The effect of systemically and locally administered steroids on VIP-like immunoreactive cells in the paraventricular nucleus of adrenalectomized rats.

Abstract:

:Seven days after adrenalectomy (ADX) the number of vasoactive intestinal peptide (VIP)- and corticotropin-releasing factor (CRF)-immunoreactive cells in the parvocellular part of the rat paraventricular nucleus (PVN) increased markedly. Dexamethasone in the drinking water (started immediately after ADX) or its local implantation around the hypothalamic PVN reduced the ADX-induced increase in the number of VIP- and CRF-like immunoreactive neurones. The present results suggest that PVN might be the site at which glucocorticoids inhibit the increase in VIP-positive cells after ADX.

journal_name

Brain Res

journal_title

Brain research

authors

Bartha L,Kiem DT,Makara GB

doi

10.1016/0006-8993(90)91272-i

subject

Has Abstract

pub_date

1990-01-08 00:00:00

pages

323-6

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(90)91272-I

journal_volume

506

pub_type

杂志文章
  • NMDA-receptor mediated electrical epileptogenesis in the organotypic culture of rat hippocampus.

    abstract::Extracellular field recordings were made in CA1 in the hippocampal explant cultures in oxygenated artificial cerebrospinal fluid. Schaffer collaterals were stimulated with 1-s trains of 60 Hz pulses every 10 min. Seizures were reliably elicited with progressive lengthening over 1-2 h. D-APV, an N-methyl-D-aspartate (N...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91171-a

    authors: Shin C,Tamaki Y,Wilson JT,Butler L,Sakaguchi T

    更新日期:1992-08-28 00:00:00

  • Kinetics of phenylalanine transport at the human blood-brain barrier investigated in vivo.

    abstract::In vivo proton magnetic resonance spectroscopy was used to investigate intracerebral phenylalanine (Phe) concentrations in nine patients with classical phenylketonuria (PKU). The study included serial examinations (n = 31; plasma Phe levels: 0.47-2.24 mmol/l) of patients either receiving a Phe-restricted diet (200 mg ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01054-8

    authors: Möller HE,Weglage J,Wiedermann D,Vermathen P,Bick U,Ullrich K

    更新日期:1997-12-19 00:00:00

  • The response of optic tract glia during regeneration of the goldfish visual system. I. Biosynthetic activity within different glial populations after transection of retinal ganglion cell axons.

    abstract::We monitored biosynthetic activity of optic tract glia during regeneration of retinal ganglion cell axons in the goldfish and found that the greatest level of incorporated [3H]thymidine and [3H]leucine occurred in glia by 10-15 days after axotomy. During this period there was a marked increase in the number of oligode...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90624-9

    authors: Giulian D,Iwanij V,Stuckenbrok H

    更新日期:1985-07-22 00:00:00

  • A type of basket cell in superficial layers of the cat visual cortex. A Golgi-electron microscope study.

    abstract::The axonal arborizations of the basket cells in the cerebral neocortex have long been considered as the source of the presynaptic terminals contacting the cell bodies of pyramidal cells. Given that the concept of the cortical basket cell is based upon indirect evidence only, it was deemed worthwhile to re-investigate ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90898-8

    authors: DeFelipe J,Fairén A

    更新日期:1982-07-22 00:00:00

  • Hemorrhagic transformation after fibrinolytic therapy with tissue plasminogen activator in a rat thromboembolic model of stroke.

    abstract::In this study, the effects of early vs. delayed tPA treatment on the development of hemorrhagic transformation was compared in a rat thromboembolic model of stroke. Fibrinolysis was performed by administering tPA intravenously at 2 or 6 h after ischemic onset. Twenty-four hours later, confluent hemorrhagic infarction ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02276-3

    authors: Kano T,Katayama Y,Tejima E,Lo EH

    更新日期:2000-01-31 00:00:00

  • Propagation of hippocampal seizure activity arising from the hippocampus: a local cerebral blood flow study.

    abstract::We studied the propagation of spike discharges and the changes in local cerebral blood flow (LCBF) by means of the electroencephalogram (EEG) and autoradiographs to elucidate the underlying mechanism and the propagation pathway in rats with limbic seizures. Seizures were induced by the unilateral microinjection of kai...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91923-2

    authors: Goto Y,Araki T,Kato M,Fukui M

    更新日期:1994-01-21 00:00:00

  • Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus.

    abstract::Opiates modulate pain perception at a number of different levels within the central nervous system and the importance of synergistic spinal and supraspinal influences have been well documented. In the present study we demonstrate synergistic interactions between the periaqueductal gray and locus coeruleus. Administere...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90772-n

    authors: Bodnar R,Paul D,Pasternak GW

    更新日期:1991-09-06 00:00:00

  • Response properties of units in the lateral geniculate nucleus of the domestic chick (Gallus domesticus).

    abstract::One hundred and four visual units of the (ventral) lateral geniculate nucleus (GL) of chicks (Gallus domesticus) were studied with extracellular microelectrodes. Most were extremely responsive to moving targets even at low speeds (0.1 degrees/sec). They were classified as follows. (1) movement-sensitive units with uni...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(79)90823-0

    authors: Pateromichelakis S

    更新日期:1979-05-11 00:00:00

  • Over expression of amyloid beta-protein reduces the number of neurons in the striatum of APPswe/PS1DeltaE9.

    abstract::The effect of increasing amounts of amyloid beta-protein (Abeta) on the number of neurons in the striatum was investigated in APPswe/PS1DeltaE9 transgenic mice. This mouse model of Alzheimer's disease-like amyloidosis displays an increased expression of Abeta in the brain with age. On the basis of reports of disruptio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.02.025

    authors: Richner M,Bach G,West MJ

    更新日期:2009-04-17 00:00:00

  • Pre- and post-translational regulation of aromatase by steroidal and non-steroidal aromatase inhibitors.

    abstract::Treatment of castrated quail with testosterone (T) reliably activates male copulatory behavior and, at the same time, increases the aromatase activity (AA), the number of aromatase-immunoreactive (ARO-ir) cells and the concentration of aromatase mRNA as measured by RT-PCR in the brain. All these effects can be mimicke...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01008-0

    authors: Foidart A,Tlemçani O,Harada N,Abe-Dohmae S,Balthazart J

    更新日期:1995-12-01 00:00:00

  • Tonic regulation of the activity of noradrenergic neurons in the locus coeruleus of the conscious rat studied by dual-probe microdialysis.

    abstract::In the present study, receptor specific compounds were infused via a microdialysis probe in the vicinity of the right locus coeruleus (LC). During the infusion of these compounds, the extracellular content of noradrenaline was recorded in the ipsilateral medial prefrontal cortex (mPFC) with a second microdialysis prob...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01062-8

    authors: Kawahara Y,Kawahara H,Westerink BH

    更新日期:1999-03-27 00:00:00

  • S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type.

    abstract::S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was designed to examine the pre-treatment effects of SAC on cognitive deficits and oxidative damage in the hippocampus of intracerebroven...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.02.072

    authors: Javed H,Khan MM,Khan A,Vaibhav K,Ahmad A,Khuwaja G,Ahmed ME,Raza SS,Ashafaq M,Tabassum R,Siddiqui MS,El-Agnaf OM,Safhi MM,Islam F

    更新日期:2011-05-10 00:00:00

  • Neonatal clonidine treatment results in long-lasting changes in noradrenaline sensitivity and kindling epileptogenesis.

    abstract::In the present experiment we tested the hypothesis that early interference with noradrenaline transmission can have permanent consequences for brain function in adulthood. Neonatal depletion of noradrenaline by daily subcutaneous injections of clonidine results in supersensitivity to noradrenaline in adult hippocampal...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91824-z

    authors: Gorter JA,Kamphuis W,Huisman E,Bos NP,Mirmiran M

    更新日期:1990-12-03 00:00:00

  • Quantification of extracellular levels of corticosterone in the basolateral amygdaloid complex of freely-moving rats: a dialysis study of circadian variation and stress-induced modulation.

    abstract::Corticosterone influences emotion and cognition via actions in a diversity of corticolimbic structures, including the amygdala. Since extracellular levels of corticosterone in brain have rarely been studied, we characterized a specific and sensitive enzymatic immunoassay for microdialysis quantification of corticoster...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2012.01.010

    authors: Bouchez G,Millan MJ,Rivet JM,Billiras R,Boulanger R,Gobert A

    更新日期:2012-05-03 00:00:00

  • Norepinephrine levels in traumatized spinal cord of catecholamine-depleted cats.

    abstract::This study was designed to elucidate the origin of norepinephrine (NE) measured in spinal cord following trauma. In normal cats the NE concentration at the lesion site increased 63% over control 1 h following experimentally produced blunt trauma (400 g-cm). Spinal cords of adrenalectomized cats were also traumatized, ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(76)90536-9

    authors: Schoultz TW,De Luca DC,Reding DL

    更新日期:1976-06-11 00:00:00

  • Studies on the relationship between Ca2+ efflux from mitochondria and the release of amino acid neurotransmitters.

    abstract::It is known that transmitter release depends upon the entry of calcium ions into the synaptic terminal. Mitochondria have been suggested to play a key role on the regulation of intracellular Ca2+ concentration, thereby influencing transmitter liberation and synaptic transmission. Here we report the stimulatory effect ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90618-6

    authors: Sandoval ME

    更新日期:1980-01-13 00:00:00

  • Spatial frequency-dependent feedback of visual cortical area 21a modulating functional orientation column maps in areas 17 and 18 of the cat.

    abstract::The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2003.11.024

    authors: Huang L,Chen X,Shou T

    更新日期:2004-02-20 00:00:00

  • Identification of a 140 kDa protein of rat presynaptic terminal membranes encompassing the active zones.

    abstract::A polyclonal antiserum raised against the carboxy-terminal 17 amino acids of the rat p185c-neu (anct) reacted with a 140 kDa polypeptide in membranes of synaptosome fractions from neocortex and hippocampus of 11-day-old and adult rats. The same antiserum reacted with a 185 kDa polypeptide in microsome membranes from r...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00981-u

    authors: Stieber A,Chen Y,Gonatas J,Dougall W,Qian X,O'Rourke D,Samanta A,Greene MI,Gonatas NK

    更新日期:1995-11-27 00:00:00

  • Cerebellar afferents in early postnatal rats: a retrograde fluorescence study.

    abstract::The development of afferent projections to the cerebellum was studied by making small (20 nl) injections of True blue into the cerebella of neonatal rats under general anaesthesia. Neurones in all main precerebellar nuclei were labelled even in rats less than one day old. With the exception of the disappearance of sma...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(88)90037-5

    authors: Payne JN,Bower AJ

    更新日期:1988-04-01 00:00:00

  • Studies on the relationship of binding affinity to psychoactive and anticholingergic potency of a group of psychotomimetic glycolates.

    abstract::A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(77)90889-7

    authors: Baumgold J,Abood LG,Aronstam R

    更新日期:1977-03-25 00:00:00

  • Alterations in monoamines and GABA in the ventromedial and paraventricular nuclei of the hypothalamus following cold exposure: a reduction in noradrenaline induces hyperphagia.

    abstract::A microdialysis technique for the in vivo assessment of the monoaminergic and GABAergic levels in the ventromedial (VMN) and paraventricular nuclei (PVN) of the hypothalamus was used in order to examine the activities of neurons that project to the hypothalamic regions and are implicated in the regulation of ingestive...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01796-5

    authors: Ohtani N,Sugano T,Ohta M

    更新日期:1999-09-18 00:00:00

  • Effects of the Ca2+ antagonist nimodipine on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats.

    abstract::Diabetes mellitus can lead to functional and structural deficits in both the peripheral and central nervous system. The pathogenesis of these deficits is multifactorial, probably involving, among others, microvascular dysfunction and alterations in intracellular calcium homeostasis. The present study examined the effe...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.12.025

    authors: Biessels GJ,ter Laak MP,Kamal A,Gispen WH

    更新日期:2005-02-21 00:00:00

  • Pontine respiratory neurons in anesthetized cats.

    abstract::The pontine respiratory neurons (PRG) in the 'pneumotaxic centre' have been hypothesized to contribute to phase-switching of neural respiratory activity, especially in terminating inspiration. To define the neural elements involved in phase-switching, we recorded respiratory neurons extra- and intracellularly in anest...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91025-1

    authors: Dick TE,Bellingham MC,Richter DW

    更新日期:1994-02-14 00:00:00

  • Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice.

    abstract::During normal aging, men experience a significant decline in testosterone levels and a compensatory elevation in levels of gonadotropin luteinizing hormone (LH). Both low testosterone and elevated LH have been identified as significant risk factors for the development of Alzheimer's disease (AD) in men. It is unclear ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2012.05.011

    authors: Rosario ER,Carroll JC,Pike CJ

    更新日期:2012-07-23 00:00:00

  • Colocalization of D1 and D2 dopamine receptor mRNAs in striatal neurons.

    abstract::There is evidence that D1 and D2 dopamine receptor subtypes coexist at the cellular level in the striatum and act synergistically to mediate the effects of dopamine. Other data suggest that these receptor subtypes are largely segregated in different striatal projection pathways. We used in situ hybridization in serial...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90303-5

    authors: Lester J,Fink S,Aronin N,DiFiglia M

    更新日期:1993-09-03 00:00:00

  • A method for recording miniature inhibitory postsynaptic currents in the central nervous system suitable for quantal analysis.

    abstract::Quantal analysis of transmitter release is useful in examining presynaptic mechanisms involved in synaptic transmission. However, in central neurons, the presence of multiple synapses makes it difficult to use the traditional quantal analysis, developed for the neuromuscular transmission. We developed a method to mini...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.02.056

    authors: Singh G,Xu JY,Sastry BR

    更新日期:2008-05-01 00:00:00

  • Interaction between spontaneous and electrically induced convulsions and their short- and long-term effects in the abstinence after chronic barbital treatment in the rat.

    abstract::Male rats were treated with barbital supplied in their drinking water (daily dose around 200 mg/kg) for 50 weeks. When the treatment was stopped (day 0) spontaneous convulsions were monitored for the first 3 days of the abstinence. On day 3 a convulsion was induced by electricity in half of the rats (controls and barb...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90653-4

    authors: Wahlström G

    更新日期:1983-05-05 00:00:00

  • An ERP study of motor compatibility effects in action language.

    abstract::This ERP study explores the brain's response to the manipulation of motor compatibility in action-related language. In Experiment 1 participants read sentences in which a protagonist performed two different manual actions either simultaneously or consecutively (e.g. While/after cleaning the wound he unrolled the banda...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.06.020

    authors: Santana EJ,de Vega M

    更新日期:2013-08-14 00:00:00

  • Nerve growth factor selectively increases cholinergic markers but not neuropeptides in rat basal forebrain in culture.

    abstract::We have previously used organotypic cultures to study mechanisms regulating phenotypic expression of neurotransmitter characters in the brain. Our previous work indicated that nerve growth factor (NGF) specifically increased the activity of choline acetyltransferase (CAT) in striatal cholinergic interneurons. In the p...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91136-x

    authors: Martínez HJ,Dreyfus CF,Jonakait GM,Black IB

    更新日期:1987-06-02 00:00:00

  • Effects of global ischemia and estradiol pretreatment on phosphorylation of Akt, CREB and STAT3 in hippocampal CA1 of young and middle-aged female rats.

    abstract::Transient global ischemia induces selective, delayed neuronal death of pyramidal neurons in the hippocampal CA1. Whereas long term treatment of middle-aged female rats with estradiol at physiological doses ameliorates neuronal death, the signaling pathways that mediate the neuroprotection are, as yet, unknown. Protein...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2012.06.036

    authors: De Butte-Smith M,Zukin RS,Etgen AM

    更新日期:2012-08-30 00:00:00