Abstract:
:Intestinal lymphangiectasia is characterized by obstruction of lymph drainage from the small intestine and lacteal dilation that distorts the villus architecture. Lymphatic vessel obstruction and elevated intestinal lymphatic pressure in turn cause lymphatic leakage into the intestinal lumen, thus resulting in malabsorption and protein-losing enteropathy. Intestinal lymphangiectasia can be congenital or secondary to a disease that blocks intestinal lymph drainage. We describe the first case of intestinal lymphangiectasia in a premature infant. The infant presented with peripheral edema and low serum albumin; high fecal concentration of alpha(1)-antitrypsin documented intestinal protein loss. Endoscopy showed white opaque spots on the duodenal mucosa, which indicates dilated lacteal vessels. Histology confirmed dilated lacteals and also showed villus blunting. A formula containing a high concentration of medium chain triglycerides resulted in a rapid clinical improvement and normalization of biochemical variables. These features should alert neonatologists to the possibility of intestinal lymphangiectasia in newborns with hypoalbuminemia and peripheral edema. The intestinal tract should be examined for enteric protein losses if other causes (ie, malnutrition and protein loss from other sites) are excluded. The diagnosis rests on jejunal biopsy demonstrating dilated lymphatic lacteal vessels.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Salvia G,Cascioli CF,Ciccimarra F,Terrin G,Cucchiara Sdoi
10.1542/peds.107.2.416subject
Has Abstractpub_date
2001-02-01 00:00:00pages
416-7issue
2eissn
0031-4005issn
1098-4275journal_volume
107pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:BACKGROUND AND OBJECTIVES:Effective treatment of childhood obesity remains elusive. Integration of clinical and community systems may achieve effective and sustainable treatment. However, the feasibility and effectiveness of this integrated model are unknown. METHODS:We conducted a randomized clinical trial among chil...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2017-1444
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To investigate the clinical effectiveness of botulinum neurotoxin type A (BoNT) to reduce drooling in children with cerebral palsy (CP). METHODS:A controlled clinical trial was performed in which the results of single-dose BoNT injections in the submandibular glands were compared with treatment with scopolam...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章
doi:10.1542/peds.2003-1104-L
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Adoption and implementation of evidence-based measures for catheter care leads to reductions in central line-associated bloodstream infection (CLABSI) rates in the NICU. The purpose of this study is to evaluate whether this rate reduction is sustainable for at least 1 year and to identify key d...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-2523
更新日期:2015-06-01 00:00:00
abstract::Gastrointestinal food allergies are a spectrum of disorders that result from adverse immune responses to dietary antigens. The named disorders include immediate gastrointestinal hypersensitivity (anaphylaxis), oral allergy syndrome, allergic eosinophilic esophagitis, gastritis, and gastroenterocolitis; dietary protein...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVES:We sought to determine the prevalence of corneal abrasions and possible associations with fingernail length, demographic information, sleeping, and crying among young infants. METHODS:Parents of 1- to 12-week-old infants without symptoms who were presenting for well-child visits completed a brief questionna...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-2023
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To determine whether medically unexplained recurrent abdominal pain (RAP) in childhood predicts abdominal pain, irritable bowel syndrome (IBS), other somatic complaints, and psychiatric symptoms and disorders in young adulthood. METHODS:A sample of 28 young adults evaluated for RAP between the ages of 6 and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.1.e1
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:To assess whether weight-related teasing predicts the development of binge eating, unhealthy weight control behaviors, and frequent dieting among male and female adolescents. METHODS:A prospective study was conducted with an ethnically and socioeconomically diverse sample of 2516 adolescents who completed su...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-1242
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To analyze the costs and benefits of influenza vaccination of healthy school-aged children. DESIGN:The analysis was based on data from the literature. Total costs included direct medical costs for vaccination, physician visits, and treatment as well as indirect costs. Indirect costs were in the form of lost ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.103.6.e73
更新日期:1999-06-01 00:00:00
abstract::Parental requests for gastrostomies, tracheostomies, or assisted ventilation in children with profound disabilities raise ethical concerns about children's interests, parental decision-making, and health care costs. The underlying concern for many relates to the perceived value of these children. Clinicians should mak...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-3608H
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Little is known about duration of protection after the infant primary series of hepatitis B (HB) vaccine in settings of low HB endemicity. This study sought to determine the proportion of adolescents immunized as infants who had protective titers of antibody to hepatitis B surface antigen (anti-HBs) before a...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2013-2940
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Ciliary ultrastructural defects with total lack of dynein arms (DA) cause abnormal mucociliary function leading to the chronic infections observed in primary ciliary dyskinesia. The role of partial ciliary ultrastructural defects, especially those involving the central complex, and their relationship with re...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.5.e86
更新日期:2001-11-01 00:00:00
abstract::Seventy-eight percent of the 384 patients 2 years of age and older who were enrolled in the Cystic Fibrosis Clinic at the Hospital for Sick Children participated in this study of family adjustment to cystic fibrosis. Residence with at least one parent at the time of the survey was a condition for inclusion in the stud...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to use proton magnetic resonance spectroscopy (MRS) as a metabolic assay to describe biochemical changes during the evolution of neuronal injury in infants after shaken baby syndrome (SBS), that explain the disparity between apparent physical injury and the neurological deficit a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.1.4
更新日期:1997-01-01 00:00:00
abstract::In 1984, an outbreak of gastroenteritis occurred at a school with 1,860 students in Brooklyn, NY. In a single-stage cluster sample of 375 students, 129 (34%) had illnesses that met our case definition of vomiting or diarrhea. The mean incubation period was 26 hours, and the mean illness duration was 24 hours. All case...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract::Cases of ophthalmia neonatorum diagnosed at Grady Memorial Hospital 1967-1973 were reviewed. Of 302 cases 43 could be diagnosed as gonococcal, 86 chlamydial, 3 gonococcal and chlamydial, 31 staphylococcal, and 5 chemical. Silver nitrate prophylaxis was routinely employed. Gonococcal cases peaked during the third quart...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-06-01 00:00:00
abstract::In an effort to determine whether iron deficiency, in the absence of anemia (hemoglobin greater than 11.0 g/dL), might produce alterations in behavioral development, four groups of nonanemic infants, 9 to 12 months of age, with varying degrees of iron deficiency were studied. Infants were classified as iron sufficient...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract:OBJECTIVE:To determine clinical characteristics in children with osteogenesis imperfecta (OI) regarding impairment (range of joint motion and muscle strength) and disability (functional skills) in relation to the different types of the disease, and to study the correlation between characteristics of impairment and disa...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.99.2.e3
更新日期:1997-02-01 00:00:00
abstract::In Norway, a national consensus-based guideline used to address thresholds for offering life support at extreme preterm birth was issued in 1998. Since then, therapeutic advances may have changed attitudes and expectations to treatment, both within the medical community and the public, and there are concerns that syst...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2018-0478E
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:Abdominal obesity may be a better predictor than overall obesity for the risk of cardiovascular disease and type 2 diabetes. Waist circumference and waist-height ratio are 2 simple, yet effective, surrogate measures of abdominal obesity. We sought to examine the recent trends in mean waist circumference and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1062
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:In past decades, numerous population- and hospital-based studies have revealed a relationship between migraine or headache and psychopathology in children. OBJECTIVE:To describe and assess all clinical studies on the prevalence and manifestations of psychological functioning and psychiatric comorbidity in c...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2009-3293
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Identity formation and exploration of interpersonal relationships are important tasks that occur during adolescence. Transgender, gender diverse, and gender-nonconforming (TGNC) individuals must face these developmental milestones in the context of their transgender identity. Our aim with this article is to ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-007906
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:To determine the most cost-effective treatment for phimosis. DESIGN:The costs of three treatment strategies for treating phimosis were evaluated using a decision-tree analysis. Three therapeutic approaches were considered: circumcision, preputial plasty (the use of plastic surgical techniques to enlarge the ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.102.4.e43
更新日期:1998-10-01 00:00:00
abstract::Trismus refers to any condition inducing limited mouth opening and may present as a result of acquired or congenital pathology. We present the case of a newborn who presented with severe, congenital trismus due to brainstem dysgenesis. We describe the course of his investigations, and a multidisciplinary approach to t...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2015-4605
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:To compare measures of psychometric assessment and school difficulties in a cohort of extremely low birth weight (ELBW) teenagers and term controls, and to determine whether there is stability in psychometric measures between age 8 and the teen years. STUDY DESIGN:Longitudinal follow-up; geographically defi...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.2.325
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:Each year, children die from heat stroke after being left unattended in motor vehicles. In 2003, the total was 42, up from a national average of 29 for the past 5 years. Previous studies found that on days when ambient temperatures exceeded 86 degrees F, the internal temperatures of the vehicle quickly reache...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-2368
更新日期:2005-07-01 00:00:00
abstract::Two types of waterbeds were developed to impart compensatory vestibular-proprioceptive stimulation to premature infants. Twenty-one infants ranging in gestational age from 27 to 34 weeks and birthweights from 1,050 to 1,920 gm were included in this pilot study. Assignment to experimental and control groups was made by...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1975-09-01 00:00:00
abstract::Commercially available mouse monoclonal antibodies to human IgG subclass (IgG1 to IgG4) were applied to an enzyme-linked immunosorbent assay to measure IgG subclass-specific antibodies to varicella-zoster virus in children naturally infected with varicella-zoster virus and in varicella vaccine recipients. In children ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-12-01 00:00:00
abstract::During and after respiratory tract infections in 29 hospitalized infants, 12 cardiorespiratory measurements were performed on 24-hour recordings of ECG and respiratory activity. These measurements were compared with similar data obtained from 110 age-matched control infants without infection. Respiratory and heart rat...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:Research shows that the development of cardiometabolic disease can begin early in life with risk factors accumulating over time, but less is known about protective pathways to positive health. In this study, we use prospective data to test whether childhood assets predict a greater likelihood of being in opt...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2018-2004
更新日期:2019-03-01 00:00:00
abstract::Informed consent should be seen as an essential part of health care practice; parental permission and childhood assent is an active process that engages patients, both adults and children, in their health care. Pediatric practice is unique in that developmental maturation allows, over time, for increasing inclusion of...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-1485
更新日期:2016-08-01 00:00:00