Highly somatizing young adolescents and the risk of depression.

Abstract:

OBJECTIVE:To determine if high levels of somatization symptoms in 13- to 16-year-olds from the general population predict risk of major depression and other psychiatric disorders 4 years later. METHOD:Cohort study, using interview and self-report survey data from the 1983 Ontario Child Health Study (OCHS) and 1987 OCHS Follow-up. The study population included 1015 13- to 16-year-olds from the general community within Ontario. Baseline levels of somatization and emotional disorder were measured by the Survey Diagnostic Instrument, a checklist based on DSM-III criteria. Data were also collected for a range of sociodemographic factors, as well as the presence of chronic health problems. Major depression, anxiety disorders, and substance abuse and dependency at follow-up were measured using a self-administered questionnaire derived from the Diagnostic Interview Schedule. Bivariate and multiple logistic regression techniques were used to assess the relationship between high levels of somatization symptoms (>90th percentile) and later emotional morbidity, with adjustment for potential confounding factors, including gender and baseline disorders. RESULTS:Highly somatizing adolescents are at increased risk of major depression 4 years later, an association that is not explained by detectable emotional disorder at baseline or gender differences between groups. There is an important interaction between somatization and emotional disorder in predicting risk of major depression. It is primarily the group of 13- to 16-year-olds not recognized as being emotionally disordered at the initial OCHS survey in which somatization symptoms increased risk of later depression. The young teen with high levels of somatic complaints had as much risk of later depression as his/her peer with more typical symptoms of emotional disorder. Highly somatizing adolescents were also more likely to describe panic attacks at 4-year follow-up. There was no increased risk of substance abuse/dependency in the highly somatizing group or in generalized anxiety. CONCLUSIONS:High levels of somatic symptoms identified in young adolescents in the community represent a significant risk factor for major depression 4 years later, particularly in those individuals who do not present with more typical symptoms of emotional disorder. To detect the emergence of this serious emotional morbidity, adequate follow-up and continuity of care for these challenging patients are needed.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Zwaigenbaum L,Szatmari P,Boyle MH,Offord DR

doi

10.1542/peds.103.6.1203

subject

Has Abstract

pub_date

1999-06-01 00:00:00

pages

1203-9

issue

6 Pt 1

eissn

0031-4005

issn

1098-4275

journal_volume

103

pub_type

杂志文章
  • Socioeconomic, family, and pediatric practice factors that affect level of asthma control.

    abstract:BACKGROUND:Multiple issues play a role in the effective control of childhood asthma. OBJECTIVE:To identify factors related to the level of asthma control in children receiving asthma care from community pediatricians. PATIENTS AND METHODS:Data for 362 children participating in an intervention study to reduce asthma m...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0504

    authors: Bloomberg GR,Banister C,Sterkel R,Epstein J,Bruns J,Swerczek L,Wells S,Yan Y,Garbutt JM

    更新日期:2009-03-01 00:00:00

  • Temperament and regulation of emotion in the first years of life.

    abstract::Temperament is the tendency to express particular emotions with a certain intensity that is unique to each individual child. Although temperament seems to be biologically based, learning to regulate emotional expressions depends on caregiver input and socialization. Part of this process involves forming a trusting rel...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Fox NA

    更新日期:1998-11-01 00:00:00

  • VAD as bridge to recovery in anthracycline-induced cardiomyopathy and HHV6 myocarditis.

    abstract::This report describes an 8-year-old child with acute anthracycline-induced cardiomyopathy triggered by human herpesvirus 6 and the subsequent implantation of an intracorporeal continuous-flow left ventricular assist device (LVAD) and the process to discharge the child from the hospital. After barely 3 months on mechan...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-2272

    authors: Cavigelli-Brunner A,Schweiger M,Knirsch W,Stiasny B,Klingel K,Kretschmar O,Hübler M

    更新日期:2014-09-01 00:00:00

  • The clinical, biochemical, and familial presentation of type V hyperlipoproteinemia in childhood.

    abstract::Primary type V hyperlipoproteinemia was identified in two preadolescent children. The propositus (kindred N) was a 10-year-old girl with severely creamy plasma, lipemia retinalis, hypertriglyceridemia (triglyceridelevel, 6,800 mg/100 ml), and ypercholesterolemia (cholesterol level, 490 mg/100 ml). Her parents and an 8...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Kwiterovich PO Jr,Farah JR,Brown WV,Bachorik PS,Baylin SB,Neill CA

    更新日期:1977-04-01 00:00:00

  • Discrepancies between direct and indirect blood pressure measurements using various recommendations for arm cuff selection.

    abstract:OBJECTIVE:The current recommendation for choosing an appropriate size cuff for measuring blood pressure (BP) is a bladder width to equal 40% of the upper arm circumference (UAC). However, most physicians use the older two-thirds or three-fourths upper arm length (UAL) recommendations to choose a cuff. The aim of this s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.110.5.920

    authors: Clark JA,Lieh-Lai MW,Sarnaik A,Mattoo TK

    更新日期:2002-11-01 00:00:00

  • Early puberty and adolescent pregnancy: the influence of alcohol use.

    abstract:OBJECTIVE:Early pubertal timing predicts deleterious outcomes for young girls, including substance use, risky sexual behavior, and pregnancy. In turn, adolescent pregnancy predicts long-term negative consequences such as reduced educational attainment and income-earning potential. Despite evidence of the direct links b...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-0542

    authors: Deardorff J,Gonzales NA,Christopher FS,Roosa MW,Millsap RE

    更新日期:2005-12-01 00:00:00

  • Maternal psychological reaction to newborn genetic screening for type 1 diabetes.

    abstract:OBJECTIVE:The purpose of this work was to describe levels of maternal anxiety, depressive symptoms, and perceptions of infant vulnerability associated with newborn genetic screening for susceptibility to type 1 diabetes. PATIENTS AND METHODS:Mothers of infants tested at birth for genetic susceptibility to type 1 diabe...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2006-1381

    authors: Kerruish NJ,Campbell-Stokes PL,Gray A,Merriman TR,Robertson SP,Taylor BJ

    更新日期:2007-08-01 00:00:00

  • Diagnosis and treatment of acute otitis media: an assessment.

    abstract:OBJECTIVE:To assess compliance with the Centers for Disease Control and Prevention (CDC) evidence-based guidelines for the judicious use of antimicrobials in children with acute otitis media (AOM). METHODS:Compliance with CDC's recommended diagnostic criteria and antimicrobial treatments for management of AOM was asse...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.1.143

    authors: Garbutt J,Jeffe DB,Shackelford P

    更新日期:2003-07-01 00:00:00

  • Low-dose atomoxetine for maintenance treatment of attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:Data from acute studies of atomoxetine in patients with attention-deficit/hyperactivity disorder suggest that a dose of approximately 1.2 mg/kg per day is required to attain a maximal symptom response. However, lower doses could be effective during maintenance treatment, which would reduce drug exposure and p...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-2999

    authors: Newcorn JH,Michelson D,Kratochvil CJ,Allen AJ,Ruff DD,Moore RJ,Atomoxetine Low-dose Study Group.

    更新日期:2006-12-01 00:00:00

  • Recommendations for Prevention and Control of Influenza in Children, 2015-2016.

    abstract::The purpose of this statement is to update recommendations for routine use of seasonal influenza vaccine and antiviral medications for the prevention and treatment of influenza in children. The American Academy of Pediatrics recommends annual seasonal influenza immunization for all people 6 months and older, including...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2015-2920

    authors: Committee on Infectious Diseases, American Academy of Pediatrics.

    更新日期:2015-10-01 00:00:00

  • Parent-Adolescent Agreement About Adolescents' Suicidal Thoughts.

    abstract::: media-1vid110.1542/5972300121001PEDS-VA_2018-1771Video Abstract OBJECTIVES: To examine agreement between parent and adolescent reports of adolescents' suicidal thoughts and explore demographic and clinical factors associated with agreement in a large community sample. METHODS:Participants included 5137 adolescents ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2018-1771

    authors: Jones JD,Boyd RC,Calkins ME,Ahmed A,Moore TM,Barzilay R,Benton TD,Gur RE

    更新日期:2019-02-01 00:00:00

  • Emergency Department and Hospital Use Among Adolescents With Justice System Involvement.

    abstract:OBJECTIVES:Adolescents with justice system involvement have high rates of physical and behavioral health disorders and are potentially high users of costly health care services. We examined emergency department (ED) and hospital use among a national sample of adolescents with various levels of justice involvement. MET...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-1144

    authors: Winkelman TNA,Genao I,Wildeman C,Wang EA

    更新日期:2017-11-01 00:00:00

  • Decreasing PICU catheter-associated bloodstream infections: NACHRI's quality transformation efforts.

    abstract:OBJECTIVE:Despite the magnitude of the problem of catheter-associated bloodstream infections (CA-BSIs) in children, relatively little research has been performed to identify effective strategies to reduce these complications. In this study, we aimed to develop and evaluate effective catheter-care practices to reduce pe...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2009-1382

    authors: Miller MR,Griswold M,Harris JM 2nd,Yenokyan G,Huskins WC,Moss M,Rice TB,Ridling D,Campbell D,Margolis P,Muething S,Brilli RJ

    更新日期:2010-02-01 00:00:00

  • Cumulative prevalence of arrest from ages 8 to 23 in a national sample.

    abstract:OBJECTIVE:To estimate the cumulative proportion of youth who self-report having been arrested or taken into custody for illegal or delinquent offenses (excluding arrests for minor traffic violations) from ages 8 to 23 years. METHODS:Self-reported arrest history data (excluding arrests for minor traffic violations) fro...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3710

    authors: Brame R,Turner MG,Paternoster R,Bushway SD

    更新日期:2012-01-01 00:00:00

  • Changing Trends in Asthma Prevalence Among Children.

    abstract:BACKGROUND:Childhood asthma prevalence doubled from 1980 to 1995 and then increased more slowly from 2001 to 2010. During this second period, racial disparities increased. More recent trends remain to be described. METHODS:We analyzed current asthma prevalence using 2001-2013 National Health Interview Survey data for ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-2354

    authors: Akinbami LJ,Simon AE,Rossen LM

    更新日期:2016-01-01 00:00:00

  • Creation and development of the public service orphan drug Human Botulism Immune Globulin.

    abstract::The public service orphan drug Human Botulism Immune Globulin for the treatment of infant botulism would not have come into existence without the federal Orphan Drug Act and the funding mechanism that it provided to conduct pivotal clinical trials. Nonetheless, creating, developing, and achieving licensure of Human Bo...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2006-0646

    authors: Arnon SS

    更新日期:2007-04-01 00:00:00

  • Psychosocial functioning in children and young adults with juvenile arthritis.

    abstract::A questionnaire survey of 363 children and young adults with juvenile arthritis was conducted to assess the relations among disease severity, psychosocial functioning, and adjustment in three age groups--primary school, high school, and young adult. Parents were surveyed separately to determine which characteristics o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ungerer JA,Horgan B,Chaitow J,Champion GD

    更新日期:1988-02-01 00:00:00

  • Effect of intramuscular vitamin E on mortality and intracranial hemorrhage in neonates of 1000 grams or less.

    abstract::A randomized, double-blind study to determine the effect of intramuscular vitamin E on mortality and intracranial hemorrhage (ICH) was performed. One hundred forty-nine neonates with birth weights less than or equal to 1000 g and less than or equal to 24 hours of age were grouped by weight (501 to 750 g and 751 to 100...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Fish WH,Cohen M,Franzek D,Williams JM,Lemons JA

    更新日期:1990-04-01 00:00:00

  • Selective intrapartum prophylaxis for group B streptococcus colonization: management and outcome of newborns.

    abstract:OBJECTIVE:Intrapartum antibiotic prophylaxis (IAP) in mothers with group B streptococcus (GBS) colonization presents difficult neonatal management decisions. IAP was instituted in response to an increased incidence of early-onset GBS sepsis (EOGBSS), and a study was conducted to evaluate the outcome of these newborns. ...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Pylipow M,Gaddis M,Kinney JS

    更新日期:1994-04-01 00:00:00

  • Body image and dieting behavior in cystic fibrosis.

    abstract:OBJECTIVE:To examine the relationship between pulmonary function, nutritional status, body image, and eating attitudes in children with cystic fibrosis (CF) compared with healthy controls. METHOD:Seventy-six children with CF (39 girls) and 153 healthy control children (82 girls) were recruited. All children were betwe...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.6.e92

    authors: Truby H,Paxton AS

    更新日期:2001-06-01 00:00:00

  • High technology for handicapped children: a pediatrician's viewpoint.

    abstract::Children with various types of disabilities are beginning to benefit from the extensive developments in the field of electronic and microcomputer technology that have occurred in recent years. There exists now many devices that can assist children with physical or communication handicaps, learning difficulties, or sen...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Desch LW

    更新日期:1986-01-01 00:00:00

  • Management of congenital adrenal hyperplasia using serum dehydroepiandrosterone sulfate and 17-hydroxyprogesterone concentrations.

    abstract::Simultaneous serum concentrations of dehydroepiandrosterone sulfate (DHEA-S) and 17-hydroxyprogesterone (17-OHP) were compared with urinary 17-ketosteroid (17-KS) and pregnanetriol (PT) excretion during therapy in 18 prepubertal patients with the 21-hydroxylase deficiency form of congenital adrenal hyperplasia (CAH). ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Golden MP,Lippe BM,Kaplan SA,Lavin N,Slavin J

    更新日期:1978-06-01 00:00:00

  • Immunologic defects in patients with refractory sinusitis.

    abstract::Sixty-one patients with chronic sinusitis who were referred for an allergy evaluation were evaluated for immunologic competence including assessment of quantitative serum immunoglobulin levels, IgG subclass levels, and response to pneumococcal and Haemophilus influenzae vaccines. In addition to chronic sinus disease, ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Shapiro GG,Virant FS,Furukawa CT,Pierson WE,Bierman CW

    更新日期:1991-03-01 00:00:00

  • Secondhand smoke exposure and neurobehavioral disorders among children in the United States.

    abstract:OBJECTIVES:The association between parent-reported postnatal secondhand tobacco smoke exposure in the home and neurobehavioral disorders (attention-deficit/hyperactivity disorder, learning disabilities, and conduct disorders) among children younger than 12 years in the United States was examined using the 2007 National...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-0023

    authors: Kabir Z,Connolly GN,Alpert HR

    更新日期:2011-08-01 00:00:00

  • Chylothorax in infants and children.

    abstract::Chylothorax, the accumulation of chyle in the pleural space, is a relatively rare cause of pleural effusion in children. It can cause significant respiratory morbidity, as well as lead to malnutrition and immunodeficiency. Thus, a chylothorax requires timely diagnosis and treatment. This review will first discuss the ...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2013-2072

    authors: Tutor JD

    更新日期:2014-04-01 00:00:00

  • Erythropoietin concentrations and neurodevelopmental outcome in preterm infants.

    abstract:OBJECTIVE:Erythropoietin therapy is effective in decreasing transfusions to varying degrees in preterm infants. Recent animal studies using erythropoietin doses to achieve serum concentrations > 1000 mU/mL report neuroprotective effects. We evaluated the relationship between erythropoietin concentrations and neurodevel...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-3186

    authors: Bierer R,Peceny MC,Hartenberger CH,Ohls RK

    更新日期:2006-09-01 00:00:00

  • Timing of Complementary Feeding Introduction and Adiposity Throughout Childhood.

    abstract:OBJECTIVES:To examine associations of the timing of complementary feeding (CF) introduction with adiposity throughout childhood. METHODS:We studied 1013 children from Project Viva. Our exposure was CF introduction, categorized as <4 months (19%), 4 to <6 months (68%; reference group), and ≥6 months of age (14%). Our o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-1320

    authors: Gingras V,Aris IM,Rifas-Shiman SL,Switkowski KM,Oken E,Hivert MF

    更新日期:2019-12-01 00:00:00

  • The National Children's Study: Recruitment Outcomes Using the Provider-Based Recruitment Approach.

    abstract:OBJECTIVE:In 2009, the National Children's Study (NCS) Vanguard Study tested the feasibility of household-based recruitment and participant enrollment using a birth-rate probability sample. In 2010, the NCS Program Office launched 3 additional recruitment approaches. We tested whether provider-based recruitment could i...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-4410E

    authors: Hale DE,Wyatt SB,Buka S,Cherry D,Cislo KK,Dudley DJ,McElfish PA,Norman GS,Reynolds SA,Siega-Riz AM,Wadlinger S,Walker CK,Robbins JM

    更新日期:2016-06-01 00:00:00

  • Is a "wage-payment" model for research participation appropriate for children?

    abstract:OBJECTIVE:Our goal was to evaluate the applicability of a "wage-payment" model to inducements for children to participate in research. SUBJECTS AND METHODS:We interviewed 42 children and adolescents between the ages of 4 and 16 years who had diabetes, asthma, seizures, or no chronic medical condition. The interview ex...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1813

    authors: Bagley SJ,Reynolds WW,Nelson RM

    更新日期:2007-01-01 00:00:00

  • Effects of therapeutic irradiation delivered in early childhood upon subsequent lung function.

    abstract::To determine the long-term effects of therapeutic pulmonary irradiation and treatment with actinomycin D during a period of lung growth, 12 patients treated for Wilms' tumor metastatic to the lung and 8 patients treated for Wilms' tumor with no evidence of pulmonary metastases were studied 7 to 14 years after their in...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Wohl ME,Griscom NT,Traggis DG,Jaffe N

    更新日期:1975-04-01 00:00:00