Functional anatomical and behavioral consequences of dopamine receptor stimulation.

abstract：:Starling's law and the end-systolic pressure-volume relationship (ESPVR) reflect the effect of sarcomere length (SL) on the development of stress (sigma) and shortening by myocytes in the uniform ventricle. We show here that tetanic contractions of rat cardiac trabeculae exhibit a sigma-SL relationship at saturating [...

journal_title：Annals of the New York Academy of Sciences

authors： Ter Keurs HE,Shinozaki T,Zhang YM,Wakayama Y,Sugai Y,Kagaya Y,Miura M,Boyden PA,Stuyvers BD,Landesberg A

更新日期：2008-03-01 00:00:00

abstract：:SNAP-25 (synaptosomal-associated protein of 25 kDa) is a plasma membrane protein that, together with syntaxin and the synaptic vesicle protein VAMP/synaptobrevin, forms the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) docking complex for regulated exocytosis. SNAP-25 also modulates dif...

journal_title：Annals of the New York Academy of Sciences

authors： Corradini I,Verderio C,Sala M,Wilson MC,Matteoli M

更新日期：2009-01-01 00:00:00

abstract：:The apolipoprotein E (APOE) gene causes a major risk factor for the development of Alzheimer's disease (AD). To study the transcription control of the mouse (m) APOE gene, we first tested the promoter activity of a 721-base-pair (bp) 5'-flanking region, which is located 771 bp upstream from the translation initiation ...

journal_title：Annals of the New York Academy of Sciences

authors： Lahiri DK,Alley GM,Ge YW,Du Y

更新日期：2002-11-01 00:00:00

abstract：:Intracellular foreign protein (beta-galactosidase) expression in recombinant CHO cell lines in continuous culture was analyzed by developing a mathematical model that includes the effects of metabolic burden and cell cycle dependence of intracellular foreign protein expression. This combined growth kinetic and cell cy...

journal_title：Annals of the New York Academy of Sciences

authors： Gu MB,Todd P,Kompala DS

更新日期：1994-05-02 00:00:00

abstract：:Apoptosis plays a critical role in acetaminophen (AAP)-induced hepatic injury, since inhibiting apoptosis also prevents the development of acute liver failure. In this study, the mechanism of apoptosis induction by AAP was investigated in the human hepatoblastoma cell line HuH7. AAP caused marked cytotoxicity in HuH7 ...

journal_title：Annals of the New York Academy of Sciences

authors： Kass GE,Macanas-Pirard P,Lee PC,Hinton RH

更新日期：2003-12-01 00:00:00

abstract：:Two chemical classes of flavonoids, the flavan-3-ols (catechins and proanthocyanidins) and the anthocyanins, are the natural antioxidants present at the highest concentration in red grape and wine. In the berry, the anthocyanins are localized in the skins, similarly to other highly bioactive phenolics of grape such as...

journal_title：Annals of the New York Academy of Sciences

authors： Mattivi F,Zulian C,Nicolini G,Valenti L

更新日期：2002-05-01 00:00:00

abstract：:The role of dopaminergic activity in susceptibility of methamphetamine (MAP) psychosis (flashbacks) to subsequent spontaneous recurrences was studied. Plasma monoamine metabolite levels were assayed in 23 flashbackers, of whom 10 experienced a single flashback, 8 exhibited subsequent flashbacks and 5 with the last epi...

journal_title：Annals of the New York Academy of Sciences

authors： Yui K,Goto K,Ikemoto S

更新日期：2004-10-01 00:00:00

abstract：:The effects on ex vivo LDL resistance to oxidation and biomarkers of in vivo oxidative stress in response to 3-month dietary vitamin E restriction to 25% of recommended intake and 2-month unrestricted dietary intake and supplementation with 800 IU/d were studied in 100 healthy, nonsmoking 20-75-year-old volunteers. Si...

journal_title：Annals of the New York Academy of Sciences

authors： Winklhofer-Roob BM,Meinitzer A,Maritschnegg M,Roob JM,Khoschsorur G,Ribalta J,Sundl I,Wuga S,Wonisch W,Tiran B,Rock E,VITAGE Study Group.

更新日期：2004-12-01 00:00:00

abstract：:Rat IgM and IgG was determined by mechanized "sandwich" enzyme-linked immunosorbent assay (ELISA) using peroxidase labeled anti-rat-IgM and -IgG. Linear ranges in standard curves of a reference rat serum had a slope similar to the slopes found with sera of 25 rats of various age. IgM and IgG measurements by ELISA in t...

journal_title：Annals of the New York Academy of Sciences

authors： Vos JG,Buys J,Beekhof P,Hagenaars AM

更新日期：1979-05-31 00:00:00

abstract：:The article describes the process of planning the Memorial of Disappeared Detained Citizens in the City of Montevideo, Uruguay, the construction of which was completed in January 2003. It explores the role that memory, planning, and reconciliation carried out in the public realm can play in the context of an urban env...

journal_title：Annals of the New York Academy of Sciences

authors： Kohen M

更新日期：2004-06-01 00:00:00

abstract：:Reducing emissions from deforestation and forest degradation (REDD+) provides financial compensation to land owners who avoid converting standing forests to other land uses. In this paper, we review the main opportunities and challenges for REDD+ implementation, including expectations for REDD+ to deliver on multiple ...

journal_title：Annals of the New York Academy of Sciences

authors： Venter O,Koh LP

更新日期：2012-02-01 00:00:00

abstract：:We have verified that wild birds can become conditioned to reject naturally toxic insects either visually (experiment 1) or by taste (experiment 2). We have also verified, however, that unconditioned taste rejection of noxious chemicals by wild birds also occurs (experiment 3). Such unconditioned responses to the apos...

journal_title：Annals of the New York Academy of Sciences

authors： Brower LP,Fink LS

更新日期：1985-01-01 00:00:00

abstract：:Hematopoietic development in the mammal can be represented as a numerically expanding hierarchy of cell populations that are progressively restricted in their self-renewal and differentiation abilities. Classical functional studies have now been extended to provide exact physical descriptions of various stages in the ...

journal_title：Annals of the New York Academy of Sciences

authors： Lemischka I

更新日期：1999-04-30 00:00:00

abstract：:According to the fetal origin of adult diseases hypothesis, the intrauterine environment through developmental plasticity may permanently influence long-term health and disease. Therefore, intrauterine growth restriction (IUGR), due either to maternal, placental, or genetic factors, may permanently alter the endocrine...

journal_title：Annals of the New York Academy of Sciences

authors： Kanaka-Gantenbein C

更新日期：2010-09-01 00:00:00

abstract：:In this note epistemological problems in general theories about living systems are considered; in particular, the question of hidden connections between different areas of experience, such as folk biology and scientific biology, and hidden connections between central concepts of theoretical biology, such as function, ...

journal_title：Annals of the New York Academy of Sciences

authors： Emmeche C

更新日期：2000-01-01 00:00:00

abstract：:Neurotrophic factors are secreted peptides that when interacting with specific classes of membrane receptors activate intracellular signaling cascades that prevents neuronal death during embryonic development. The establishment of gene-targeted null mutant mice for the neurotrophic factors, brain-derived neurotrophic ...

journal_title：Annals of the New York Academy of Sciences

authors： Agerman K,Canlon B,Duan M,Ernfors P

更新日期：1999-11-28 00:00:00

abstract：:In this chapter, we examine the possibility that negative emotions contribute to the relationship between socioeconomic status (SES) and health. A model of the associations among SES, emotion, and health is presented first. We then review the evidence for this model, showing associations of SES with depression, hopele...

journal_title：Annals of the New York Academy of Sciences

authors： Gallo LC,Matthews KA

更新日期：1999-01-01 00:00:00

abstract：:Estrogen has clearly been shown to decrease bone loss and frequency of osteoporotic fractures. Calcitonin has been shown in several studies to reduce the rate of bone loss, although no data are yet available demonstrating a reduction in fracture frequency. Studies of osteoporosis intrinsically assume that prevention o...

journal_title：Annals of the New York Academy of Sciences

authors： Lindsay R,Cosman F

更新日期：1990-01-01 00:00:00

abstract：:The question addressed in this paper is whether the human amygdala processes threat-related stimuli independent of selective attention. This is considered from a functional neuroimaging perspective, describing studies in normal volunteers and patients with brain lesions. The conclusion is that the evidence for such au...

journal_title：Annals of the New York Academy of Sciences

authors： Dolan RJ,Vuilleumier P

更新日期：2003-04-01 00:00:00

abstract：:Effective emotion regulation may promote resilience and preschool classroom adjustment by supporting adaptive peer interactions and engagement in learning activities. We investigated how hypothalamus-pituitary-adrenal axis (HPA) regulation, cardiac reactivity, and classroom emotion displays related to adjustment among...

journal_title：Annals of the New York Academy of Sciences

authors： Miller AL,Seifer R,Stroud L,Sheinkopf SJ,Dickstein S

更新日期：2006-12-01 00:00:00

abstract：:Using a newly developed algorithm in conjunction with the front tracking scheme, we have evaluated the transport associated with a deformable bubble moving in a tube in the presence of a soluble or an insoluble surfactant. Such evaluations are useful to the understanding of gas embolism--a common syndrome for decompre...

journal_title：Annals of the New York Academy of Sciences

authors： Ayyaswamy PS,Zhang J,Eckmann DM

更新日期：2006-09-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic joint inflammation and continuous immune cell infiltration in the synovium. These changes are linked to inflammatory cytokine release, leading to eventual destruction of cartilage and bone. During the last decade new therapeutic modalities ha...

journal_title：Annals of the New York Academy of Sciences

authors： Marti L,Golmia R,Golmia AP,Paes AT,Guilhen DD,Moreira-Filho CA,Scheinberg M

更新日期：2009-09-01 00:00:00

abstract：:Bioterrorism includes possible use of Weapons of Mass Destruction (WMD), preferably biological agents, by non-state terrorist groups as well as criminal clusters. The threat from terrorists to utilize biological agents to achieve goals is not new, but the threshold to realize the threats seems to be lower than previou...

journal_title：Annals of the New York Academy of Sciences

authors： Sandström G

更新日期：2000-01-01 00:00:00

abstract：:Increasing evidence indicates that several mechanisms, associated or not with antioxidant actions, are involved in the effects of flavonoids on health. Flavonoid-rich beverages, foods, and extracts, as well as pure flavonoids are studied for the prevention and/or amelioration of metabolic syndrome (MS) and MS-associat...

journal_title：Annals of the New York Academy of Sciences

authors： Galleano M,Calabro V,Prince PD,Litterio MC,Piotrkowski B,Vazquez-Prieto MA,Miatello RM,Oteiza PI,Fraga CG

更新日期：2012-07-01 00:00:00

abstract：:Purified human urinary CSF-1 was used for production of polyclonal CSF antibodies in rabbits. The purified CSF was iodinated by a modified chloramine-T technique with retention of biologic activity. Dilutions of anti-CSF were reacted with 15,000 cpm of 125I-CSF in EDTA-phosphate buffer for 48 hr. Sheep antirabbit seru...

journal_title：Annals of the New York Academy of Sciences

authors： Shadduck RK,Waheed A

更新日期：1989-01-01 00:00:00

abstract：:Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder of the neuromuscular synapse. About half of LEMS patients have an associated small cell lung carcinoma (SCLC), which is usually detected after diagnosis of LEMS. This short review summarizes clinical and serological markers shown to predict the presenc...

journal_title：Annals of the New York Academy of Sciences

authors： Lipka AF,Verschuuren JJ,Titulaer MJ

更新日期：2012-12-01 00:00:00

abstract：:Cold-restraint stress reduces gastric blood flow and produces acute gastric ulcers. We studied the role of Angiotensin II (Ang II) on gastric blood flow and gastric ulceration during stress. Spontaneously hypertensive rats, a stress-sensitive strain, were pretreated for 14 days with the AT(1) receptor antagonist cande...

journal_title：Annals of the New York Academy of Sciences

authors： Bregonzio C,Armando I,Ando H,Jezova M,Baiardi G,Saavedra JM

更新日期：2004-06-01 00:00:00

abstract：:The cardiac myofilaments consist of a highly ordered assembly of proteins that collectively generate force in a calcium-dependent manner. Defects in myofilament function and its regulation have been implicated in various forms of acquired and inherited human heart disease. For example, during cardiac ischemia, cardiac...

journal_title：Annals of the New York Academy of Sciences

authors： Day S,Davis J,Westfall M,Metzger J

更新日期：2006-10-01 00:00:00

abstract：:Female mosquitoes gorge on vertebrate blood, a rich nutrient source for developing eggs, but gorging meals increase the risk of predation. Mosquitoes are quick to reduce the flight payload with a potent diuresis. Diuretic peptides of the insect kinin family induce a tenfold reduction in the paracellular resistance of ...

journal_title：Annals of the New York Academy of Sciences

authors： Beyenbach KW

更新日期：2012-07-01 00:00:00

abstract：:The endothelial cells cultured in collagen gel caused upregulation of KDR expression, which resulted in an increase in tube formation. Endothelial cells exposed to high glucose (33 mmol/l) for 30 days increased the tube formation induced by VEGF, but not by serum and bFGF. Immunohistochemical study showed that KDR exp...

journal_title：Annals of the New York Academy of Sciences

authors： Murota SI,Onodera M,Morita I

更新日期：2000-05-01 00:00:00