Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome.

Abstract:

:A 3.5-year-old healthy boy with 4 days of fever was referred to the emergency department for respiratory distress. The physical examination was remarkable for stupor, tachycardia, tachypnea, and dyspnea. Initial blood tests showed pancytopenia. He rapidly developed torticollis. Computerized tomography of the neck revealed a thrombus in the internal jugular vein. A presumptive diagnosis of Lemierre's syndrome was made and he was started on antibiotics and anticoagulation. He subsequently developed adult respiratory distress syndrome and required high frequency oscillatory ventilation for 9 days. Blood cultures were positive for Fusobacterium necrophorum. Screening for hypercoagulability revealed 2 known risk factors: a mutation in the prothrombin gene and elevated lipoprotein a.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Schmid T,Miskin H,Schlesinger Y,Argaman Z,Kleid D

doi

10.1542/peds.2004-2505

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

e620-2

issue

5

eissn

0031-4005

issn

1098-4275

pii

peds.2004-2505

journal_volume

115

pub_type

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