Creation and development of the public service orphan drug Human Botulism Immune Globulin.

abstract：INTRODUCTION:Persistent patent ductus arteriosus (PDA) often produces hemodynamic and respiratory derangement necessitating use of inotropic drugs and escalating ventilatory support in premature infants. When medical therapy fails, surgical ligation is indicated. Because of the risks of transferring unstable neonates t...

journal_title：Pediatrics

authors： Gould DS,Montenegro LM,Gaynor JW,Lacy SP,Ittenbach R,Stephens P,Steven JM,Spray TL,Nicolson SC

更新日期：2003-12-01 00:00:00

abstract：:This policy statement, which recognizes the large changes in immigrant status since publication of the 2005 statement "Providing Care for Immigrant, Homeless, and Migrant Children," focuses on strategies to support the health of immigrant children, infants, adolescents, and young adults. Homeless children will be addr...

journal_title：Pediatrics

authors： Council on Community Pediatrics.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:A new once-a-day methylphenidate (MPH) formulation, Concerta (methylphenidate HCl) extended-release tablets (OROS MPH), has been developed. This study was conducted to determine the safety and efficacy of OROS MPH in a multicenter, randomized, clinical trial. METHODS:Children with attention-deficit/hyperacti...

journal_title：Pediatrics

authors： Wolraich ML,Greenhill LL,Pelham W,Swanson J,Wilens T,Palumbo D,Atkins M,McBurnett K,Bukstein O,August G

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:We investigated the relationship between prenatal exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment of Mexican farm-workers' children in California. METHODS:Participants from the Center for the Health Assessment of Mothers and Children of Salina...

journal_title：Pediatrics

authors： Eskenazi B,Marks AR,Bradman A,Fenster L,Johnson C,Barr DB,Jewell NP

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of selective nontreatment of extremely premature, critically ill, or malformed infants among all infant deaths in a level III intensive care nursery (ICN) and to determine the reasons documented by neonatologists for their decisions to withdraw or withhold life support. METHODS:Thi...

journal_title：Pediatrics

authors： Wall SN,Partridge JC

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of a "walking school bus" program on children's rates of active commuting to school and physical activity. METHODS:We conducted a pilot cluster randomized controlled trial among 4th-graders from 8 schools in Houston, Texas (N = 149). Random allocation to treatment or control conditions...

journal_title：Pediatrics

authors： Mendoza JA,Watson K,Baranowski T,Nicklas TA,Uscanga DK,Hanfling MJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Adults born preterm score lower on performance-based tests of executive functioning (EF) than their term-born peers. These test scores do not necessarily translate to application of these skills in an everyday environment. The objective of the study was to test differences between very low birt...

journal_title：Pediatrics

authors： Heinonen K,Pesonen AK,Lahti J,Pyhälä R,Strang-Karlsson S,Hovi P,Järvenpää AL,Eriksson JG,Andersson S,Kajantie E,Raikkonen K

更新日期：2013-01-01 00:00:00

abstract：:In the last 20 years, two thirds of all new vaccines provided worldwide have been produced by a US network of independent industrial, governmental, and academic partners engaged in vaccine research and development. Vaccines are complex products and the science of vaccinology is difficult. To achieve the full promise o...

journal_title：Pediatrics

authors：

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:For preventing nosocomial influenza infections and to facilitate prompt antiviral therapy, an accessible, rapid diagnostic method for influenzavirus is needed. We evaluated the performance of a lateral-flow immunoassay (QuickVue Influenza Test) completed at the bedside of hospitalized children during the infl...

journal_title：Pediatrics

authors： Poehling KA,Griffin MR,Dittus RS,Tang YW,Holland K,Li H,Edwards KM

更新日期：2002-07-01 00:00:00

abstract：:Alcohol use continues to be problematic for youth and young adults in the United States. Understanding of neurobiology and neuroplasticity continues to highlight the potential adverse impact of underage drinking on the developing brain. This policy statement provides the position of the American Academy of Pediatrics ...

journal_title：Pediatrics

authors： Quigley J,COMMITTEE ON SUBSTANCE USE AND PREVENTION.

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To test the effect of nonnutritive sucking (NNS), music therapy (MT), and combined NNS and MT (NNS + MT), versus no intervention, on heart rate, transcutaneous oxygen (TcPaO(2)) levels, and pain behavior of neonates in intensive care units having blood taken by a heel-stick procedure. METHODOLOGY:A within-su...

journal_title：Pediatrics

authors： Bo LK,Callaghan P

更新日期：2000-04-01 00:00:00

abstract：:Between 1993 and 2000, 30 infants were hospitalized with acute pulmonary hemorrhage at Rainbow Babies and Children's Hospital in Cleveland. Most infants presented with severe pulmonary symptoms requiring intensive support, but a few infants had less severe hemorrhage. Three quarters of the patients required ventilator...

journal_title：Pediatrics

authors： Dearborn DG,Smith PG,Dahms BB,Allan TM,Sorenson WG,Montana E,Etzel RA

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:Our goal was to evaluate the applicability of a "wage-payment" model to inducements for children to participate in research. SUBJECTS AND METHODS:We interviewed 42 children and adolescents between the ages of 4 and 16 years who had diabetes, asthma, seizures, or no chronic medical condition. The interview ex...

journal_title：Pediatrics

authors： Bagley SJ,Reynolds WW,Nelson RM

更新日期：2007-01-01 00:00:00

abstract：:Parental requests for gastrostomies, tracheostomies, or assisted ventilation in children with profound disabilities raise ethical concerns about children's interests, parental decision-making, and health care costs. The underlying concern for many relates to the perceived value of these children. Clinicians should mak...

journal_title：Pediatrics

authors： Wilfond BS

更新日期：2014-02-01 00:00:00

abstract：:Recently, a 7-month-old, terminally ill Gypsy infant was admitted to a pediatric intensive care unit. Treating this child and her extended family was a challenging experience during which numerous culture-related problems were encountered. The Gypsy approach to acute medical care consisted of the presence of a large e...

journal_title：Pediatrics

authors： Wetzel RC,Dean JM,Rogers MC

更新日期：1983-11-01 00:00:00

abstract：:To define predictive or contributory risk factors for pancreatitis in human immunodeficiency virus-infected children receiving dideoxyinosine (ddI), the authors evaluated 95 children, 3 months to 18 years of age, who had received ddI at 60 to 540 mg/m2 per day for a mean of 56 weeks. Pancreatitis developed in 7 patien...

journal_title：Pediatrics

authors： Butler KM,Venzon D,Henry N,Husson RN,Mueller BU,Balis FM,Jacobsen F,Lewis LL,Pizzo PA

更新日期：1993-04-01 00:00:00

abstract：:Postnatal ductal closure is stimulated by rising oxygen tension and withdrawal of vasodilatory mediators (prostaglandins, nitric oxide, adenosine) and by vasoconstrictors (endothelin-1, catecholamines, contractile prostanoids), ion channels, calcium flux, platelets, morphologic maturity, and a favorable genetic predis...

journal_title：Pediatrics

authors： Hamrick SEG,Sallmon H,Rose AT,Porras D,Shelton EL,Reese J,Hansmann G

更新日期：2020-11-01 00:00:00

abstract：:The interval from the beginning of the Q wave to the origin of the T wave (Q-oTc interval) and total and ionized serum calcium levels were measured in 27 full-term and 77 premature infants. The correlation between Q-oTc and total and ionized calcium levels was significant in both full-term and normal premature infants...

journal_title：Pediatrics

authors： Giacoia GP,Wagner HR

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:The Reach Out and Read (ROR) program promotes early literacy as part of pediatric primary care through the distribution of children's books and anticipatory guidance during early childhood. OBJECTIVES:To improve the rates of age-appropriate book-giving during well-child care and the delivery of ROR-recommen...

journal_title：Pediatrics

authors： Khandekar AA,Augustyn M,Sanders L,Zuckerman B

更新日期：2011-04-01 00:00:00

abstract：:During and after respiratory tract infections in 29 hospitalized infants, 12 cardiorespiratory measurements were performed on 24-hour recordings of ECG and respiratory activity. These measurements were compared with similar data obtained from 110 age-matched control infants without infection. Respiratory and heart rat...

journal_title：Pediatrics

authors： Southall DP,Stebbens VA,Alexander JR,Cardle CM,Cogswell JJ

更新日期：1986-07-01 00:00:00

abstract：:Epidemiologic and clinical features of Kawasaki disease in 106 patients seen between 1980 and 1986 at The New York Hospital in midtown Manhattan were compared with those in large series from the United States, Canada, and Japan. Dissimilarities in our Kawasaki disease experience included ethnic heterogeneity of our pa...

journal_title：Pediatrics

authors： Ichida F,Fatica NS,O'Loughlin JE,Klein AA,Snyder MS,Levin AR,Ehlers KH,Lesser ML,Engle MA

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the ability of acute dimercaptosuccinic acid (DMSA) scintigraphy for revealing vesicoureteral reflux (VUR) in young children after a first febrile urinary tract infection (UTI). METHODS:Children aged

journal_title：Pediatrics

authors： Fouzas S,Krikelli E,Vassilakos P,Gkentzi D,Papanastasiou DA,Salakos C

更新日期：2010-09-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:Primary generalized tonic-clonic seizures are relatively more common among children than among adults. Primary generalized tonic-clonic seizures are associated with increased risk of injury and death. Therefore, effective control of primary generalized tonic-clonic seizures is necessary to reduce ...

journal_title：Pediatrics

authors： Trevathan E,Kerls SP,Hammer AE,Vuong A,Messenheimer JA

更新日期：2006-08-01 00:00:00

abstract：:Gastrointestinal food allergies are a spectrum of disorders that result from adverse immune responses to dietary antigens. The named disorders include immediate gastrointestinal hypersensitivity (anaphylaxis), oral allergy syndrome, allergic eosinophilic esophagitis, gastritis, and gastroenterocolitis; dietary protein...

journal_title：Pediatrics

authors： Sicherer SH

更新日期：2003-06-01 00:00:00

abstract：:The Metropolitan Atlanta Developmental Disabilities Study is the first US, population-based epidemiologic study of the prevalence of mental retardation, cerebral palsy, hearing impairment, and visual impairment among school-age children. The study population consisted of children who were 10 years of age between 1985 ...

journal_title：Pediatrics

authors： Yeargin-Allsopp M,Murphy CC,Oakley GP,Sikes RK

更新日期：1992-04-01 00:00:00

abstract：:Hydrocarbon ingestions account for a substantial number of accidental poisonings; when aspirated, it can lead to severe pneumonitis. Treatment for severe pneumonitis is generally supportive, and outcomes are frequently poor. We report here the case of a 19-month-old girl who was treated successfully with early adminis...

journal_title：Pediatrics

authors： Mastropietro CW,Valentine K

更新日期：2011-06-01 00:00:00

abstract：:Nonfamilial cardiomyopathies in childhood have been only sporadically ascribed to endocrine disorders. We report on a 4-month-old male infant presenting with Cushing's syndrome associated with excessive body weight (8.9 kg; >97th percentile) and features of virilization (Tanner stage 2 for pubic hair development). Abd...

journal_title：Pediatrics

authors： Hauser J,Riedl S,Michel-Behnke I,Minkov M,Perneczky E,Horcher E

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To identify vaccination policies and beliefs associated with practice immunization rates (PIR) among office-based pediatricians. METHODS:Primary care pediatricians recruited from the Pediatric Research in Office Settings (PROS) network of the American Academy of Pediatrics or the Pediatric Section of the Nat...

journal_title：Pediatrics

authors： Taylor JA,Darden PM,Brooks DA,Hendricks JW,Baker AE,Wasserman RC

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:We sought to determine the prevalence and sociodemographic characteristics of tattooed adolescents in a nationally representative sample and to evaluate the association between tattooing and several high-risk behaviors. METHODS:This is a secondary analysis of the National Longitudinal Survey of Adolescent H...

journal_title：Pediatrics

authors： Roberts TA,Ryan SA

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Health-e-Access, a telemedicine service providing care for acute illnesses in children, has delivered >6500 telemedicine visits from 10 primary care practices in Rochester, New York, by using telemedicine access at 22 child care and school sites. The goal was to assess the hypotheses that children served by H...

journal_title：Pediatrics

authors： McConnochie KM,Wood NE,Herendeen NE,Ng PK,Noyes K,Wang H,Roghmann KJ

更新日期：2009-06-01 00:00:00