Intractable diarrhea from cytomegalovirus enterocolitis in an immunocompetent infant.

Abstract:

:Infection with cytomegalovirus (CMV) in infants can be congenital or perinatal. Infected infants may be asymptomatic or present with pneumonia, rash, hepatosplenomegaly, or encephalitis.1 In the presence of an immunodeficiency, severe and sometimes fatal disease may occur. To our knowledge, CMV has not been identified previously as a cause of intractable diarrhea of infancy. We report the case of a 5-week-old immunocompetent infant with intractable diarrhea attributable to CMV-induced enterocolitis. Recognition of this infection and initiation of ganciclovir therapy was associated with a rapid improvement and resolution of the diarrhea.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Fox LM,Gerber MA,Penix L,Ricci A Jr,Hyams JS

doi

10.1542/peds.103.1.e10

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

E10

issue

1

eissn

0031-4005

issn

1098-4275

journal_volume

103

pub_type

杂志文章
  • Gaucher's disease and fatal hepatic fibrosis despite prolonged enzyme replacement therapy.

    abstract::We report on the case of a girl with type 1 Gaucher's disease, treated from age 9 to 15 with high-dose enzyme replacement therapy. This treatment did not avert the development of an extensive mutilating hepatic fibrosis warranting a liver transplantation, which was followed by death. In some cases of Gaucher's disease...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.109.6.1170

    authors: Perel Y,Bioulac-Sage P,Chateil JF,Trillaud H,Carles J,Lamireau T,Guillard JM

    更新日期:2002-06-01 00:00:00

  • Predictors of survival in children born with Down syndrome: a registry-based study.

    abstract:OBJECTIVE:To examine the influence of fetal and maternal characteristics on the survival of children born with Down syndrome. METHODS:We used prospectively collected population-based data on Down syndrome extracted from the UK Northern Congenital Abnormality Survey (NorCAS), January 1, 1985-December 31, 2003, matched ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-3051

    authors: Rankin J,Tennant PW,Bythell M,Pearce MS

    更新日期:2012-06-01 00:00:00

  • Elective high-frequency oscillatory ventilation versus conventional ventilation in preterm infants with pulmonary dysfunction: systematic review and meta-analyses.

    abstract:OBJECTIVES:To systematically review the evidence to determine whether the routine use of high-frequency oscillatory ventilation (HFOV) as compared with conventional ventilation (CV) is beneficial or harmful in preterm infants requiring mechanical ventilation for pulmonary failure principally due to respiratory distress...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.100.5.e6

    authors: Bhuta T,Henderson-Smart DJ

    更新日期:1997-11-01 00:00:00

  • Detection of Mycobacterium tuberculosis in clinical specimens from children using a polymerase chain reaction.

    abstract:OBJECTIVE:We evaluated the usefulness of the polymerase chain reaction (PCR) using the insertion sequence IS6110 as the target for DNA to detect Mycobacterium tuberculosis in clinical specimens from children. STUDY DESIGN:This was a prospective, controlled, blinded study comparing PCR on clinical specimens, mycobacter...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Smith KC,Starke JR,Eisenach K,Ong LT,Denby M

    更新日期:1996-02-01 00:00:00

  • Risk of respiratory illness associated with day-care attendance: a nationwide study.

    abstract::The risk of respiratory and other illnesses in children (age groups: 6 weeks through 17 months, 18 through 35 months, and 36 through 59 months) in various types of day-care facilities was studied. Children considered exposed to day care were those who were enrolled in day care with at least one unrelated child for at ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Hurwitz ES,Gunn WJ,Pinsky PF,Schonberger LB

    更新日期:1991-01-01 00:00:00

  • Pneumococcal meningitis in children: epidemiology, serotypes, and outcomes from 1997-2010 in Utah.

    abstract:BACKGROUND:After licensure of the 7-valent pneumococcal conjugate vaccine (PCV7) in the United States in 2000, the incidence of pediatric pneumococcal meningitis decreased significantly. However, cases continue to occur. It is unknown whether meningitis due to PCV7 and non-PCV7 serotypes causes similar morbidity and mo...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-0621

    authors: Stockmann C,Ampofo K,Byington CL,Filloux F,Hersh AL,Blaschke AJ,Cowan P,Korgenski K,Mason EO,Pavia AT

    更新日期:2013-09-01 00:00:00

  • Chronic Conditions and Health Care Needs of Adolescents Born at 23 to 25 Weeks' Gestation.

    abstract:OBJECTIVE:We examined chronic conditions, functional limitations, and special health care needs in extremely preterm children (EPT; 23-25 weeks' gestation) born between 1992 and 1998 at 2 Swedish tertiary care centers that offered regional and active perinatal care to all live-born EPT infants. METHODS:Of 134 survivin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-2215

    authors: Holsti A,Adamsson M,Hägglöf B,Farooqi A,Serenius F

    更新日期:2017-02-01 00:00:00

  • A case of protein-losing enteropathy caused by intestinal lymphangiectasia in a preterm infant.

    abstract::Intestinal lymphangiectasia is characterized by obstruction of lymph drainage from the small intestine and lacteal dilation that distorts the villus architecture. Lymphatic vessel obstruction and elevated intestinal lymphatic pressure in turn cause lymphatic leakage into the intestinal lumen, thus resulting in malabso...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.2.416

    authors: Salvia G,Cascioli CF,Ciccimarra F,Terrin G,Cucchiara S

    更新日期:2001-02-01 00:00:00

  • Dyssomnias and parasomnias in early childhood.

    abstract:OBJECTIVES:Our aim for this study was to determine the prevalence of dyssomnias and various parasomnias in early childhood and to describe their temporal evolution, gender differences, and correlates. METHODS:This research is part of a longitudinal study of child development. A randomized, 3-level, stratified survey d...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-2132

    authors: Petit D,Touchette E,Tremblay RE,Boivin M,Montplaisir J

    更新日期:2007-05-01 00:00:00

  • Egg Freezing in Childhood and Young Adult Cancer Survivors.

    abstract::Fertility preservation in prepubertal and young adolescent girls scheduled for chemotherapy is a demanding situation. Despite the recent impressive improvements of ovarian cortex cryopreservation, significant limitations persist. The technique remains experimental, it exposes the girl to the risks of surgery and to an...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-0291

    authors: Filippi F,Meazza C,Paffoni A,Raspagliesi F,Terenziani M,Somigliana E

    更新日期:2016-10-01 00:00:00

  • Treatment of plastic bronchitis in a Fontan patient with tissue plasminogen activator: a case report and review of the literature.

    abstract::Plastic bronchitis is a condition in which large, bronchial casts with rubber-like consistency develop in the tracheobronchial tree and cause airway obstruction. We describe a 4-year-old girl who had Fontan physiology and who developed plastic bronchitis and report for the first time the use of aerosolized tissue plas...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.109.4.e67

    authors: Costello JM,Steinhorn D,McColley S,Gerber ME,Kumar SP

    更新日期:2002-04-01 00:00:00

  • Safety of a higher loading dose of phenobarbital in the term newborn.

    abstract::The conventional loading dose of phenobarbital for newborn infants with hypoxic-ischemic seizures, 20 mg/kg, often fails to control convulsive activity. To determine the safety of a higher loading dose and to establish the pharmacokinetic parameters of a higher loading dose, ten severely asphyxiated term newborns were...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Donn SM,Grasela TH,Goldstein GW

    更新日期:1985-06-01 00:00:00

  • Assessment of pediatricians by a regulatory authority.

    abstract:OBJECTIVE:To determine whether it is possible to develop feasible, valid, and reliable multisource feedback data for pediatricians. METHODS:Surveys with 40, 22, 38, and 37 items were developed for assessment of pediatricians by patients, co-workers, medical colleagues, and themselves, respectively, using 5-point scale...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-1403

    authors: Violato C,Lockyer JM,Fidler H

    更新日期:2006-03-01 00:00:00

  • Regulation of arginine vasopressin in enuretic children under fluid restriction.

    abstract:BACKGROUND:Treatment of primary nocturnal enuresis using 1-deamino-8-D-arginine-vasopressin is based on the hypothesis that antidiuretic hormone (arginine vasopressin [AVP]) secretion is insufficient during the night. Persisting doubts about the theoretical background of this treatment and first results pointing to a d...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.103.2.452

    authors: Eggert P,Müller-Schlüter K,Müller D

    更新日期:1999-02-01 00:00:00

  • Media literacy education for elementary school substance use prevention: study of media detective.

    abstract:OBJECTIVES:Media Detective is a 10-lesson elementary school substance use prevention program developed on the basis of the message interpretation processing model designed to increase children's critical thinking skills about media messages and reduce intent to use tobacco and alcohol products. The purpose of this stud...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-0068

    authors: Kupersmidt JB,Scull TM,Austin EW

    更新日期:2010-09-01 00:00:00

  • Cardiac effects of dexamethasone in very low birth weight infants.

    abstract:OBJECTIVE:To characterize the cardiac effects of dexamethasone in very low birth weight infants. DESIGN:Prospective, randomized, placebo-controlled, double-blind trial. Enrolled subjects were randomized to receive either a 42-day tapering course of dexamethasone or a saline placebo. Echocardiographic measurements were...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Bensky AS,Kothadia JM,Covitz W

    更新日期:1996-06-01 00:00:00

  • Epidemiology of inguinal hernia in preterm neonates.

    abstract::We have studied the epidemiology of inguinal hernias in preterm infants. Inguinal hernias occur with increased frequency in infants less than or equal to 32 weeks' gestational age or less than or equal to 1,250 g birth weight. Among infants less than or equal to 32 weeks' gestational age, intrauterine growth retardati...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Peevy KJ,Speed FA,Hoff CJ

    更新日期:1986-02-01 00:00:00

  • Successful treatment of juvenile chronic granulocytic leukemia with marrow transplantation.

    abstract::A 46-month-old boy with juvenile chronic granulocytic leukemia was treated intensively with hydroxyurea, dimethyl myleran, cyclophosphamide, and total body irradiation. He then received a marrow transplant from an HL-A matched brother. Thirty-two months after the transplantation, he is hematologically normal and remai...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sanders JE,Buckner CD,Stewart P,Thomas ED

    更新日期:1979-01-01 00:00:00

  • Alcohol Interventions Among Underage Drinkers in the ED: A Randomized Controlled Trial.

    abstract:OBJECTIVES:This study examined the efficacy of emergency department (ED)-based brief interventions (BIs), delivered by a computer or therapist, with and without a post-ED session, on alcohol consumption and consequences over 12 months. METHODS:Patients (ages 14-20 years) screening positive for risky drinking were rand...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2015-1260

    authors: Cunningham RM,Chermack ST,Ehrlich PF,Carter PM,Booth BM,Blow FC,Barry KL,Walton MA

    更新日期:2015-10-01 00:00:00

  • The emergency physician and the office-based pediatrician: an EMSC team. American Academy of Pediatrics. Committee on Pediatric Emergency Medicine.

    abstract::In a quality and cost-conscious health care environment, the pediatrician and emergency physician must work as a team. This statement clarifies important issues of this relationship, including coordination of patient care, communication between clinicians, provision of continuity care, and responsibility for quality e...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.5.936

    authors:

    更新日期:1998-05-01 00:00:00

  • Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome.

    abstract::A 3.5-year-old healthy boy with 4 days of fever was referred to the emergency department for respiratory distress. The physical examination was remarkable for stupor, tachycardia, tachypnea, and dyspnea. Initial blood tests showed pancytopenia. He rapidly developed torticollis. Computerized tomography of the neck reve...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-2505

    authors: Schmid T,Miskin H,Schlesinger Y,Argaman Z,Kleid D

    更新日期:2005-05-01 00:00:00

  • Intestinal lesions containing coronavirus-like particles in neonatal necrotizing enterocolitis: an ultrastructural analysis.

    abstract::Since the outbreaks of neonatal necrotizing enterocolitis occurring in maternity hospitals of Paris and suburbs in 1979-1980, it has been possible to examine by light and electron microscopy gut specimens from ten newborns with this illness. Coronavirus-like particles, enclosed in intracytoplasmic vesicles of damaged ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rousset S,Moscovici O,Lebon P,Barbet JP,Helardot P,Macé B,Bargy F,Le Tan Vinh,Chany C

    更新日期:1984-02-01 00:00:00

  • Current pediatrician practices in identifying high-risk behaviors of adolescents.

    abstract:OBJECTIVE:In the United States, 15- to 24-year-olds represent approximately 14% of HIV cases diagnosed in 2006 and almost 50% of the 19 million sexually transmitted infections (STIs) reported annually. This survey assessed pediatricians' practices regarding preventive health care screening, provision of reproductive he...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2009-0271

    authors: Henry-Reid LM,O'Connor KG,Klein JD,Cooper E,Flynn P,Futterman DC

    更新日期:2010-04-01 00:00:00

  • Pathogenesis and prevention of necrotizing enterocolitis: a hypothesis based on personal observation and a review of the literature.

    abstract::The hypothesis is, that necrotizing enterocolitis (NEC) of the neonate occurs by the coincidence of two of three pathologic events: (1) intestinal ischemia, (2) colonization by pathogenic bacteria, and (3) excess protein substrate in the intestinal lumen. NEC is more likely to appear following quantitative extremes, i...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Kosloske AM

    更新日期:1984-12-01 00:00:00

  • Clinical disease caused by Klebsiella in 2 unrelated patients with interleukin 12 receptor beta1 deficiency.

    abstract::Patients with interleukin 12 (IL-12)p40 or IL-12 receptor β1 (IL12Rβ1) deficiencies are prone to develop infections caused by mycobacteria and salmonella; other infections have only been rarely observed. In this report we describe 2 unrelated patients with complete autosomal recessive IL12Rβ1 deficiency who suffered f...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-2504

    authors: Pedraza S,Lezana JL,Samarina A,Aldana R,Herrera MT,Boisson-Dupuis S,Bustamante J,Pages P,Casanova JL,Picard C

    更新日期:2010-10-01 00:00:00

  • Impact of the thimerosal controversy on hepatitis B vaccine coverage of infants born to women of unknown hepatitis B surface antigen status in Michigan.

    abstract:OBJECTIVE:Hepatitis B vaccine is recommended for all infants, and the series may be started during the delivery admission. For infants who are born either to women who are positive for hepatitis B surface antigen (HBsAg) or to women whose HBsAg status is unknown, vaccination should be started within 12 hours of birth t...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.111.6.e645

    authors: Biroscak BJ,Fiore AE,Fasano N,Fineis P,Collins MP,Stoltman G

    更新日期:2003-06-01 00:00:00

  • Highly somatizing young adolescents and the risk of depression.

    abstract:OBJECTIVE:To determine if high levels of somatization symptoms in 13- to 16-year-olds from the general population predict risk of major depression and other psychiatric disorders 4 years later. METHOD:Cohort study, using interview and self-report survey data from the 1983 Ontario Child Health Study (OCHS) and 1987 OCH...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.103.6.1203

    authors: Zwaigenbaum L,Szatmari P,Boyle MH,Offord DR

    更新日期:1999-06-01 00:00:00

  • Is office-based counseling about media use, timeouts, and firearm storage effective? Results from a cluster-randomized, controlled trial.

    abstract:OBJECTIVE:The objective of this study was to determine whether patients' families' violence-prevention behaviors would be affected by their primary care practitioner's use of a violence-prevention clinical intervention during the routine well-child examination. METHODS:In this cluster-randomized, controlled trial (200...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2007-2611

    authors: Barkin SL,Finch SA,Ip EH,Scheindlin B,Craig JA,Steffes J,Weiley V,Slora E,Altman D,Wasserman RC

    更新日期:2008-07-01 00:00:00

  • Survival and Impairment of Extremely Premature Infants: A Meta-analysis.

    abstract:CONTEXT:Survival of infants born at the limit of viability varies between high-income countries. OBJECTIVE:To summarize the prognosis of survival and risk of impairment for infants born at 22 + 0/7 weeks' to 27 + 6/7 weeks' gestational age (GA) in high-income countries. DATA SOURCES:We searched 9 databases for cohort...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.2018-0933

    authors: Myrhaug HT,Brurberg KG,Hov L,Markestad T

    更新日期:2019-02-01 00:00:00

  • Invasive Bacterial Infections in Afebrile Infants Diagnosed With Acute Otitis Media.

    abstract:OBJECTIVES:To determine the prevalence of invasive bacterial infections (IBIs) and adverse events in afebrile infants with acute otitis media (AOM). METHODS:We conducted a 33-site cross-sectional study of afebrile infants ≤90 days of age with AOM seen in emergency departments from 2007 to 2017. Eligible infants were i...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-1571

    authors: McLaren SH,Cruz AT,Yen K,Lipshaw MJ,Bergmann KR,Mistry RD,Gutman CK,Ahmad FA,Pruitt CM,Thompson GC,Steimle MD,Zhao X,Schuh AM,Thompson AD,Hanson HR,Ulrich SL,Meltzer JA,Dunnick J,Schmidt SM,Nigrovic LE,Waseem M,

    更新日期:2021-01-01 00:00:00