Effects of comprehensive education protocol in decreasing pre-hospital stroke delay among Chinese urban community population.

Abstract:

BACKGROUND AND PURPOSE:Studies have shown that awareness of early stroke symptoms and the use of ambulances are two important factors in decreasing pre-hospital stroke delay. The purpose of this study is to evaluate a comprehensive educational stroke protocol in improving stroke response times. METHOD:Two urban communities in Beijing (population ≍50 000), matched in economic status and geography, were enrolled in this study. A comprehensive educational protocol, which included public lectures and distribution of instructive material for the community and its medical staff, was implemented from August 2008 to December 2010. Surveillance of new onset stroke in both communities was carried out during the same period. Pre-hospital delay time and percentage of patients using emergency medical services (EMS) were compared between the two communities. RESULTS:After comprehensive educational protocol, we found that: (i) pre-hospital delay (time from stroke symptom onset to hospital arrival) decreased from 180 to 79 minutes, (ii) the proportion of patients arriving within three hours of stroke onset increased from 55·8% to 80·4%, (iii) pre-hospital delay of stroke patients with symptoms of paralysis, numbness, and speech impediments was decreased, and (iv) the proportion of stroke patients calling for EMS increased from 50·4% to 60·7%. CONCLUSION:The comprehensive educational stroke protocol was significantly effective in decreasing pre-hospital stroke delay.

journal_name

Neurol Res

journal_title

Neurological research

authors

Chen S,Sun H,Zhao X,Fu P,Yan W,Yilong W,Hongyan J,Yan Z,Wenzhi W

doi

10.1179/1743132813Y.0000000203

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

522-8

issue

5

eissn

0161-6412

issn

1743-1328

pii

ner3124

journal_volume

35

pub_type

杂志文章
  • Selective and prolonged MRI enhancement by Mn-TPPS in an experimental rat brain tumour with peripheral benzodiazepine receptors.

    abstract::Synthesized Mn-TPPS, a paramagnetic metalloporphyrin, is expected to be a tumour specific contrast media for magnetic resonance (MR) imaging. We investigated the enhancing characteristics of Mn-TPPS using a transplanted rat C6 glioma model with peripheral type benzodiazepine (PBD) receptors since porphyrins are though...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1994.11740260

    authors: Ikezaki K,Nomura T,Takahashi M,Fritz-Zieroth B,Inamura T,Fukui M

    更新日期:1994-10-01 00:00:00

  • Music training causes long-term enhancement of preschool children's spatial-temporal reasoning.

    abstract::Predictions from a structured cortical model led us to test the hypothesis that music training enhances young children's spatial-temporal reasoning. Seventy-eight preschool children participated in this study. Thirty-four children received private piano keyboard lessons, 20 children received private computer lessons, ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1997.11740765

    authors: Rauscher FH,Shaw GL,Levine LJ,Wright EL,Dennis WR,Newcomb RL

    更新日期:1997-02-01 00:00:00

  • Ramipril prevents extracellular matrix accumulation in cerebral microvessels.

    abstract:OBJECTIVES:The stroke-prone spontaneously hypertensive rat is a genetic model of severe hypertension with secondary vascular alterations. The aim of this study was to determine the influence of chronic hypertension and ramipril treatment on the extracellular matrix in the cerebral microvasculature. METHODS:The study c...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164105X49256

    authors: Liebetrau M,Burggraf D,Büscher C,Linz W,Hamann GF

    更新日期:2005-07-01 00:00:00

  • Cerebellar contusion associated with type I Chiari malformation following supratentorial head trauma: case report.

    abstract::Acute presentation of Type I Chiari malformation in children is distinctly rare. An 11 year old male suffered a trauma to the right temporal-parietal region in a tobogganing accident resulting in an open depressed skull fracture. Radiographic evaluation included a Computed Tomographic scan which also demonstrated a si...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1998.11740599

    authors: Couldwell WT,Zhang W,Allen R,Arce D,Stillerman CB

    更新日期:1998-01-01 00:00:00

  • Microsurgical anatomy of the supratentorial arachnoidal trabecular membranes and cisterns.

    abstract::We examined the microsurgical anatomy of the supratentorial subarachnoid cisterns with a surgical microscope in 20 brains prepared using the immersion technique. The adult brains were immersed in Ringer's solution and air was injected into the subarachnoid cisterns while the brains remained submerged in solution. We i...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1994.11740266

    authors: Vinas FC,Fandino R,Dujovny M,Chavez V

    更新日期:1994-12-01 00:00:00

  • Recurrence of intracranial meningiomas: did better methods of diagnosis and surgical treatment change the outcome in the last 30 years?

    abstract:OBJECTIVE:Meningiomas are benign intracranial tumors growing from the arachnoid cap cells. Although their behavior is usually benign, they tend to recur even after total removal, and their recurrence is dependent on different aspects. METHODS:Between 1991 and 2002, 463 patients with an intracranial meningioma were ope...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313208X338043

    authors: Strassner C,Buhl R,Mehdorn HM

    更新日期:2009-06-01 00:00:00

  • Occipital petalia as a predictive imaging sign for transverse sinus dominance.

    abstract:OBJECTIVES:Occipital petalia is an anatomic description where one of the occipital lobes protrudes towards the contralateral side. Transverse sinus (TS) asymmetry might cause diagnostic challenges with regards to thrombotic or compressive pathologies involving these sinuses. In this study, we investigated the associati...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1560643

    authors: Arsava EY,Arsava EM,Oguz KK,Topcuoglu MA

    更新日期:2019-04-01 00:00:00

  • Simultaneous recording of tissue PCO2, interstitial pH and potassium activity in the rat cerebral cortex during anoxia and the subsequent recovery period.

    abstract::Tissue PCO2 (carbon dioxide tension) (PtCO2), interstitial H+ (H+e) and potassium activities (K+e) were monitored in the cerebral cortex of rats during and after 2-3 min of anoxia. Anoxia was associated with systemic hypotension and caused H+e (extracellular hydrogen ion activity) to increase from pH approximately equ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1989.11739882

    authors: Ohno M,Obrenovitch TP,Hartell N,Barratt S,Bachelard HS,Symon L

    更新日期:1989-09-01 00:00:00

  • Online assessment of brain tissue oxygen autoregulation in traumatic brain injury and subarachnoid hemorrhage.

    abstract::Monitoring of brain tissue oxygenation (ptiO2) enables early diagnosis of secondary cerebral ischemia and may guide a cerebral perfusion pressure (CPP) orientated therapy. The purpose of our study was to explain the concept of ptiO2-autoregulation, defined as the ability of the brain to maintain ptiO2 despite changes ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164103101201580

    authors: Soehle M,Jaeger M,Meixensberger J

    更新日期:2003-06-01 00:00:00

  • Asymptomatic circulating cerebral emboli and cerebral blood flow velocity under aspirin and ticlopidine in patients with cerebrovascular disease.

    abstract::Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/01616412.1996.11740450

    authors: Droste DW,Sonne M,Siemens HJ,Kaps M

    更新日期:1996-10-01 00:00:00

  • Effects of conditioning peripheral repetitive magnetic stimulation in patients with complex regional pain syndrome.

    abstract:OBJECTIVES:We tested whether repetitive magnetic stimulation (rMS) induces an afferent input to the spinocerebral tract in patients with complex regional pain syndrome (CRPS). METHODS:Cortical and spinal motor evoked potentials (cMEP and sMEP), as well as the contra- and ipsilateral silent period (cCSP and iCSP), were...

    journal_title:Neurological research

    pub_type: 临床试验,杂志文章

    doi:10.1179/016164105X17224

    authors: Krause P,Foerderreuther S,Straube A

    更新日期:2005-06-01 00:00:00

  • Feasibility and limitations of the rat model by C6 gliomas implanted at the subcutaneous region.

    abstract::Although rat models implanted with C6 glioma cells have been widely utilized for the assessment of new therapeutic modalities, a convenient in vivo model is still required. We implanted C6 glioma cells into the brains and the abdominal subcutaneous regions of Wistar rats, and evaluated the volumes of the growing tumor...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164102101200221

    authors: Watanabe K,Sakamoto M,Somiya M,Amin MR,Kamitani H,Watanabe T

    更新日期:2002-07-01 00:00:00

  • Laterality of seizure onset and the simple reaction time: revamping the Poffenberger's paradigm for seizure surgery.

    abstract:BACKGROUND:Crossed-uncrossed differentials (CUDs) are viewed as surrogates for interhemispheric transfer time (IHTT). Not uncommonly CUDs assume statistically significant negative values (inverted CUDs). This raises doubts of the accepted interpretation of CUDs, i.e. intra- and inter-hemispheric routings of signals in ...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/016164106X115107

    authors: Derakhshan I

    更新日期:2006-10-01 00:00:00

  • Amyotrophic lateral sclerosis immunoglobulins are ineffective in altering calcium influx through presynaptic voltage-sensitive calcium channels.

    abstract::Recent work has suggested that one factor in the etiology of the neuromuscular disease, amyotrophic lateral sclerosis (ALS), may be an autoimmune mechanism in which presynaptic voltage-sensitive calcium channels are an antigenic target. We have developed a fluorescence technique to measure rapid Ca2+ influx through pr...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1997.11740785

    authors: Thomas MM,Dunn SM

    更新日期:1997-04-01 00:00:00

  • Effects of popliteal illumination on cerebral near-infrared spectroscopy.

    abstract::The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164101101199388

    authors: Litscher G

    更新日期:2001-12-01 00:00:00

  • The relationship between brain microbleeds and homeostatic markers in the treatment of ischemic stroke.

    abstract:OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1517111

    authors: Altintas O,Niftaliyev E,Asil T

    更新日期:2018-12-01 00:00:00

  • Thyrotropin-releasing hormone and its receptor in the cerebellum of inferior olive destroyed rat brain.

    abstract::To study the pathophysiology of olivopontocerebellar atrophy (OPCA), we destroyed inferior olive nuclei of male Wistar rats using 3-acetyl pyridine (3-AP) + harmaline + niacinamide. These rats showed a sluggish and ataxic gait. To elucidate the relationship between thyrotropin releasing hormone (TRH) in the Purkinje c...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2000.11740690

    authors: Adachi K,Rhue BN,Li M,Izumi M,Osano H,Mitsuma T

    更新日期:2000-06-01 00:00:00

  • Oral creatine supplementation in Duchenne muscular dystrophy: a clinical and 31P magnetic resonance spectroscopy study.

    abstract::The decrease in intracellular creatine concentration in Duchenne muscular dystrophy may contribute to the deterioration of intracellular energy homeostasis and may thus be one of the factors aggravating muscle weakness and degeneration. Oral creatine supplementation should have potential in alleviating the clinical sy...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2000.11741051

    authors: Felber S,Skladal D,Wyss M,Kremser C,Koller A,Sperl W

    更新日期:2000-03-01 00:00:00

  • CART modulates beta-amyloid metabolism-associated enzymes and attenuates memory deficits in APP/PS1 mice.

    abstract:INTRODUCTION:Cocaine- and amphetamine-regulated transcript (CART) peptide has been demonstrated to exert neuroprotective effects in stroke and some neurodegeneration diseases. In current study, we investigated the protective effects and underlying mechanisms of CART in APP/PS1 mice. METHODS:The protein levels of CART,...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2017.1348689

    authors: Yin K,Jin J,Zhu X,Yu L,Wang S,Qian L,Han L,Xu Y

    更新日期:2017-10-01 00:00:00

  • Morphometric predictors of posterior circulation aneurysms risk rupture.

    abstract:OBJECTIVES:Intracranial aneurysms (IAs) of the posterior circulation (PC) rupture more frequently and their morbidity and mortality rates are higher compared to anterior circulation. Morphological parameters such as size ratio (SR), inflow angle and parent artery geometry are believed to contribute significantly in det...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132813Y.0000000306

    authors: Tykocki T,Nauman P,Dow Enko A

    更新日期:2014-08-01 00:00:00

  • Topical application of the hematostatic agent Surgiflo® could attenuate brain injury in experimental TBI mice.

    abstract:OBJECT:The pathologies resulting from traumatic brain injury (TBI) have been thoroughly studied, but rarely have the effects of bleeding and coagulation in the early stage of TBI been considered. In this study, we investigated the effects of topical Surgiflo® application on brain injury in experimental TBI mice using S...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2017.1330815

    authors: Guo D,Li D,Li J,Li Y,Hu X,Guan F,Yang B

    更新日期:2017-09-01 00:00:00

  • Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson's disease subjects.

    abstract:OBJECTIVES:Parkinson's disease (PD) afflicts approximately 1-2% of the population over 50 years of age. No cures or effective modifying treatments exist and clinical diagnosis is currently confounded by a lack of definitive biomarkers. We sought to discover potential biomarkers in the cerebrospinal fluid (CSF) of neuro...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132812Y.0000000063

    authors: Maarouf CL,Beach TG,Adler CH,Shill HA,Sabbagh MN,Wu T,Walker DG,Kokjohn TA,Roher AE,Arizona PD Consortium.

    更新日期:2012-09-01 00:00:00

  • The multifunctional role of IGF-1 in peripheral nerve regeneration.

    abstract::The elements of peripheral nerve regeneration comprise a complex combination of nerve growth, muscle satellite cells proliferation and differentiation and vessel growth. There is also increasing evidence that growth factors may act at multiple levels in the regenerative response. One such factor affecting multiple cel...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/016164104225013851

    authors: Rabinovsky ED

    更新日期:2004-03-01 00:00:00

  • Surgical resection and reconstruction after resection of tumors involving the sacropelvic region.

    abstract:OBJECTIVES:Surgical management of tumors in the sacropelvic region is a challenging field of spine surgery because of the region's complex local anatomy and biomechanics. Recent developments in anesthesia and intensive care have allowed us to perform extended surgeries focused on the en bloc resection of sacropelvic tu...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/1743132814Y.0000000370

    authors: Varga PP,Szoverfi Z,Lazary A

    更新日期:2014-06-01 00:00:00

  • WITHDRAWN: Activation of TLR4/NF-kappaB signaling pathway in early brain injury after subarachnoid hemorrhage.

    abstract::Ahead of Print article withdrawn by publisher. ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164109X12445616596283

    authors: Ma CX,Yin WN,Cai BW,He M,Wu J,Wang JY,Zeng Y,Ding JL,You C

    更新日期:2009-08-21 00:00:00

  • Hyperglycaemia protects against neuronal injury around experimental brain infarcts.

    abstract::Regional glucose utilization was measured in the rat brain after occlusion of the middle cerebral artery. Normoglycaemic rat had increased glucose use in the cerebral cortex adjacent to the infarct. A fraction of the nerve cells were irreversibly injured in this region. In hyperglycaemic rats, the glucose metabolism r...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1987.11739802

    authors: Nedergaard M,Gjedde A,Diemer NH

    更新日期:1987-12-01 00:00:00

  • A rat glioblastoma model with diffuse leptomeningeal gliomatosis induced by intracarotid injection of C6 glioma cells.

    abstract:OBJECTIVE:A reproducible brain tumor model using experimental animals is required to study biological behavior and develop more potent antineoplastic drugs and effective therapeutic modalities. In this work, we attempted to establish diffuse leptomeningeal gliomatosis in the rat by intracarotid injection of C6 glioma c...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X403904

    authors: Wasita B,Kamitani H,Kinoshita Y,Mamun MH,Watanabe T

    更新日期:2009-06-01 00:00:00

  • P300 as an index of implicit self-esteem.

    abstract::OBJECTIVE: To explore the neural substrates of implicit self-esteem in university students. METHODS: The subjects comprised four females and six males (aged 20-25 years). They were asked to finish the implicit association test (IAT) for implicit self-esteem while brain electrical activity was recorded at 64 scalp site...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X431138

    authors: Yang J,Zhang Q

    更新日期:2009-07-08 00:00:00

  • Distribution of artificial cerebral microemboli in stroke patients with patent foramen ovale.

    abstract:OBJECTIVES:Patent foramen ovale (PFO) is considered as an important risk factor for cerebrovascular diseases. Nevertheless, the relationship between the distribution of high-intensity transient signals (HITS), resulting from injection of air mixed with saline and detected by transcranial Doppler (TCD), and clinical cer...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164105X18458

    authors: Telman G,Kouperberg E,Sprecher E,Goldsher D,Yarnitsky D

    更新日期:2005-01-01 00:00:00

  • AST to ALT ratio and risk of hemorrhagic transformation in patients with acute ischemic stroke.

    abstract:BACKGROUND:Hemorrhagic transformation (HT) is a common complication of ischemic stroke. We performed this study to determine whether aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AAR) was related to HT, as well as compare the predictive values of AAR, ALT and AST for HT in patients with isch...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2020.1796403

    authors: Wang Y,Qiu K,Song Q,Cheng Y,Liu J,Liu M

    更新日期:2020-11-01 00:00:00