sanguinis

authors： Giorno R

更新日期：1981-01-01 00:00:00

abstract：:Forty-six subjects (44 HIV antibody-positive) with some degree of immune deficiency (at least TH/TS ratio below 1) were randomly distributed into 4 treatment groups. Each group was assigned to 1 of 4 products to be used exclusively for a 1-year period: 1 concentrate was of intermediate purity and not heat-treated, and...

journal_title：Vox sanguinis

authors： Allain JP,Frommel D,Bosser C,Gazengel C,Larrieu MJ,Sultan Y

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Blood Services of the UK permanently de-select men who have had sex with men (MSM) from donating blood. The rationale for this has been questioned. This article attempts to evaluate whether this selection criterion does contribute to blood safety. MATERIALS AND METHODS:Data about transfus...

journal_title：Vox sanguinis

authors： Soldan K,Sinka K

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:An association of white blood cell (WBC) reduction with decreased mortality was reported by one observational, before-and-after study. A meta-analysis was undertaken to examine whether this finding is supported by all the evidence currently available from before-and-after studies, and whether ...

journal_title：Vox sanguinis

authors： Vamvakas EC

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The clinical significance of immune thrombocytopenia (ITP) is mainly reflected by bleeding and/or bleeding risks, which, in some cases, cannot be adequately controlled by standard therapy. Tranexamic acid (TA) is increasingly used in preventing and reducing bleeding in several medical settings...

journal_title：Vox sanguinis

authors： Mayer B,Salama A

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Fetal RHD genotyping of cell-free maternal plasma DNA from RhD negative pregnant women can be used to guide targeted antenatal and postnatal anti-D prophylaxis for the prevention of RhD immunization. To assure the quality of clinical testing, we conducted an external quality assessment worksho...

journal_title：Vox sanguinis

authors： Clausen FB,Hellberg Å

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Baxter's methylene blue (MB) photoinactivation of fresh frozen plasma (FFP) is a method that effectively removes any intracellular potentially infectious agent, such as prions, by filtration combined with an improved photochemical virus inactivation on a single unit of FFP. The purpose of this study was to d...

journal_title：Vox sanguinis

authors： Simonsen AC,Sørensen H

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The ultimate goal was to generate an industrial-scale process suitable to produce a high-yield, safe and stable immunoglobulin G (IgG) preparation for intravenous administration, which is ready to use for customer convenience. This new liquid 10% IgG preparation (IGIV 10%) was compared to Gamm...

journal_title：Vox sanguinis

authors： Teschner W,Butterweck HA,Auer W,Muchitsch EM,Weber A,Liu SL,Wah PS,Schwarz HP

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and severity of and risk factors for thrombocytopenia at birth in neonates with red cell alloimmunization. STUDY DESIGN:All neonates with haemolytic disease of the foetus/newborn (HDFN) due to red cell alloimmunization admitted to our centre between January 2000 and September 2010 w...

journal_title：Vox sanguinis

authors： Rath ME,Smits-Wintjens VE,Oepkes D,van Zwet EW,van Kamp IL,Brand A,Walther FJ,Lopriore E

更新日期：2012-04-01 00:00:00

abstract：:OCTAPLAS is a cell-free standardized blood group specific human coagulation active plasma for transfusion. The viral safety is mainly based on the treatment with solvent/detergent. SD is known to irreversibly inactivate the lipid enveloped viruses including HIV 1 + 2, HBV and HCV and has been recommended both by Europ...

journal_title：Vox sanguinis

authors： Biesert L,Suhartono H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Antibodies to the core of hepatitis B virus (anti-HBc) are considered to be the best serologically reliable markers of hepatitis B virus (HBV) infection. Through a national epidemiological survey, two young and first-time blood donors, originating from HBV-endemic areas, were identified as HBV...

journal_title：Vox sanguinis

authors： Laperche S,Guitton C,Smilovici W,Courouce AM

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Despite improved methods for detecting bacterial contamination of blood products, bacterial sepsis remains a significant risk in blood transfusion. This study was undertaken to investigate whether adopting a different skin disinfection protocol could reduce the rate of bacterial contamination ...

journal_title：Vox sanguinis

authors： Lee CK,Ho PL,Chan NK,Mak A,Hong J,Lin CK

更新日期：2002-10-01 00:00:00

abstract：:There is an ongoing debate whether platelet concentrates (PCs) prepared from either whole-blood donations or by plateletpheresis are superior. Usage of these two product types varies greatly between countries and individual institutions. Some use mainly apheresis PCs; others prefer pooled PCs which are produced from w...

journal_title：Vox sanguinis

authors： Schrezenmeier H,Seifried E

更新日期：2010-07-01 00:00:00