Abstract:
:Manganese (Mn) is an essential element for normal development and bodily functions in humans. In the present study, we examined whether Mn supplementation can alter the serum lipid parameters and liver function in Ca-deficient ovariectomized (OVX) rats. Sixty female Sprague-Dawley rats (6 weeks) were divided into five groups and bred for 12 weeks: sham-operated control group (Sham), OVX Ca deficiency group (OLCa) with Ca-deficient diet (0.1% Ca modified AIN-93N diet), OVX Ca deficiency and Mn supplementation group (OLCaMn), OVX with adequate Ca group (OACa; 0.5% Ca AIN-93N diet), and OVX with adequate Ca and Mn supplementation group (OACaMn). A low Ca diet increased the liver weight and serum levels of GOT, GPT, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in OVX rats. Mn supplementation decreased these parameters in Ca-deficient OVX rat. The results of our study suggest Mn supplementation results in reductions of the blood cholesterol levels, which show an increase due to Ca deficiency in OVX rats.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Bae YJ,Choi MK,Kim MHdoi
10.1007/s12011-010-8714-1subject
Has Abstractpub_date
2011-06-01 00:00:00pages
224-31issue
1-3eissn
0163-4984issn
1559-0720journal_volume
141pub_type
杂志文章abstract::Cadmium (Cd) is an environmental toxicant and an inflammation-related xenobiotic. Selenium (Se) is a well-known nutritional trace element and a potent chemopreventive agent. The present study aimed to investigate the effect of Se on the cytotoxicity of Cd in bird immunocytes in vitro. Chicken splenic lymphocytes expos...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0354-z
更新日期:2015-11-01 00:00:00
abstract::Methylmercury (MeHg) is highly toxic, and its principal target tissue in human is the nervous system, which has made MeHg intoxication a public health concern for many decades. Portulaca oleraceae (purslane), a member of the Portulacaceae family, is widespread as a weed and has been ranked the eighth most common plant...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0546-6
更新日期:2016-07-01 00:00:00
abstract::In zinc deficiency, the function of leukocytes is impaired. However, the results of studies on the zinc concentration of blood cells in zinc deficiency are conflicting, probably in part because of technical and analytical problems. The aim of this study was to investigate, under standard conditions, the uptake of 65Zn...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783726
更新日期:1992-11-01 00:00:00
abstract::The effects of 10 wk of selenium (Se) supplementation (5 ppm) in drinking water on immune responses and resistance to a myocarditic Coxsackie virus B3 (CB3) infection were studied in female Balb/c mice. Se supplementation reduced CB3-induced mortality: at day 14 postinoculation, survival was 58% in the Se-treated grou...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785277
更新日期:1998-07-01 00:00:00
abstract::An experiment was conducted in a 3 × 3 (Cu × Zn) factorial experiment based on a completely randomized design to evaluate the effects of dietary copper and zinc on apparent mineral retention and serum biochemical indicators in young male mink on a corn-fish meal based diet. Animals were fed basal diets supplemented wi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0220-4
更新日期:2015-05-01 00:00:00
abstract::Experiments were conducted to determine whether the increased glutathione S-transferase (GSH-T) activity associated with selenium (Se) deficiency is necessarily related to losses in the activity of Se-dependent glutathione peroxidase (SeGSHpx) in chicks. Nutritional Se status was altered in two ways: by treatment with...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783792
更新日期:1993-05-01 00:00:00
abstract::Iron bioavailability seems to be regulated by vitamin A (VA) but the molecular events involved in this mechanism are not well understood. It is also known that retinoids mediate most of their function via interaction with retinoid receptors, which act as ligand-activated transcription factors controlling the expressio...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9397-6
更新日期:2012-10-01 00:00:00
abstract::Trace element involvement in wounds left to heal by secondary intention needs clarification. We have previously reported faster healing of wounds following acute surgery compared with elective excision of pilonidal sinus disease. The effect of topical zinc on the closure of the excisional wounds was mediocre compared ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9658-z
更新日期:2013-06-01 00:00:00
abstract::Numerous observations suggest a possible connection between the levels of Mg, Zn, Fe, and Zn and the incidence of depressive symptoms. Depression is two to three times more common in women than in men. The menopausal period is extremely conducive to depressive disorders. The aim of this study was to assess the severit...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0798-9
更新日期:2017-03-01 00:00:00
abstract::The exposure of toxic elements may directly or indirectly associate with different pathogenesis of heart diseases. In the present study, the association of arsenic (As), cadmium (Cd), cobalt (Co), lead (Pb), and nickel (Ni) in biological samples (whole blood and urine) and mortality from myocardial infarction (MI) pat...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8713-2
更新日期:2011-06-01 00:00:00
abstract::This study was initiated to examine if variations in the concentrations of cadmium (Cd) and lead (Pb) in water environment may affect metal levels in local foods and body burden of local residents in non-polluted areas in Japan. Two nationwide databases have been made available on concentrations of Cd in locally harve...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8436-4
更新日期:2010-03-01 00:00:00
abstract::The effects of selenium were investigated on three human colon cancer cell lines: Caco 2, HRT 18, and HT 29. At low concentrations (10-100 nM), selenium stimulated cell growth in serum-free medium. Thus, selenium is an essential trace element for cell proliferation. At higher concentrations, selenium inhibited cell gr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02919096
更新日期:1989-04-01 00:00:00
abstract::We investigated the possible correlation between the leptin concentration and the Zn/Cu ratio in the plasma of women with thyroid disorder. Forty women with hypothyroidism (n = 20) or hypothyroidism (n = 20) and 20 euthyroid controls were recruited. The results showed that the women with thyroid disorder (hypothyroidi...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/BTER:75:1-3:99
更新日期:2000-07-01 00:00:00
abstract::Arsenic (As), antimony (Sb), and bismuth (Bi) are metalloids that share similar chemical properties, the objective of this study was to characterize the uptake and accumulation of these metalloids by plants colonized on heavy contaminated sites in an old Sb mine. Sixty-five plant samples from seven species as well as ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9017-x
更新日期:2011-12-01 00:00:00
abstract::Neurodegeneration disorders are complex and multifaceted, leading to many chronic diseases, like Parkinson's disease (PD). Electrolytes imbalance has a significant role in the pathophysiology of neurological disorders, which might serve as a bio-indicator of these problems. In the present study, the disturbances of th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02399-y
更新日期:2020-09-22 00:00:00
abstract::Oxidative stress is involved in the pathogenesis of congestive heart failure (CHF). Some trace elements serve as antioxidant defenses. The purpose of this study was to analyze the effect of atrial fibrillation (AF) on zinc (Zn) and copper (Cu) levels in patients with advanced CHF. In this prospective study, serum Zn a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-8956-6
更新日期:2011-12-01 00:00:00
abstract::Quantitative analysis of follicular fluid and granulosa cells from small, medium and large antral atretic follicles of goat (Capra hircus) ovaries was conducted to study the alterations in trace elements viz zinc (Zn), copper (Cu), manganese (Mn), and iron (Fe). The zinc content was lower in the follicular fluid (0.99...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8700-7
更新日期:2011-06-01 00:00:00
abstract::Aluminum (Al) absorption seems to be very low, but many factors can enhance it in animals and humans. In the present study, we investigated the acute effect of Na citrate on Al absorption by monitoring Al levels in blood and several tissues. For this purpose, 18 Wistar male rats were divided into 3 groups: control, Al...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02778873
更新日期:1998-08-01 00:00:00
abstract::In a controlled animal experiment the effects of dietary subacute Zn deficiency on growth, Zn concentration, and tissue 42-K distribution were studied. Growth retardation caused lower body weight because both skeletal and heart muscle showed a reduction in cell mass. Zn concentrations were reduced in most tissues, how...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789301
更新日期:1994-12-01 00:00:00
abstract::Characterization of coffee terroirs is important to determine authenticity and provide confidence for consumers to select the right product. In this regard, Amhara Region, which is located at the northwestern part of Ethiopia, produces various local coffee types with distinct cup qualities. The coffees are, however, n...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01866-5
更新日期:2020-06-01 00:00:00
abstract::The growth of the protozoan Blepherisma is stimulated by Lanthanum (La) at concentrations as low as 0.32 ppm. In mice Yttrium (Y) and Ytterbium (Yb) are absorbed, accumulated, and metabolized. Both rare earth elements (RE) exhibit a high affinity for teeth and bones, accumulation occurs and metabolism is slow. In the ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02795448
更新日期:1988-09-01 00:00:00
abstract::Although fish consumption has positive health effects, metals accumulated in fish can cause human health risks. In this study, the levels of ten metals in rainbow trout (Oncorhynchus mykiss) farmed in the Keban Dam Reservoir, which has the biggest rainbow trout production capacity in Turkey, were determined and compar...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1156-2
更新日期:2018-07-01 00:00:00
abstract::Recently, several attempts have been made to use the phytopharmaceuticals from plant extracts as reducing, capping and stabilizing agents for the biomimetic synthesis of various metal nanoparticles conjugated to the phytopharmaceuticals. These biogenic metal nanoparticles are non-toxic and can be used as contrast agen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1287-0
更新日期:2018-11-01 00:00:00
abstract::In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8686-1
更新日期:2011-05-01 00:00:00
abstract::The chronic exposure to Aluminum (Al) may compromise different liver functions, mainly during the hepatic regeneration. The aim of this study is to investigate the interactions between the chronic i.p. exposure to Al and hepatic regeneration (HR) on bile flow and organic anion transport in experimental animals. For th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8234-4
更新日期:2009-02-01 00:00:00
abstract::As Cr(III) compounds have been shown to increase insulin sensitivity and decrease plasma cholesterol and triglycerides in rodent models of diabetes and insulin resistance and as colorectal cancer risk has been associated with insulin resistance and diabetes, the effects of the Cr(III) compound Cr3 ([Cr3O(O2CCH2CH3)6(H...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0346-z
更新日期:2015-11-01 00:00:00
abstract::Some studies have found that nano-sized titanium dioxide (nano-TiO2) has adverse effects on the male reproductive system. Blood-testis barrier (BTB), as one of the tightest blood-tissue restriction, is crucial to the male reproductive system. However, the potential effects on BTB and signaling pathway changes in testi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02404-4
更新日期:2020-09-29 00:00:00
abstract::The present investigation was carried out to determine the molybdenum (Mo) status of blood plasma and milk of lactating cows at the Livestock Experimental Station, Khizer abad, Sargodha, Pakistan. Blood and milk from the lactating cows were sampled periodically after every month during winter so as to examine the effe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8874-z
更新日期:2011-10-01 00:00:00
abstract::Diabetic osteoporosis (DOP) is a complication of diabetes, with the characteristics of bone mineral density (BMD) reduction and bone structure destruction. Zinc was reported has a benefit effect on postmenopausal osteoporosise, it was also has hypoglycemic effect, whether zinc was beneficial on diabetes-induced osteop...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01810-7
更新日期:2020-04-01 00:00:00
abstract::The effect of low copper and high zinc intakes on Cu,Zn-superoxide dismutase (Cu,Zn-SOD) activity and mammary tumorigenesis induced by 9,10-dimethyl-1,2-benzanthracene (DMBA) was investigated. Groups of 40 weanling female Sprague-Dawley rats were fed a modified AIN-76 diet containing the following (/kg diet): 1 mg Cu ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990343
更新日期:1991-07-01 00:00:00