Successful treatment of juvenile chronic granulocytic leukemia with marrow transplantation.

Abstract:

:A 46-month-old boy with juvenile chronic granulocytic leukemia was treated intensively with hydroxyurea, dimethyl myleran, cyclophosphamide, and total body irradiation. He then received a marrow transplant from an HL-A matched brother. Thirty-two months after the transplantation, he is hematologically normal and remains disease free on no-maintenance therapy. The successful outcome of this case suggests that a bone marrow transplant for any patient with a suitable histocompatible donor should be considered in the treatment of this disease.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Sanders JE,Buckner CD,Stewart P,Thomas ED

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

44-6

issue

1

eissn

0031-4005

issn

1098-4275

journal_volume

63

pub_type

杂志文章
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    pub_type: 杂志文章,评审

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    authors: Metzger RL,Werner DB

    更新日期:1984-06-01 00:00:00

  • Clinical Considerations Related to the Behavioral Manifestations of Child Maltreatment.

    abstract::Children who have suffered early abuse or neglect may later present with significant health and behavior problems that may persist long after the abusive or neglectful environment has been remediated. Neurobiological research suggests that early maltreatment may result in an altered psychological and physiologic respo...

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    authors: Sege RD,Amaya-Jackson L,AMERICAN ACADEMY OF PEDIATRICS Committee on Child Abuse and Neglect, Council on Foster Care, Adoption, and Kinship Care; AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY Committee on Child Maltreatment and Violence; NATION

    更新日期:2017-04-01 00:00:00

  • Down Syndrome and the Risk of Severe RSV Infection: A Meta-analysis.

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    authors: Beckhaus AA,Castro-Rodriguez JA

    更新日期:2018-09-01 00:00:00

  • Effects of environmental exposures on the cardiovascular system: prenatal period through adolescence.

    abstract::Exposures to drugs, chemical and biological agents, therapeutic radiation, and other factors before and after birth can lead to pediatric or adult cardiovascular anomalies. Furthermore, nutritional deficiencies in the perinatal period can cause cardiovascular anomalies. These anomalies may affect heart structure, the ...

    journal_title:Pediatrics

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    authors: Mone SM,Gillman MW,Miller TL,Herman EH,Lipshultz SE

    更新日期:2004-04-01 00:00:00

  • Depressive symptoms in nonresident african american fathers and involvement with their sons.

    abstract:OBJECTIVE:Our objective was to determine whether paternal depressive symptoms were associated with less father involvement among African American fathers not living with their children (ie, nonresident fathers). METHODS:We analyzed survey data for 345 fathers enrolled in a program for nonresident African American fath...

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    doi:10.1542/peds.2009-0718

    authors: Davis RN,Caldwell CH,Clark SJ,Davis MM

    更新日期:2009-12-01 00:00:00

  • High-risk periods for childhood injury among siblings.

    abstract:OBJECTIVE:To determine whether the risk of unintentional injury requiring emergency department (ED) or inpatient care in children is transiently increased over a 90-day period after injury to a sibling. DESIGN:Retrospective cohort. SETTING:King County, Washington. Participants. A total of 41 242 children 0 to 15 year...

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    authors: Johnston BD,Grossman DC,Connell FA,Koepsell TD

    更新日期:2000-03-01 00:00:00

  • Intractable diarrhea from cytomegalovirus enterocolitis in an immunocompetent infant.

    abstract::Infection with cytomegalovirus (CMV) in infants can be congenital or perinatal. Infected infants may be asymptomatic or present with pneumonia, rash, hepatosplenomegaly, or encephalitis.1 In the presence of an immunodeficiency, severe and sometimes fatal disease may occur. To our knowledge, CMV has not been identified...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.103.1.e10

    authors: Fox LM,Gerber MA,Penix L,Ricci A Jr,Hyams JS

    更新日期:1999-01-01 00:00:00

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-3400

    authors: Jyonouchi S,McDonald-McGinn DM,Bale S,Zackai EH,Sullivan KE

    更新日期:2009-05-01 00:00:00

  • Protection Versus Progress: The Challenge of Research on Cannabis Use During Pregnancy.

    abstract::A central tension in pediatric research ethics arises from our desire to protect children from harm while also allowing progress toward discoveries that could improve child health. A prime example of this tension is research on a controversial yet increasingly common practice: the use of cannabis by women to treat nau...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-0818R

    authors: MacDuffie KE,Kleinhans NM,Stout K,Wilfond BS

    更新日期:2020-08-01 00:00:00

  • Treatment outcomes of overweight children and parents in the medical home.

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    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

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    authors: Quattrin T,Roemmich JN,Paluch R,Yu J,Epstein LH,Ecker MA

    更新日期:2014-08-01 00:00:00

  • Early developmental outcomes of children with congenital HHV-6 infection.

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-0886

    authors: Caserta MT,Hall CB,Canfield RL,Davidson P,Lofthus G,Schnabel K,Carnahan J,Shelley L,Wang H

    更新日期:2014-12-01 00:00:00

  • Airway clearance in Duchenne muscular dystrophy.

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    journal_title:Pediatrics

    pub_type: 杂志文章,评审

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    authors: Kravitz RM

    更新日期:2009-05-01 00:00:00

  • Which children benefit the most from early intervention?

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    pub_type: 杂志文章

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    authors: Ramey CT,Ramey SL

    更新日期:1994-12-01 00:00:00

  • Determination of cerebral death in the pediatric intensive care unit.

    abstract::The clinical course, laboratory data, outcome, and autopsy findings in 61 pediatric patients with suspected brain death were reviewed. In 58% of patients, the initial EEG was isoelectric, and cerebral blood flow was absent. In six of nine children, the initial EEG, which showed activity, became isoelectric by 72 hours...

    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Drake B,Ashwal S,Schneider S

    更新日期:1986-07-01 00:00:00

  • Assessment of antifungal therapy in an 800-gram infant with candidal arthritis and osteomyelitis.

    abstract::A 720-g premature newborn developed disseminated candidiasis during treatment with systemic antibiotics and total parenteral nutrition through an umbilical arterial catheter. Clinical features were typical for candidal skeletal infection at this age and included warmth and fusiform swelling of the lower extremities to...

    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Ward RM,Sattler FR,Dalton AS Jr

    更新日期:1983-08-01 00:00:00

  • Enterovirus 71 infection: report of an outbreak with two cases of paralysis and a review of the literature.

    abstract::Enterovirus 71 (E-71) infection was first reported in 19745 in the United States; subsequent outbreaks were reported in worldwide distribution. In the summer of 1977, we identified 12 patients, mostly children, with E-71 infection. The striking feature of this outbreak is the occurrence of two cases with polio-like pa...

    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Chonmaitree T,Menegus MA,Schervish-Swierkosz EM,Schwalenstocker E

    更新日期:1981-04-01 00:00:00

  • Child passenger deaths involving alcohol-impaired drivers.

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    pub_type: 杂志文章

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    authors: Quinlan K,Shults RA,Rudd RA

    更新日期:2014-06-01 00:00:00

  • Fluoride supplement prescribing and dental referral patterns among academic pediatricians.

    abstract:OBJECTIVE:To determine how well the current fluoride supplementation schedule was known by academic pediatricians and to examine the fluoride supplement prescribing and dental referral practices among primary care faculty pediatricians at four medical centers. SETTING:Four university medical centers in North Carolina....

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.1.e6

    authors: Roberts MW,Keels MA,Sharp MC,Lewis JL Jr

    更新日期:1998-01-01 00:00:00

  • Exemplar pediatric collaborative improvement networks: achieving results.

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    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Billett AL,Colletti RB,Mandel KE,Miller M,Muething SE,Sharek PJ,Lannon CM

    更新日期:2013-06-01 00:00:00

  • Evaluation of psychopathological conditions in children with heavy prenatal alcohol exposure.

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    journal_title:Pediatrics

    pub_type: 杂志文章

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    authors: Fryer SL,McGee CL,Matt GE,Riley EP,Mattson SN

    更新日期:2007-03-01 00:00:00

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ungerer JA,Horgan B,Chaitow J,Champion GD

    更新日期:1988-02-01 00:00:00

  • Risk for PHACE syndrome in infants with large facial hemangiomas.

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    authors: Haggstrom AN,Garzon MC,Baselga E,Chamlin SL,Frieden IJ,Holland K,Maguiness S,Mancini AJ,McCuaig C,Metry DW,Morel K,Powell J,Perkins SM,Siegel D,Drolet BA

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  • DMSA scan for revealing vesicoureteral reflux in young children with urinary tract infection.

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

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    更新日期:1978-10-01 00:00:00

  • Missed opportunities for childhood vaccinations in office practices and the effect on vaccination status.

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Szilagyi PG,Rodewald LE,Humiston SG,Raubertas RF,Cove LA,Doane CB,Lind PH,Tobin MS,Roghmann KJ,Hall CB

    更新日期:1993-01-01 00:00:00

  • Evaluation of New York State's Child Health Plus: children who have asthma.

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    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Szilagyi PG,Holl JL,Rodewald LE,Yoos L,Zwanziger J,Shone LP,Mukamel DB,Trafton S,Dick AW,Raubertas RF

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  • Duration of poverty and child health in the Quebec Longitudinal Study of Child Development: longitudinal analysis of a birth cohort.

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