Analysis of parametric histogram from dynamic contrast-enhanced MRI: application in evaluating brain tumor response to radiotherapy.

abstract：:Proton NMR spectroscopy of biological fluids has produced interesting results lately. We used the technique to investigate the effects of cryopreservation on primary porcine hepatocytes as successful cryopreservation of primary porcine hepatocytes is of importance to the development of bioartificial liver support syst...

journal_title：NMR in biomedicine

authors： Dabos KJ,Parkinson JA,Hewage C,Nelson LJ,Sadler IH,Hayes PC,Plevris JN

更新日期：2002-05-01 00:00:00

abstract：:Citicoline supplementation has been used to ameliorate memory disturbances in older people and those with Alzheimer's disease. This study used MRS to characterize the effects of citicoline on high-energy phosphate metabolites and constituents of membrane synthesis in the frontal lobe. Phosphorus ((31)P) metabolite dat...

journal_title：NMR in biomedicine

authors： Silveri MM,Dikan J,Ross AJ,Jensen JE,Kamiya T,Kawada Y,Renshaw PF,Yurgelun-Todd DA

更新日期：2008-11-01 00:00:00

abstract：:Signal of lung parenchymal tissue from the living rat and mouse lung was detected at 4.7 T with a good signal-to-noise ratio and motion-suppressed artifacts using a short TE gradient-echo sequence. Neither cardiac nor respiratory gating were applied, and animals respired freely during data collection. Mean T(2)* relax...

journal_title：NMR in biomedicine

authors： Beckmann N,Tigani B,Mazzoni L,Fozard JR

更新日期：2001-08-01 00:00:00

abstract：:133Cs NMR is a valuable tool for non-invasively probing biological systems. As a congener of potassium, it accumulates in the intracellular space, primarily through the action of the Na+-K+ pump (ATPase). In addition, it is possible to resolve the MR signal of 133Cs in different tissue compartments on the basis of che...

journal_title：NMR in biomedicine

authors： Goodman J,Neil JJ,Ackerman JJ

更新日期：2005-04-01 00:00:00

abstract：:Glycine (Gly) has been implicated in several neurological disorders, including malignant brain tumors. The precise measurement of Gly is challenging largely as a result of the spectral overlap with myo-inositol (mI). We report a new triple-refocusing sequence for the reliable co-detection of Gly and mI at 3 T and for ...

journal_title：NMR in biomedicine

authors： Tiwari V,An Z,Ganji SK,Baxter J,Patel TR,Pan E,Mickey BE,Maher EA,Pinho MC,Choi C

更新日期：2017-09-01 00:00:00

abstract：:In this study we aimed to assess the effects of continuous formalin fixation on diffusion and relaxation metrics of the ex vivo porcine heart at 7 T. Magnetic resonance imaging was performed on eight piglet hearts using a 7 T whole body system. Hearts were measured fresh within 3 hours of cardiac arrest followed by im...

journal_title：NMR in biomedicine

authors： Lohr D,Terekhov M,Veit F,Schreiber LM

更新日期：2020-07-01 00:00:00

abstract：:In this methodological paper I report the stereotactic correlation of different magnetic resonance imaging (MRI) techniques [MR angiography (MRA), MRI, blood bolus tagging (STAR), functional MRI, and high-resolution BOLD venography (HRBV)] in patients with cerebral arterio-venous malformations (AVM) and brain tumors. ...

journal_title：NMR in biomedicine

authors： Schad LR

更新日期：2001-11-01 00:00:00

abstract：:In vivo 1H MRS is rapidly developing as a clinical tool for diagnosing and characterizing breast cancers. Many in vivo and in vitro experiments have demonstrated that alterations in concentrations of choline-containing metabolites are associated with malignant transformation. In recent years, considerable efforts have...

journal_title：NMR in biomedicine

authors： Haddadin IS,McIntosh A,Meisamy S,Corum C,Styczynski Snyder AL,Powell NJ,Nelson MT,Yee D,Garwood M,Bolan PJ

更新日期：2009-01-01 00:00:00

abstract：:Encoding of spatial information in magnetic resonance imaging is conventionally accomplished by using magnetic field gradients. During gradient encoding, the position in k-space is determined by a time-integral of the gradient field, resulting in a limitation in imaging speed due to either gradient power or secondary ...

journal_title：NMR in biomedicine

authors： Wright SM,McDougall MP

更新日期：2009-11-01 00:00:00

abstract：:Diffusion tensor MRI (DTI) is a method for the noninvasive assessment of cellular organization and integrity in vivo. In this study, in vivo DTI was performed to demonstrate its ability to reflect photoreceptor cell alignment in adult C57BL/6 wild-type mice. Age-matched retinal degeneration 1 (rd1) mice were employed ...

journal_title：NMR in biomedicine

authors： Chen J,Wang Q,Chen S,Wickline SA,Song SK

更新日期：2011-06-01 00:00:00

abstract：:Elevated brain myo-inositol (m-Ins) concentration (a putative marker of neuroinflammation) has been reported in patients suffering from type 2 diabetes mellitus (T2DM). Obesity alone and T2DM have been found to be associated with a lower concentration of N-acetyloaspartate and N-acetylaspartylglutamate (tNAA, a marker...

journal_title：NMR in biomedicine

authors： Gazdzinski SP,Gaździńska AP,Orzeł J,Redlisz-Redlicki G,Pietruszka M,Mojkowska A,Pacho RA,Wylezol M

更新日期：2018-09-01 00:00:00

abstract：:Magnetic resonance elastography (MRE) is a non-invasive imaging technique used to visualise and quantify mechanical properties of tissue, providing information beyond what can be currently achieved with standard MR sequences and could, for instance, provide new insight into pathological processes in the brain. This st...

journal_title：NMR in biomedicine

authors： Green MA,Bilston LE,Sinkus R

更新日期：2008-08-01 00:00:00

abstract：:During magnetic resonance imaging (MRI) examinations, the average specific absorption rate (SAR) of the whole body is calculated as an index of global energy deposition in biological tissue without taking into account the presence of metallic implants or conductive materials. However, this global SAR calculation is no...

journal_title：NMR in biomedicine

authors： Saniour I,Gaborit G,Perrier AL,Gillette L,Revillod G,Sablong R,Duvillaret L,Beuf O

更新日期：2018-01-01 00:00:00

abstract：:Most ovarian tumors are cystic structures containing variable amounts of fluid. Several studies of ovarian cyst fluid focus on one specific metabolite using conventional assay systems. We examined the potential of (1)H-nuclear magnetic resonance spectroscopy in evaluation of the overall metabolic composition of cyst f...

journal_title：NMR in biomedicine

authors： Boss EA,Moolenaar SH,Massuger LF,Boonstra H,Engelke UF,de Jong JG,Wevers RA

更新日期：2000-08-01 00:00:00

abstract：:Determination of the apparent diffusion coefficient (ADC) of the prostate in men (n = 60) with raised prostate-specific antigen (PSA) or an abnormal digital rectal examination (DRE) prior to transrectal ultrasound (TRUS) guided biopsy using endorectal DWI is reported. Patients were categorized into different groups ba...

journal_title：NMR in biomedicine

authors： Kumar V,Jagannathan NR,Kumar R,Thulkar S,Gupta SD,Dwivedi SN,Hemal AK,Gupta NP

更新日期：2007-08-01 00:00:00

abstract：:The increased magnetic susceptibility effects at higher magnetic fields increase the demands for shimming of the B0 field for in vivo MRI and MRS. Both static and dynamic techniques have been developed to compensate for susceptibility-induced field inhomogeneities. In this study, we investigate the impact of and need ...

journal_title：NMR in biomedicine

authors： Boer VO,Luttje MP,Luijten PR,Klomp DW

更新日期：2014-06-01 00:00:00

abstract：:Localization techniques are considered an indispensable part of the clinical spectroscopy examination. The results are often a marked improvement in diagnostic information (amplification), but because of the introduction of new artifacts and the more prolonged examination time, some of the undoubted advantage is lost ...

journal_title：NMR in biomedicine

authors： Ross B,Narasimhan PT,Tropp J,Derby KS

更新日期：1989-12-01 00:00:00

abstract：:The emergence and rapid development of activatable contrast agents (CAs), whose relaxivity changes in response to the variation of a specific marker in the surrounding physiological microenvironment, have expanded the scope of MRI beyond anatomical and functional imaging to also convey information at the cellular and ...

journal_title：NMR in biomedicine

authors： Tu C,Louie AY

更新日期：2013-07-01 00:00:00

abstract：:Cerebrovascular reactivity (CVR) can give insight into the cerebrovascular function. CVR can be estimated by measuring a blood-oxygen-level-dependent (BOLD) response combined with breath-holding (BH). The reproducibility of this technique has been addressed and existing studies have focused on short-term reproducibili...

journal_title：NMR in biomedicine

authors： Peng SL,Yang HC,Chen CM,Shih CT

更新日期：2020-03-01 00:00:00

abstract：:Modified gradient-echo MR techniques were applied to study the effects of inflow on functional brain imaging studies using visual and motor cortex stimulation. The results demonstrate that the large signal changes, seen in previously reported gradient-echo studies at 1.5-2.0 T, are dominated by direct inflow effects, ...

journal_title：NMR in biomedicine

authors： Duyn JH,Moonen CT,van Yperen GH,de Boer RW,Luyten PR

更新日期：1994-03-01 00:00:00

abstract：:The intrinsic nonuniformities in the transmit radiofrequency field from standard quadrature volume resonators at high field are particularly problematic for localized MRS in areas such as the temporal lobe, where a low signal-to-noise ratio and poor metabolite quantification result from destructive B₁⁺ field interfere...

journal_title：NMR in biomedicine

authors： Snaar JE,Teeuwisse WM,Versluis MJ,van Buchem MA,Kan HE,Smith NB,Webb AG

更新日期：2011-08-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) has been employed for over 2 decades to noninvasively quantify central nervous system diseases/injuries. However, DTI is an inadequate simplification of diffusion modeling in the presence of coexisting inflammation, edema and crossing nerve fibers. We employed a tissue phantom using fixe...

journal_title：NMR in biomedicine

authors： Ye Z,Gary SE,Sun P,Mustafi SM,Glenn GR,Yeh FC,Merisaari H,Song C,Yang R,Huang GS,Kao HW,Lin CY,Wu YC,Jensen JH,Song SK

更新日期：2021-01-01 00:00:00

abstract：:The accuracy and precision of the quantification of metabolite concentrations in in vivo (1) H NMR spectroscopy are affected by linewidth and signal-to-noise ratio (SNR). To study the effect of both factors in in vivo (1) H NMR spectra acquired at ultrahigh field, a reference spectrum was generated by summing nine in ...

journal_title：NMR in biomedicine

authors： Hong ST,Pohmann R

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of gadolinium (III) diethyltriaminepenta-acetic acid (Gd-DTPA) mixed with a fixative on the image contrast between the white and gray matter of the perfusion-fixed mouse brain. A series of microscopic MRI (microMRI) studies using different concentrations of Gd-DT...

journal_title：NMR in biomedicine

authors： Kim S,Pickup S,Hsu O,Poptani H

更新日期：2009-04-01 00:00:00

abstract：:Under normal conditions, the heart mainly relies on fatty acid oxidation to meet its energy needs. Changes in myocardial fuel preference are noted in the diseased and failing heart. The magnetic resonance signal enhancement provided by spin hyperpolarization allows the metabolism of substrates labeled with carbon-13 t...

journal_title：NMR in biomedicine

authors： Yoshihara HAI,Bastiaansen JAM,Karlsson M,Lerche MH,Comment A,Schwitter J

更新日期：2020-03-01 00:00:00

abstract：:In this work we introduce the concept of correlation chemical shift imaging (CCSI). Novel CCSI pulse sequences are demonstrated on clinical scanners for two-dimensional Correlation Spectroscopy (COSY) and Total Correlation Spectroscopy (TOCSY) imaging experiments. To date there has been limited progress reported towar...

journal_title：NMR in biomedicine

authors： Andronesi OC,Gagoski BA,Adalsteinsson E,Sorensen AG

更新日期：2012-02-01 00:00:00

abstract：:A novel polarizer based on the dissolution-dynamic nuclear polarization (DNP) method has been designed, built and tested. The polarizer differs from those previously described by being designed with sterile use intent and being compatible with clinical use. The main features are: (1) an integral, disposable fluid path...

journal_title：NMR in biomedicine

authors： Ardenkjaer-Larsen JH,Leach AM,Clarke N,Urbahn J,Anderson D,Skloss TW

更新日期：2011-10-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy at 1.9 T was used to quantify dolichols, cholesterols, choline-containing phospholipids and double bonds in unsaturated acyl chains in lipid extracts of four types of thyroid tissue [normal (n = 27), papillary cancer (n = 15), adenoma (n = 13) and Basedow disease (n = 6)]. In nor...

journal_title：NMR in biomedicine

authors： Yoshioka Y,Sasaki J,Yamamoto M,Saitoh K,Nakaya S,Kubokawa M

更新日期：2000-11-01 00:00:00

abstract：:A short-echo spectroscopic imaging sequence extended with a frequency-selective multiple-quantum- coherence technique (Sel-MQC) is presented. The method enables acquisition of a complete water-suppressed proton spectrum with a short echo time and filtering of the J-coupling metabolite, lactate, from co-resonant lipids...

journal_title：NMR in biomedicine

authors： Melkus G,Mörchel P,Behr VC,Kotas M,Flentje M,Jakob PM

更新日期：2008-11-01 00:00:00

abstract：:MR spectroscopic imaging (MRSI) at ultra-high field (≥7 T) benefits from improved sensitivity that allows the detection of low-concentration metabolites in the brain. However, optimized acquisition techniques are required to overcome inherent limitations of MRSI at ultra-high field. This work describes an optimized me...

journal_title：NMR in biomedicine

authors： Coello E,Noeske R,Burns BL,Gordon JW,Jakary A,Menze B,Haase A,Larson PEZ,Li Y,Schulte RF

更新日期：2018-11-01 00:00:00