Abstract:
:To reveal the role of key elements present in the hair of breast cancer patients on cancer development, the levels of a number of elements in scalp hair samples of 82 people including healthy individuals, people suffering from benign breast disease, and breast cancer patients were measured by PIXE analysis. Pellets of hair samples were prepared and bombarded by 2.2 MeV proton beam of a 3-MV Van de Graaff accelerator. The number of incident ions hitting the sample was indirectly measured using the RBS spectrum of a thin Ag film placed in the beam path. The concentrations of S, Cl, K, Ca, Fe, and Cu in the hair of healthy individuals were in agreement with those observed in the hair of hyperplasia and cancer patients within standard deviations. However, a lower average level of zinc was found in samples from hyperplasia and breast cancer patients. Strong positive correlations were found between iron and potassium as well as between calcium and potassium in the cancer patients. These results could be of significance in the screening for breast cancer.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Gholizadeh N,Kabiri Z,Kakuee O,Saleh-Kotahi M,Changizi V,Fathollahi V,Oliaiy P,Omranipour Rdoi
10.1007/s12011-013-9671-2subject
Has Abstractpub_date
2013-06-01 00:00:00pages
105-10issue
1-3eissn
0163-4984issn
1559-0720journal_volume
153pub_type
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