Abstract:
INTRODUCTION:The rapid increase on life-expectancy represents a major challenge and economic burden for modern societies. Several studies have focused on the effects of polyunsaturated fatty acids (PUFA) upon the immune system; however less attention has been paid to the effects of monounsaturated fatty acids (MUFA). In this work we investigated the relationship of habitual consumption of different types of fatty acids with different immune parameters in the elderly. SUBJECTS AND METHODS:40 institutionalized elderly (76-95 y) and 35 home-living middle-age subjects (57-65 y) were recruited. Dietary intakes of macronutrients, fiber and fatty acids, as well as immune parameters such as serum cytokines levels (IL-10, TNF-α, IL-8, IL-17, TGF-β and IL-12), phagocytic activity and cytotoxic NK activity, were determined. RESULTS:Elderly subjects had a lower intake of total lipids. MUFA intake was significantly lower in the elderly group than in middle-age adults whilst the contrary was true for PUFA. MUFA intake in the elderly was found to be positively associated with IL-12 (β = 0.879) and TNF-α (β = 0.789) serum concentrations, whilst PUFA intake was inversely related to levels of IL-12 (β = -0.534). These associations were not observed in the middle-age group. CONCLUSION:MUFA intake may contribute to the pro-inflammatory status present in the elderly. It may be advisable to develop future nutrient recommendations specific for elderly taking into account immune parameters. :Introducción: El rápido aumento de la esperanza de vida en las sociedades desarrolladas representa un gran desafío y supone una elevada carga económica. Numerosos trabajos han estudiado los efectos de los ácidos grasos poliinsaturados (AGP) sobre el sistema inmune, sin embargo los efectos de los ácidos grasos monoinsaturados (AGM) han recibido mucha menos atención. En este trabajo se investigó la relación del consumo habitual de los diferentes tipos de ácidos grasos con diversos parámetros inmunológicos en ancianos. Individuos y métodos: Se reclutaron 40 ancianos institucionalizados (79-95 AÑOs) y 35 individuos de mediana edad (57-65 AÑOs) que residían en sus hogares. Se determinó la ingesta diaria de macronutrientes, fibra y ácidos grasos, así como diversos parámetros inmunes; niveles séricos de citoquinas (IL-10, TNF-α, IL-8, IL-17, TGF-β e IL-12), actividad fagocítica y actividad citotóxica de células NK. Resultados: Los voluntarios ancianos presentaron una menor ingesta de lípidos totales. La ingesta de AGM fue significativamente menor en el grupo de ancianos que en los adultos de mediana edad, mientras que lo contrario fue cierto para los AGP. La ingesta de AGM en ancianos se asoció positivamente con las concentraciones de IL-12 (β = 0,879) y TNF-α (β = 0,789), mientras que la ingesta de AGP mostró una relación inversa con los niveles de IL-12 (β = -0,534). Estas asociaciones no fueron observadas en el grupo de mediana edad. Conclusión: La ingesta de AGM podría contribuir al estado pro-inflamatorio presente en los ancianos. Sería aconsejable desarrollar recomendaciones nutricionales específicas para ancianos teniendo en cuenta parámetros inmunológicos.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
González S,López P,Margolles A,Suárez A,Patterson AM,Cuervo A,de los Reyes-Gavilán CG,Gueimonde Mdoi
10.3305/nh.2013.28.2.6183subject
Has Abstractpub_date
2013-03-01 00:00:00pages
474-8issue
2eissn
0212-1611issn
1699-5198journal_volume
28pub_type
杂志文章abstract:OBJECTIVES:The present case-control study was undertaken to elucidate the role of recent diet, specially in the influence of food groups, in the development of cancer of the breast. MATERIAL AND METHODS:A case-control study of breast cancer (BC) was conducted between April to November 1997 in Valencia (Spain). Cases w...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract:INTRODUCTION:Stature is an important variable in several indices of nutritional status that are applicable to elderly persons. However, stature is difficult or impossible to measure in elderly because they are often unable to maintain the standing position. A alternative is the use of estimated height from measurements...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.2.7618
更新日期:2014-10-16 00:00:00
abstract:INTRODUCTION:southern European, Middle Eastern, and North African countries bordering the Mediterranean share dietary habits characterized by moderation and a variety of foods, notably fruit and vegetables. These customs are becoming modified due to social and economic changes. An adequate intake of water and other dri...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9892
更新日期:2015-12-01 00:00:00
abstract:Introduction:Water intake has been proposed for weight loss; however, the evidence of its efficacy is limited. The aim of this study was to systematically review the randomized clinical trials that assessed the effect of water consumption on weight with a follow up ≥ 12 weeks. A systematic query-based search was perfor...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.02746
更新日期:2019-12-26 00:00:00
abstract:INTRODUCTION:We may define Modular Parenteral Nutrition (MPN) as parenteral nutrition (PN) mixtures obtained from adding different macronutrients to standard formulations (SPN) both binary (amino acids and glucose) and ternary (amino acids, lipids, and glucose). OBJECTIVES:The aim of this study is to demonstrate that ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
abstract:Introduction:Background: the legislation currently regulating the inclusion of Food for Special Medical Purposes (FSMP) among the benefits of the National Health System (SNS) was made approximately 15 years ago. The evolution of the technical characteristics of the FSMP justifies an analysis of the current regulation a...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03082
更新日期:2020-12-16 00:00:00
abstract:OBJECTIVE:The objectives of the study were to analyze the psychometric properties, factor structure and internal consistency of the Spanish version of the Food Craving Inventory (FCI-SP), as well as to determine its validity by evaluating the relationship of the FCI to different instruments. METHODS:The sample compris...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract:Introduction:For centuries the traditional ingredients of food patterns in Basque Country were millet, chestnuts, cabbage, beans, lentils, fish, pork and beef especially, as well as a variety of fruits such as apples, pears and grapes. Later, the potato replaced chestnuts, corn replaced millet and beans replaced broad ...
journal_title:Nutricion hospitalaria
pub_type: 历史文章,杂志文章
doi:10.20960/nh.02689
更新日期:2019-07-02 00:00:00
abstract:BACKGROUND:Obesity and the metabolic syndrome affect a considerable segment of the population worldwide, including health professionals. In fact, several studies have reported that physicians tend to have more cardiovascular risk factors than their patients. The present cross-sectional study assessed whether the Health...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.1.6185
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:the use of lipid emulsions together with glucose as a calorie source in parenteral nutrition has undisputed advantages. Their isotony and high calorie content mean they are essential for peripheric parenteral nutrition and in parenteral nutrition of long duration they are important in providing essential f...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract::The use of selenized yeast as enriched selenium supplements in human nutrition has become a topic of increasing interest over the last decade. The present study was designed with the aim to achieve a balance between selenium (Se) incorporation and optimal growth of yeast cells along with effect of Se enrichment on ant...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract:UNLABELLED:Enteral nutrition therapy (ENT) is an essential part in the management of critically ill patients, having a significant impact on these patients' clinical results. It can be administered on a continuous or intermittent basis using an infusion pump. There is a discussion on which of these techniques has the b...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,随机对照试验
doi:10.3305/nh.2014.29.3.7169
更新日期:2014-03-01 00:00:00
abstract::A retrospective study was carried out of all the Parenteral Nutrient Units (PNUs) prepared in the Pharmacy Service (PS) of an Area Hospital with 378 beds, over a four-year term (1988-1991), with the aim of describing the use of Parenteral Nutrition (PN) and to find out to what level it is adjusted to the established m...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract::Recent studies of dietary habits in children and adolescents performed in Spain show that a high percentage of the daily energy intake corresponds to fat (42.0-43.0%). These findings show an excessive contribution of saturated fatty acids and also a considerable supply of trans fatty acids. These compounds are formed ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::During the last half of the 20th century, Nutrition has evolved in a quick way based on the knowledge of both basic sciences as Biochemistry and Physiology and applied sciences as Epidemiology and Public Health. In that period the nutritional requirements for different population groups grouped by sex, age and physiol...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.20960/nh.2123
更新日期:2018-06-12 00:00:00
abstract::The reliability of the information collected in dietary assessment can be affected by different factors. One of the main sources of error in dietary assessment is misreporting which encompass under- and overreporting. Underreporting of food intake is one of the major problems in the assessment of habitual dietary inta...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.31.sup3.8760
更新日期:2015-02-26 00:00:00
abstract:Introduction:Introduction: currently, it is important to determine whether food frequency questionnaires (FFQ) are valid tools to collect information on usual diet in children. Objective: we evaluated the reproducibility and validity of the semi-quantitative FFQ used in a Spanish cohort of children aged 4-7 years. Meth...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03003
更新日期:2020-08-27 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Various experimental studies have shown that a deficient intake of zinc increases the proliferation of cells, the effect of carcinogens and the progression of colonic adenomas to carcinomas. The purpose of our study is to determine whether this relationship between zinc intake deficit and co...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract:INTRODUCTION:Necrotizing enterocolitis (NEC) is the most commonly acquired neonatal intraabdominal emergency and causes significant morbidity and mortality. A proposed strategy for the prevention of NEC in preterm infants is the administration of oral probiotics. The objective of the study is to analyze the efficacy an...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nutr hosp.v28in06.6901
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To describe the administration of drugs through nasogastric tubes by the nursing staff of a tertiary hospital and to identify the most common administration errors. METHODS:An observational study was carried out between November of 2010 and March of 2011. The study population was the nursing staff of the hos...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章
doi:10.3305/nh.2012.27.3.5747
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION:Body weight measurement is of critical importance when evaluating the nutritional status of patients entering a hospital. In some situations, such as the case of patients who are bedridden or in wheelchairs, these measurements cannot be obtained using standardized methods. We have designed and validated a ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.3.6455
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To analyze the psychological status of morbidly obese patients suffering changes after surgical procedure for weight reduction. METHODS:We analyze the weight loss in 100 morbidly obese patients (85 female, 15 male) after bariatric surgery (vertical banded gastroplasty). We correlated the percentage of weight...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract:INTRODUCTION:enteral nutrition therapy maintains and/or regains the nutritional status of the common patient in hospital settings, where anemia and malnutrition are food related and are very common diseases. OBJECTIVE:to determine and associate the presence of anemia and malnutrition in hospitalized patients with excl...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1628
更新日期:2018-06-22 00:00:00
abstract::The objective of this work was to determine whether the increase in serum GH, IGF1, glucose and insulin levels caused by the administration of hGH modifies the normal response of cholesterol and lipoproteins to surgical aggression. A prospective, randomized, and double blind study is carried out in 28 patients operate...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence of anaemia and the risk of haemoconcentration and its risk factors during all 3 trimesters of pregnancy in women in a Mediterranean area in the south of Europe. MATERIAL AND METHODS:Longitudinal study of 11,259 women whose pregnancies were monitored at primary care centres between ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.1045
更新日期:2018-01-10 00:00:00
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journal_title:Nutricion hospitalaria
pub_type: 杂志文章,多中心研究
doi:10.3305/nutr hosp.v28in06.6412
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION:breast milk, besides being a source of feeding for children, it can be a vehicle for transmission of some infectious diseases. AIM:to revise the main viral agents which can be acquired for children through breast milk and its possible clinical implication. MATERIAL:literature search was made in different...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2015.32.1.8794
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:the aging population has been accompanied by epidemiological changes of the Brazilian population, with the highlight being the continued growth of the prevalence of non-communicable chronic diseases especially cardiovascular or artery-coronary, resulting from changes in the lipid profile of the elderly. OBJ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.2.8875
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:the relationship between changes in energy intake (EI) over the last few decades and the trends towards of excess weight in children is still debated. OBJECTIVE:to examine the relationship between energy and macronutrient intakes with adipostity in children, controlling for cardiorespiratory fitness (CRF)...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.4.9185
更新日期:2015-10-01 00:00:00
abstract::Introducción: existen alteraciones frecuentes en la alimentación de la población infantil femenina, y especialmente en atletas de deportes estéticos por la presión ejercida para mantener un cuerpo.Objetivos: evaluar los aspectos nutricionales, antropométricos y la percepción del peso de niñas que realizan gimnasia rít...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.383
更新日期:2016-07-19 00:00:00