Abstract:
:The direct effects of nitrous oxide on left ventricular contractility and myocardial oxygen consumption (MVO2) in the ischemic isolated rat heart were studied. The rat heart was isolated and perfused by a Langendorf technique. The aortic stump was cannulated and the heart was perfused with Kumpeis solution bubbled with 95% O2 and 5% CO2 (control phase). A latex balloon was inserted into the left ventricle (LV) to measure LV pressures and dP/dt. Coronary flow was measured and MVO2 was calculated. After the control phase, perfusion pressure was decreased to induce global ischemia (ischemic phase). There were four groups of eight hearts each: control, nitrogen, nitrous oxide, and halothane groups. After 15 min of ischemic phase, the perfusion pressure was increased and the gas mixture was changed to the standard gas mixture (reperfusion phase). Nitrous oxide did not further depress myocardial contractility compared with nitrogen in the ischemic phase, and did not alter MVO2 in the ischemic phase compared with nitrogen. Halothane significantly depressed myocardial contractility and decreased MVO2 in the ischemic phase compared with the control.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Inada E,D'Ambra M,Laraia PJ,Philbin DM,Buckley MJdoi
10.1007/BF02514658subject
Has Abstractpub_date
1994-09-01 00:00:00pages
316-20issue
3eissn
0913-8668issn
1438-8359journal_volume
8pub_type
杂志文章abstract:PURPOSE:To evaluate the role of the phosphatidylinositol 3 kinase (PI3K)/protein kinase B (Akt)/hypoxia-inducible factor 1α (HIF-1α) signaling pathway in the protection by dexmedetomidine against lung ischemia-reperfusion injury (IRI) in rats. METHODS:Forty-eight male Sprague-Dawley rats weighing 250-350 g were random...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2214-1
更新日期:2016-10-01 00:00:00
abstract::Bronchial thermoplasty (BT) is a recently introduced bronchoscopic treatment for patients with asthma refractory to pharmacotherapy. Intraprocedural sedation management is important for successful performance of BT. However, the results of general anesthesia in patients undergoing BT have not been well described. The ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2485-9
更新日期:2018-06-01 00:00:00
abstract::The anesthesia information management system (AIMS) will be part of the future of healthcare. An electronic medical records system or AIMS will provide clear and concise information and have the potential to integrate information across the entire hospital system, improve quality of care, reduce errors, decrease risks...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-008-0643-1
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:Postoperative sore throat (POST) after general anesthesia with endotracheal intubation is a common and undesirable complication. In this study, we evaluated the combined effects of paracetamol and dexamethasone on the prevention of POST in patients after general anesthesia. METHODS:A total of 226 patients sche...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-017-2411-6
更新日期:2017-12-01 00:00:00
abstract::A male patient with Marfan syndrome underwent aortic root replacement and developed left ventricular (LV) failure. Four years later, he underwent aortic arch and aortic valve replacement. Thereafter, his LV failure progressed, and cardiogenic pulmonary edema (CPE) appeared, which we treated with extracorporeal LV assi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2163-8
更新日期:2016-08-01 00:00:00
abstract::Laparoscopic surgery has advanced remarkably in recent years, resulting in reduced morbidity and shorter hospital stay compared with open surgery. Despite challenges from the expanding array of laparoscopic procedures performed with the use of pneumoperitoneum on increasingly sick patients, anesthesia has remained lar...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-013-1736-z
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:We performed a multicenter, randomized, double-blind trial to assess the efficacy and safety of a single, fixed, intravenous dose of palonosetron (0.075 mg) in the treatment of established postoperative nausea and vomiting (PONV). METHODS:Three hundred and eighty-four patients who had at least one risk factors...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-014-1884-9
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:Remifentanil has been available in Japan for 3 years. The use of this new opioid is considered a useful adjuvant to general anesthesia. Knowing the exact cost-effectiveness of remifentanil should lead to improved anesthetic outcomes with a reasonable cost. METHODS:This single-blinded, prospective, randomized s...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-1006-2
更新日期:2010-12-01 00:00:00
abstract::We report an 83-year-old man with myasthenia gravis (MG) who developed respiratory depression after spinal anesthesia for transurethral laser enucleation of the prostate. He became less responsive after complained of dyspnea, with a decrease of SpO2 to 83% approximately 13 min after intrathecal administration of 0.5% ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02874-9
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVES:The incidence of postoperative shivering is known to be inversely associated with core body temperature. However, previous studies have pointed out that the threshold of shivering could be affected by peripheral temperature or anesthetic agents. These reports pointed specific drugs, though, anesthesia techni...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02763-1
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Several reports indicate that a neutrophil elastase inhibitor, sivelestat, may have prophylactic efficacy against a systemic inflammatory response after cardiovascular surgery with cardiopulmonary bypass (CPB). We evaluated the clinical pulmonary and cardiac effects of sivelestat. METHODS:We performed a retros...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0645-z
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:We aimed to introduce a simple, lightweight continuous positive airway pressure (CPAP)-delivery device for the nondependent lung during one-lung ventilation, to investigate how the type of three-way stopcocks, and the compliance and resistance of a test lung affect the relationship between the oxygen flow rate ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0681-8
更新日期:2009-01-01 00:00:00
abstract::Beta-adrenergic blockers (β-blockers) are clearly indicated for the long-term treatment of patients with systolic heart failure and post-acute myocardial infarction. Early small-scale studies reported their potential benefits for perioperative use; subsequent randomized controlled trials, however, failed to reproduce ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-019-02691-9
更新日期:2020-02-01 00:00:00
abstract::Isolated adrenocorticotropic hormone (ACTH) deficiency is an extremely rare disease in which ACTH-producing cells of the pituitary gland are selectively damaged. The resulting decline in ACTH production and secretion results in chronic secondary adrenocortical insufficiency. The patient in this case did not present wi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1118-3
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The relationship between preoperative hyperglycemia and postoperative acute kidney injury (AKI) occurrence in non-cardiac surgery including laparoscopic surgery remains unclear. This study aimed to assess the relationship between preoperative chronic hyperglycemia and postoperative AKI occurrence after a maj...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2551-3
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:The aim of this pilot study was to evaluate the diagnostic value of pleth variability index (PVI) to predict fluid responsiveness in newborn infants during surgery. METHODS:PVI was continuously recorded in 29 mechanically ventilated newborn infants during surgery, and episodes of clinically indicated volume ex...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1511-6
更新日期:2013-04-01 00:00:00
abstract::We tested hypertonic saline solution (HS) to determine its effectiveness in surgical procedures for prostatic hypertrophy. We randomly selected 40 patients undergoing elective transurethral resection of the prostate for either infusion of HS (3% NaCl) at 4ml·kg(-1)·min(-1) (HS group) or lactated Ringer's solution (LR)...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02471385
更新日期:1996-09-01 00:00:00
abstract::We report a case of diplopia during continuous epidural injection presumably caused by catheter migration. A 61-year-old woman underwent shoulder surgery under general anesthesia with cervical epidural anesthesia. The epidural catheter was placed in the C6-C7 epidural space with some difficulty before general anesthes...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1721-6
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:Painful neuropathic conditions of cancer pain often show little response to nonopioid and opioid analgesics but may be eased by antidepressants and anticonvulsants. Although gabapentin is effective in the treatment of neuropathic pain in patients with cancer, some patients experience intolerable side effects su...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-0913-6
更新日期:2010-06-01 00:00:00
abstract::We report three cases with systolic anterior motion (SAM) after mitral valve plasty. Preoperative mitral valve morphology is a risk factor for SAM. The morphological characteristics of SAM have been revealed in several studies. We found a small distance between coaptation and the interventricular septum in all cases, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1731-4
更新日期:2014-06-01 00:00:00
abstract::In the original publication of the article, the acknowledgment section was not included and provided in this correction. ...
journal_title:Journal of anesthesia
pub_type: 已发布勘误
doi:10.1007/s00540-020-02774-y
更新日期:2020-08-01 00:00:00
abstract::Perioperative positive airway pressure (PAP) is recommended by the American Society of Anesthesiologists for patients with obstructive sleep apnea, but a readily available and personalized intraoperative delivery system does not exist. We present the successful use of a patient's own nasal PAP machine in the operating...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2188-z
更新日期:2016-08-01 00:00:00
abstract::We describe a case of near-fatal asthma requiring extracorporeal membrane oxygenation (ECMO). The patient presented with severe respiratory distress, which was not responsive to conventional pharmacological therapy. The patient also failed to respond to mechanical ventilation and thus was placed on venovenous ECMO for...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1288-z
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Clinical histological studies demonstrate that the distribution of natural killer (NK) cells, other immune cells and μ-opioid receptors (MOR) within cancer tissue can predict cancer prognosis. No clinical study has evaluated whether anesthetic technique influences immune cell and MOR expression within human ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-018-2554-0
更新日期:2018-12-01 00:00:00
abstract::In this study induction of anesthesia using the single-breath technique with either enflurane or sevoflurane in oxygen was compared. Each group consisted of 16 unpremedicated volunteers who breathed approximately 1.7 minimum alveolar concentration (MAC) equivalents of either vapor. There were no significant difference...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514709
更新日期:1994-06-01 00:00:00
abstract::We experienced simultaneous coronary artery bypass grafting and cardiac pheochromocytoma resection under cardiopulmonary bypass in a 79-year-old woman with atherosclerotic angina. During manipulation of the tumor under cardiopulmonary bypass, the serum norepinephrine concentration increased to over seventy times the n...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-007-0549-3
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Stroke volume variation (SVV) is affected by many factors. Although elevated intra-abdominal pressure and a pneumoperitoneum have been shown to increase SVV in animals, a recent human study showed that SVV did not change as a pneumoperitoneum was established. However, we considered the results of this study que...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1963-y
更新日期:2015-08-01 00:00:00
abstract::Gasserian ganglion block is an established treatment for trigeminal neuralgia. A landmark approach assisted by X-ray fluoroscopy is the most common method; however, visualization of the foramen ovale is difficult in some cases. Here we report two cases in which a novel technique using modern computed tomography (CT) f...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-005-0307-3
更新日期:2005-01-01 00:00:00
abstract::The effect of famotidine on neonates was studied in 34 obstetric patients who underwent elective cesarean section. In the famotidine group, 20 mg of famotidine was intramuscularly injected at 60 min before induction of anesthesia, and 0.5 mg of atropine was injected at 30 min before induction. In the control group, on...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050276
更新日期:1991-07-01 00:00:00
abstract::The effect of verapamil on ventricular dysrhythmias was evaluated using two canine models. In one model, ventricular dysrhythmias were induced by 1% halothane-epinephrine (1.5 approximately 30 micro g/kg/min.) in 20 dogs (Group I). In the other model, ventricular dysrhythmias were induced by digoxin (0.1 approximately...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054080020028
更新日期:1988-03-01 00:00:00