Automated segmentation of anatomic regions in chest radiographs using an adaptive-sized hybrid neural network.

Abstract:

:The purposes of this research are to investigate the effectiveness of our novel image features for segmentation of anatomic regions such as the lungs and the mediastinum in chest radiographs and to develop an automatic computerized method for image processing. A total of 85 screening chest radiographs from Johns Hopkins University Hospital were digitized to 2 K by 2.5 K pixels with 12 bit gray scale. To reduce the amount of information, the images were smoothed and subsampled to 256 by 310 pixels with 8 bit. The determination approach consists of classifying each pixel into two anatomic classes (lung and others) on the basis of several image features: (1) relative pixel address (Rx, Ry) based on lung edges extracted through image processing using profile, (2) density normalized from lungs and mediastinum density, and (3) histogram equalized entropy. The combinations of image features were evaluated using an adaptive-sized hybrid neural network consisting of an input, a hidden, and an output layer. Fourteen images were used for the training of the neural network and the remaining 71 images for testing. Using four features of relative address (Rx, Ry), normalized density, and histogram equalized entropy, the neural networks classified lungs at 92% accuracy against test images following the same rules as for the training images.

journal_name

Med Phys

journal_title

Medical physics

authors

Tsujii O,Freedman MT,Mun SK

doi

10.1118/1.598277

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

998-1007

issue

6

eissn

0094-2405

issn

2473-4209

journal_volume

25

pub_type

杂志文章
  • Tight-frame based iterative image reconstruction for spectral breast CT.

    abstract:PURPOSE:To investigate tight-frame based iterative reconstruction (TFIR) technique for spectral breast computed tomography (CT) using fewer projections while achieving greater image quality. METHODS:The experimental data were acquired with a fan-beam breast CT system based on a cadmium zinc telluride photon-counting d...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4790468

    authors: Zhao B,Gao H,Ding H,Molloi S

    更新日期:2013-03-01 00:00:00

  • GLAaS: an absolute dose calibration algorithm for an amorphous silicon portal imager. Applications to IMRT verifications.

    abstract::A new calibration algorithm (GLAaS) to derive absolute dose maps from images acquired with the Varian PV-aS500 electronic portal imager (based on amorphous silicon detectors) has been developed incorporating the dependence of detector response on primary and transmitted radiation and on field size. Detector calibratio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2218314

    authors: Nicolini G,Fogliata A,Vanetti E,Clivio A,Cozzi L

    更新日期:2006-08-01 00:00:00

  • SU-E-I-38: Optimizing CT Slice Width Measurements.

    abstract:PURPOSE:For almost four decades bead and wire ramps have been used in the evaluation of slice width as part of QA testing for CT scanners. While each of these approaches have been recognized and accepted as reliable, in this paper we investigate the differences, advantages and limitations of these tools. Moreover, we s...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734753

    authors: Marteinsdóttir M,Olafsdottir H,Fredriksson J,Andresson A,Healy A,Kristbjornsson A,Kristinsson S,Levy J,Goodenough D

    更新日期:2012-06-01 00:00:00

  • Evaluation of inherent gray-level dynamic range in a digital image using the runs test and join-count statistics.

    abstract::The dynamic range of the gray level of a digital image is limited by the noise it contains. Two statistical methods called "runs test" and "join-count statistic" are used to measure the noise level in a digital image. A residual image is formed by subtracting an original image from its smoothed version. Theoretically,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597058

    authors: Chuang KS,Huang HK

    更新日期:1993-01-01 00:00:00

  • Design for an accelerator-based orthogonal epithermal neutron beam for boron neutron capture therapy.

    abstract::This paper is concerned with the proposed Birmingham accelerator-based epithermal neutron beam for boron neutron capture therapy (BNCT). In particular, the option of producing a therapy beam at an orthogonal direction to the incoming protons is considered. Monte Carlo radiation transport simulations, both with and wit...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598479

    authors: Allen DA,Beynon TD,Green S

    更新日期:1999-01-01 00:00:00

  • Geometry optimization of electrically floating PET inserts for improved RF penetration for a 3 T MRI system.

    abstract:PURPOSE:An electrically floating radio frequency (RF) shielded PET insert with individual PET detectors shielded by separate Faraday cages enables the MRI built-in body RF coil to be used at least as an RF transmitter, in which the RF field penetrates the imaging region inside the PET ring through the narrow gaps betwe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13132

    authors: Akram MSH,Levin CS,Obata T,Hirumi G,Yamaya T

    更新日期:2018-10-01 00:00:00

  • Acceptance testing and quality assurance of automated scanning film densitometers used in the dosimetry of electron and photon therapy beams.

    abstract::Scanning film densitometry routinely used for obtaining dosimetric information about therapy treatment beams is subject to several sources of inaccuracies. The most significant of these are described and appropriate methods of testing are presented. This establishes the need for adequate acceptance testing followed by...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595407

    authors: Holmes TW,McCullough EC

    更新日期:1983-09-01 00:00:00

  • Addendum to the AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon beams.

    abstract::An addendum to the AAPM's TG-51 protocol for the determination of absorbed dose to water in megavoltage photon beams is presented. This addendum continues the procedure laid out in TG-51 but new kQ data for photon beams, based on Monte Carlo simulations, are presented and recommendations are given to improve the accur...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4866223

    authors: McEwen M,DeWerd L,Ibbott G,Followill D,Rogers DW,Seltzer S,Seuntjens J

    更新日期:2014-04-01 00:00:00

  • MO-F-BRCD-01: Stereotactic Body Radiation Therapy: Updates on Clinical, Biological, and Physics/QA:SBRT (Part 1): Biological and Clinical Updates.

    abstract::Stereotactic Body Radiation Therapy (SBRT) is an important form of cancer therapy with increasingly broad application across a spectrum of tumor types in primary and metastatic settings. In this presentation the radiation biology, clinical experience from various trials, and cautionary updates on normal tissue toleran...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735812

    authors: Read P

    更新日期:2012-06-01 00:00:00

  • Transrectal ultrasound based prostate volume determination: is the frustum algorithm more accurate than planimetry?

    abstract:PURPOSE:To compare reconstructed volumes calculated via planimetry and frustum algorithms in the context of stepped transrectal ultrasound (US) imaging, and to estimate the reconstruction error for prostate volumes. METHODS:Prostate contours for 40 permanent implant patients were delineated on magnetic resonance (MR) ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4789920

    authors: Liu D,Usmani N,Sloboda RS

    更新日期:2013-03-01 00:00:00

  • Verification of IMRT dose distributions using a water beam imaging system.

    abstract::A water beam imaging system (WBIS) has been developed and used to verify dose distributions for intensity modulated radiotherapy using dynamic multileaf collimator. This system consisted of a water container, a scintillator screen, a charge-coupled device camera, and a portable personal computer. The scintillation ima...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1413519

    authors: Li JS,Boyer AL,Ma CM

    更新日期:2001-12-01 00:00:00

  • Investigating energy deposition in glandular tissues for mammography using multiscale Monte Carlo simulations.

    abstract:PURPOSE:To investigate energy deposition in glandular tissues of the breast on macro- and microscopic length scales in the context of mammography. METHODS:Multiscale mammography models of breasts are developed, which include segmented, voxelized macroscopic tissue structure as well as nine regions of interest (ROIs) e...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13372

    authors: Oliver PAK,Thomson RM

    更新日期:2019-03-01 00:00:00

  • Volumetric breast density evaluation from ultrasound tomography images.

    abstract::Previous ultrasound tomography work conducted by our group showed a direct correlation between measured sound speed and physical density in vitro, and increased in vivo sound speed with increasing mammographic density, a known risk factor for breast cancer. Building on these empirical results, the purpose of this work...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2964092

    authors: Glide-Hurst CK,Duric N,Littrup P

    更新日期:2008-09-01 00:00:00

  • Toward consensus on quantitative assessment of medical imaging systems.

    abstract::Consensus has been developing over the past few decades on a number of measurements required for the laboratory assessment of medical imaging modalities. Nevertheless, understanding of the connection between these measurements and human observer performance in a broad range of tasks remains far from complete. Focusing...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.597511

    authors: Metz CE,Wagner RF,Doi K,Brown DG,Nishikawa RM,Myers KJ

    更新日期:1995-07-01 00:00:00

  • In-vivo rectal dose measurements with diodes to avoid misadministrations during intracavitary high dose rate brachytherapy for carcinoma of the cervix.

    abstract::Our purpose in this paper is to present an in vivo dosimetry program designed both for measuring the rectal dose and for avoiding misadministrations in gynecological intracavitary implants. A device containing an energy compensated diode was specially designed for these measurements. Our calibration procedure as well ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598598

    authors: Alecu R,Alecu M

    更新日期:1999-05-01 00:00:00

  • Primary dose in photon beams with lateral electron disequilibrium.

    abstract::It is shown that in narrow monoenergetic photon beams under conditions of lateral electron disequilibrium, primary absorbed dose P(r) is a simple function of beam radius r: P(r) = P lambda.(1 - e(-gamma.r)), where P lambda is the primary dose in broad beams for which complete lateral electron equilibrium exists, and g...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596741

    authors: Nizin PS,Chang XS

    更新日期:1991-07-01 00:00:00

  • Potential of high-Z contrast agents in clinical contrast-enhanced computed tomography.

    abstract:PURPOSE:Currently, only iodine- and barium-based contrast media (CM) are used in clinical contrast-enhanced computed tomography (CE-CT). High-Z metals would produce a higher contrast at equal mass density for the x-ray spectra used in clinical CT. Using such materials might allow for significant dose reductions in CE-C...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3658738

    authors: Nowak T,Hupfer M,Brauweiler R,Eisa F,Kalender WA

    更新日期:2011-12-01 00:00:00

  • System considerations in CCD-based x-ray imaging for digital chest radiography and digital mammography.

    abstract::System modeling is used to investigate the effect of various system parameters on the image quality in CCD-based x-ray imaging systems. The systems considered consist of a typical phosphor-based scintillating screen coupled to a CCD through lens or fiberoptic taper. Two applications, chest radiography and mammography,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598072

    authors: Hejazi S,Trauernicht DP

    更新日期:1997-02-01 00:00:00

  • Combined kV and MV imaging for real-time tracking of implanted fiducial markers.

    abstract::In the presence of intrafraction organ motion, target localization uncertainty can greatly hamper the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT). To minimize the adverse dosimetric effect caused by tumor motion, a real-time knowledge of the tumor position is requ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2842072

    authors: Wiersma RD,Mao W,Xing L

    更新日期:2008-04-01 00:00:00

  • Sheet beam x-ray fluorescence computed tomography (XFCT) imaging of gold nanoparticles.

    abstract:PURPOSE:X-ray fluorescence computed tomography (XFCT) experiments have typically used pencil beams for data acquisition, which yielded good quality images of gold nanoparticles (AuNP) but prolonged the imaging time. Here we propose three novel collimator geometries for use with faster sheet beam XFCT data acquisition. ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12893

    authors: Dunning CAS,Bazalova-Carter M

    更新日期:2018-06-01 00:00:00

  • Limitations of two-dimensional treatment planning programs.

    abstract::Some limitations of conventional two-dimensional computer programs used to plan radiation therapy are presented. These include: a lack of involvement in defining the clinical problem; deficiencies in the algorithms for computing dose; failure to compute dose throughout the volume of interest; an inability to handle tr...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595226

    authors: Goitein M

    更新日期:1982-07-01 00:00:00

  • The potential role of positron emission mammography for detection of breast cancer. A phantom study.

    abstract::Positron emission mammography (PEM) is a new, specialized imaging modality utilizing PET radiopharmaceuticals to detect breast cancer. The capabilities and limitations of PEM in detecting breast tumors were investigated with a series of phantom experiments. The PEM imager was mounted on a standard Lorad biopsy table (...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1287439

    authors: Raylman RR,Majewski S,Wojcik R,Weisenberger AG,Kross B,Popov V,Bishop HA

    更新日期:2000-08-01 00:00:00

  • Effect of finite sample size on feature selection and classification: a simulation study.

    abstract:PURPOSE:The small number of samples available for training and testing is often the limiting factor in finding the most effective features and designing an optimal computer-aided diagnosis (CAD) system. Training on a limited set of samples introduces bias and variance in the performance of a CAD system relative to that...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3284974

    authors: Way TW,Sahiner B,Hadjiiski LM,Chan HP

    更新日期:2010-02-01 00:00:00

  • Comparative performance of multiview stereoscopic and mammographic display modalities for breast lesion detection.

    abstract:PURPOSE:Mammography is known to be one of the most difficult radiographic exams to interpret. Mammography has important limitations, including the superposition of normal tissue that can obscure a mass, chance alignment of normal tissue to mimic a true lesion and the inability to derive volumetric information. It has b...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3562901

    authors: Webb LJ,Samei E,Lo JY,Baker JA,Ghate SV,Kim C,Soo MS,Walsh R

    更新日期:2011-04-01 00:00:00

  • MO-D-213CD-04: 4D X-Ray DSA and 4D Fluoroscopy.

    abstract::During the past decade the use of undersampled acquisition and constrained reconstruction have led to significant increases in data acquisition speed, SNR, spatial resolution and temporal resolution in MR imaging. When a separately acquired constraining image is combined with an angiographic time series the traditiona...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735797

    authors: Mistretta C

    更新日期:2012-06-01 00:00:00

  • First study of on-treatment volumetric imaging during respiratory gated VMAT.

    abstract:PURPOSE:To obtain on-treatment volumetric patient anatomy during respiratory gated volumetric modulated arc therapy (VMAT). METHODS:On-board imaging device integrated with Linacs offers a viable tool for obtaining patient anatomy during radiation treatment delivery. In this study, the authors acquired beam-level kV im...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.4794925

    authors: Choi K,Xing L,Koong A,Li R

    更新日期:2013-04-01 00:00:00

  • Computer-aided measurement of liver volumes in CT by means of geodesic active contour segmentation coupled with level-set algorithms.

    abstract:PURPOSE:Computerized liver extraction from hepatic CT images is challenging because the liver often abuts other organs of a similar density. The purpose of this study was to develop a computer-aided measurement of liver volumes in hepatic CT. METHODS:The authors developed a computerized liver extraction scheme based o...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3395579

    authors: Suzuki K,Kohlbrenner R,Epstein ML,Obajuluwa AM,Xu J,Hori M

    更新日期:2010-05-01 00:00:00

  • SU-E-J-63: Feasibility Study of Proton Digital Tomosynthesis in Proton Beam Therapy.

    abstract:PURPOSE:We investigated the feasibility of proton tomosynthesis as daily positioning of patients and compared the results with photon tomosynthesis as an alternative to conventional portal imaging or on-board cone-beam computed tomography. METHODS:Dedicated photon-like proton beam using the passively scattered proton ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734898

    authors: Min B,Kwak J,Lee J,Cho S,Park S,Yoo S,Chung K,Cho S,Lim Y,Shin D,Lee S,Kim J

    更新日期:2012-06-01 00:00:00

  • The report of Task Group 100 of the AAPM: Application of risk analysis methods to radiation therapy quality management.

    abstract::The increasing complexity of modern radiation therapy planning and delivery challenges traditional prescriptive quality management (QM) methods, such as many of those included in guidelines published by organizations such as the AAPM, ASTRO, ACR, ESTRO, and IAEA. These prescriptive guidelines have traditionally focuse...

    journal_title:Medical physics

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1118/1.4947547

    authors: Huq MS,Fraass BA,Dunscombe PB,Gibbons JP Jr,Ibbott GS,Mundt AJ,Mutic S,Palta JR,Rath F,Thomadsen BR,Williamson JF,Yorke ED

    更新日期:2016-07-01 00:00:00

  • SU-E-T-535: Proton Dose Calculations in Homogeneous Media.

    abstract:PURPOSE:To develop a pencil beam dose calculation algorithm for scanned proton beams that improves modeling of scatter events. METHODS:Our pencil beam algorithm (PBA) was developed for calculating dose from monoenergetic, parallel proton beams in homogeneous media. Fermi-Eyges theory was implemented for pencil beam tr...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735624

    authors: Chapman J,Fontenot J,Newhauser W,Hogstrom K

    更新日期:2012-06-01 00:00:00